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Time for co-ordinated action on alcohol
This week's editorial discusses the current approaches in tackling the public-health impact of excessive alcohol consumption (especially in the UK), and concludes that enhanced awareness and training of primary-care professionals will be vital in managing future alcohol problems. (2004-03-25)

2005 global tuberculosis targets may be out of reach
An article in this week's issue of THE LANCET cautions that key targets for tuberculosis control-due to be reached by next year-are unlikely to be met unless renewed strategic action and financial support can be secured. (2004-03-04)

Targeted antiviral prophylaxis of flu case contacts could successfully contain pandemic influenza
In a future outbreak of pandemic influenza, supplies of flu vaccine might not be available quickly enough to contain the spread of disease. However, many thousands of deaths could be prevented if antiviral agents were given to the close contacts of those with suspected cases of flu until adequate supplies of vaccine could be manufactured and distributed. (2004-03-01)

Gene therapy for a broken heart
Gene therapy represents a potential strategy for the treatment of cardiac dysfunction. In the March 1 issue of the JCI, John Ross, Jr., and colleagues from the University of California, San Diego, report that gene delivery to express a modified form of the phospholamban protein, S16EPLN, to chronically failing rat hearts after a heart attack exerted beneficial effects, suggesting that S16EPLN gene delivery is a promising novel strategy for the treatment of chronic heart failure. (2004-03-01)

Medically supervised injecting centres should be piloted in the UK
A programme of medically supervised injecting centres should be piloted in the UK, as part of an integrated public health strategy, say the authors of an article in this week's BMJ. (2004-01-08)

Gastrointestinal specialists comment on new study on 'Virtual' colonoscopy
The American College of Gastroenterology congratulates the investigators of a new study on virtual colonoscopy that will appear in the New England Journal of Medicine next week, including Douglas K. Rex, M.D., FACG, President of the American College of Gastroenterology and Director of Endoscopy at Indiana University Hospital in Indianapolis, IN. New colorectal cancer screening strategies, including virtual colonoscopy and fecal DNA testing, offer the potential to enhance the acceptability of colorectal cancer screening to some persons. (2003-12-01)

Sun avoidance will not reduce cancer
Avoiding the sun is not the best strategy for reducing overall rates of cancer, claims a senior doctor in a letter to this week's BMJ. Recommending moderate exposure to the sun would be more prudent. (2003-11-20)

Fast-acting ebola vaccine protects monkeys
A single shot of a fast-acting, experimental Ebola vaccine successfully protects monkeys from the deadly virus after only one month. If this vaccine proves similarly effective in humans, it may one day allow scientists to quickly contain Ebola outbreaks with ring vaccination--the same strategy successfully used in the past against smallpox, according to a study published in this week's issue of Nature. (2003-08-06)

AAS praises President's Commission for emphasizing suicide prevention
The American Association of Suicidology praised today the release of the Report of the President's New Freedom Commission on Mental Health. The report, entitled Achieving the Promise: Transforming Mental Health Care in America, makes as its first recommendation to (2003-07-24)

New radiotherapy strategy improves survival for lung cancer patients
According to findings presented at the annual meeting of the American Society of Clinical Oncology, a new therapeutic radiation strategy for non-small cell lung cancer leads to improved survival for patients with locally advanced disease. The results, presented by Chandra Belani, M.D., co-director of the Lung Cancer Program at the University of Pittsburgh Cancer Institute, found that hyperfractionated accelerated radiotherapy (HART) is an effective and well-tolerated treatment strategy when compared to standard thoracic radiotherapy. (2003-06-01)

Threading instruction improves weak children's arithmetic
Dutch research has revealed that pupils at special schools for primary education can best learn arithmetic using one specific strategy. When adding and subtracting with numbers less than 100, these pupils make least mistakes when using the so-called threading strategy (for example, 65 - 23 = 65 - 20-3). (2003-04-11)

Researchers achieve germline transmission of 'gene knockdown' in mice
RNA interference (RNAi) has emerged as a powerful tool in biomedical research. A new study published in the February issue of Nature Structural Biology reports the creation of transgenic mice in which inherited RNAi lowers or silences the expression of a target gene, producing a stable (2003-01-19)

Slowing insect resistance to genetically modified crops
Genetically modified Bt crops are now widely used in the USA. These crops contain genes from bacteria that make them toxic to some insect pests. A central concern in regulating these genetically modified crops is the risk of insects evolving resistance to the Bt toxins. To reduce this risk, the (2002-10-30)

Early intervention could halve angina rate for people at moderate risk of heart attack
Authors of a UK study published on THE LANCET's website today, Sunday 1 September, (2002-08-31)

Long-term interruption of HIV treatment may be safe in certain patients
Interrupting anti-HIV treatment for an extended period and then re-initiating therapy might be safe in some patients and may be an important HIV treatment strategy for the reduction of long-term toxicity, medication burden and expense, a Northwestern University study found. (2002-07-10)

Wanted: A coherent strategy on asylum seekers
New research has revealed a lack of coordination among the various bodies dealing with asylum seekers in Britain. (2002-06-07)

Screening families with a history of high cholesterol is most cost effective way to cut heart deaths
Screening relatives of people with high cholesterol levels is the most cost effective way to reduce deaths from coronary heart disease, yet no recommended screening strategy currently exists in the United Kingdom , according to researchers in this week's BMJ. (2002-05-30)

Estrogen may dictate what problem-solving strategy brain uses
Deciding on hormone-replacement therapy - weighing the far-reaching benefits and risks - can give a woman a headache. Now researchers say estrogen may dictate what problem-solving strategies the brain uses to solve problems. (2002-05-15)

Inhibiting cardiac protein through gene therapy improves human heart cell function
Blocking a key protein involved in calcium regulation can improve the function of failing heart cells, according to a study in the February 26 issue of Circulation. The work holds promise for treating congestive heart failure. (2002-02-25)

The stongest game show strategy
Players competing on the game show The Weakest Link would be better off banking its winnings either after each question or after a run of six successive right answers. An American mathematician says that players often lose their nerve and bank after three questions - even though it isn't the best strategy. (2002-01-16)

Adaptive-decision strategy offsets uncertainties in climate sensitivity
The uncertainty of climate change because of global warming is much greater than previously thought, and as a result, policy-makers should adopt a robust, adaptive-decision strategy to cope with potential consequences, researchers at the University of Illinois say. (2001-09-28)

Postraumatic vaccination for spinal cord injury
Here Hauben and coworkers explore a remarkable strategy by which animals may be vaccinated against the effects of spinal cord injury. While vaccination could hardly be expected to prevent a physical trauma, the authors note that much of the tissue destruction and nerve death that leads to paralysis following mild trauma to the spine occurs a week or more after injury and is mediated by immune cells. (2001-08-15)

Invasive versus conservative coronary procedures: Invasive had better outcomes, costs were similar
Emory University researchers studied data related to two approaches to acute coronary syndromes to determine which was most cost effective for cardiac patients. After six months, Emory researchers determined that patients treated with an invasive approach had better outcomes, however, at six months, because the follow-up costs were higher in the conservatively treated patients, there was no difference in overall cost between the procedures. (2001-03-20)

Hutchinson Center receives $1.2 million from National Science Foundation to study plant genetics
The Fred Hutchinson Cancer Research Center has received a $1.2 million first-year grant from the National Science Foundation to implement a new strategy for obtaining plants with desirable genetic muations -- without transgenic manipulation. (2000-09-20)

New study suggests prostate screening should be done earlier, every two years
Although medical scientists still debate the effectiveness of prostate cancer screening known as serum prostate-specific antigen testing and even of prostate cancer treatments themselves, the PSA procedure is performed widely to detect the deadly illness earlier. A new study conducted at the University of North Carolina at Chapel Hill suggests that current PSA screening strategies should be changed. (2000-09-18)

Carnegie Mellon brain scientists find human brain applies law of least effort when solving problems
Using brain imaging, scientists at Carnegie Mellon University have discovered how the human brain goes to work on solving a problem and how it employs surprising economies of effort in the process. The results appear in the June issue of Cognitive Psychology. (2000-06-19)

Potato extract: A new direction for antibiotics
A potato extract may offer us insight into a new strategy for antibiotic research: Don't kill the bacteria, just prevent them from attaching to our cells. Researchers from the Miami University of Ohio report the results of their study on this potato extract at the 100th General Meeting of the American Society for Microbiology. (2000-05-21)

'Unprecedented' tobacco industry campaign undermined report on second-hand smoke and cancer, researchers said
A ten-year study conducted by the International Agency for Research in Cancer (IARC) examining the links between second- hand smoke and cancer was subverted by an unprecedented misinformation campaign coordinated by the tobacco industry and resulting in misleading media reports of the European scientific study even before it was published. (2000-04-05)

Learning by example works best when model is an individual of social stature
Do celebrity endorsements influence how people make decisions? Advertisers who pay big bucks for celebrity endorsements seem to think so. And now an innovative economics research project has demonstrated that most people will follow the example of a successful (2000-02-20)

New Strategy May Succeed At Extending The Life Of Transplanted Kidneys
A kidney transplant offers people with kidney failure a new chance at a normal, active life. But, on average, a transplanted kidney continues to function for only nine years. Now, doctors at the University of Maryland Medical Center say a new strategy to extend the function of transplanted kidneys shows promise. (1999-05-16)

NSB Meets In L.A. On Expanded Environmental Research, Education, Assessment
The National Science Board (NSB) meeting at the Getty Center in Los Angeles, February 17-18, will feature a symposium on the National Science Foundation's (NSF) role in environmental research, education and assessment. (1999-02-09)

Health Experts Call For Increase In Cigarette Taxes
Ontario's cheap cigarettes undermine a provincial strategy to control the smoking epidemic, says a report from the Ontario Tobacco Research Unit. (1998-11-24)

Paper Wasp Queens Wait To Hijack Or Adopt
A Cornell researcher has found that certain female paper wasps (Polistes dominulus) (1998-08-07)

Pop(ulation) Culture: Aggressive Cholesterol-Lowering Strategy = Fewer Heart Attacks
DALLAS, March 24 -- By lowering blood cholesterol levels by just 10 percent in a population, the result could be a 20 percent reduction in heart attack deaths suggest authors of a study published in today's Circulation: Journal of the American Heart Association. (1998-03-23)

Just How Heavy Is Cigarette Smoking's Toll On Non-Smokers?
Just how heavy is cigarette smoking's toll on non-smokers? A new (1998-03-19)

Scientists Invent Faster Gene Function Identification System
Researchers at Ohio University have invented a new way to identify gene function in a matter of days, a discovery that could step up the development of cures and treatments for genetic illnesses. The method may be an improvement over conventional identification techniques, which can take months to years. (1998-02-23)

Adjusting To Climate Shift Better Than Following Typically Advocated Plans
In the face of global warming, the best strategy may be to keep a cool head and learn to adapt, says a researcher at the University of Illinois. (1997-05-02)

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