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Measles infection and and two or more younger siblings seem to protect against asthma
Having measles before the age of 3 and two or more younger siblings seems to protect against asthma, finds a study in Thorax. Exposure to bacteria and viruses in infancy and childhood might be important in protecting against asthma. And protection may be conferred by a particular type of infection that is capable of altering the immune response for years ahead. And that might be the measles virus. (2000-04-18)

Rush conducts nationwide study to find genetic markers for depression
The National Institutes of Mental Health has launched the largest psychiatric genetic study ever attempted to investigate how recurrent depression is passed along through families. While depression is known to be genetically transmitted, discovery of the specific genetic sequence would offer new hope for more accurate diagnoses, better treatment, and the possibility for prevention of the disease. (2000-04-06)

Researchers seek siblings with Parkinson's disease for national genetic study
Researchers are seeking siblings diagnosed with Parkinson's disease to identify the genetic markers that may indicate a predisposition for developing this movement disorder. Indiana University School of Medicine is the principal institution among 49 centers in the U.S., Puerto Rico and Canada participating in five-year PROGENI (Parkinson's Research: The Organized Genetic Initiative)study. (2000-02-27)

Researchers link genetic defect to 'head-rush' disorder
Vanderbilt University Medical Center researchers have identified the first genetic defect in the syndrome of orthostatic intolerance--a disorder that leaves its sufferers with a prolonged (2000-02-23)

People from large families may have greater risk of Alzheimer's
Children in large families may have a greater risk of developing Alzheimer's disease than children from smaller families, according to a study in the January 25 issue of Neurology, the scientific journal of the American Academy of Neurology. (2000-01-24)

Relatives of patients with subarachnoid haemorrhage are at increased risk of condition
First degree relatives of patients who have experienced subarachnoid haemorrhage have a three to fivefold increased risk of suffering the same type of haemorrhage compared with the general population, suggest researchers in this week's BMJ. (2000-01-13)

National Cancer Institute awards cancer center $4.5 million for colon cancer research
The National Cancer Institute (NCI) recently awarded a $4.5 million grant to researchers at the cancer center at Case Western Reserve University's School of Medicine and University Hospitals of Cleveland. The five-year grant will support a project to uncover a new genetic link in the development of colon cancer. (2000-01-04)

Big brother has a lot to answer for
Doctors in Ontario have shown that the youngest of several brothers is more likely to show random asymmetries in his body shape. The researchers believe this is a sign of troubled development in the womb. (1999-12-07)

NIAMS funds the North American Spondylitis Consortium
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) has awarded $4.5 million to establish the North American Spondylitis Consortium (NASC) to search for genes that determine susceptibility to ankylosing spondylitis (AS), a rare but painful inflammatory disease of the spine, primarily affecting men. (1999-09-27)

Camelford water contamination did lead to cerebral function damage
People who were exposed to the contaminated water at Camelford in Cornwall, suffered damage to their cerebral function, argue researchers. Dr Paul Altmann and colleagues say that the damage they found in the people studied was not due to anxiety as had been previously claimed and they call for further research to be undertaken. (1999-09-24)

Mayo Clinic researchers: family history identified as new risk factor for heartburn
Mayo Clinic researchers have concluded that family history, possibly through a genetic link, and obesity are major independent risk factors for heartburn and acid regurgitation, both symptoms of gastroesophageal reflux disease. Upwards of 20 percent of American and European populations are estimated to experience heartburn or acid regurgitation at least once a week. Chronic heartburn and acid reflux may lead to Barrett's esophagus, which may evolve into esophageal cancer. (1999-08-24)

Jefferson scientist hopes to answer the question, 'Why is it so hard to quit smoking?'
Scientists hope to learn why some people can 'go cold turkey' on cigarettes and nicotine, while others remain hooked. They're conducting a clinical trial examining 800 pairs of siblings who smoke at least one pack a day, attempting to tease out the subtleties of nicotine addiction and potential genetic influences. (1999-08-16)

Paediatricians Sometimes Fail To Diagnose Child Abuse
In this week's BMJ, researchers express concern that paediatricians are failing to recognise some injuries resulting from child abuse, and propose that clinical investigations should be more fully investigated. (1998-12-05)

Maternal Tissue Typing Could Improve Selection Of Kidney Transplant Donors
NIH-supported researchers have discovered that cellular markers, or human leukocyte antigens (HLA), on maternal tissue can provide valuable information for identifying the most suitable donors for individuals in need of kidney transplants. (1998-12-04)

Sibling Cord Blood May Offer Best Match Chance For Some Patients
Children needing bone marrow transplants may find their best chance in umbilical cord blood from a sibling, even if the transplant is only partially matched to the recipient's blood type, according to Duke researchers. (1998-12-04)

Cells From Mother Can Boost Success Of Sibling-To-Sibling Kidney Transplants
Kidney transplants between siblings with slightly different tissue types are as much as 28 percent more likely to survive long-term when maternal tissue types are used to determine the donor, a new study from the University of Wisconsin Medical School suggests. (1998-12-02)

Differences In Brain Function Found For Attention Deficit Disorder
Stanford neuroscientists have found a clear difference in brain functioning between boys who have attention deficit disorder and those who do not, which might lead to brain- based methods of diagnosis. They also show for the first time that Ritalin has different effects on the brains of individuals in the two groups (1998-11-23)

Painful Births For Babies Could Lead To Violent Suicide In Adulthood
Minimising pain and discomfort for an infant during birth seems to be of importance in reducing the risk of committing suicide by violent means later in life, claim researchers in this week's BMJ. (1998-11-13)

'DES Daughters' Had Increased Rates of Cancer; An Animal Study Shows 'DES Granddaughters' May Too
Like 'DES daughters,' DES granddaughters may have an increased risk of reproductive tract cancers, an animal study published today suggests. DES, or diethylstilbestrol, is the synthetic estrogen once used in attempts to treat women at risk for miscarriage. Scientists at the National Institute of Environmental Health Sciences report that they have observed an increase in cancers, including cancer of the uterus, in female mice whose mothers were exposed to DES in utero. (1998-09-25)

School Achievement Drops In Larger Families -- Except for Mormons
Previous research showed that increasing the number of children in a family lowers the educational achievement for all siblings. But new research found an intriguing exception among Mormon families. The addition of new children to these families doesn't have the same negative educational effects seen in most of the population. (1998-08-24)

Gene Patterns Can Predict When--But Not Whether--Alzheimer's Will Strike
Scientists at the Johns Hopkins School of Public Health have discovered that one of three normal variants of a gene called apolipoprotein-E (APOE) can be used to predict when a person will get Alzheimer's disease, if that person is predisposed to the disorder in the first place. The study showed that the E-4 variant (or allele) of the APOE gene influenced the timing of the onset of Alzheimer's in about half of the population. (1998-07-27)

Siblings Of People With Heart Disease Are Less Likely To Get Treatment
DALLAS, July 17 -- You may think you're nothing like your brother or sister, but if any of your siblings have heart disease, think again. In a study in this month's Hypertension: Journal of the American Heart Association, brothers and sisters of people who have heart disease before age 60 had a greater risk of developing high blood pressure, a major risk for heart disease. (1998-07-16)

The Rights And Wrongs Of Covert Video Surveillance
Covert video surveillance is an infringement of the liberty of parents and children, writes Professor Colin Morley from Addenbrooke's Hospital, whereas Professor Alan Craft from the University of Newcastle-upon-Tyne says that the needs of the child are paramount and the procedure is only a safeguard for children and their siblings. (1998-05-22)

ACE Gene Linked To High Blood Pressure In Men But Not Women
Researchers have zeroed in on a gene linked to high blood pressure -- a disease that affects one in four adults -- according to two reports in today's Circulation: Journal of the American Heart Association. (1998-05-11)

Taller Does Not Necessarily Mean Happier, A New UB Study Of Growth-Hormone Patients Shows
Although popular culture continues to presume that height is a measure of personal satisfaction in life, a new study by a team of psychologists and endocrinologists at the University at Buffalo refutes the idea that taller is necessarily better. The study appears in the current issue of the Journal of Clinical Endocrinology and Metabolism. (1998-04-13)

Pitfalls Of Puberty: New Animal Research Shows Stress During Adolescence Alters Behavior And Brain Chemistry
New research indicates that exposure to stress during puberty results in abnormal aggressive and submissive behaviors as well as neurobiological alterations in hamsters. (1998-04-08)

Blood Clotting Disorder -- A New Heritable Risk Factor?
Blood clotting abnormalities, which have emerged as a potential risk factor for heart disease and stroke, appear to run in families, according to two studies reported today at the American Heart Association's epidemiology and prevention conference. (1998-03-19)

Mother's Promiscuity Serves Children Of The Bari
Among the Bari of Venezuela, women who are promiscuous during pregnancy increase the survivorship of the children they are carrying, but their dalliances do little for other children in the family, according to Penn State anthropologists. (1998-02-19)

Genetic Risk Factors For Anorexia Nervosa Sought
Society puts powerful pressure on women to control body weight. For this reason, some say, women suffer from anorexia nervosa -- self-starvation -- at rates 10 times higher than men. But research suggests about half the risk for the eating disorder is inherited, and the search is now on for susceptibility genes. (1998-01-19)

Strong Response To Mental Stress Could Indicate Heart Disease
An exaggerated response to mental stress could be a marker for future heart disease among people under age 60 with a strong family history of premature heart disease, according to a study by Johns Hopkins researchers. (1997-12-16)

Penn State Awarded Grant To Study Older African American Twins
The College of Health and Human Development at Penn State has been awarded a $1 million grant from the National Institute on Aging to study the health and psychosocial factors in older African American twins. (1997-11-13)

Demonstrations Work Better Than Videos At Showing Kids How To Interact
It's every parent's problem: how to get the kids to get along. Researchers at the University of Illinois report a new way to strengthen interaction. Demonstrate positive social skills. (1997-10-03)

Recidivism Rates Drop 21 Percent For Juveniles In Family Solutions Project
A program that combines first-time juvenile offenders, their parents and siblings with counselors has shown a 21 percent decrease in recidivism rates when compared with juveniles who didn't complete the program. (1997-09-18)

Nationwide Hunt For Rheumatoid Arthritis Genes Launched: National Institutes Of Health And Arthritis Foundation Announce Research Partnership
The NIH (NIAMS and NIAID) and the Arthritis Foundation are joining forces to support a national consortium of 12 research centers in the search for genes that determine susceptibility to rheumatoid arthritis. In what is the largest such effort in the world, researchers plan to collect medical information and genetic material from 1,000 families nationwide in which two or more siblings have rheumatoid arthritis. (1997-09-04)

Childhood Sibling Abuse Common, But Most Adults Don't Remember It That Way, Study Finds
If told the story of a child who was kicked, bitten, hit with a fist or choked, the words that would come into most people's mind are (1997-08-18)

Training Urged For Mothers Of Children With Cancer
Health researchers are urging special training in problem- solving skills for mothers who are raising children with cancer -- not only for themselves and the children who are ill, but to help resolve emotional and behavioral problems in their healthy children as well. (1997-08-08)

Sibling Bone Marrow Donors Do Better In School
Siblings who donate bone marrow to their brothers or sisters are more adaptive at school, their teachers tell researchers, but the children themselves aren't so sure. These same sibling-donors report more anxiety and lower self-esteem than do non-donor siblings of transplant patients. (1997-08-08)

Parents' Unequal Treatment Of Children Not Necessarily Harmful
Siblings who understand why their parents sometimes treat them unequally are much more likely to accept the differential treatment, according to research at the University of Illinois (1997-05-02)

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