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Current Salicylic Acid News and Events, Salicylic Acid News Articles.
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Study: TXA safe and effective to reduce blood loss in joint replacement surgery
Blood loss and the need for a blood transfusion are major concerns in joint replacement surgery, but a new use for an old drug is proving effective in reducing blood loss and transfusion rates, according to a study at Hospital for Special Surgery. The drug, tranexamic acid, or TXA, has been used for decades in heart surgery, to treat hemophilia and to stop excessive uterine bleeding. (2016-03-01)

From backyard pool chemical to nanomaterial
A molecule used to disinfect water could be key to building a new kind of DNA structure. (2016-03-01)

Depression is more than a mental disorder: It affects the whole organism
This work could explain the significant association that depression has with cardiovascular diseases and cancer, and why people with depression die younger. (2016-03-01)

Zolodrenic acid can prevent early bone loss in HIV patients on antiretroviral therapy
A single dose of the drug zoledronic acid was found to inhibit the bone loss that is common in HIV-infected patients and that is increased during the first two years of treatment with antiretroviral therapy. Bone loss also leads to a higher rate of fracture in HIV-infected individuals. (2016-02-23)

Phase 2 clinical trial to treat rare hereditary muscle disease shows promise
Researchers present the first clinical study that provides evidence that an extended-release sialic acid supplement may stabilize muscle strength in patients with GNE myopathy (GNEM), a rare hereditary, progressive, adult-onset muscle disease. (2016-02-22)

Discovery could lead to new treatment strategy against TB
By uncovering the 3-dimensional structure of an enzyme that is critical for the survival of the bacterium that cause tuberculosis, researchers may be one step closer to developing a new strategy to combat TB infections. (2016-02-16)

Absorption of polyphenolic compounds in mangos shows potential benefits to human health
The absorption, metabolism, and excretion of mango galloyl derivatives have not previously been investigated in humans. In this human pilot trial published in the journal of Molecular Nutrition & Food Research, 11 healthy volunteers consumed 400g/day of mango-pulp for 10 days. The results of this research show that mango has the potential to enhance the diet as a source of gallic acid and gallotannins, which may possess anti-inflammatory and anti-carcinogenic properties. (2016-02-16)

Iowa State engineers develop hybrid technology to create biorenewable nylon
Iowa State's Zengyi Shao and Jean-Philippe Tessonnier are combining the tools of biology and chemistry to create new biorenewable products. Their hybrid conversion technology is featured on the cover of the Feb. 12 issue of the journal Angewandte Chemie International Edition. (2016-02-09)

Protein that switches cancers from inflammation to proliferation identified
PAD4 has been observed in cancers but its role was unclear. An Oxford University team have found that PAD4 citrullinates protein E2F-1, which causes it to form a protein complex with BRD4 that drives expression of inflammatory genes. (2016-02-05)

Paper highlights best practices for omega-3 clinical trials with cardiovascular outcomes
A paper published last week in Prostaglandins, Leukotrienes and Essential Fatty Acids sheds new light on recent neutral studies questioning the benefits of omega-3s for heart health. The paper, 'Conducting Omega-3 Clinical Trials with Cardiovascular Outcomes: Proceedings of a Workshop Held at ISSFAL 2014,' identifies experimental design issues in recent studies that have not demonstrated significant effects of EPA and DHA omega-3s on cardiovascular disease outcomes. (2016-02-02)

Are some people more likely to develop adverse reactions to nanoparticle-based medicines?
The complement system, the human body's first line of defense against blood-borne intruders, is blamed for infusion-related reactions to nanomedicines, but the conventional models used to predict the risk of cardiopulmonary side effects in response to nanopharmaceuticals might not well represent what actually occurs in humans, according to an article in Nucleic Acid Therapeutics. (2016-01-28)

Creating 'greener' wrinkle-resistant cotton fabric
Ironing is a tedious chore, but wearing crumpled clothing is unprofessional. That's why 'wrinkle-resistant' garments have become so popular. But the current methods for making these textiles often release formaldehyde -- a chemical that in large amounts is hazardous to human health -- into the air and water. Now a team reports in ACS Sustainable Chemistry & Engineering a method for making wrinkle-resistant cotton fabrics that is more environmentally friendly and cost effective. (2016-01-27)

New material with built-in vitamin A may reduce scarring
Material can be used to treat damaged blood vessels or to make medical devices with intrinsic healing properties, which could reduce tissue scarring. (2016-01-27)

Microscopic drug 'depots' boost efficacy against tumors in animal model
Biomedical engineering researchers have developed a technique for creating microscopic 'depots' for trapping drugs inside cancer tumors. In an animal model, these drug depots were 10 times more effective at shrinking tumors than the use of the same drugs without the depots. (2016-01-25)

Acid-sensitive molecular changes contribute to the emergence of pandemic influenza
St. Jude Children's Research Hospital scientists have linked increased resistance of hemagglutinin protein to acidic pH with emergence of the 2009 H1N1 pandemic flu virus; the finding may help spot future pandemic viruses. (2016-01-25)

Molecular-like photochemistry from semiconductor nanocrystals
Researchers from North Carolina State University have demonstrated the transfer of triplet exciton energy from semiconductor nanocrystals to surface-bound molecular acceptors, extending the lifetime of the originally prepared excited state by six orders of magnitude. (2016-01-21)

Fatty acids from GM oilseed crops could replace fish oil
Oil from genetically modified (GM) oil seed crops could replace fish oil as a primary source of the beneficial omega 3 fatty acid EPA -- according to new research from the University of East Anglia. Researchers studied the effect in mice of consuming feed enriched with oil from glasshouse-grown genetically engineered Camelina sativa, developed at the agricultural science center Rothamsted Research. The results show that the benefits were similar to those derived from fish oils. (2016-01-20)

Omega 3 levels affect whether B vitamins can slow brain's decline
While research has already established that B vitamin supplements can help slow mental decline in older people with memory problems, an international team have now found that having higher levels of omega 3 fatty acids in your body could boost the B vitamins' effect. (2016-01-19)

Scientists demonstrate basics of nucleic acid computing inside cells
Using strands of nucleic acid, scientists have demonstrated basic computing operations inside a living mammalian cell. The research could lead to an artificial sensing system that could control a cell's behavior in response to such stimuli as the presence of toxins or the development of cancer. (2016-01-18)

Low blood levels of bicarbonate linked to earlier death in healthy older adults
Generally healthy older individuals with normal or high bicarbonate levels in the blood had a similar risk of dying during follow-up, but patients with low bicarbonate had a 24 percent increased risk compared with these groups. (2016-01-14)

Eindhoven student team to build the world's first car powered by formic acid
Building a car that is powered by formic acid. That is the ambition of Team FAST, a new student team from Eindhoven University of Technology. Since formic acid can store hydrogen, an environmentally-friendly fuel, it has more benefits than existing hydrogen or electric powered cars. (2016-01-14)

Researchers work on lowering greenhouse gas emissions from poultry houses
A research team from the University of Delaware, USDA, University of Tennessee and Oklahoma State is looking at how adding alum as an amendment to poultry litter reduces ammonia and greenhouse gas concentrations and emissions, specifically carbon dioxide, in poultry houses. (2016-01-12)

High folic acid intake in aged mice causes a lowered immune response
A study in aged mice shows that excess folic acid intake causes lowered immune function because important immune cells, called natural killer cells, are less effective. (2016-01-11)

Saliva test to detect GHB and alcohol poisonings
Scientists working at Loughborough University, UK, and the University of Cordoba, Spain, have developed a new method for the rapid diagnosis of poisoning in apparently drunk patients. The saliva-based test offers the potential to screen for poisons commonly associated with the cheap or imitation manufacture of alcohol, and γ-hydroxybutyric acid, the so-called 'date rape' drug GHB. The results are published today, Friday, Jan. 8, 2016, in the Journal of Breath Research. (2016-01-07)

Fighting rice fungus
Plant scientists are uncovering more clues critical to disarming a fungus that leads to rice blast disease and devastating crop losses. (2015-12-22)

A metabolic pathway in cyanobacteria could yield better biofuels and bioproducts from photosynthesis
Scientists from the Energy Department's National Renewable Energy Laboratory have discovered that a metabolic pathway previously only suggested to be functional in photosynthetic organisms is actually a major pathway and can enable efficient conversion of carbon dioxide to organic compounds. (2015-12-22)

UK failure to fortify flour with folic acid has caused 2000+ cases of neural tube defect
The UK's failure to fortify flour with folic acid has caused around 2000 avoidable cases of neural tube defects since 1998, concludes research published online in the Archives of Disease in Childhood. (2015-12-17)

Spread of algal toxin through marine food web broke records in 2015
Researchers monitoring the unprecedented bloom of toxic algae along the west coast of North America in 2015 found record levels of the algal toxin domoic acid in samples from a wide range of marine organisms. The toxin was also detected for the first time in the muscle tissue or filet of several commercial fish species. (2015-12-17)

Carnegie's Jones recognized for early career contributions to plant science
Carnegie's Alexander Jones will receive the Tansley Medal for Excellence in Plant Science. The honor includes publishing a minireview, an editorial written about his work in the journal New Phytologist, and a small bursary. (2015-12-17)

Sea lions exposed to algal toxin show impaired spatial memory
California sea lions exposed to the algal toxin domoic acid can suffer brain damage that leads to significant deficits in spatial memory. The new findings suggest that chronic exposure to the toxin, produced by naturally occurring marine algae, causes impairments that are likely to affect sea lions' ability to navigate in their ocean habitat and survive in the wild. (2015-12-14)

Scientists develop diesel that emits far less CO2
Researchers from KU Leuven and Utrecht University have discovered a new approach to the production of fuels. Their new method can be used to produce much cleaner diesel. It can quickly be scaled up for industrial use. In five to 10 years, we may see the first cars driven by this new clean diesel. (2015-12-10)

Portable device can quickly determine the extent of an eye injury
An engineer and an ophthalmologist are developing a portable sensor that can quickly and inexpensively determine whether an eye injury is mild or severe. The device, called OcuCheck, measures levels of vitamin C in the fluids that coat or leak from the eye. The sensor could speed efforts to determine the extent of eye injuries at accident sites or on the battlefield, the researchers said. (2015-12-08)

New research: Intestinal bacteria are affected by antidiabetic drugs
Intestinal bacteria change their composition and function when diabetic patients are treated with the drug metformin. (2015-12-02)

New class of inhibitory compounds developed to aid melanoma treatments
A University of California, Irvine pharmacology researcher has helped create a class of inhibitory compounds that can strongly enhance the effect of anti-tumor drugs for melanoma. (2015-12-02)

Sylvester presents latest cancer research at ASH Annual Meeting
Researchers from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine will present a selection of the latest advances in hematology research at this year's American Society of Hematology Annual Meeting, Dec. 5-8, at the Orange County Convention Center in Orlando, Fla. (2015-12-02)

Fries with a side of acrylamide
French fry lovers, beware! You may be exposed to a chemical more commonly associated with heavy industry than crispy fried potatoes. Fortunately, researchers are finding ways to reduce that exposure. (2015-12-02)

Plant hormone may play a vital role in blood sugar control and diabetes management
A treatment for managing blood sugar levels might be as close as the local health food store, suggests a new research report published in the Dec. 2015 issue of The FASEB Journal. (2015-12-01)

Aspirin targets key protein in neurodegenerative diseases
The active ingredient in aspirin blocks an enzyme that triggers cell death in several neurodegenerative diseases. More potent forms of salicylic aspirin exist, which may provide treatments for these diseases. (2015-11-30)

Rare disease is a lens on cancer
In children, lack of a protein causes a dangerous disease. Why do cancer cells suppress the same protein? (2015-11-26)

Osteoarthritis finding sheds new light on HA injection controversy
A discovery by Cornell University bioengineers is shedding new light on the controversy surrounding a common treatment for osteoarthritis that has divided the medical community over its effectiveness. (2015-11-25)

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