Current Stents News and Events

Current Stents News and Events, Stents News Articles.
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Swimming upstream on sound waves
ETH researchers are among the first scientists to have succeeded in propelling microvehicles against a fluid flow using ultrasound. In future, these tiny vehicles are set to be introduced into the human bloodstream, thereby revolutionising the field of medicine. (2021-02-19)

Stents or bypass surgery more effective for stable patients with high-risk cardiac anatomy
A study by University of Alberta cardiologists at the Canadian VIGOUR Centre shows that a particular group of patients with stable ischemic heart disease have better outcomes with percutaneous coronary intervention (also called angioplasty with stent) or coronary artery bypass surgery and medication, versus conservative management with medication alone. (2021-02-18)

Cell-selective nanotherapy prevents post-angioplasty restenosis, promotes artery healing
A micro-RNA nanotherapy specifically inhibits the growth of cardiovascular smooth muscle cells and infiltrating inflammatory cells that form atherosclerotic plaques, while sparing endothelial cells that need to regrow to heal the injured artery. The investigational nanoparticles have the potential to achieve the therapeutic effects of drug-eluding stents without the risk of thrombosis and neoartheroclerosis, University of South Florida Health researchers report. (2021-02-10)

3D-printed bioresorbable airway stent
An ETH Zurich research team is using 3D printing to produce a new type of bioresorbable airway stent. This could greatly simplify the future treatment of upper airway obstruction. (2021-02-03)

Novel 3D printed stents deliver breakthrough treatment for oesophageal cancer
World-first 3D printed oesophageal stents developed by the University of South Australia could revolutionise the delivery of chemotherapy drugs to provide more accurate, effective and personalised treatment for patients with oesophageal cancer. (2021-02-02)

New biomaterials can be 'fine-tuned' for medical applications
Researchers in the UK and the United States have succeeded in 'fine tuning' a new thermoplastic biomaterial to enable both the rate at which it degrades in the body and its mechanical properties to be controlled independently. (2021-01-19)

Breathing easier with a better tracheal stent
New research led by the University of Pittsburgh is poised to drastically improve the use of tracheal stents for children with airway obstruction. Researchers demonstrate for the first time the successful use of a completely biodegradable magnesium-alloy tracheal stent that safely degrades and does not require removal. (2021-01-15)

No mortality increase with paclitaxel-coated devices in peripheral arterial disease
An interim analysis from the Swedish Drug-Elution Trial in Peripheral Arterial Disease (SWEDEPAD) has now been presented. It shows that, for patients with lower limb occlusive arterial disease, paclitaxel-coated balloons and stents do not bring about the rise in mortality previously reported. The study, led by the University of Gothenburg and published in The New England Journal of Medicine (NEJM), is expected to resonate internationally. (2020-12-09)

Miniscule robots of metal and plastic
Researchers at ETH Zurich have developed a technique for manufacturing micrometre-long machines by interlocking multiple materials in a complex way. Such microrobots will one day revolutionize the field of medicine. (2020-11-24)

One-month of dual anti-platelet therapy is safe and feasible after stent placement
A short, one-month treatment combining antiplatelet medication and aspirin followed by an aspirin-only regime was as effective as a 6- to 12-month course of dual treatment at preventing death, heart attacks, strokes, bleeding or the need for additional stent placement. The results of this study could lead to changes in treatment and improve patient compliance, lower costs and fewer side effects. (2020-11-16)

3D printed stents that treat inflammation
POSTECH Professor Dong-Woo Cho's research team develops bioink-loaded esophageal stents for treating radiation esophagitis. (2020-11-10)

Oncotarget: Sirolimus-eluting stents -- opposite in vitro effects on the clonogenic cell potential
The cover for issue 31 of Oncotarget features Figure 4, ''Concentration dose-response curves of sirolimus effect [55 nM-1 nM] on the number of cells per surviving colony in U2OS cell line after 2 weeks exposure,'' by Vasuri, et al. which reported that the authors evaluated the long-term effects of sirolimus on three different cell in vitro models, cultured in physiological conditions mimicking sirolimus-eluted stent, in order to clarify the effectiveness of sirolimus in blocking cell proliferation and survival. (2020-10-21)

Results from host-reduce-polytech-ACS trial reported at TCT Connect
A randomized clinical trial found that drug-eluting stents (DES) with durable polymers are non-inferior to DES with biodegradable polymers in patients with acute coronary syndrome (ACS). Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine. (2020-10-17)

Study could be first step in providing personalized care to patients with ureteral stents
Published today in Cell Reports Medicine, researchers at Lawson Health Research Institute and Western University conducted a novel microbiome study to examine bacteria associated with ureteral stents. They found that nearly all the stents, whether visibly coated or not, had unique bacterial profiles that were most associated with a patient's medical condition rather than antibiotic use. For patients with ureteral stents, they may benefit from a personalized approach to care and antibiotic treatment. (2020-09-25)

Cardiology trial shows potential benefit of genetic testing when selecting blood thinners
An international, first-of-its-kind cardiology trial used personalized genetic testing to reduce by 34 per cent the number of serious adverse events following balloon angioplasty, a treatment for the most common form of heart disease. (2020-08-25)

Clinical trial shows potential benefit to anti-platelet therapy
Heart patients who undergo percutaneous coronary intervention (PCI) or stent placement? nonsurgical procedures to improve blood flow to the heart are typically prescribed anti-platelet therapy to avoid blood clots that can lead to a heart attack or stroke. New research from the international TAILOR-PCI trial, the largest pharmacogenetics clinical trial in cardiology, suggests that genetic testing could potentially be a useful tool to help select antiplatelet medication. (2020-08-25)

Less aggressive treatment better for heart patients who go into shock
Less is sometimes more when treating heart patients who go into shock after a heart attack. (2020-08-24)

New plastic biomaterials could lead to tougher, more versatile medical implants
A new thermoplastic biomaterial, which is tough and strong but also easy to process and shape has been developed by researchers at the University of Birmingham. (2020-07-01)

DynamX Bioadaptor, a novel 'uncaging' platform for coronary artery revascularisation
Drug Eluting Stents (DES) are the mainstay of coronary artery disease treatment. Although DES design iterations have reduced MACE in the first year after PCI, beyond 1-year, a persistent 2-3% annualized event rate without plateau is observed. The DynamX™ Novolimus-Eluting Coronary Bioadaptor System is a 71 micron thin, cobalt-chromium platform with a novel ''uncaging'' mechanism of the circumferential rings after 6 months while maintaining axial links following uncaging. (2020-06-25)

Merits of revascularisation and medical treatment for chronic coronary syndromes
There are two treatment goals for patients with chronic coronary syndromes: reducing the risk of hard outcomes (i.e., death, myocardial infarction) and improving health outcomes (i.e. angina symptoms, quality of life). Several drugs address these objectives, but what about invasive interventions such as coronary angiography and revascularization? (2020-06-25)

Two paths better than one for treating patients with heart stents
Pairing a blood-thinning drug with aspirin daily for patients who have an angioplasty with a stent can contribute to better health outcomes, including lower risk of death, than aspirin alone, according to a recent study by cardiologists at the University of Alberta and Mazankowski Alberta Heart Institute. (2020-05-28)

Safety of bioabsorbable polymer against durable polymer DES in high-risk PCI patients
A novel study sought to reveal whether drug-eluting stents (DES) coated with bioabsorbable polymer (BP) presented a safety advantage without compromising efficacy compared to durable polymer (DP) formulations. Subgroup findings from the TWILIGHT trial were presented today during the SCAI 2020 Scientific Sessions Virtual Conference. (2020-05-14)

A great new way to paint 3D-printed objects
Rutgers engineers have created a highly effective way to paint complex 3D-printed objects, such as lightweight frames for aircraft and biomedical stents, that could save manufacturers time and money and provide new opportunities to create ''smart skins'' for printed parts. The findings are published in the journal ACS Applied Materials & Interfaces. (2020-04-28)

Genetic testing for antiplatelet therapy post-PCI misses cut in cardiovascular events
An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following percutaneous coronary intervention (PCI) did not meet its stated goal for cutting in half the incidence of serious adverse cardiovascular events, such as heart attack and stroke, in the year following the procedure, according to study results presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

Dropping aspirin for ticagrelor alone better in complex heart disease
The research, a subanalysis of the TWILIGHT trial, was presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

Benefit seen for ticagrelor alone, without aspirin, in patients with ACS
The research was presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

10-year data show cardiac stenting equal to CABG in preventing events
In a study with the longest follow-up to date of patients with a high-risk form of heart disease known as left main coronary artery disease (LMCAD), researchers found no significant differences in rates of death, heart attack or stroke between patients who were treated with a stent and those who underwent heart bypass surgery. The research was presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)

Surgeons successfully treat brain aneurysms using a robot
A robot was used to treat brain aneurysms for the first time. The robotic system could eventually allow remote surgery, enabling surgeons to treat strokes from afar. (2020-02-21)

Follow-up study suggests brain stents are safe and effective for reducing recurrent stroke risk
Placing stents in cholesterol-clogged brain arteries may be an option to reduce the risk of a repeat stroke. However, it is too soon to know if stenting in the brain arteries improves long-term patient outcomes. (2020-02-20)

Personalized 3D printed models in optimizing cardiac computed tomography imaging protocols
Prof. Zhonghua Sun at Curtin University, Australia, explains the novel applications of personalised 3D printed cardiovascular models for developing cardiac computed tomography (CT) imaging protocols with the goal of obtaining acceptable image quality with minimal radiation doses. (2020-02-03)

Predicting the degradation behavior of advanced medical devices
Polymer materials play a vital role in today's medicine. While many applications demand for long-lasting devices, others benefit from materials that disintegrate once their job is done. The design of such materials largely depends on the capability to predict their degradation behavior. A team of researchers at the Helmholtz-Zentrum Geesthacht led by Prof. Andreas Lendlein established a method to faster and more reliably predict the degradation of these polymer materials with sophisticated molecular architectures. (2020-01-23)

Fighting bacterial infection with drug-eluting medical devices
Medical practitioners routinely outfit patients with devices ranging from cardiovascular stents, pacemakers, catheters, and therapeutic lenses to orthopedic, breast, dental, and cochlear implants and prostheses. In an article publishing in the SIAM Journal on Applied Mathematics, Raquel Bernardes, José Ferreira, Paula de Oliveira, Mario Grassi, and Manuel Nhangumbe present a mathematical model that explores the interactions between bacterial populations, the materials they colonize, and drugs delivered from the medical devices to which they adhere. (2019-12-05)

New treatment could ease the passage of kidney stones
Researchers at MIT and Massachusetts General Hospital have devised a potential new treatment that could make passing kidney stones faster and less painful, and eliminate surgery. They identified a combination of two drugs that relax the lining of the ureter and can be delivered directly with a catheter-like instrument. (2019-12-02)

New model for predicting kidney injury after common heart procedure
A Yale-led group of doctors has developed a new mathematical model that can predict the risk of acute kidney injury (AKI) in patients undergoing a common heart procedure. (2019-11-22)

Magnets for the second dimension
ETH Zurich scientists have developed cube-shaped magnetic building blocks that can be assembled into two-dimensional shapes and controlled by an external magnetic field. They can be used for soft robotics applications. (2019-11-11)

Monitoring the corrosion of bioresorbable magnesium
ETH researchers have recently been able to monitor the corrosion of bioresorbable magnesium alloys at the nanoscale over a time scale of a few seconds to many hours. This is an important step towards accurately predicting how fast implants are resorbed by the body to enable the development of tailored materials for temporary implant applications. (2019-10-23)

Paclitaxel-coated devices are safe for unblocking arteries in lower limbs
A study in the European Heart Journal of nearly 65,000 people has shown that devices coated with a drug called paclitaxel that are used for widening blocked arteries in legs and feet are safe and not linked to an increase in deaths -- a finding that contradicts smaller studies that led to the FDA issuing a safety alert about the use of paclitaxel-coated stents and balloons for arterial revascularisation in the lower limbs in January 2019. (2019-10-08)

The Lancet journals: Papers at ESC Congress 2019
The following papers will be presented at the ESC Congress 2019, organised by the European Society of Cardiology in Paris and published simultaneously in either The Lancet or The Lancet Global Health journals. All papers are under embargo until the stated time. Contact details for corresponding authors are provided in the Articles and linked Comments. Funding information is listed on the first page of each Article. (2019-09-03)

Preventative artery repair provides major benefit after serious heart attack
The new study, a collaboration of 130 hospitals in 31 countries, has shown that opening all the blockages is better than treating only the one blockage causing the heart attack. This led to a 26% reduction in the patient's risk of dying or having a recurrent heart attack. (2019-09-01)

Stretchable wireless sensor could monitor healing of cerebral aneurysms
A wireless sensor small enough to be implanted in the blood vessels of the human brain could help clinicians evaluate the healing of aneurysms -- bulges that can cause death or serious injury if they burst. The stretchable sensor, which operates without batteries, would be wrapped around stents or diverters implanted to control blood flow in vessels affected by the aneurysms. (2019-08-28)

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