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Current Sepsis News and Events, Sepsis News Articles.
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Multicenter trial supports use of topical antibiotics in NICU babies
A team of doctors led by Karen L. Kotloff, M.D., University of Maryland School of Medicine (UMSOM), Center for Vaccine Development and Global Health (CVD), has performed a clinical trial involving multiple hospitals that tested the effectiveness of applying a topical antibiotic known as mupirocin for prevention of Staphylococcus aureus (SA) infection in babies in the neonatal intensive care unit (NICU). (2018-12-27)
New sepsis treatment a step closer
Australian emergency medicine clinician-researchers are leading a large new study to understand how patients with sepsis are treated in emergency departments. (2018-12-11)
Targeting sepsis, the leading cause of ICU deaths, with a nanocarrier-delivered microRNA
One obstacle to therapeutic use of microRNAs (miRNA), which are in clinical trial for a number of diseases, are ribonucleases, whose job it is to destroy them. (2018-12-03)
Study identifies sepsis symptoms that lead to death
The data analysis, pulled from more than 200,000 hospital visits, could help clinicians to more quickly identify -- and treat- the patients who are at the greatest risk of dying from the common, and often insidious, condition. (2018-11-26)
Screening tools can miss sepsis in pregnancy; study urges action
A woman lies in her hospital bed. Her heart rate is elevated, she has a slight fever and an elevated white blood cell count. (2018-11-21)
New inhibitor which blocks inflammation could also treat sepsis
Scientists from the University of Sheffield have discovered a new inhibitor which decreases lung inflammation and could hold the key to treating Acute Respiratory Distress Syndrome -- a life-threatening disease which affects thousands of people in the UK. (2018-11-17)
UTA researchers find new pathway to regulate immune response, control diseases
Researchers at The University of Texas at Arlington have found a potential new pathway to regulate immune response and potentially control inflammatory diseases of the central nervous system such as meningitis and sepsis. (2018-11-09)
Machine-learning system could aid critical decisions in sepsis care
Researchers from MIT and Massachusetts General Hospital (MGH) have developed a predictive model that could guide clinicians in deciding when to give potentially life-saving drugs to patients being treated for sepsis in the emergency room. (2018-11-06)
Concurrent chemo-radiotherapy should be a treatment option for elderly patients with LS-S
Elderly patients with limited-stage small cell lung cancer (LS-SCLC) showed similar survival and toxicity compared to their younger counterparts when treated with concurrent chemo-radiotherapy. (2018-11-01)
Breakthrough test screens for all known bacterial infections
Scientists at the Center for Infection and Immunity (CII) in the Columbia University Mailman School of Public Health have developed the first diagnostic platform that can simultaneously screen for all known human pathogenic bacteria as well as markers for virulence and antibiotic resistance. (2018-10-23)
AI doctor could boost chance of survival for sepsis patients
Scientists have created an artificial intelligence system that could help treat patients with sepsis. (2018-10-22)
New approach to neonatal sepsis in developing nations could save thousands of lives
Sepsis is a major cause of preventable death among newborn children in tropical countries. (2018-10-22)
Case Western Reserve researchers cure drug-resistant infections without antibiotics
Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice. (2018-10-17)
Klebsiella pneumoniae drug resistance in infants studied in Kazan
In neonates with sepsis testing of K. pneumoniae isolates for ESBL production was positive in 60 percent of cases, in neonates with UTI -- in 40 percent of cases. (2018-10-10)
Path to deadly sepsis varies by bacterial infection
Sepsis remains a common and deadly condition that occurs when the body reacts to an infection in the bloodstream. (2018-10-10)
Tracking a killer
A major cause of human disability and death throughout the world, sepsis is a condition that begins with an infection, progresses rapidly and can set off a chain of effects that result in multiple organ failure and irreparable damage to the body. (2018-10-10)
Inflammation in the womb may explain why some babies are more prone to sepsis after birth
Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders. (2018-10-09)
In childbirth, when to begin pushing does not affect C-section rates
Obstetricians have differing opinions about when women should begin pushing during labor and whether the timing of pushing increases the likelihood of a cesarean section. (2018-10-09)
Mechanical ventilation 'no increased risk' of mortality in pregnant patients
Researchers in Columbia, South America, conducted a retrospective observational study within six hospitals to identify risk factors of maternal mortality in mechanically ventilated pregnant patients. (2018-10-04)
Mortality in septic shock has improved since the Surviving Sepsis Campaign guidelines in 2004
A study from Mount Sinai West concludes that the overall mortality in septic shock has improved in the decade following the introduction of the Surviving Sepsis Campaign (SSC) guidelines. (2018-10-04)
Study finds infection rates on the rise in the USA, particularly among people with diabetes
Infection-related hospitalizations in the USA are on the rise, particularly among people with diabetes, suggesting that more must be done to protect people with diabetes from preventable complications, according to new research being presented at this year's European Association for the Study of Diabetes (EASD) Annual Meeting in Berlin. (2018-10-02)
Clinical early warning scores: New clinical tools in evolution
Doctors and nurses are always grateful when they are given advance notice that a patient is about to seriously deteriorate (or 'crash,' to use today's clinical vernacular). (2018-09-13)
New nanoparticles wait to release drugs, target infection
Current WSU research shows stimuli-responsive nanoparticles can specifically target infections to simultaneously prevent the spread of bacteria and reduce the inflammation it causes. (2018-09-11)
Patients with sepsis at higher risk of stroke, heart attack after hospital discharge
Patients with sepsis are at increased risk of stroke or myocardial infarction (heart attack) in the first 4 weeks after hospital discharge, according to a large Taiwanese study published in CMAJ (Canadian Medical Association Journal). (2018-09-10)
Smart technology to help diagnose sepsis in children in Canada
Smart technology and artificial intelligence could be used to improve detection of sepsis in children in Canada, write authors of a commentary in CMAJ (Canadian Medical Association Journal). (2018-09-10)
New York State sepsis reporting mandate appears to improve care, reduce deaths
A New York State requirement that all hospitals report compliance with protocols to treat severe sepsis and septic shock appears to improve care and reduce mortality from one of the most common causes of death in those who are critically ill, according to a new study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. (2018-09-07)
Researchers stop cell suicide that worsens sepsis, arthritis
Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis. (2018-08-24)
Mucosal environment of older pigs helps newborn piglets with intestinal injury recover
Researchers have found that the intestinal mucosal environment of juvenile pigs can stimulate repair of intestinal injuries in newborn piglets. (2018-08-23)
The medicine of the future against infection and inflammation?
Researchers at Lund University in Sweden, have in collaboration with colleagues in Copenhagen and Singapore, mapped how the body's own peptides act to reduce infection and inflammation by deactivating the toxic substances formed in the process. (2018-08-13)
UCalgary researchers discover why sepsis from a staph infection causes organ failure
Scientists have known for some time that one of the reasons a staph infection is so deadly is that the bacteria send out a toxin, known as Alpha Toxin (AT), which quickly worsens sepsis. (2018-07-25)
Sepsis kills. Prompt care saves kids' lives
More than one in 10 children hospitalized with sepsis die, but when a series of clinical treatments and tests is completed within an hour of its detection the odds of death shrink 40 percent, according to the largest ever analysis of pediatric sepsis. (2018-07-24)
Nosocomial neonatal meningitis with Acinetobacter baumannii on myelomeningocele
In this article, together with a review of the literature, we report two cases of imipenem-resistant Acinetobacter baumannii neonatal meningitis following ruptured myelomeningocele, treated with intravenous colistin with favorable results. (2018-07-13)
Pneumococcal DNA predicts course of infection
Besides the patient's condition, pneumococcal DNA also appears to provide information about the course of an infection. (2018-07-04)
New clues to sepsis may speed diagnosis
Researchers at Columbia University Irving Medical Center have found a clue in understanding how an infection can spiral into sepsis by blunting the body's immune response. (2018-07-03)
Researchers identify key protein involved in triggering inflammation
Researchers from the University of Illinois at Chicago have identified a protein that is crucial for activating inflammation -- both the good kind of inflammation that leads to healing wounds and fighting infection, as well as excessive inflammation where the immune system can damage tissues and organs. (2018-06-27)
Scientists found means to inhibit capillary leakage in sepsis
Leakage from the blood capillaries is a key mechanism leading to septic shock and multiorgan failure, which affect millions of patients annually worldwide. (2018-06-25)
Sepsis-3 criteria 'preferable' in prognostication of critically ill patients
Researchers from the University of Ottawa sought to compare the prognostic accuracy of the Sepsis-3 septic shock criteria with the SIRS-based septic shock criteria for prediction of in-hospital mortality among patients hospitalized with suspected infection, receiving a RRT assessment for acute deterioration. (2018-06-14)
Rapid genetic testing can prevent hearing loss in newborns treated for sepsis
More than a million neonatal deaths worldwide each year are estimated to be due to sepsis. (2018-06-14)
Drug may quell deadly immune response when trauma spills the contents of our cells' powerhouses
When trauma spills the contents of our cell powerhouses, it can evoke a potentially deadly immune response much like a severe bacterial infection. (2018-06-11)
Immunocompromised patients with sepsis may face higher mortality at hospitals treating small numbers
Immunosuppressed patients with sepsis appear more likely to die if they are treated in a hospital caring for a relatively small number of these patients, according to new research published online in the Annals of the American Thoracic Society. (2018-06-01)
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