Current Psychiatric Disorders News and Events | Page 2

Current Psychiatric Disorders News and Events, Psychiatric Disorders News Articles.
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Targeted brain stimulation dulls social pain
Pairing brain stimulation with an emotion management technique blunts negative emotions, according to research recently published in JNeurosci. The combination may improve emotional regulation in people with psychiatric disorders. (2020-12-21)

Researchers discover brain pattern that could improve mental health disorder diagnosis
A pattern in how the brain breaks down tryptophan, a common amino acid consumed through food, was discovered by researchers at UTHealth. (2020-12-17)

Digital trackers for mental health not yet fit for purpose
Digital tracking of people with mental health conditions has the power to transform medical diagnostics and treatment, but its claims need careful scrutiny, says an expert in digital analytics from the University of Bath. (2020-12-15)

Gut microbiota plays a role in brain function and mood regulation
Depression is a mental disorder that affects more than 264 million people of all ages worldwide. Understanding its mechanisms is vital for the development of effective therapeutic strategies. Scientists from the Institut Pasteur, Inserm and the CNRS recently conducted a study showing that an imbalance in the gut bacterial community can cause a reduction in some metabolites, resulting in depressive-like behaviors. These findings, which show that a healthy gut microbiota contributes to normal brain function, were published in Nature Communications on December 11, 2020. (2020-12-11)

Promising treatment for premenstrual dysphoric disorder, PMDD
The mental symptoms of premenstrual dysphoric disorder improve following treatment with a progesterone receptor modulator, as demonstrated by SciLifeLab researcher Erika Comasco and Professor Inger Sundström-Poromaa, Uppsala University. The mechanism of action of the study drug provides insights into the potential molecular mechanisms underlying this psychiatric disorder and its treatment. (2020-12-10)

Psychiatric disorders explain increased risk for self-harm in autism spectrum disorders
A population-based study revealed reasons behind elevated suicide risk, attempted suicides, and other self-harm, which require special health care, among adolescents and young adults with autism spectrum disorders. Comorbid disorders, especially non-affective psychoses and affective and anxiety disorders, explained the risk. (2020-12-10)

New compound related to psychedelic ibogaine could treat addiction, depression
A non-hallucinogenic version of the psychedelic drug ibogaine, with potential for treating addiction, depression and other psychiatric disorders, has been developed by researchers at UC Davis. (2020-12-09)

Youth depression tied to higher risk of 66 diseases and premature death
Depressed children and teenagers have an increased risk of suffering from premature death and a wide range of illnesses later in life. That is according to a large observational study by researchers at Karolinska Institutet in Sweden. The findings highlight the need to look for other potential diseases following childhood or adolescent depression. Other psychiatric conditions, such as anxiety and substance misuse, can explain part of the association. The study is published in JAMA Psychiatry. (2020-12-09)

PTSD with depression may significantly increase risk of early death in women
Women with post-traumatic stress disorder and depression have an almost fourfold greater risk of early death than women without trauma exposure or depression. The findings are particularly relevant during the current pandemic, which is exposing many women to unusually high levels of stress. (2020-12-04)

Anorexia patients tolerate rapid weight gain with meal-based behavioral support
A new study by Johns Hopkins Medicine researchers of adults hospitalized for the eating disorder anorexia nervosa has strengthened the case for promoting rapid weight gain as part of overall efforts. (2020-12-03)

How networks form: Charting the developing brain
Researchers use connectomic mapping in the developing cortex to uncover the developmental wiring rules for inhibitory neurons (2020-12-03)

Use of controversial restrains varies wildly across the Pacific
Despite being considered a form of torture, and policies to reduce or abolish it in place, the use of mechanical restraints in psychiatric settings continues, a University of Otago-led study shows. (2020-12-03)

Common neural circuit and potential target for anxiety and obsessive-compulsive disorder
Anxiety disorders are the most frequent comorbid conditions with obsessive-compulsive disorder. Yet the shared neural substrates and the common effective therapeutic target remain unknown. Scientists at School of Life Sciences, Nanjing University dissect a common glutamatergic neuronal circuit, from the prelimbic prefrontal cortex (PrL) to the nucleus accumbens (NAc) core, involved in both anxiety- and obsessive-compulsive-like behaviors. Targeting histamine H3 heteroreceptor in the terminals of glutamatergic PrL-NAc core projections improves stress-induced anxiety- and obsessive-compulsive-like behaviors. (2020-12-02)

Circadian gene mutation increases self-administration of cocaine in mice
University of Pittsburgh researchers reveal a molecular basis for the deep and fundamental connection between the disruption in circadian rhythms and predisposition to substance abuse. (2020-12-02)

After CDC guidance, little change in opioid prescriptions to those at risk of misuse
Research from Saint Louis University finds that among patients at risk for opioid misuse, the odds of receiving a Schedule II opioid (those with high abuse potential) for non-cancer pain were similar to those not at risk, despite new prescribing guidelines from the Centers for Disease Control (CDC). (2020-12-02)

COVID-19 may deepen depression, anxiety, and PTSD among pregnant and postpartum women
In a new study, researchers from Brigham and Women's Hospital surveyed pregnant women and those who had recently given birth, finding concerning rates of depression, generalized anxiety and post-traumatic stress disorder (PTSD) symptoms, which were found to be exacerbated by COVID-19-related grief and health worries. (2020-12-01)

A large-scale tool to investigate the function of autism spectrum disorder genes
Scientists have developed a technology to investigate the function of many different genes in many different cell types at once, in a living organism. They applied the large-scale method to study dozens of genes associated with autism spectrum disorder, identifying how specific cell types in the developing mouse brain are impacted by mutations. The ''Perturb-Seq'' method is an efficient way to identify potential biological mechanisms underlying disease and is broadly applicable to other organs. (2020-11-30)

Everyday activities enhance personal well-being
Physical activity makes happy and is important to maintain psychic health. Researchers of Karlsruhe Institute of Technology (KIT) and the Central Institute of Mental Health (CIMH) in Mannheim studied the brain regions which play a central role in this process. Their findings reveal that even everyday activities, such as climbing stairs, significantly enhance well-being, in particular of persons susceptible to psychiatric disorders. The study is published in Science Advances (DOI: 10.1126/sciadv.aaz8934). (2020-11-25)

Magnetic brain waves to detect injury and disease
Researchers have designed a new Optically Pumped Magnetometer (OPM) sensor for magnetoencephalography (MEG). The sensor is smaller and more robust in detecting magnetic brain signals and distinguishing them from background noise than existing sensors. Benchmarking tests showed good performance in environmental conditions where other sensors do not work, and it is able to detect brain signals against background magnetic noise, raising the possibility of MEG testing outside a specialised unit. (2020-11-23)

Scientists identify brain cells that help drive bodily reaction to fear, anxiety
UNC School of Medicine discovered that artificially forcing the activity of BNST cells in mice produced an arousal response in the form of dilated pupils and faster heart rate, and worsened anxiety-like behaviors. This helps illuminate the neural roots of emotions, and point to the possibility that the human-brain counterpart of the newly identified population of arousal-related neurons might be a target of future treatments for anxiety disorders and other illnesses involving abnormal arousal responses. (2020-11-23)

Psychosis symptoms linked to impaired information spread in the brain
Altered white matter limits the brain's conscious access to information, potentially contributing to delusions and other psychotic symptoms of mental health disorders, according to new research published in JNeurosci. (2020-11-23)

Risk of mental disorders later in life potentially higher in kids of low-income families
The results gained in a study involving approximately one million Danish children increase the understanding of how socio-economic differences in childhood affect the development of mental disorders in the Nordic countries. (2020-11-20)

Sexual minorities, especially women, who misuse substances more likely to have psychiatric disorders
More than half of lesbian, gay and bisexual individuals who misuse alcohol or tobacco also have a co-occurring psychiatric disorder, compared to one-third of heterosexuals, a new University of Michigan study finds. (2020-11-20)

Study explores sleep apnea, autoimmune disease link
New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies. (2020-11-17)

Blood biomarkers for detecting brain injury in COVID-19 patients
COVID-19 can directly cause neurologic symptoms and long-term neurological disease. Elevations of blood biomarkers indicative of brain injury have been reported in the blood and cerebrospinal fluid of COVID-19 patients. Clinical application of blood biomarkers to improve medical management of COVID-19 patients (2020-11-17)

Suffering in silence: two-thirds of older adults say they won't treat their depression
A new nationwide poll, the GeneSight Mental Health Monitor, shows that nearly two-thirds (61%) of Americans age 65 or older who have concerns about having depression will not seek treatment. In fact, nearly 1 in 3 (33%) seniors who are concerned they might be suffering from depression believe they can ''snap out'' of it on their own. (2020-11-16)

From the inside out - how the brain forms sensory memories
New study identifies a region of the thalamus as a key source of signals encoding past experiences in the neocortex. (2020-11-15)

Link between Alzheimer's disease and gut microbiota is confirmed
In recent years, the scientific community has suspected that the gut microbiota plays a role in the development of the disease. A team from the University and the Hospital of Geneva the National Research and, University and IRCCS SDN Research Center of Naples, confirm the correlation, in humans, between an imbalance in the gut microbiota and the development of amyloid plaques in the brain, which are at the origin of Alzheimer's disease. (2020-11-13)

Children born extremely preterm are more likely to be diagnosed with depression
A study using extensive nationwide registry data showed that girls born extremely preterm, earlier than 28 weeks gestational age, were three times more likely to be diagnosed with depression than peers born close to the expected date of delivery. Increased risk of depression also applied to girls and boys with poor fetal growth born full-term and post-term. The effects of poor fetal growth were more evident with increasing gestational age. (2020-11-12)

'Goldilocks' neonatal immune response may protect against autism
The causes of autism spectrum disorder (ASD) - including genetic and environmental factors - are not entirely understood. New research however, shows that the lowest risk for ASD is associated with mid-levels of an immune marker measured at birth - whereas too much or not enough were linked to increased risk. The study hinges on the idea that the developing brain may be particularly vulnerable to disturbances in immune signaling and exposure to inflammation. (2020-11-10)

Prescriptions of antipsychotic medications in young children is declining
The use of antipsychotics in young children is declining but doctors continue to prescribe these medications off-label for conditions not approved by the Food and Drug Administration and without the recommended psychiatric consultation, a Rutgers study found. (2020-11-09)

Study finds evidence of neurobiological mechanism for hallucinations and delusions
A new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found evidence of a potential neurobiological mechanism for hallucinations and delusions that fits within the hierarchical model of psychosis and can explain their clinical presentation. (2020-11-09)

An Amazonian tea stimulates the formation of new neurons
For centuries, indigenous societies in the Amazon have used ayahuasca, a hallucinogenic tea, for shamanic purposes. A research group led by the Complutense University of Madrid has shown that in animal models, this drink stimulates the formation of neurons and other brain cells, and thus offers a potential therapy for psychiatric disorders and neurodegenerative diseases. (2020-11-06)

Providing a safe environment for psychiatric patients during pandemic
The very heart of inpatient care for psychiatric patients is socialization, group therapy, shared meals, and a standard two people per room. Then COVID-19 hit with the accompanying public health warnings to isolate, socially distance, and wear masks. UTHealth Harris County Psychiatric Center had to ride that line. (2020-11-04)

Excessive alcohol consumption during the COVID-19 pandemic
The full impact of COVID-19 on alcohol use is not yet known, but rates have been rising during the first few months of the pandemic. There's an urgent need for public health and medical responses to address harmful alcohol use. (2020-11-02)

Unravelling the origins of autoimmune psychosis
Anti-NMDAR encephalitis is an autoimmune brain illness that is often mistaken by a psychiatric disorder since it causes psychoses and other behaviour alterations. Despite having these similarities, the illness does not respond to common antipsychotic treatments. (2020-10-29)

Nucleus accumbens recruited by cocaine, sugar are different
In a study using genetically modified mice, a University of Wyoming faculty member found that the nucleus accumbens recruited by cocaine use are largely distinct from nucleus accumbens recruited by sucrose, or table sugar. Because they are separate, this poses the possibility that drug use can be addressed without affecting biologically adaptive seeking of reward. (2020-10-28)

Cleveland Clinic-led research team identifies differences between benign and pathogenic variants
An international team of researchers led by Cleveland Clinic's Lerner Research Institute has performed for the first time a wide-scale characterization of missense variants from 1,330 disease-associated genes. Published in Proceedings of the National Academy of Sciences, the study identifies features associated with pathogenic and benign variants that reveal the effects of the mutations at a molecular level. (2020-10-27)

Neuron-based gene expression study reveals insights on fear and its regulation
The expression of a gene called CREB in certain neurons may function as a switch to regulate feelings of fear and its extinction. (2020-10-26)

Happiness and the evolution of brain size
Serotonin can act as a growth factor for the stem cells in the fetal human brain that determine brain size. (2020-10-23)

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