Current Steroids News and Events

Current Steroids News and Events, Steroids News Articles.
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CU Anschutz scientists reverse deadly impacts of asthma in mice
Excess mucus in the lungs can be fatal for asthma patients, but scientists at the University of Colorado Anschutz Medical Campus have broken up those secretions at the molecular level and reversed their often deadly impacts. (2021-01-13)

The meat of the matter: Environmental dissemination of beef cattle agrochemicals
A recent Point of Reference article, ''The meat of the matter: Environmental dissemination of beef cattle agrochemicals,'' published in Environmental Toxicology and Chemistry, points at synthetic chemical cocktails being emitted from cattle feed yards into the environment and how they can impact our ecosystem and our health. (2021-01-13)

Crikey! Massive prehistoric croc emerges from South East Queensland
A prehistoric croc measuring more than five meters long -- dubbed the 'swamp king' -- ruled south eastern Queensland waterways only a few million years ago. University of Queensland researchers identified the new species of prehistoric croc -- which they named Paludirex vincenti -- from fossils first unearthed in the 1980s. (2020-12-21)

Patients receiving low dose steroid at increased risk of cardiovascular disease
Glucocorticoids are steroids widely prescribed to treat a range of immune-mediated inflammatory diseases. While high doses of steroids are known to increase the risk of cardiovascular disease, the impact of lower doses is unknown. A study published in PLOS Medcine by Mar Pujades-Rodriguez at Leeds University and colleagues suggests that even low doses of glucocorticoid may increase the risk of cardiovascular diseases. (2020-12-03)

Researchers find 'missing link'
Otago researchers have found the ''missing link between stress and infertility''. (2020-12-03)

Study shows protective role sex steroids play in COVID-19
''Sex and Covid-19: A protective role for reproductive steroids,'' by Graziano Pinna, research associate professor in psychiatry, analyzes existing research to look at reasons why COVID-19 symptom severity and mortality are more frequent in men than in women and in older people. His paper suggests female reproductive steroids play a protective role. (2020-11-24)

Study reveals true origin of oldest evidence of animals
Two teams of scientists have resolved a longstanding controversy surrounding the origins of complex life on Earth. The joint studies found molecular fossils extracted from 635-million-year-old rocks aren't the earliest evidence of animals, but instead common algae. (2020-11-23)

Study: Respiratory failure in COVID-19 usually not driven by cytokine storm
A study by researchers at Washington University School of Medicine in St. Louis and St. Jude Children's Research Hospital in Memphis showed that, contrary to expectation, most people with severe COVID-19 do not suffer from unbridled inflammation. The findings suggest that anti-inflammatory therapies may not be helpful for most COVID-19 patients. (2020-11-13)

The natural artistry of disease: a wintry landscape in the eye
Researchers from Tokyo Medical and Dental University (TMDU) report a case of frosted branch angiitis in a woman presenting years after being treated for leukemia-lymphoma with allogeneic human stem cell transplant. The relevance of this ocular finding is discussed and its value as an early warning sign of immune activation following therapeutic immunological interventions is highlighted. (2020-11-09)

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments
The American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Convergence, the ACR's annual meeting. (2020-11-06)

New RA guideline emphasizes maximizing methotrexate and biologics, minimizing steroids
The American College of Rheumatology (ACR) will preview its 2020 Guideline for the Management of Rheumatoid Arthritis (RA) at ACR Convergence, the ACR's annual meeting. (2020-11-06)

Steroid inhalers/pills for asthma linked to heightened risk of brittle bones and fractures
Taking steroid inhalers or tablets to treat asthma or control flare-ups is linked to a heightened risk of brittle bones (osteoporosis) and increased vulnerability to broken bones (fragility fractures), finds research published online in the journal Thorax. (2020-10-20)

Pregnant women with severe COVID-19 face additional risks and early delivery
Pregnant women with severe or critical COVID-19 and their unborn infants face increased health risks before and after delivery but those with mild cases had similar outcomes compared to those who were uninfected, a Rutgers Robert Wood Johnson Medical School study finds. (2020-10-07)

Microwaves are useful to combine amino acids with hetero-steroids
Aza-steroids are important class of compounds because of their numerous biological activities. The hetero steroids have different hydrogen bonding ability and hydrophobicity in comparison to steroids. (2020-09-29)

Children who take steroids at increased risk for diabetes, high blood pressure, blood clots
Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers. The Rutgers study is the first to quantify these complications of oral steroids in a nationwide population of children. (2020-09-17)

Researchers identify key role of immune cells in brain infection
Researchers at the University of Liverpool have identified the specific type of immune cell that induces brain inflammation in herpes simplex virus (HSV) encephalitis. Crucially, they have also determined the signalling protein that calls this immune cell into the brain from the bloodstream. The findings, published in Cell Reports, could aid the development of targeted treatments for the brain infection, which is the most common cause of viral encephalitis worldwide. (2020-09-15)

UC study: Secondhand smoke sends more kids to the hospital
Children who are exposed to tobacco have higher rates of hospital admissions after visiting emergency departments or urgent care facilities, according to a new study by University of Cincinnati researchers. The study, set to be published in October in Pediatric Research and currently available online, found that tobacco smoke exposure also increased the risk of pediatric patients having respiratory-related procedures performed while in the emergency department, as well as medications prescribed. (2020-09-08)

Finding cortisone alternatives with fewer side effects
Many people use cortisone of a regular basis. It is used for treating rheumatism, asthma, multiple sclerosis, or even COVID-19. Steroidal medication such as cortisone is highly effective but also possesses severe side effects. Henriette Uhlenhaut, professor at Technical University of Munich (TUM), and her team are examining the beneficial effects of cortisone in order to lay the groundwork for the development of similar drugs with fewer side effects. (2020-09-02)

Corticosteroids improve survival in critically ill COVID-19 patients
In a tremendous demonstration of global collaboration, clinician-scientists have pooled data from 121 hospitals in eight countries to find that inexpensive, widely available steroids improve the odds that very sick COVID-19 patients will survive the illness. The findings were made through the ''Randomized Embedded Multifactorial Adaptive Platform-Community Acquired Pneumonia'' (REMAP-CAP) trial and are reported today in JAMA as part of a four-article package. The World Health Organization is updating its COVID-19 treatment guidance as a result. (2020-09-02)

Steroid found to improve survival of critically ill COVID-19 patients
A new international study published today [02 September] has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery. (2020-09-02)

Legal performance-enhancing substances associated with future problematic alcohol use
A new study published in the journal Pediatrics found that young adults aged 18-26 who used legal performance-enhancing substances were significantly more likely to report several problematic alcohol use and drinking-related risk behaviors seven years later. This relationship was especially strong among men. (2020-09-01)

Most adults with lupus or common types of arthritis have similar risks of getting admitted to hospital as other COVID-19 patients
Most adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to dampen their altered immune system, the cause of their disease. (2020-08-25)

Huddersfield research predicted anti-COVID steroid benefits
Huddersfield researchers publish study that found that dexamethasone could reduce death rates in hospitalized COVID-19 patients early in the pandemic. (2020-08-18)

Reducing urinary protein for patients with rare kidney disease slows kidney decline
New findings show that reducing the amount of protein in the urine of patients with focal segmental glomerulosclerosis can significantly slow declines in kidney function and extend time before patients' kidneys fail. (2020-08-10)

Immune cell steroids help tumours suppress the immune system, offering new drug targets
Tumours found to evade the immune system by telling immune cells to produce immunosuppressive steroids. Researchers discovered that immune T cells from mouse skin and breast tumours secrete steroids, and that preventing this steroid production reduced growth of tumours in mice. The study found that either removing a key steroid-producing gene, or switching it off with a drug, dramatically slowed the formation or progression of cancers, revealing potential immunotherapy drug targets. (2020-07-30)

Common blood test identifies benefits and risks of steroid treatment in COVID-19 patients
A new study led by Albert Einstein College of Medicine and Montefiore Health System (www.montefiore.org) confirms the findings of the large scale British trial of steroid use for COVID-19 patients and advances the research by answering several key questions: Which patients are most likely to benefit from steroid therapy? Could some of them be harmed? Can other formulations of steroids substitute for the agent studied in the British trial? The research was published today in the Journal of Hospital Medicine. (2020-07-22)

New CCC19 data offer insights on COVID treatments for people with cancer
Newly released data on treatment outcomes of people with cancer diagnosed with COVID-19 reveal a racial disparity in access to Remdesivir, an antiviral drug that has been shown to shorten hospital stays, and increased mortality associated with dexamethasone, a steroid that has had the opposite effect in the general patient population. (2020-07-22)

Study says inhalers ok to use amid COVID-19 concerns
University of Huddersfield researchers find that the benefits of inhalers for asthma sufferers outweigh the risks of contracting coronavirus, following concerns raised after WHO warned that steroids could reduce immunity. (2020-07-09)

Asthma does not seem to increase the severity of COVID-19
Asthma does not appear to increase the risk for a person contracting COVID-19 or influence its severity, according to a team of Rutgers researchers. (2020-07-06)

In mouse study, black raspberries show promise for reducing skin inflammation
In a study done with mice and published earlier this month in the journal Nutrients, researchers found that a diet high in black raspberries reduced inflammation from contact hypersensitivity -- a condition that causes redness and inflammation in the skin. (2020-07-02)

New compounds from starfish of Kuril basin show efficacy against cancer cells.
Russian scientists from Far Eastern Federal University (FEFU), G. B. Elyakov Pacific Institute of Bioorganic Chemistry (PIBOC FEB RAS), and A.V. Zhirmunsky National Scientific Center for Marine Biology (NSCMB FEB RAS) have discovered four new steroid substances which target cells of human breast cancer, and colorectal carcinoma. They were extracted from the starfish Ceramaster patagonicus, a Kuril basin seabed dweller. A related article appears in Marine Drugs. (2020-06-26)

Immunotherapy, steroids had positive outcomes in children with COVID-related multi-system inflammatory syndrome
Treatment with antibodies purified from donated blood -- immune globulin therapy -- and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association. (2020-05-19)

Machine that oxygenates blood may help critically ill COVID-19 patients, according to WVU study
Sometimes the lung function of COVID-19 patients deteriorates so much that even ventilators can't save them. In that case, extracorporeal membrane oxygenation machines may keep them oxygenated enough to survive. New research out of WVU provides insight into which COVID-19 patients tend to fare better on ECMO than others. (2020-05-18)

A review on phytochemistry, pharmacological action, ethanobotanical uses and nutritional potential
This comprehensive review presented by researchers from K.S. Rangasamy College of Arts and Science, Tiruchengode, Tamil-Nadu, India, gives readers a brief overview of phytoconstituents, nutritional values and medicinal properties of the plant. (2020-05-07)

Study helps to identify medications which are safe to use in treatment of COVID-19
A recent study has found that there is no evidence for or against the use of non-steroidal anti-inflammatory drugs such as ibuprofen for patients with COVID-19. (2020-03-30)

Cumulative doses of oral steroids linked to increased blood pressure
Cumulative doses of oral steroids in patients with chronic inflammatory diseases are associated with increased hypertension (blood pressure) for those who take them regularly, found new research in CMAJ (Canadian Medical Association Journal). (2020-03-23)

Access to forbidden rings
Chemists (UNIGE) have now devised a new technique for creating chains of molecular rings that do not use standard chemical interactions but contact with large molecular surfaces that are electron-poor and do not exist in nature. Unlike with standard procedures, this new technique works by autocatalysis - the rarest, but also the most ambitious, type of transformation that exists in chemistry. The results open up new prospects for molecular cyclization. (2020-03-18)

St. Jude finds cancer drug resistance genes and possibly how to limit their effects
Drug resistance is a leading cause of cancer death in children and adults with leukemia. St. Jude Children's Research Hospital scientists have developed a novel strategy to find the genes responsible. (2020-03-09)

Revving up immune system may help treat eczema
Studying eczema, researchers at Washington University School of Medicine in St. Louis have found that boosting the number of natural killer cells in the blood is a possible treatment strategy for the skin condition and also may help with related health problems, such as asthma. (2020-02-26)

Diabetes drug reduces complications of long-term steroid therapy
A drug used to treat type 2 diabetes could offer a simple and cheap solution to reduce dangerous side effects of steroid treatment, new research from Queen Mary University of London suggests. (2020-02-25)

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