Current Thyroid News and Events

Current Thyroid News and Events, Thyroid News Articles.
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Study links exposure to nighttime artificial lights with elevated thyroid cancer risk
People living in regions with high levels of outdoor artificial light at night may face a higher risk of developing thyroid cancer. The finding comes from a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. (2021-02-08)

New computational tool reliably differentiates between cancer and normal cells from single-cell RNA-sequencing data
MD Anderson researchers have developed a new computational tool to accurately differentiate between cancer cells and normal cells when analyzing large single-cell RNA-sequencing data. (2021-01-18)

Singing a tumor test song
Singing may be the next-generation, noninvasive approach to determining the health of a patient's thyroid. When a person sings, the vibrations create waves in the tissue near the vocal tract called shear waves. If a tumor is present in the thyroid, the elasticity of its surrounding tissue increases, stiffening, and causing the shear waves to accelerate. Using ultrasound imaging to measure these waves, researchers can determine the elasticity of the thyroid tissue. (2021-01-12)

In-utero exposures associated with increased risk of thyroid cancer
A recent study shows that thyroid cancer is related to in-utero exposures. (2021-01-05)

Study shows that active surveillance holds promise as a treatment option for low-risk thyroid cancer
Results from a new study co-led by researchers at Dartmouth's Geisel School of Medicine and the Department of Surgery at Kuma Hospital in Kobe, Japan, show that active surveillance can be successfully implemented as a viable treatment option for patients with low-risk thyroid cancer. (2020-12-07)

Cancer cases are rising in adolescents and young adults
Cancer cases in adolescents and young adults have risen by 30% during the last four decades, with kidney cancer rising at the greatest rate, according to researchers at Penn State College of Medicine. The team said further research into screening, diagnosis and treatment are needed to address the growing trend in this age group. (2020-12-01)

How thyroid function affects stress-related heart problems
Chest pain, shortness of breath, heart flutter and palpitations: these symptoms are not only characteristic of a heart attack, but can also be caused by another, as yet little researched condition. So-called Takotsubo cardiomyopathy is a rare but life-threatening disease of the heart that can occur during extreme stress events. Heart and hormone research teams in Bochum and Mannheim have now shown that there is apparently a strong link between the occurrence of Takotsubo syndrome and impaired thyroid function in patients. (2020-12-01)

Born to be young?
The environment we experience in early-life is known to have major consequences on later-life health and lifespan. A new study led from the University of Turku in Finland using an avian model suggests that increased prenatal exposure to maternal thyroid hormones could have beneficial effects on the 'biological age' at birth. (2020-11-11)

Induced liver regeneration enhances CRISPR/Cas9-mediated gene repair
Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver. This dietary induction of hepatocyte regeneration may be a viable clinical strategy to enhance gene repair in the liver. (2020-11-10)

New cancer drugs saved over 1.2 million people in the US over 16 years, new study shows
More than 1.2 million people in the US prevented facing death following a cancer diagnosis, between the year 2000 and 2016, thanks to ever improving treatment options -- a large new national study shows. (2020-11-09)

Reduced hormone supply in pregnant mothers linked to ADHD in their children
Low levels of key, body-regulating chemicals in mothers during the first three months of pregnancy may interfere with the baby's brain development, a large American study shows. (2020-10-21)

New method allows more targeted measurement of thyroid hormone action in tissue
A team led by Michael Krebs from MedUni Vienna's Division of Endocrinology and Metabolism has now conducted a study to test the use of magnetic resonance spectroscopy (NMRS) to measure the effect in body tissue as well. They were able to identify certain phosphorus-containing compounds that are visible in NMRS as markers for thyroid hormone action in tissue. The study has been published in the prestigious ''Journal of Clinical Endocrinology and Metabolism''. (2020-10-20)

Clinical trial of selpercatinib shows strong response for patients with non-small cell lung cancer
Drug shown to precisely target non-small cell lung cancer driven by mutations to gene RET. Majority of patients on trial experience shrinking tumours and live for more than a year without disease progression. National Cancer Centre Singapore, one of a handful of three Asian centres to participate in the trial, has implemented routine testing of the gene RET for all lung cancer patients. Findings published in high impact factor journal, New England Journal of Medicine. (2020-09-28)

Exercise hormone may modulate genes associated with replication of novel coronavirus
Brazilian researchers observed that in uninfected adipocytes, the hormone irisin altered the expression of genes that regulate ACE-2, which encodes a protein to which the virus binds in order to invade human cells. (2020-09-22)

New study estimates nearly 90,000 cancer cases diagnosed in adolescents and young adults
A new report examining cancer in adolescents and young adults (AYAs), defined as diagnoses occurring during ages 15 to 39, provides updated estimates of the contemporary cancer burden in this age group, predicting that 89,500 cases and 9,270 deaths will occur in 2020 in the United States. (2020-09-17)

Study: Synthetic medication and desiccated thyroid equally effective to treat hypothyroidism
A study by researchers at Kaiser Permanente in Denver, Colorado evaluated the stability of thyroid stimulating hormone (TSH) in patients using synthetic medication versus those using desiccated thyroid products to treat hypothyroidism. The results showed no difference in TSH stability over a three-year period between patients taking desiccated thyroid products and those on synthetic levothyroxine, an unanticipated finding given concerns about variability among batches of desiccated thyroid, which is prescribed much less frequently than synthetic levothyroxine. (2020-09-15)

Detection of PCBs and their metabolites (OH-PCBs) in the fetal brain of a Japanese macaque
This study selected the Japanese macaque (Macaca fuscata) as a model animal for the fetal transfer of OH-PCBs in humans, and revealed OH-PCB concentrations and their relationships in the maternal and fetal brains. The key finding from this study is that OH-PCBs can reach the developing brain of the fetus as early as the first trimester of pregnancy. These OH-PCBs may exceed the levels that induce adverse effects on neurodevelopment. (2020-09-14)

Possible genetic link found between hypothyroidism and development of canine T-zone lymphoma
A genetic mutation might be the reason dogs with hypothyroidism are less likely to develop T-zone lymphoma (TZL). That's the finding from Morris Animal Foundation-funded researchers at Colorado State University who tried to identify genetic risk factors for TZL using a genome-wide association study (GWAS) and subsequent targeted sequencing. They recently published their results in the journal BMC Genomics. (2020-09-14)

Thyroid inflammation linked to anxiety disorders
Patients with autoimmune inflammation of their thyroid may be at greater risk of developing anxiety, according to a study being presented at e-ECE 2020. The study found that people with anxiety may also have inflammation in their thyroid gland that can be reduced by taking the non-steroidal anti-inflammatory, ibuprofen. These findings suggest that thyroid function may play an important role in the development of anxiety disorders. (2020-09-06)

Strong, durable responses to selpercatinib in RET-driven medullary thyroid cancer
Selpercatinib (Retevmo), a drug targeted precisely against cancers driven by mutations or alterations in the gene RET, was effective in a clinical trial at shrinking tumors in patients with medullary thyroid cancer. (2020-08-26)

Lung cancer trial of RET inhibitor selpercatinib achieves durable responses in majority of patients with RET gene fusions
For patients with non-small cell lung cancers marked by RET gene fusions, the targeted therapy selpercatinib was well tolerated and achieved durable objective responses, or tumor shrinkage, in the majority of patients in a Phase I/II trial. (2020-08-26)

Research story tip: Down syndrome mice open door to better understanding of the disorder
Johns Hopkins Medicine researchers and their collaborators have created and characterized a new mouse replica of Down syndrome, long considered one of the most challenging disorders to simulate in laboratory animals. (2020-08-18)

Study finds cancer mapping may solve puzzle of regional disease links
New statistical analysis finds cancer mapping may help question regional disease links. (2020-08-13)

Some physicians are ordering thyroid tests for unsupported reasons
Up to one-third of physicians reported sending patients for a thyroid ultrasound for reasons not supported by clinical care guidelines, a new study led by University of Michigan Rogel Cancer Center researchers finds. Routine use of ultrasounds to detect cancerous thyroid nodules have led to a significant increase in thyroid cancer cases in recent years, although many are low-risk and unlikely to cause serious harm. (2020-08-12)

Comparing hyperthyroidism treatments with risk of cancer death
Researchers compared long-term risk of death from a solid cancer in patients treated with radioactive iodine, anti-thyroid drugs or surgery for hyperthyroidism. (2020-07-23)

Levothyroxine doesn't improve cardiac function for heart attack patients
Tens of thousands of patients with underactive thyroid are being prescribed Levothyroxine after a heart attack - but the results a of a double-blind randomised clinical trial has shown that it offers no benefits to their heart function. The researchers, led by Dr Salman Razvi at Newcastle University, UK, are now working to change the international guidelines on treatment. (2020-07-21)

Widely used blood test could advance heart failure treatment
Researchers at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) and FuWai Heart Hospital (Beijing, China) have developed a new use for a common blood test, which could provide a potentially life-saving treatment for heart failure. (2020-07-16)

New method estimates risks of hormone-disrupting substances in drinking water
Researchers at Karolinska Institutet in Sweden have developed a new method that can make it easier for public authorities to assess the health risks of hormone-disrupting chemicals in the environment. The study, which is published in Environmental Health Perspectives, shows that women are particularly at risk of decreased levels of thyroid hormones related to PFAS-contaminated drinking water. (2020-07-08)

Iodine exposure in the NICU may lead to decrease in thyroid function, NIH study suggests
Exposure to iodine used for medical procedures in a neonatal intensive care unit (NICU) may increase an infant's risk for congenital hypothyroidism (loss of thyroid function), suggests a study by researchers at the National Institutes of Health and other institutions. (2020-07-07)

Trends in the global burden of thyroid cancer
This study examined the worldwide trends of thyroid cancer from 1990 to 2017 according to geographic location, sex, age and socioeconomic factors. (2020-06-26)

Mild thyroid dysfunction affects one in five women with a history of miscarriage or subfertility
Mild thyroid abnormalities affect up to one in five women with a history of miscarriage or subfertility which is a prolonged time span of trying to become pregnant, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2020-06-17)

Something in the water: Environmental pollutant may be more hazardous than previously thought
Sometimes toxins, such as hazardous wastes and industrial byproducts, seep into groundwater, the source of our drinking water. One such pollutant is perchlorate, a chemical compound used in rocket fuels, fireworks, fertilizers and other materials. The compound is thought to contribute to health issues in humans such as hypothyroidism, the decreased production of hormones from the thyroid gland, which can impact development. (2020-06-05)

Something in the water: Pollutant may be more hazardous than previously thought
Perchlorate, a chemical compound used in rocket fuels and other materials, may be a more hazardous pollutant than previously thought, says a new study from Johns Hopkins Medicine. (2020-06-05)

Thyroid dysfunction in pregnancy being overdiagnosed, overtreated
The current practice of testing most pregnant women for thyroid stimulating hormone (TSH) may be leading to overdiagnosis and overtreatment, according to new research in CMAJ (Canadian Medical Association Journal). http://www.cmaj.ca/lookup/doi/10.1503/cmaj.191664 (2020-06-01)

Targeted therapy pralsetinib achieves high response rates in advanced cancers with RET gene fusions
The targeted therapy pralsetinib appears to have high response rates and durable activity in patients with a broad variety of tumors harboring RET gene fusions, according to results from the international Phase I/II ARROW trial, led by researchers at The University of Texas MD Anderson Cancer Center. (2020-05-29)

Patients with COVID-19 may develop thyroid infection
COVID-19 infection may cause subacute thyroiditis, according to a new case study published in The Journal of Clinical Endocrinology & Metabolism. (2020-05-21)

Exposure to air pollution during pregnancy is associated with growth delays
A new study by the Barcelona Institute for Global Health (ISGlobal) has found an association between exposure to air pollution during pregnancy and delays in physical growth in the early years after birth. (2020-04-22)

Examining rates of thyroid cancer among World Trade Center rescue/recovery workers
Rates and methods of detection of thyroid cancer diagnosed in male rescue/recovery workers at the World Trade Center site after the 9/11 terrorist attacks were compared with demographically similar individuals from Olmsted County, Minnesota, to see if increased rates of thyroid cancer among those workers were associated with the identification of asymptomatic cancers detected during heightened nonthyroid-related medical surveillance. (2020-04-20)

Thyroid hormone use may raise death risk in older adults
Thyroid hormone replacement therapy in older adults is associated with a higher risk of death compared with no treatment, a large study finds. The study results were accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society. (2020-03-31)

Underactive thyroid more common in people working long hours
Adults who work long hours are more likely to have hypothyroidism, which is an underactive thyroid, according to study results accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society. (2020-03-31)

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