Current Radiation Oncology News and Events | Page 3

Current Radiation Oncology News and Events, Radiation Oncology News Articles.
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Perspectives of tumor treatment: Researchers investigate combination of carbon ion and immunotherapy
It is still a glance into the future: The combination of carbon ion and immune therapy could become an effective tool in the fight against cancer. Promising results for the potential benefit of this treatment combination have now been published in the journal ''International Journal of Radiation Oncology, Biology, Physics'' of the American Society for Therapeutic Radiation Oncology. The authors are an international team, led by the Biophysics Department at the GSI Helmholtzzentrum für Schwerionenforschung. (2020-11-09)

Boosting treatments for metastatic melanoma
University of Cincinnati clinician-scientist Soma Sengupta, MD, PhD, says that new findings from her and Daniel Pomeranz Krummel's, PhD, team might have identified a treatment-boosting drug to enhance effectiveness of therapies for metastatic cancer and make them less toxic, giving patients a fighting chance at survival and improved quality of life. (2020-11-05)

Nerves keep pancreatic cancer cells from starving
Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online November 2 in Cell. (2020-11-02)

Tunable THz radiation from 3D topological insulator
Wu's research group has been investigating a three-dimensional topological insulator of bismuth telluride (Bi2Te3) as a promising basis for an effective THz system. They recently systematically investigated THz radiation from Bi2Te3 nanofilms driven by femtosecond laser pulses. (2020-11-02)

A versatile photodetector assisted by photovoltaic and bolometric effects
A versatile photodetector based on MoTe2/VO2 heterostructure integrates photovoltaic and bolometric effects. The photodetector can realize three different functional modes including p-n junction, bolometer and Schottky junction, satisfying the demand of ultrasensitive and ultrabroad spectrum response, showing great potential in advanced photodetector. (2020-11-01)

Microbes in the gut could be protective against hazardous radiation exposure
A study by scientists at UNC Lineberger Comprehensive Cancer Center and colleagues showed that mice exposed to potentially lethal levels of total body radiation were protected from radiation damage if they had specific types of bacteria in their gut. They demonstrated that the bacteria mitigated radiation exposure and enhanced the recovery of blood cell production as well as repair of the gastrointestinal tract. (2020-10-30)

Sexual health often overlooked in cancer survivorship care, especially for female patients
A new study points to a need for oncologists to ask their patients about sexual health after chemotherapy, radiation and other cancer treatments. In a survey of nearly 400 cancer survivors, 87% said they experienced sexual side effects, but most also said their oncologist had not formally asked about them. Female patients were especially unlikely to be asked about sexual dysfunction. Findings will be presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-30)

Changes in subcellular traffic increase invasiveness of radioresistant cancer cells
Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy. (2020-10-29)

Towards next-generation molecule-based magnets
Magnets are to be found everywhere in our daily lives, whether in satellites, telephones or on fridge doors. However, they are made up of heavy inorganic materials whose component elements are, in some cases, of limited availability. Now, researchers from the CNRS, the University of Bordeaux and the ESRF (European Synchrotron Radiation Facility in Grenoble) have developed a new lightweight molecule-based magnet, produced at low temperatures, and exhibiting unprecedented magnetic properties. (2020-10-29)

Study of COVID-19 levels in oncology staff suggests need for more extensive testing
A study of oncology staff carried out immediately after the spring peak of the COVID-19 pandemic in the UK indicates that many had been infected with the coronavirus as they tested positive for COVID-19 antibodies. This included staff who did not show any symptoms. (2020-10-29)

Study reveals impact of COVID-19 on oncology staff and their work
A study presented at the NCRI Virtual Showcase reports the results of a survey of oncology staff on their management of patients, their wellbeing and whether they felt valued during the first wave of the COVID-19 pandemic. (2020-10-29)

Direct observation of a single electron's butterfly-shaped distribution in titanium oxide
A research team led by Nagoya University has observed the smeared-out spatial distribution of a single valence electron at the centre of a titanium oxide molecule, using synchrotron X-ray diffraction and a new Fourier synthesis method also developed by the team. The method can determine the orbital states in materials regardless of their physical properties and without the need for difficult experiments or analytical techniques. The work was published recently in Physical Review Research. (2020-10-28)

Racial disparities in treatment for common lung cancer persist despite gains
African American patients with lung cancer are still less likely to receive the most effective treatment for a common type of early stage lung cancer. (2020-10-28)

Validation of ERCC1/2 signature as radiosensitivity biomarker for tumor & normal tissues in NSCLC
A genetic analysis of non-small cell lung cancer (NSCLC) patients on the phase III NRG Oncology RTOG 0617 clinical trial assessing radiation dose discovered that high dose radiation therapy is associated with shorter survival times among patients with a radiation-sensitive genotype in DNA repair pathway. These findings were presented at the virtual edition of the American Society for Radiation Oncology's (ASTRO) Annual Meeting in October 2020. (2020-10-28)

Outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer
Researchers involved in the phase II NRG Oncology RTOG 0526 trial studying low dose rate (LDR) prostate brachytherapy (BT) following local recurrence (LR) after external beam radiotherapy (EBRT) for patients with low-to-intermediate risk prostate cancer reported late Grade 3 gastrointestinal and genitourinary adverse events (AEs) occurring in 14% of trial participants. (2020-10-28)

Cancer treatment without side effects?
Treating cancer without debilitating side effects has long been the holy grail of oncologists, and researchers at the University of California, Irvine and Switzerland's Lausanne University Hospital may have found it. (2020-10-27)

Penn Study supports use of radiation before CAR therapy for multiple myeloma
Administering radiation therapy to multiple myeloma patients waiting for CAR T cells to be manufactured was found to be safe and undisruptive to CAR T therapy. (2020-10-26)

Some rectal cancer patients can safely avoid an aggressive operation
A nonsurgical treatment option for rectal cancer that preserves quality of life is safe for carefully selected patients, according to a new study comparing it with the standard operation. The study results appear online as an 'article in press' on the Journal of the American College of Surgeons website in advance of print publication and were presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

MFS Is a strong surrogate endpoint for OS for men receiving salvage RT for recurrent prostate cancer
An analysis of the phase III NRG Oncology clinical trial RTOG 9601 on men receiving salvage radiotherapy (SRT) following prostatectomy for recurrent prostate cancer indicated that, while biochemical failure (BF) was not a strong surrogate endpoint to determine overall survival (OS), metastasis-free survival (MFS) was in this patient population. (2020-10-26)

Group trial bolsters case for stereotactic radiation for tumors that travel to the lungs
A new study, conducted across 13 medical centers in Australia and New Zealand, strengthens the case for radiation therapy as a treatment for cancer that has begun to spread throughout the body. Findings of the SAFRON II trial (NCT01965223) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

Treating spinal mets with fewer, higher doses of radiation reduces pain more effectively
A new study shows using fewer and higher doses of high-precision radiation therapy is a more effective approach for treating painful spinal tumors than conventional radiation therapy. Findings from the Canadian phase II/III trial (NCT02512965) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

Radiosurgery reduces cognitive decline without compromising survival for pts with 4+ brain mets
Results of a new randomized phase III trial suggest that stereotactic radiosurgery (SRS) should replace whole brain radiation therapy (WBRT) as the standard of care for patients with four or more brain metastases. Results from the clinical trial (NCT01592968) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

Adding advanced PET scans to radiation plans for prostate cancer increases FFS rates
Adding the advanced PET radiotracer fluciclovine to conventional imaging to help guide radiation treatments for recurrent prostate cancer can improve disease-free survival rates, a new study finds. Findings from the randomized phase II/III EMPIRE-1 trial (NCT01666808) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

Effectiveness of gemcitabine & daily RT for bladder preservation in muscle-invasive bladder cancer
Bladder preservation with trimodality therapy can be a safe and effective alternative to cystectomy for selected patients with muscle-invasive bladder cancer. The phase II NRG Oncology NRG-RTOG 0712 trial evaluated two regimens. One was the prior RTOG standard using 5-flourouracil and cisplatin with twice daily radiation (FCT), and the other a regimen of gemcitabine and daily radiation (GD) which had demonstrated efficacy in single institution clinical trials. (2020-10-26)

Photon IMRT treatment group displays no significant survival difference between arms
A preliminary analysis of photon therapy treatment group 1 from the phase II NRG Oncology clinical trial NRG-BN001 indicates that there is no statistically significant overall survival (OS) or toxicity differences between dose-intensification radiation therapy (DI-RT) using intensity-modulated radiation therapy (IMRT) and standard-dose radiation therapy (SD-RT) with temozolomide treatments for patients with newly diagnosed glioblastoma (GBM). (2020-10-26)

Why do certain chemotherapies increase the likelihood of blood cancer?
MSK investigators uncover new findings about the relationship between clonal hematopoiesis in cancer patients and the risk of later developing a treatment-related blood cancer. (2020-10-26)

ASTRO: Proton therapy for lung cancer may help reduce risk of heart diseases
Treating lung cancer patients with proton therapy may help reduce the risk of radiation-induced heart diseases. (2020-10-23)

ASTRO highlights Winship study showing increased failure-free survival in prostate cancer
The EMPIRE-1 trial is the first randomized trial of men with prostate cancer with recurring cancer to show that treatment based on advanced molecular imaging can improve disease-free survival rates. (2020-10-23)

Toward a new staging system for prostate cancer, and why it matters
The development and validation of a staging system for non-metastatic prostate cancer could help doctors and patients assess treatment options, as well as improve clinical trials. (2020-10-22)

ASTRO issues clinical guideline on radiation therapy for rectal cancer
A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides guidance for physicians who use radiation therapy to treat patients with locally advanced rectal cancer. Recommendations outline indications and best practices for pelvic radiation treatments, as well as the integration of radiation with chemotherapy and surgery for stage II-III disease. The guideline, which replaces ASTRO's 2016 guidance for rectal cancer, is published in Practical Radiation Oncology. (2020-10-21)

Genomic differences may be key to overcoming prostate cancer disparities
In a new article published in Clinical Cancer Research, Moffitt Cancer Center researchers describes the immune-oncologic differences in prostate cancer tumors of African American men and how those variations may be exploited to develop more personalized treatment approaches for this population. (2020-10-21)

Immunotherapy combo halts rare, stage 4 sarcoma in teen
The patient, whose tumor responded within two weeks after receiving the combination, resumed normal activity and was in a complete remission at the time of the report. (2020-10-16)

Radiation oncology research and clinical trials to be featured at ASTRO's Annual Meeting
The American Society for Radiation Oncology (ASTRO) announced today the press program for its 2020 Annual Meeting, which will feature studies on cancer treatment advances and discussions of topical issues including COVID-19. Researchers will present their findings via live webcasts on October 26 and 27. Register for press access at www.astro.org/annnualmeetingpress. (2020-10-14)

A new protein discovered that repairs DNA
Our cells have DNA repair systems to defend themselves against this sort of damage. One of these systems is based on a protein, photolysis, which uses blue light to repair DNA damage before it leads to mutations. (2020-10-14)

Virus-mimicking drug helps immune system target cunning cancer cells
UCLA researchers found that a drug that activates the body's natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy. (2020-10-14)

Novel Radioimmunotherapy Reverses Resistance to Commonly Used Lymphoma Drug
A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine. When used in combination with rituximab, 177Lu-lilotomab-satetraxetan was shown to substantially increase rituximab binding and rituximab-mediated antibody-dependent cellular cytotoxicity (ADCC) activity, resulting in significant tumor growth delay in a non-Hodgkin's lymphoma mouse model. (2020-10-08)

Graphene detector reveals THz light's polarization
Physicists have created a broadband detector of terahertz radiation based on graphene. The device has potential for applications in communication and next-generation information transmission systems, security and medical equipment. (2020-10-08)

The propagation of admixture-derived evolutionary potential
Adaptive radiation - the rapid evolution of many new species from a single ancestor - is a major focus in evolutionary biology. Adaptive radiations often show remarkable repeatability where lineages have undergone multiple episodes of adaptive radiation in distant places and at various points in time - implying their extraordinary evolutionary potential. (2020-10-07)

New research explores how super flares affect planets' habitability
New research from the University of North Carolina at Chapel Hill will help astrobiologists understand how much radiation planets experience during super flares and whether life could exist on worlds beyond our solar system. (2020-10-07)

Enhanced reimbursement to oncology clinics increases prescriptions of evidence-based drugs
A pay-for performance program that offers enhanced reimbursement to oncology practices for prescribing high-quality, evidence-based cancer drugs increased use of these drugs without significantly changing total spending on care, Penn Medicine researchers report in a new study published online in the Journal of Clinical Oncology. (2020-10-07)

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