Current Radiation Therapy News and Events

Current Radiation Therapy News and Events, Radiation Therapy News Articles.
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Gut microbiota reveals whether drug therapies work in inflammatory bowel diseases
A study recently completed at the University of Helsinki indicates that the gut microbiota of patients suffering from inflammatory gastrointestinal disorders can be used to predict whether they will benefit from expensive therapies. The study also confirms the key role of therapies that have a beneficial effect on the gut microbiota in inflammatory bowel diseases. (2021-01-26)

Rates of skin cancer have increased dramatically over recent decades
Incidence rates of skin cancer (cutaneous malignant melanoma) have increased more than 550% in males and 250% in females since the early 1980s in England - according to a new study by Brighton and Sussex Medical School (BSMS). (2021-01-26)

Male breast cancer patients face high prevalence of heart disease risk factors
Male breast cancer patients were found to have a high prevalence of cardiovascular conditions, in a small study of this rare patient population presented at the American College of Cardiology's Advancing the Cardiovascular Care of the Oncology Patient Virtual course. (2021-01-25)

Better bundled: new principle for generating X-rays
X-rays are usually difficult to direct and guide. X-ray physicists at the University of Göttingen have developed a new method with which the X-rays can be emitted more precisely in one direction. To do this, the scientists use a structure of thin layers of materials with different densities of electrons to simultaneously deflect and focus the generated beams. The results of the study were published in the journal Science Advances. (2021-01-25)

Study finds shorter radiation regimen safe, effective for men with advanced prostate cancer
UCLA researchers found shortening a traditional 45-day course of radiation to a five-day course delivered in larger doses is safe and as effective as conventional radiation for men with high-risk forms of prostate cancer. (2021-01-25)

How does incident solar radiation affect urban canyons?
Toyohashi University of Technology proposed a numerical bead model to predict the upward-to-downward reflection ratio of glass bead retro-reflective (RR) material purposed for urban heat island (UHI) mitigation and reducing energy consumption. These results will contribute to existing research on the absorption or reflection of solar radiation to improve urban thermal and lighting conditions, and to reduce building energy consumption. (2021-01-25)

University of Cincinnati research unveils possible new combo therapy for head and neck cancer
Researchers at the University of Cincinnati have tested a new combination therapy in animal models to see if they could find a way to make an already effective treatment even better. Since they're using a Food and Drug Administration-approved drug to do it, this could help people sooner than later. (2021-01-22)

Sunbathing after menopause may be harmful
UV-radiation can affect hormone levels of postmenopausal women negatively and this may contribute to several health issues, according to new research from Kai Triebner, University of Bergen, and colleagues. (2021-01-20)

How to find mutated sperm? Just go FISH
A test developed by Berkeley Lab scientists can quickly and easily detect whether sperm cells are carrying chromosomal defects, an advance that will help men who have undergone cancer treatment father healthy children. (2021-01-19)

Dartmouth researchers pilot FLASH radiotherapy beam development for treatment of cancer
A team of researchers led by Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center has produced a 'FLASH' ultra-high-dose rate radiation therapy beam, demonstrating that such a beam can be achieved reversibly on a clinical linear accelerator and delivered to the patient treatment site. FLASH beam radiotherapy improves patient safety by protecting normal tissues from excess damage while still having the same treatment effect on tumor tissues. (2021-01-19)

5G doesn't cause COVID-19, but the rumor it does spread like a virus
Research team investigated how COVID-19 misinformation proliferated using the same epidemiological techniques for modeling disease transmission. (2021-01-19)

Genome editing to treat human retinal degeneration
Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness. Technological advances in gene editing, continuing safety concerns, and strategies to overcome these challenges (2021-01-19)

Biodistribution of AAV gene transfer vectors in nonhuman primate
The biodistribution of adeno-associated virus (AAV) gene transfer vectors can be measured in nonhuman primates using a new method. The method quantifies whole-body and organ-specific AAV capsids from 1 to 72 hours after administration (2021-01-15)

Discovery of a new approach to inhibiting a highly treatment-refractory liver cancer
Blocking placental growth factor (PlGF), a member of the vascular endothelial growth factor family, inhibits the progression of intrahepatic cholangiocarcinoma (ICC) and enhances the efficacy of chemotherapy in mouse models. This novel approach to targeting the connective tissue microenvironment of ICC, a rare but notoriously treatment-resistant form of liver cancer, could pave the way for combination therapies, including chemotherapy and immune checkpoint blockade. (2021-01-12)

Treatment for chronic pain must address both physical and social pain
Physical pain and social pain may be more closely related than previously thought. Social pain, which typically results from interpersonal rejection or abuse, has been viewed as a non-medical response to external factors. However, recent research suggests that some physical and social stress responses may arise because of shared processing in the brain. (2021-01-12)

New hard disk write head analytical technology can increase hard disk capacities
Using synchrotron radiation at SPring-8 - a large-scale synchrotron radiation facility - Tohoku University, Toshiba Corporation, and the Japan Synchrotron Radiation Research Institute (JASRI) have successfully imaged the magnetization dynamics of a hard disk drive (HDD) write head for the first time, with a precision of one ten-billionth of a second. The method makes possible precise analysis of write head operations, accelerating the development of the next-generation write heads and further increasing HDD capacity. (2021-01-07)

Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR
Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR. The new drug combination prolongs overall survival in patients in good general health. No study data are available for other patient groups. (2021-01-05)

Alpha-ray missile therapy: tumor cells attacked from intracellular region
Researchers from Osaka University have innovated a technique of irradiating cancer from within. They tagged α-methyl-L-tyrosine with 211Astatine, an α-emitter, to prepare 211At-AAMT; this radiopharmaceutical was effectively conveyed into cancer cells by the amino acid transporter LAT1. Alpha radiation combines high linear energy transfer with minimal tissue penetration, damaging cancer cells lethally while sparing surrounding normal tissue. This strategy may prove a breakthrough in the management of intractable or advanced cancers. (2021-01-04)

Study explains why patients with cancer spread to the liver have worse outcomes
A new study finds that tumors in the liver siphon off critical immune cells, rendering immunotherapy ineffective. But coupling immunotherapy with radiotherapy to the liver in mice restored the immune cell function and led to better outcomes. (2021-01-04)

Surgery may offer survival advantage in certain metastatic breast cancers
Surgery, in addition to treatments like chemotherapy and radiation therapy, may increase the length of survival for metastatic breast cancer patients, according to Penn State College of Medicine and Penn State Cancer Institute researchers. They studied nearly 13,000 stage four breast cancer patients and found that those who had surgery in addition to their other treatments had a survival advantage over those who had other treatments alone. (2020-12-22)

Inverted fluorescence
Fluorescence usually entails the conversion of light at shorter wavelengths to light at longer wavelengths. Scientists have now discovered a chromophore system that goes the other way around. When excited by visible light, the fluorescent dyes emit light in the ultraviolet region. According to the study published in the journal Angewandte Chemie, such light upconversion systems could boost the light-dependent reactions for which efficiency is important, such as solar-powered water splitting. (2020-12-18)

For college students, skin cancer risk remains high in winter months
New research finds college students could be just as at risk for developing skin cancer in the dead of winter as they are in the middle of summer. (2020-12-17)

Change in global precipitation patterns as a result of climate change
The Earth's climate system is largely determined by the differences in temperature between the tropics and the poles. Global warming is likely to cause global atmospheric circulation to change and progressively revert to a situation similar to that of 5,000 to 10,000 years ago. This is the conclusion of a study published in Nature Communications. (2020-12-17)

Oral hormone therapy shown to significantly alter metabolome of menopausal women
Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women. This finding, which examined blood specimens from the landmark Women's Health Initiative (WHI) study, may help explain the disease risks and protective effects associated with different regimens of hormone therapy. (2020-12-16)

A first-in-human clinical trial shows microbubbles augments radiation in liver cancer patients
Bursting gas-filled microbubbles using ultrasound waves sensitizes tumors to targeted radiation, reducing tumor growth and improving overall survival after treatment. (2020-12-15)

Moffitt identifies genomic and immune indicators that predict lethal outcomes in prostate cancer
Moffitt Cancer Center researchers conducted studies to determine if genomic heterogeneity in tumors from grade 4/5 prostate cancer patients can be exploited to identify patient subsets that are at higher risk for lethal outcomes and that may benefit from targeted treatment strategies. Their results were published in the journal European Urology. (2020-12-15)

Gene therapy for placental insufficiency moves toward the clinic
A new study identified an adenovirus gene therapy vector carrying a VEGF isoform. It can improve uterine blood flow in placental insufficiency. (2020-12-15)

Everything you want to know about sunscreen
From safety and effectiveness to who should use sunscreen and how to apply it, Canadian dermatologists review the latest evidence and guidelines on use of sunscreen. The review, published in CMAJ (Canadian Medical Association Journal), recommends that everyone older than six months of age should use sunscreen to protect against skin cancer (2020-12-14)

Gene could help predict response to cervical cancer treatment
UCLA researchers have identified a potential diagnostic marker that could help predict how likely someone with cervical cancer is to respond to the standard treatment of chemotherapy and radiation. (2020-12-11)

Immunotherapy improves responses w/o reducing quality of life in early breast cancer
Adding an immune checkpoint inhibitor to the standard chemotherapy regimen for patients with early-stage breast cancer places no greater burden on patients' ability to perform day-to-day activities than chemotherapy alone, new research by Dana-Farber/Brigham and Women's Cancer Center investigators shows. (2020-12-10)

Robots could replace real therapy dogs
Robotic animals could be the 'pawfect' replacement for our real-life furry friends, a new study published today by the University of Portsmouth has found. (2020-12-10)

Phase 1 trial assesses whether fecal microbiota transplant impacts cancer patients resistant to immu
In one of the first in-human studies to investigate whether modifying the gut microbiome by a fecal microbiota transplant could make cancer immunotherapy more effective, researchers analyzing this in ten cancer patients with refractory melanoma suggest the treatment can improve patient outcomes. (2020-12-10)

AAV capsid-promoter interactions in the non-human primate brain
The phenomenon of AAV capsid-promoter interaction recently seen in the rat central nervous system has now been shown to occur in the non-human primate brain. This interaction can directly determine cell-specific transgene expression (2020-12-10)

Physicians don't always recognize patients' radiation therapy side effects
Physicians did not recognize side effects from radiation therapy in more than half of breast cancer patients who reported a significant symptom, a new study finds. (2020-12-09)

Under-recognition of symptoms may be common in breast cancer patients receiving radiation
Among patients with breast cancer treated with radiotherapy, under-recognition of symptoms was common in reports of pain, pruritus, edema, and fatigue, with younger patients and Black patients having significantly increased odds of symptom under-recognition. (2020-12-09)

Omitting radiation therapy after breast-conserving surgery may not impact 10-year survival rates for older patients with HR-positive breast cancer
Older patients with hormone receptor-positive breast cancer who did not receive radiation therapy after breast-conserving surgery had higher rates of local recurrence but similar 10-year survival rates when compared to patients who received postoperative radiation therapy, according to updated 10-year data from the PRIME II study, presented at the 2020 San Antonio Breast Cancer Symposium. (2020-12-09)

Single-eye gene therapy improves vision in both eyes of patients with inherited eye disorder
A gene therapy for an inherited eye disorder can ameliorate vision loss in both eyes despite only being injected into one, according to a phase 3 clinical trial involving 37 patients. (2020-12-09)

Cervical cancer survival may improve by targeting senescent "zombie" cells
How well women with cervical cancer respond to treatment and survive correlates with the level of 10 proteins in their blood that also are associated with a ''zombie'' cell state called senescence, Medical College of Georgia scientists report. (2020-12-07)

Aluminium alloy research could benefit manned space missions
Manned space missions in spacecraft made of aluminium that is light yet resistant to radiation could be a step nearer following research involving a world-leading facility at the University of Huddersfield. (2020-12-07)

CAR T cell therapy effective as first-line treatment for high-risk large B-cell lymphoma
A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments. (2020-12-06)

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