Current Restless Legs Syndrome News and Events

Current Restless Legs Syndrome News and Events, Restless Legs Syndrome News Articles.
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How reducing body temperature could help a tenth of all ICU patients
ROCKVILLE, MD - A tenth of all intensive care unit patients worldwide, and many critical patients with COVID-19, have acute respiratory distress syndrome (ARDS). (2021-02-23)

New features of a gene defect that affects muzzle length and caudal vertebrae in dogs
A recent genetic study at the University of Helsinki provides new information on the occurrence of a DVL2 gene defect associated with a screw tail and its relevance to canine constitution and health. The variant was found in several Bulldog and Pit Bull type breeds, and it was shown to result in caudal vertebral anomalies and shortening of the muzzle. The DLV2 variant may also affect the development of the heart. (2021-02-23)

CHOP experts describe types of rashes associated with MIS-C
In a study published in Open Forum Infectious Diseases, researchers at Children's Hospital of Philadelphia (CHOP) describe the array of rashes seen in MIS-C patients at their hospital through late July 2020, providing photos and information that could help doctors diagnose future cases. (2021-02-22)

International study finds increased COVID-19 mortality among adults with Down syndrome
A new study by an international team of researchers found that adults with Down syndrome are more likely to die from COVID-19 than the general population, supporting the need to prioritize vaccinating people with the genetic disorder. (2021-02-22)

This robot doesn't need any electronics
Engineers at the University of California San Diego have created a four-legged soft robot that doesn't need any electronics to work. The robot only needs a constant source of pressurized air for all its functions, including its controls and locomotion systems. The team, led by Michael T. Tolley, a professor of mechanical engineering at the Jacobs School of Engineering at UC San Diego, details its findings in the Feb. 17, 2021 issue of Science Robotics. (2021-02-17)

Study demonstrates the reasons to screen children with cancer for inherited cancer genes
Experts at MSK Kids, the pediatric oncology program at MSK, have found that inherited cancer genes are more common than expected in children with cancer. (2021-02-16)

Hope for children with bow hunter syndrome
DALLAS - Feb. 11, 2021 - Fusing the neck's top two vertebrae can prevent repeat strokes in children with bow hunter syndrome, a rare condition that affects a handful of U.S. pediatric patients each year, UT Southwestern researchers suggest in a recent study. The finding, published online in Child's Nervous System, offers a new way to treat these children and protect them from potentially lifelong neurological consequences. (2021-02-11)

Young and restless, old and focused: Age-differences in mind-wandering
Research from Trinity College Dublin suggests that adults can be more focused, less impeded by anxiety and less mentally restless than younger adults, providing new insight into the influence of the natural ageing process on mind-wandering. (2021-02-10)

Early study points to potential therapeutic avenue for a pair of rare pediatric diseases
Scientists have devised a new approach for detecting and potentially heading off the effects of two rare pediatric diseases before birth. The study, performed in mouse models of the diseases and published today in Cell Reports, represents an important step toward much-needed early interventions for Beckwith-Wiedemann syndrome and Silver-Russell syndrome. (2021-02-09)

The genetic susceptibility of people with Down's syndrome to COVID-19
A study reveals the genetic factors that may expose or protect people with Down syndrome from SARS-CoV-2. TMPRSS2, a gene that codes for an enzyme critical for aiding the entry of SARS-CoV-2 in human cells, had 60% higher levels of expression in Down syndrome. The researchers also found higher expression levels for CXCL10, a gene that can trigger cytokine storms. The authors call to vaccinate people with Down syndrome against COVID-19 as a priority. (2021-02-08)

Deadly white-nose syndrome changed genes in surviving bats
Scientists have found genetic differences between bats killed by white-nose syndrome and bats that survived, suggesting that survivors rapidly evolve to resist the fungal disease, according to a Rutgers-led study with big implications for deciding how to safeguard bat populations. (2021-02-04)

Battling bugs help solve mysteries of weapon evolution
Scientists at the University of Arizona outfitted bugs with body armor and pitted them against each other in staged wrestling matches, all in the name of science. The findings shed light on how evolution has shaped the arsenal of weapons in the animal kingdom. (2021-02-04)

New technique identifies important mutations behind Lynch Syndrome
A Michigan Medicine team describes a method for screening so-called genetic variants of uncertain significance in the hopes of identifying those mutations that could cause cancer. (2021-01-29)

First hybrid gene therapy shows early promise in treating long QT syndrome
In a new study published in Circulation, Mayo Clinic researchers provide the first preclinical, proof-of-concept study for hybrid gene therapy in long QT syndrome, a potentially lethal heart rhythm condition. (2021-01-28)

Rare genetic syndrome identified, caused by mutations in gene SATB1
Variations in the gene SATB1 have been shown to cause a rare genetic syndrome. Different variations across the gene lead to varied effects on the cell, leading to a difference in the severity of neurodevelopmental disorders. Discovery of this genetic syndrome is hoped to provide information to families and individuals affected by SATB1-syndrome. (2021-01-28)

Over half of cannabis users with Parkinson's disease report clinical benefits
With medicinal cannabis now legalized in many parts of the world, there is growing interest in its use to alleviate symptoms of many illnesses including Parkinson's disease (PD). According to results of a survey of PD patients in Germany in the Journal of Parkinson's Disease, over 8% of patients with PD reported using cannabis products and more than half of those users (54%) reported a beneficial clinical effect. (2021-01-26)

How insects activate muscles to adapt to limbs removed
Adaptability explains why insects spread so widely and why they are the most abundant animal group on earth. Insects exhibit resilient and flexible locomotion, even with drastic changes in their body structure such as losing a limb. (2021-01-14)

Journal of Clinical Sleep Medicine collection highlights 15 years of scientific discovery
Editors of the Journal of Clinical Sleep Medicine have identified some of the most significant articles in the publication's history, publishing new commentaries on them in a special 15th anniversary collection. The 15 commentaries from associate editors and members of the journal's editorial board describe the impact of the selected articles both at the time of their publication and today. (2021-01-14)

Approximately half of AD dementia cases are mild, one-fifth are severe
What percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are the majority suffering with moderate dementia? A new study using data from the Framingham Heart Study (FHS) sheds light on these trends. (2021-01-13)

Study of flowers with two types of anthers solves mystery that baffled Darwin
Most flowering plants depend on pollinators such as bees to transfer pollen from the male anthers of one flower to the female stigma of another flower, enabling fertilization and the production of fruits and seeds. Bee pollination, however, involves an inherent conflict of interest, because bees are only interested in pollen as a food source. A new study describes a pollination strategy involving flowers with two distinct sets of anthers that differ in color, size, and position. (2021-01-12)

Pillar-like molecules as biosensors for metabolites
Researchers at Kanazawa University report in Communications Chemistry that a molecule known as pillar[6]arene can form a host-guest compound with a cancer-associated metabolite. The phenomenon can be used to efficiently detect the metabolite in crude biological samples, which is important for preventing and treating metabolic syndrome and associated pathologies. (2021-01-11)

Study: New insights on the role of the MLL4 gene in Kabuki syndrome
Research suggests that MLL4 controls the production of neurons that secrete growth hormone-releasing hormone (GHRH) in a part of the brain called the hypothalamus. (2021-01-11)

Bats with white-nose syndrome prefer suboptimal habitats despite the consequences
Bats are mistakenly preferring sites where fungal growth is high and therefore their survival is low. (2021-01-08)

Perceiving prosthesis as lighter thanks to neurofeedback
Transmitting sensory signals from prostheses to the nervous system helps leg amputees to perceive prosthesis as part of their body. While amputees generally perceive their prostheses as heavy, this feedback helps them to perceive the prostheses as significantly lighter, ETH researchers have shown. (2021-01-08)

A subtle change in the DNA may predispose to polyneuropathy after gut infection
Researchers from Tokyo Medical and Dental University (TMDU) identified a novel genetic variant associated with Guillain-Barré syndrome (GBS). By analyzing the DNA sequence of patients with the disease, the researchers identified two novel variants of the ganglioside-binding protein Siglec-10 accumulated in the patients. They found that one of these variants impairs the function of the protein, predisposing carriers to the development of GBS. This study improves our understanding of the pathophysiology of GBS. (2021-01-07)

A brain mechanism underlying 'vision' in the blind is revealed
Researchers observed slow spontaneous fluctuations in the brain's visual centers that preceded visual hallucinations in blind people. (2021-01-07)

New research finds ginger counters certain autoimmune diseases in mice
The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus. (2021-01-06)

Some English bulldogs thought to have cancer may have newly identified syndrome
Some English bulldogs diagnosed with a common cancer may instead have a newly described, non-cancerous syndrome called polyclonal B?cell lymphocytosis. The discovery was made by Morris Animal Foundation-funded researchers at Colorado State University during a study to better understand B-cell chronic lymphocytic leukemia (BCLL). The team published their findings in the Journal of Veterinary Internal Medicine. (2021-01-05)

Metabolic syndrome 'interacts' with COVID-19
Announcing a new publication for BIO Integration journal. In this review article the authors Zeling Guo, Shanping Jiang, Zilun Li and Sifan Chen from Sun Yat-Sen University, Guangzhou, China review how metabolic syndrome 'interacts' with COVID-19. (2020-12-23)

Scientists pinpoint molecular cause for severe disorder in children
A team of scientists from the University of Ottawa have opened a window into the cause of a rare genetic disorder that causes mortality in young children. (2020-12-22)

Getting into shape pre-surgery to aid recovery for older patients - study
Older adults about to undergo elective surgery should undertake a sustained programme of targeted exercise beforehand to counteract the muscle-wasting effects of bedrest, new research suggests. (2020-12-20)

The 'crazy beast' that lived among the dinosaurs
New research published today in the Journal of Vertebrate Paleontology describes a bizarre 66 million-year-old mammal that provides profound new insights into the evolutionary history of mammals from the southern supercontinent Gondwana - recognized today as Africa, South America, Australia, Antarctica, the Indian subcontinent, and the Arabian Peninsula. (2020-12-18)

Prenatal testing has halved the number of babies born with Down syndrome in Europe
For the first time, a study has aggregated data on the number of babies born with Down syndrome in each European country. Researchers estimate the number of people with Down syndrome alive each year between 1950 and 2015. It is critical to have accurate estimates of the prevalence of Down syndrome so each country can evaluate the impact of prenatal testing on its population and to allocate appropriate resources to its citizens with Down syndrome. (2020-12-18)

Water may be an effective treatment for metabolic syndrome
Researchers at the University of Colorado Anschutz Medical Campus have discovered that fructose stimulates the release of vasopressin, a hormone linked to obesity and diabetes. They also found that water can suppress the hormone and alleviate these conditions in mice. (2020-12-15)

How poor oral hygiene may result in metabolic syndrome
Researchers from TMDU identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body. (2020-12-08)

Rutgers reports first instance of COVID-19 triggering recurrent Guillain-Barré Syndrome
Researchers at Rutgers Robert Wood Johnson Medical School have reported the first instance of COVID-19 triggering a recurrence of Guillain-Barré Syndrome - a rare disorder where the body's immune system attacks nerves and can lead to respiratory failure and death. (2020-12-08)

The gut microbiome in polycystic ovary syndrome and its association with metabolic traits
University of Tartu researchers and their collaborators from Finland and Spain investigated the relationship between the gut microbiome and polycystic ovary syndrome. Their study revealed that women with polycystic ovary syndrome in their late reproductive years have significant microbial changes in gut-related to their metabolic health. (2020-12-08)

Gestational age linked to ADHD in children with Down syndrome
A new study by the UC Davis MIND Institute finds a connection between gestational age and ADHD in children with Down syndrome. An earlier gestational age is linked to higher ADHD symptoms later in childhood. (2020-12-04)

Post-COVID pain or weakness? Request an ultrasound or MRI
A new Northwestern Medicine study shows how advanced imaging technology can pinpoint what may have caused patients' nerve damage and help determine the best course of treatment. (2020-12-01)

New childhood dementia insight
Is the eye a window to the brain in Sanfilippo syndrome, an untreatable form of childhood-onset dementia, Australian researchers ask in a new publication. The findings of the NHMRC-funded project, just published in international journal Acta Neuropathologica Communications, highlight the potential for using widely available retinal imaging techniques to learn more about brain disease and monitor treatment efficacy. (2020-12-01)

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