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Current Transplantation News and Events, Transplantation News Articles.
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Landmark 30-year study on Crigler-Najjar syndrome underscores the need for new therapies
A new study summarizes more than 30 years of clinical experience and describes the clinical course of 28 individuals homozygous for damaging mutations in the UGT1A1 gene who were born between 1984 and 2015 with Crigler-Najjar syndrome. (2020-04-16)
Researchers restore sight in mice by turning skin cells into light-sensing eye cells
Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision, sidestepping the need for stem cells. (2020-04-15)
Researchers successfully repair stroke-damaged rat brains
Researchers at Lund University in Sweden have succeeded in restoring mobility and sensation of touch in stroke-afflicted rats by reprogramming human skin cells to become nerve cells, which were then transplanted into the rats' brains. (2020-04-08)
New 'more effective' stem cell transplant method could aid blood cancer patients
Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults. (2020-03-26)
For clogged and hardened hearts, a mussel is the solution
Prof. Hyung Joon Cha and his research team developed a stem cell therapy on myocardial infarction, using proteins that can be found in mussels, mussel adhesive proteins. (2020-03-25)
Distance to transplant center and likelihood of being considered for transplantation
In an analysis of information on adults who began treatment for kidney failure at any Georgia, North Carolina, or South Carolina dialysis facility, the distance from a patient's residence to the nearest transplant center did not appear to affect the likelihood of transplant-related referrals and evaluations. (2020-03-24)
UCI team demonstrates ability to supercharge cells with mitochondrial transplantation
UCI researchers have shown that they can give cells a short-term boost of energy through mitochondrial transplantation. (2020-03-23)
Early blood marker may predict future risk of kidney transplant failure
In a study of kidney transplant recipients, the composition of certain immune cells in the blood 1 year after kidney transplantation was linked with a patient's subsequent risk of kidney transplant failure. (2020-03-12)
PET imaging offers new insights into post-transplant care for heart patients
Myocardial blood flow (MBF) and myocardial flow reserve (MFR) have been identified as accurate indicators for graft failure after cardiac transplantation, according to research published in The Journal of Nuclear Medicine. (2020-03-05)
Study reveals improving survival rates after liver transplantation in the UK
In the past two decades, death rates after liver transplantation have dropped by more than half in the UK, according to a recent analysis of almost 10,000 liver transplant recipients published in BJS (British Journal of Surgery). (2020-03-04)
Mount Sinai researchers discover new approach for use of stem cells to improve bone marrow transplantation
Mount Sinai researchers have discovered a way to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation, according to a study published on Feb. (2020-02-27)
Elderly patients also benefit from kidney transplantation
So far, kidney transplantation has generally not been offered to elderly patients (>75 years) because of the perioperative risks. (2020-02-26)
New tool aids patients in selecting a transplant center
A new website developed by researchers at Hennepin Healthcare Research Institute (HHRI) and the University of Minnesota (UMN) is making it easier for organ transplant candidates to choose which transplant center is right for them. (2020-02-24)
First Swedish transplant of uterus from deceased donor
The Swedish team responsible for uterine transplantation research has, for the first time, transplanted a uterus from a deceased donor. (2020-02-17)
Kidney patients benefit using organs from Hepatitis C-infected donors
Kidney patients benefit by accepting kidneys from donors with hepatitis C, according to a University of Cincinnati physician-researcher. (2020-02-17)
UC research could help reduce disease incidence in organ donors
Researchers at the University of Cincinnati are among the first to adopt genotyping that helps identify and predict the risk accompanying individuals wishing to donate a kidney. (2020-02-11)
City of Hope's Triplex vaccine reduces rate of CMV complications in transplant recipients
Patients who underwent a stem cell transplant and received the Triplex vaccine to prevent a type of herpes virus -- cytomegalovirus (CMV) -- from duplicating out of control were 50% less likely to develop health complications related to the virus than patients who did not take Triplex, according to a City of Hope-led study published today in Annals of Internal Medicine. (2020-02-10)
The economic burden of kidney transplant failure in the United States
A recent analysis published in the American Journal of Transplantation estimates that for the average US patient who has undergone kidney transplantation, failure of the transplanted organ (graft failure) will impose additional medical costs of $78,079 and a loss of 1.66 quality-adjusted life years. (2020-02-05)
Virtual crossmatching improves quality of life for kidney transplant patients
Virtual antibody crossmatching is a safe and efficient way of selecting kidney transplant recipients. (2020-01-31)
30-year study identifies need of disease-modifying therapies for maple syrup urine disease
A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders. (2020-01-24)
Subtle structural features in donated kidneys may predict risk of transplant failure
Mayo Clinic researchers have discovered that subtle structural features in kidneys from living donors that can only be seen with a microscope may predict the risk of transplant failure in recipients. (2020-01-23)
Certain liver cells may help prevent organ rejection after transplant, study finds
Mesenchymal stromal cells from fat tissue and bone marrow are widely used in therapeutic trials for their anti-inflammatory qualities, but new Mayo Clinic research finds that liver cells may be of greater value. (2020-01-21)
Machine keeps human livers alive for one week outside of the body
Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keeps them alive outside the body for one week. (2020-01-13)
New research may lead to increased use of available hearts for transplant
A new study provides hope that the number of children dying on the transplantation list while waiting for a new heart could potentially be reduced dramatically. (2020-01-06)
Radical treatment of chronic oral infection before stem cell transplantation not necessary
A recently published study indicates that oral infections seem to have no association with the risk of stem cell transplantation patients dying of or getting a serious infection within six months of the procedure. (2020-01-03)
Making blood on demand: How far have we come?
The authors conclude the review with a summary of future perspectives, in which they discuss how newly developed techniques, like the deactivated-Cas9 (dCas9) gene-expression control system, can be utilized during the course of hematopoietic differentiation of pluripotent stem cells for precise temporal control of the aforementioned master regulators to achieve functional HSCs. (2019-12-31)
Delivery of healthy donor cells key to correcting bone disorder, UConn researchers find
n the journal STEM CELLS, research group of Dr. Ivo Kalajzic, lead investigator and professor, presents a study with potential for new treatments to address the root cause of weak and brittle bones. (2019-12-23)
UTHealth's Cynthia Ju awarded NIH grants for liver injury research
Tiny solutions are being sought for big liver problems by a scientist at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth). (2019-12-20)
Hepatitis C-positive donors a viable option to expand heart donor pool
Patients who were transplanted with hearts from hepatitis C-positive donors had comparable outcomes after one year to patients who received hearts from donors that didn't have the disease, according to a Vanderbilt University Medical Center study published in JAMA Cardiology. (2019-12-20)
Air pollution may increase mortality risk after heart transplant
Heart transplant recipients who live in areas where particulate matter (PM2.5) air pollution levels reached above national limits for clean air had a 26% higher risk of mortality due to infection, according to a study published today in the Journal of the American College of Cardiology. (2019-12-09)
New research finds signal of decreased early post transplant survival in new heart transplant system
In an analysis of the new heart organ allocation system for transplant patients in the US, researchers have identified a signal of a decrease in heart transplant survival rates. (2019-11-21)
Robotic transplants safe for kidney disease patients with obesity
Researchers report that among patients with obesity, robotic kidney transplants produce survival outcomes comparable to those seen among nonobese patients. (2019-11-19)
Study: Multidisciplinary transplantation evaluation shows promise for older adults
Older adults with blood cancers can benefit from a team-based, holistic evaluation before undergoing transplantation, according to a new study published today in Blood Advances. (2019-11-14)
University of Cincinnati finds new option for liver transplant patients
Budesonide, a drug commonly used to treat Crohn's Disease, may offer fewer side effects and work at least as well as prednisone as an anti-organ rejection medication in liver transplant patients. (2019-11-08)
'Super-grafts' that could treat diabetes
To save patients with a severe form of type 1 diabetes, pancreatic cell transplantation is the last resort. (2019-11-06)
Cleveland clinic's first purely laparoscopic living donor surgery for liver transplant
Cleveland Clinic has successfully performed the Midwest's first purely laparoscopic living donor surgery for liver transplantation in an adult recipient. (2019-10-30)
Study examines variation in transplant centers' use of less-than-ideal organs
In 2010-2016, many US transplant centers commonly accepted deceased donor kidneys with less desirable characteristics. (2019-10-17)
Viagra helps mobilize bone marrow stem cells for transplantation in mice
The combination of two clinically approved drugs -- Viagra and Plerixafor -- rapidly and efficiently mobilizes blood stem cells from the bone marrow into the bloodstream in mice, researchers report Oct. (2019-10-10)
Treatment for 'low T' could someday come from a single skin cell, USC research shows
USC researchers have successfully grown human, testosterone-producing cells in the lab, paving the way to someday treat low testosterone with personalized replacement cells. (2019-10-07)
Mounting brain organoid research reignites ethical debate
As research involving the transplantation of human 'mini-brains' -- known as brain organoids -- into animals to study disease continues to expand, so do the ethical debates around the practice. (2019-10-03)
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