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Current Retina News and Events, Retina News Articles.
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Discovery holds potential for reversing vision loss
Scientists at the Oklahoma Medical Research Foundation have identified a compound that could reverse the vision loss that occurs when blood vessels in the eyes of premature infants and adults grow out of control. (2020-10-05)

First 'pathoconnectome' could point toward new treatments for neurodegenerative diseases
Scientists from the John A. Moran Eye Center at the University of Utah have achieved another first in the field of connectomics, which studies the synaptic connections between neurons. The lab has produced the first pathoconnectome, showing how eye disease alters retinal circuitry. (2020-09-29)

How night vision is maintained during retinal degenerative disease
New insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time has been published today in the open-access eLife journal. (2020-09-22)

Real neurons are noisy. Can neural implants figure that out?
Signals sent from the retina to the brain have a lot of background noise, yet we see the world clearly. Duke researchers show that to achieve visual clarity the brain must accurately measure how this noise is distributed across neurons when processing the signals sent down the optic nerve. These results are likely to shape the design of future retinal prosthetics and other brain-machine interfaces. (2020-09-15)

Seeing the eye like never before
In a big step for ophthalmology, scientists created a method to view the inner workings of the eye and its diseases at the cellular level. Currently, researchers can only see a broad section of the retina. This new technology allows them to zoom into just one part of a cell. In their words, they have accelerated the process for vision restoration. (2020-09-10)

Levodopa may improve vision in patients with macular degeneration
Investigators have determined that treating patients with an advanced form of age-related macular degeneration (AMD) with levodopa, a safe and readily available drug commonly used to treat Parkinson's disease, stabilized and improved their vision. It reduced the number of treatments necessary to maintain vision, and as such, will potentially reduce the burden of treating the disease, financially and otherwise. Their findings appear in The American Journal of Medicine, published by Elsevier. (2020-09-10)

LSU Health study 1st to show nonharmful stress protects against disease in offspring
Research led by Jeff Gidday, PhD, Professor of Ophthalmology, Biochemistry, Neuroscience, and Physiology at LSU Health New Orleans School of Medicine, reports what is believed to be the first study in a mammalian model documenting the reprogramming of heritability to promote disease resilience in the next generation. (2020-09-10)

USTC deciphers transcriptomic atlas of aging human and macaque retina
The work which provides valuable basic for the molecular regulation of aging progression and related diseases, was published in National Science Review on Aug. 25, 2020. (2020-09-06)

Seeing progress
As we get older, many of our body's processes start slowing down. For instance, a cut on the hand will take longer to heal after middle age than in youth. That said, it still heals. (2020-09-03)

Gene therapy: Novel targets come into view
Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that targeted activation of genes of similar function can compensate for the primary defect. (2020-09-02)

Promising discovery for patients with diabetic retinopathy
A study published in the journal Science has shed light on a cellular process that occurs in the retinas of people with diabetic retinopathy. This discovery could lead to the development of a treatment for this serious complication of diabetes. (2020-08-20)

Artificial intelligence recognizes deteriorating photoreceptors
A software based on artificial intelligence (AI), which was developed by researchers at the Eye Clinic of the University Hospital Bonn, Stanford University and University of Utah, enables the precise assessment of the progression of geographic atrophy (GA), a disease of the light sensitive retina caused by age-related macular degeneration (AMD). (2020-08-13)

Nanotubes in the eye that help us see
A new mechanism of blood redistribution that is essential for the proper functioning of the adult retina has just been discovered in vivo by researchers at the University of Montreal Hospital Research Centre (CRCHUM). (2020-08-12)

Young nearsighted kids benefit from bifocal contact lenses, study shows
Bifocal contact lenses aren't just for aging eyes anymore. In nearsighted kids as young as 7 years old, multifocal contact lenses with a heavy dose of added reading power can dramatically slow further progression of myopia, new research has found. (2020-08-11)

Multifocal contact lenses slow myopia progression in children
Children wearing multifocal contact lenses had slower progression of their myopia, according to results from a clinical trial funded by the National Eye Institute, part of the National Institutes of Health. The findings support an option for controlling the condition, also called nearsightedness, which increases the risk of cataracts, glaucoma and retinal detachment later in life. Investigators of the Bifocal Lenses In Nearsighted Kids (BLINK) Study published the results August 11 in the Journal of the American Medical Association. (2020-08-11)

New treatment targets found for blinding retinal disease
When the eye isn't getting enough oxygen in the face of common conditions like premature birth or diabetes, it sets in motion a state of frenzied energy production that can ultimately result in blindness, and now scientists have identified new points where they may be able to calm the frenzy and instead enable recovery. (2020-08-10)

Practice patterns, responsiveness to common ocular complaints among ophthalmology centers during COVID-19
Practice patterns for common ocular complaints during the initial stage of the COVID-19 pandemic are reported in this observational study among comprehensive U.S. ophthalmology practices. (2020-08-05)

Not just light: The sensitivity of photoreceptors to mechanical stimuli is unveiled
''We thought we knew almost everything about photoreceptors, but we have proved that is not the case''. With these words, Vincent Torre, Professor of neurobiology of SISSA, comments the results of a new study that, thanks to a multidisciplinary approach and to the use of optical tweezers, reveals for the first time the sensitivity of nerve cells present on the retina to mechanical stimuli and opens up new questions on how they function. The work has been published in PLOS Biology. (2020-07-27)

Is what I see, what I imagine? Study finds neural overlap between vision and imagination
In Current Biology, Medical University of South Carolina researchers report the results of a study using artificial intelligence and human brain studies to compare brain areas involved in mental imagery and vision. Their findings suggest that mental imagery and vision are similar, but that low-level visual areas are activated in a less precise manner with mental imagery. This suggests that the brain is more tuned and sensitive to what it sees than what it imagines. (2020-07-10)

Researchers uncover a critical early step of the visual process
The key components of electrical connections between light receptors in the eye and the impact of these connections on the early steps of visual signal processing have been identified for the first time, according to research published today in Science Advances by The University of Texas Health Science Center at Houston (UTHealth). (2020-07-08)

Scientists use nanoparticle-delivered gene therapy to inhibit blinding eye disease in rodents
In experiments in rats and mice, two Johns Hopkins scientists -- an engineer and an ophthalmologist -- report the successful use of nanoparticles to deliver gene therapy for blinding eye disease. A uniquely engineered large molecule allows researchers to compact large bundles of therapeutic DNA to be delivered into the cells of the eye. (2020-07-07)

Machine learning helps grow artificial organs
Researchers from the Moscow Institute of Physics and Technology, Ivannikov Institute for System Programming, and the Harvard Medical School-affiliated Schepens Eye Research Institute have developed a neural network capable of recognizing retinal tissues during the process of their differentiation in a dish. Unlike humans, the algorithm achieves this without the need to modify cells, making the method suitable for growing retinal tissue for developing cell replacement therapies to treat blindness and conducting research into new drugs. (2020-07-07)

Nanotechnology applied to medicine: The first liquid retina prosthesis
Researchers at Istituto Italiano di Tecnologia has led to the development of an artificial liquid retinal prosthesis to counteract the effects of diseases such as retinitis pigmentosa and age-related macular degeneration that cause the progressive degeneration of photoreceptors of the retina, resulting in blindness. The collected data show that this innovative technique is valid to restore the photoreceptive capacity of retinal neurons while preserving their spatial resolution, laying a solid foundation for future clinical trials in humans. (2020-06-29)

New eye drops may prevent a common cause of blindness
New eye drops could prevent vision loss after retinal vein occlusion, a major cause of blindness for millions of adults, a study by Columbia University researchers has found. (2020-06-29)

Declining eyesight improved by looking at deep red light
Staring at a deep red light for three minutes a day can significantly improve declining eyesight, finds a new UCL-led study, the first of its kind in humans. (2020-06-28)

Towards an AI diagnosis like the doctor's
Artificial intelligence is an important innovation in diagnostics, because it can learn to recognize abnormalities that a doctor would also label as a disease. But the way these systems work is opaque, and doctors have a better ''overall picture'' when they make the diagnosis. In this publication, Radboudumc researchers show how they can make the AI show how it's working, as well as let it diagnose more like a doctor, thus making AI more relevant to clinical practice. (2020-06-24)

The mystery of visual stability
We move our eyes several times per second. These fast eye movements, called saccades, create large image shifts on the retina -- making our visual system work hard to maintain a stable perceptual world. Remapping the retinal image compensates for this; however, errors in actual eye movements cause image shifts, even with remapping. (2020-06-11)

A vitamin A analog may help treat diabetic retinopathy
Diabetic retinopathy is a common complication of diabetes and a leading cause of blindness among the working-age population. A new study in The American Journal of Pathology reports that visual function in diabetic mice was significantly improved after treatment with a single dose of visual chromophore 9-cis-retinal, a vitamin A analog that can form a visual pigment in the retina cells, thereby producing a light sensitive element of the retina. (2020-06-11)

Retinitis pigmentosa research probes role of the enzyme DHDDS in this genetic disease
Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, expected to see retinal degeneration and retinal thinning. As reported in the journal Cells, they surprisingly found none, calling into question the commonly accepted -- though never proved -- mechanism for RP59. (2020-06-11)

HKUST scientists develop world's first spherical artificial eye with 3D retina
An international team led by HKUST scientists has developed the world's first 3D artificial eye with capabilities better than existing bionic eyes and in some cases, even exceed those of the human eyes, bringing vision to humanoid robots and new hope to patients with visual impairment. (2020-06-10)

Restoring vision by gene therapy
Latest scientific findings give hope for people with incurable retinal degeneration. (2020-06-04)

'Single pixel' vision in fish helps scientists understand how humans can spot tiny details
Recently discovered 'single-pixel vision' in fish could help researchers understand how humans are able to spot tiny details in their environment -- like stars in the sky. (2020-05-29)

Eye injury sets immune cells on surveillance to protect the lens
The discovery further challenges the accepted scientific dogma that the lens is shut out from the immune protection. (2020-05-26)

Inexpensive retinal diagnostics via smartphone
Retinal damage due to diabetes is now considered the most common cause of blindness in working-age adults. In low- and middle-income countries, an eye examination via smartphone could help to detect changes at an early stage. This is shown by a new study carried out by scientists from the University of Bonn together with colleagues from Sankara Eye Hospital Bangalore (India). The results are published in the journal ''Ophthalmology''. (2020-05-25)

Cutting edge two-photon microscopy system breaks new grounds in retinal imaging
In a recent breakthrough, a team of HKUST scientists developed an adaptive optics two-photon excitation fluorescence microscopy using direct wavefront sensing for high-resolution in vivo fluorescence imaging of mouse retina, which allow in vivo fundus imaging at an unprecedented resolution after full AO correction. (2020-05-20)

Retinal texture could provide early biomarker of Alzheimer's disease
Biomedical engineers at Duke University have devised a new imaging device capable of measuring both the thickness and texture of the various layers of the retina. The advance could be used to detect a biomarker of Alzheimer's disease, potentially offering a widespread early warning system for the disease. (2020-05-14)

Our pupil moves to the rhythm of the environment
Regular processes in the environment improve our eyesight. (2020-05-08)

Scientists identify a potential treatment candidate for early type 2 diabetic retinopathy
Diabetic retinopathy is one of the main vascular complications of type 2 diabetes, and the most common cause of visual deterioration in adults. A new study in The American Journal of Pathology, published by Elsevier, reports on the efficacy of a possible treatment candidate that showed anti-inflammatory and neuroprotective effects on the retina and optic nerve head in early type 2 diabetic retinopathy using a diabetic mouse model. (2020-04-27)

NEI researchers link age-related DNA modifications to susceptibility to eye disease
National Eye Institute (NEI) researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression. The findings, published online April 21 in Cell Reports, suggest that the epigenome could be targeted as a therapeutic strategy to prevent leading causes of vision loss, such as age-related macular degeneration (AMD). (2020-04-21)

Tetracycline-family antibiotics may offer early diagnostic for degenerative eye disease
Utilizing human cadaver retinas containing drusen, the researchers used fluorescence lifetime imaging microscopy (FLIM) to measure the light emission from tetracycline staining within those ocular mineral deposits. (2020-04-21)

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