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Current Retina News and Events, Retina News Articles.
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Researchers restore sight in mice by turning skin cells into light-sensing eye cells
Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision, sidestepping the need for stem cells. The lab-made rods enabled blind mice to detect light after the cells were transplanted into the animals' eyes. (2020-04-15)

Skin that computes
As our body's largest and most prominent organ, the skin also provides one of our most fundamental connections to the world around us. From the moment we're born, it is intimately involved in every physical interaction we have. (2020-04-15)

Researchers find that nicotinamide may help treat fibrotic eye diseases and mitigate vision loss
Nicotinamide can inhibit aggressive cell transformations during wound healing and may be key to the development of therapies to treat fibrotic eye diseases. (2020-04-02)

Scientists show how parasitic infection causes seizures, psychiatric illness for some
In a new study published in GLIA , Virginia Tech neuroscientists at the Fralin Biomedical Research Institute at VTC describe how the common Toxoplasma gondii parasite prompts the loss of inhibitory signaling in the brain by altering the behavior of nearby cells called microglia. (2020-04-02)

Microelectronics for birds
Ornithologists and physicists from St Petersburg University have conducted an interdisciplinary study together with colleagues from Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences and the Biological Station Rybachy of the Zoological Institute of the Russian Academy of Sciences. They have created a micro device, weighing less than a gram, which enables them to disrupt locally the avian magnetic compass. (2020-03-30)

CNIC scientists identify an immunological regulatory circuit that may play a central role in ocular diseases
The study, published in the Journal of Experimental Medicine, opens new perspectives on the study and treatment of vascular diseases of the retina and inflammatory disorders that affect the eye choroid. (2020-03-20)

Disturbed retinal gene function underlying canine blindness
A canine study carried out at the University of Helsinki has described a gene variant in the regulatory region of the retina resulting in the abnormal function of retinal genes and, eventually, in the loss of vision in dogs. The study can benefit the diagnostics and treatment of retinitis pigmentosa, a disease suffered by two million human beings globally. (2020-03-10)

'Primitive' stem cells shown to regenerate blood vessels in the eye
Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes. The findings from this experimental study, they say, advance regenerative medicine techniques aimed at reversing the course of diabetic retinopathy and other blinding eye diseases. (2020-03-09)

Ultra-wide field retinal imaging techniques cannot be used interchangeably
For the evaluation and treatment of diabetic eye disease, research from the Joslin Diabetes Center's Beetham Eye Institute has now shown that one technique, UFW fluorescein angiography, detects over three times more microaneurysms than UWF color imaging. (2020-03-05)

New method gives glaucoma researchers control over eye pressure
Neuroscientists have developed a new method that permits continuous regulation of eye pressure without damage, becoming the first to definitively prove pressure in the eye is sufficient to cause and explain glaucoma. (2020-02-24)

Want to catch a photon? Start by silencing the sun
Researchers at Stevens Institute of Technology have created a 3D imaging system that uses light's quantum properties to create images 40,000 times crisper than current technologies, paving the way for never-before seen LIDAR sensing and detection in self-driving cars, satellite mapping systems, deep-space communications and medical imaging of the human retina. (2020-02-24)

Let there be 'circadian' light
Researchers publishing in Current Biology describe the science behind creating lighting to make us all happy and productive indoors. A company is using the technology to create commercial lightbulbs available later this year. (2020-02-20)

New discovery has important implications for treating common eye disease
Scientists from Trinity College Dublin have made an important discovery with implications for those living with a common, debilitating eye disease (age-related macular degeneration, AMD) that can cause blindness. They have discovered that the molecule TLR2, which recognises chemical patterns associated with infection in the body, also seems to play an important role in the development of retinal degeneration. When TLR2 is removed in model systems, a degree of protection is conferred. (2020-02-20)

Autism eye scan could lead to early detection
A new eye scan could help identify autism in children years earlier than currently possible. The non-invasive eye scan utilises a hand-held device to find a pattern of subtle electrical signals in the retina that are different in children on the autism spectrum, which are directly linked to differences in their brain development. (2020-02-20)

Technique can label many specific DNAs, RNAs, or proteins in a single tissue sample
A new technique can label diverse molecules and amplify the signal to help researchers spot those that are especially rare. Called SABER (signal amplification by exchange reaction), Peng Yin's lab at Harvard's Wyss Institute first introduced this method last year and since have found ways to apply it to proteins, DNA and RNA. (2020-02-15)

Microscopic eye movements vital for 20/20 vision
Visual acuity--the ability to discern letters, numbers, and objects from a distance--is essential for tasks including recognizing a friend across a room and driving. Researchers previously assumed visual acuity was primarily determined by the eye's optics and the retina's anatomy. University of Rochester researchers show that small eye movements humans aren't even aware of making also play a large role in visual acuity. The research may lead to improved treatments for vision impairments. (2020-02-07)

Retina-inspired carbon nitride-based photonic synapses for selective detection of UV light
Researchers at Seoul National University and Inha University in South Korea developed photo-sensitive artificial nerves that emulated functions of a retina by using 2-dimensional carbon nitride (C3N4) nanodot materials. Further, through the photo-sensitive artificial nerves which selectively detected ultraviolet (UV) light and processed the information, smart window platform was demonstrated for in-situ modulation of exposure to UV rays depending on the degree of UV exposure and risk. (2020-02-04)

Light at the end of the tunnel for most individuals with low-vision
Progress in research and technology is giving rise to an optimistic future for compensation and restoration of low vision, according to research in a special issue of Restorative Neurology and Neuroscience, published by IOS Press. Seven studies explore different aspects of vision loss after damage to the retina, optic nerve or brain due to diseases such as glaucoma or optic neuropathy. Remarkable progress is being made to treat conditions of partial blindness that have previously been considered irreversible. (2020-01-22)

Avatar worms help to identify factors that modify genetic diseases
C. elegans worms were genetically edited by CRISPR to introduce human mutations that cause retinitis pigmentaria. The final aim of the project was study which factors influence disease development apart from the main mutation. (2020-01-21)

Cardiac and visual degeneration arrested by a food supplement
Researchers (UNIGE) have identified the SLC6A6 gene, which encodes taurine. When there are pathogenic mutations of the SLC6A6 gene, an individual will suffer from a lack of taurine and will lose his sight and develops a weak heart. They hypothesized that a taurine supplement might make it possible to compensate for this deficiency. The supplement was given to a young girl to help stop the progression of her visual degeneration and to treat her cardiomyopathy. (2020-01-21)

Researchers identify gene with functional role in aging of eye
Researchers say a gene known to be a biomarker of age plays a key role in age-associated functional and anatomical aging in mouse retinas, a finding that has direct relevance to age-related eye diseases. (2020-01-15)

Watching complex molecules at work
A new method of infrared spectroscopy developed at BESSY II makes single-measurement observation and analysis of very fast as well as irreversible reaction mechanisms in molecules feasible for the first time. Previously, thousands of such reactions have had to be run and measured for this purpose. The research team has now used the new device to investigate how rhodopsin molecules change after activation by light -- a process that is the basis of how we see. (2020-01-14)

UNH researchers solve protein structure associated with inherited retinal diseases
UNH Researchers have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness. (2020-01-08)

The brain can combine natural and artificial vision to help treat common form of blindness
Researchers report the discovery of evidence indicating that the brain knows how to integrate natural and artificial vision, while maintaining processing information that is important for vision. The results have implications for better restoration of sight in AMD patients implanted with retinal prosthetic devices and support the hypothesis that prosthetic and natural vision can be integrated in the brain. This could also have implications for future brain-machine interface applications where artificial and natural processes co-exist. (2019-12-26)

Light pollution can suppress melatonin production in humans and animals
Melatonin sets the internal clock. Researchers from Leibniz-Institute of Freshwater Ecology and Inland Fisheries (IGB) in an international team have analyzed data on the impact of light pollution on melatonin formation in humans and vertebrates. They found that even the low light intensities of urban skyglow can suppress melatonin production. (2019-12-19)

Finding your way in the dark depends on your internal clock
Surprising results show how circadian rhythm changes the way mammals can see. Mice can accomplish a vision task better at night than during day. The researchers expected the body's internal clock to alter how strong nerve signals were at night, but discovered that the animal's behavior changed depending on the time of day instead. This opens interesting lines of inqury into how circadian rhythm changes behavior (2019-12-19)

Newly discovered retinal structure may enhance vision for some birds
A newly discovered retinal structure in the eyes of certain kinds of songbirds might help the animals find and track insect prey more easily. (2019-12-17)

Study finds association between poor diet, age-related macular degeneration
Participants who ate a diet high in red and processed meat, fried food, refined grains and high-fat dairy were three times more likely to develop late-stage age-related macular degeneration. (2019-12-11)

Oxygen shaped the evolution of the eye
The light-absorbing retina in the eye has an exceptionally high metabolic rate which must be met by adequate oxygen supply. This study shows that oxygen diffusion constrained retinal morphology of ancestral vertebrates. It further demonstrates that animals that independently evolved good vision, such as birds, fishes and mammals, concurrently evolved new mechanisms to supply oxygen to their retina. This suggests that retinal oxygen supply was a physiological prerequisite for the evolution of the improved eyesight. (2019-12-10)

LSU Health discovers role of 2 proteins in sight and preventing blinding eye diseases
Research led by Nicolas Bazan, MD, Ph.D., Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, has discovered unique patterns of genetic activity that may lead to the development of blinding retinal diseases. (2019-12-10)

Mapping the relay networks of our brain
A team of scientists led by Karl Farrow at NeuroElectronics Research Flanders (NERF, empowered by imec, KU Leuven and VIB) is unraveling how our brain processes visual information. They identified specific roles for distinct neuronal cell types in passing on information from the eye to downstream brain regions that guide behavior. Such knowledge is essential to understand how sensory information guides our actions and decisions. (2019-11-29)

Babies in the womb may see more than we thought
Light-sensitive cells active in the retina even before the fetus can distinguish images may play a larger role in the developing eye and brain than previously thought. Intrinsically photosensitive retinal ganglion cells seemingly help establish blood supply to the retina, circadian rhythms and the pupillary light reflex. UC Berkeley researchers have now discovered that these cells are electrically connected in a network that is able to detect light intensity, suggesting a bigger role in development. (2019-11-25)

Air pollution linked to higher glaucoma risk
Living in a more polluted area is associated with a greater likelihood of having glaucoma, a debilitating eye condition that can cause blindness, finds a new UCL-led study in the UK. People in neighbourhoods with higher amounts of fine particulate matter pollution were at least 6% more likely to report having glaucoma than those in the least-polluted areas, according to the findings published in Investigative Ophthalmology & Visual Science. (2019-11-25)

Environmental enrichment corrects errors in brain development
Environmental enrichment can partially correct miswired neurons in the visual pathway, according to research in mice recently published in eNeuro. (2019-11-25)

Heating techniques could improve treatment of macular degeneration
Age-related macular degeneration is the primary cause of central vision loss and results in the center of the visual field being blurred or fully blacked out. Though treatable, some methods can be ineffective or cause unwanted side effects. (2019-11-23)

Treatments for leading cause of blindness generate $0.9 to $3 billion
A new economic study, published in JAMA Ophthalmology and conducted by USC researchers at the Schaeffer Center for Health Policy & Economics, the Ginsburg Institute for Biomedical Therapeutics, and the Roski Eye Institute, quantifies the benefits of treatment for wAMD. (2019-11-14)

Delivering large genes to the retina is problematic
A new study has shown that a commonly used vector for large gene transfer can success-fully deliver genes to retinal cells in the laboratory, but when injected subretinally into rats it provokes a robust and acute inflammatory response. (2019-11-12)

Scientists explain the origin of brain mapping diversity for eye dominance
In a recent study that will be published in the Journal of Neuroscience on November 14th, researchers found evidence that ocular dominance patterns are diverse because the amount of cortex available to represent each binocular point varies greatly across species and individual animals of the same species. (2019-11-11)

LSU Health research discovers potential new Rx target for AMD and Alzheimer's
Research led by Nicolas Bazan, M.D., Ph.D., Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, found a new mechanism by which a class of molecules his lab discovered may protect brain and retinal cells against neurodegenerative diseases like age-related macular degeneration and Alzheimer's. (2019-11-11)

Research brief: Retinal imaging technology for early detection of Alzheimer's disease
Research update from the University of Minnesota Center for Drug Design on an early detection device for Alzheimer's disease. (2019-11-11)

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