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Current Tumors News and Events, Tumors News Articles.
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Heat and irradiation: New approach for more selectively fighting tumors
Researchers wish to treat tumors more effectively in the future by combining radiation therapy and focused ultrasound. The joint project SONO-RAY began on Oct. 1, 2016. The project is part of Leipzig University's Innovation Center for Computer-Assisted Surgery as well as OncoRay -- National Center for Radiation Research in Oncology, located in Dresden. Approximately €6 million have been granted by the German Federal Ministry of Education and Research to fund the project. (2016-10-17)

OU researchers develop novel, non-invasive cancer therapy
A staggering 1.7 million persons in the United States will be diagnosed with cancer in 2016, with 600,000 cases ending in death. University of Oklahoma researchers have collaborated to design a novel, non-invasive cancer therapy that could eliminate tumors without affecting the healthy cells in the body. (2016-10-17)

Long-term experience supports efficacy and safety of PRRT for treating neuroendocrine tumors
More than 10 years of published clinical data and personal experience using PRRT-based targeted therapy of neuroendocrine tumors supports the effectiveness of this novel treatment approach and the ability to minimize and manage potential toxic side effects. A comprehensive review of somatostatin analog peptide receptor radionuclide therapy is published in Cancer Biotherapy and Radiopharmaceuticals. (2016-10-14)

Mayo Clinic and Massachusetts Institute of Technology receive grant
Mayo Clinic and the Massachusetts Institute of Technology have been awarded a five-year, $9.7 million grant from the National Cancer Institute to support a Physical Sciences-Oncology Center (PS-OC). (2016-10-12)

MGH team identifies possible mechanism for resistance to antiangiogenesis therapy
Massachusetts General Hospital investigators have identified a potential mechanism behind the resistance that inevitably develops to cancer treatment with a combination of chemotherapy and antiangiogenic drugs. (2016-10-12)

PharmaMar announces positive results from its Phase 2 study with PM1183 in BRCA 1/2 MBC
The data was presented at an oral session at the European Society of Medical Oncology. The study meets its primary objective obtaining an overall response rate (ORR) in 41 percent of the patients. In the BRCA 2 subgroup, the ORR was 61 percent, while in those patients with BRCA 1, this was 26 percent. (2016-10-11)

Machine learning technique helps identify cancer cell types
Brown University researchers have developed a new image analysis technique to distinguish two key cancer cell types associated with tumor progression. The approach could help in pre-clinical screening of cancer drugs and shed light on a cellular metamorphosis that is associated with more malignant and drug-resistant cancers. (2016-10-11)

Researchers find genes behind aggressive ovarian and endometrial cancers
In a major breakthrough for ovarian and uterine cancers, Yale researchers have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas (CSs), pointing the way to possible new treatments. The findings are published in the Oct. 10 online early edition of Proceedings of the National Academy of Sciences. (2016-10-10)

Treatment shrinks bladder cancer tumors in patients that can't tolerate chemotherapy
A treatment harnesses the immune system to shrink tumors in bladder cancer patients that cannot take the most effective chemotherapy. (2016-10-10)

NCI-grant explores potential of likely tumor-suppressor gene in kidney cancer
A poorly understood gene that appears super-suppressed in African-Americans with kidney cancer may be a biomarker of a patient's prognosis and a new target for improving it, researchers say. (2016-10-06)

A niche for metastases
Pancreatic cancer is an exceptionally aggressive type of cancer. Frequently, metastases already start to grow in other organs, particularly often in the liver, before the original tumor was even detected. Scientists from the Technical University of Munich have now discovered a molecular mechanism, which is responsible for the prominent susceptibility of the liver to metastases at such an early stage. (2016-10-06)

Why tumors evade immunotherapy
Immunotherapy is a new and highly promising form of treatment for cancer, but in many patients, tumors recur. The members of a research team from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, the Berlin Institute of Health, and Charité -- Universitätsmedizin Berlin now explain why some tumors recur and how this can be prevented. The findings will aid the selection of suitable targets for immunotherapy. (2016-10-06)

Antibody drug conjugates may help personalize radiotherapy for patients with cancer
Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects. (2016-10-04)

Study identifies a potential biomarker for pancreatic tumor grade
This month in the JCI, a team led by Richard Tomasini at INSERM analyzed the expression of proteins in PDA tumors to determine how cells in the tissue surrounding tumors contribute to tumor aggressiveness. They found that cells in tumor-surrounding tissue supported increased tumor growth and metastasis in PDA tumors when they contained extracellular vesicles that expressed a protein called annexin 6. (2016-10-04)

Using nanotechnology to target inoperable tumors from the inside out
A University of Texas at Arlington professor in the Materials Science and Engineering Department is working on research through a National Institutes of Health grant that would create better nanotechnology to treat inoperable cancer tumors. (2016-10-04)

TSRI scientists receive two new grants to explore 'click chemistry' applications
Scientists at The Scripps Research Institute have received a grant of nearly $1.9 million from the National Institutes of Health's National Institute of General Medical Sciences and a grant of $640,000 from the National Science Foundation for two new projects that take advantage of (2016-10-04)

Stretches of repeating DNA tied to cancer progression and survival
Short, unstable DNA stretches, composed of repeated code, may play a greater role in the development and progression of cancer than once thought. These sites are mutation-prone, a tendency that increases in cancer. Using the Cancer Genome Atlas, researchers employed a new technique to analyze sequences of all genes in nearly 6,000 tumors from 18 different kinds of cancer. Their findings give new insights into the basic biology of cancer and point to new ways to type and treat a variety of cancers. (2016-10-03)

HDAC inhibitors show promise against cancer stem cells
A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate stubborn reservoirs of breast and ovarian cancer stem cells (CSCs). (2016-10-03)

Study on minimally invasive laser & 'mini' craniotomy for 'inoperable' brain tumors
A new paper in October issue of the journal Neurosurgical Focus finds the use of laser beneficial for the removal of large, 'inoperable' glioblastoma (GBM) and other types of brain tumors. The paper describes how the authors treat large, inoperable tumors safely with LITT combined with a very small craniotomy. (2016-10-03)

After long-term follow-up, study looks at prognostic factors for breast cancer
A new study published online by JAMA Oncology is long-term analysis of prognostic factors among some patients with breast cancer who were treated with breast-conserving therapy in the EORTC 'boost no boost' trial, which evaluated the influence of a 'boost' dose in radiotherapy. (2016-09-08)

A microRNA signature for infantile hemangioma
In this issue of JCI Insight, Jonathan Perkins of University of Washington and colleagues analyzed infantile hemangioma tumor tissue, infantile hemangioma patient plasma, and non-infantile hemangioma vascular anomalies to identify a set of microRNAs that are specific for infantile hemangioma. (2016-09-08)

Computerized tissue image analysis reveals underlying genomics of ER+ breast cancer
The number of tubules in tumors may predict which women with estrogen receptor positive (ER+) breast cancer will benefit from hormone therapy alone and which require chemotherapy. A computer program to automatically count the tubules correlated with the scores produced by the current best test differentiating between indolent and aggressive ER+ cancers. (2016-09-07)

Experimental drug could stop melanoma, other cancers, research suggests
An experimental cancer drug works differently than intended and shows significant promise for stopping melanoma and possibly other forms of cancer. (2016-09-07)

Fruit flies yield clues on cancerous tumor hotspots
A Florida State University research team, in coordination with a team from Japan, has found that the epithelial tissues that line the surfaces of organs throughout the body intrinsically have hot spots for cancerous tumors. They discovered this by examining a common household pest -- the fruit fly. (2016-09-07)

A new way of taming ions can improve future health care
A group of researchers at Chalmers University of Technology has discovered a completely new way of using lasers to accelerate ion beams. In time, the new technique could possibly give more people access to advanced cancer treatment. The results were recently published in the high impact journal Physical Review Letters. (2016-09-07)

Scientists identify genes that disrupt response to breast cancer treatment
In breakthrough research on breast cancer, a team at the University of Illinois discovered that higher levels of the nuclear transport gene XPO1 indicate when a patient is likely to be resistant to the popular drug tamoxifen. The team is led by food science and human nutrition professor Zeynep Madak-Erdogan. (2016-09-07)

New tumor analysis method identifies high-risk prostate cancer
Scientists at Cedars-Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk. The new findings could help physicians prescribe the most effective treatments for each patient based on how genes are activated in the individual tumor. (2016-09-07)

Technique identifies chemotherapy-resistant cells within acute myeloid leukemia tumors
This month in the JCI, Anthony Letai and colleagues at the Dana-Farber Cancer Institute developed an assay to determine how variability within a population of tumor cells can predict responses to chemotherapy in acute myeloid leukemia patients. (2016-09-06)

Study identifies potential targets for treating triple negative breast cancer
In this issue of the JCI, a team led by Eldad Zacksenhaus at Toronto General Research Institute discovered that the growth of TNBC-like breast tumors is supported by enhanced mitochondrial function. (2016-08-29)

The first epigenetic test to diagnose tumors of unknown origin
An article published in The Lancet Oncology by Dr. Manel Esteller (IDIBELL) shows that it is possible to use a newly-developed epigenetic test called EPICUP® to find out what type of primary tumor is responsible for the metastasis in the patient in cancer of unknown primary cases, which will allow doctors to develop more specific treatments against it. (2016-08-26)

Immune system infighting explains pancreatic cancer's aggression
Conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer. (2016-08-25)

Important advance made with new approach to 'control' cancer, not eliminate it
Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment -- to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination. (2016-08-25)

Collaborative launch of immunotherapy clinical trial for children with brain tumors
A Kids' Brain Tumor Cure Foundation, Solving Kids' Cancer and the Ty Louis Campbell (TLC) Foundation announce their joint financial support of a Phase 1 clinical trial to test the safety and efficacy of combination checkpoint inhibitors in the treatment of children with brain tumors. The collaboration of these three like-minded nonprofits will result in a total contribution of $185,000 to bring this clinical trial to fruition for children battling brain tumors, today. (2016-08-25)

Johns Hopkins scientists track metabolic pathways to find drug combination for pancreatic cancer
Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown cells and mice, Johns Hopkins scientists report that a method they used to track metabolic pathways heavily favored by cancer cells provides scientific evidence for combining anti-cancer drugs, including one in a nanoparticle format developed at Johns Hopkins, that specifically target those pathways. (2016-08-24)

Breast cancer cells found to switch molecular characteristics
A study led by Massachusetts General Hospital investigators reveals how spontaneous changes in the molecular characteristics of tumors can lead to tumors with a mixed population of cells requiring treatment with several types of therapeutic drugs. (2016-08-24)

Not all tumor cells are equal
Scientists led by Dr. Manel Esteller find that colorectal tumors present epigenetic heterogeneity relates to the clinical course of the disease. This heterogeneity can be used as a predictive biomarker. (2016-08-18)

Life expectancy in some CKD patients could be improved with nephron-sparing treatment
A nephron-sparing treatment selection for small renal masses based on the nephrometry score may improve life expectancy in patients with mild or moderate CKD, a study in the Aug. 2016 issue of AJR said. (2016-08-17)

Normalizing tumor oxygen supply could be key factor in the fight against cancer
The lack of oxygen in tumor cells changes the cells' gene expression, thereby contributing to the growth of cancer. This is the main conclusion of a research project led by professor Diether Lambrechts and Dr. Bernard Thienpont, which was published in the renowned scientific journal Nature. The findings are far-reaching, as the study also proved that maintaining a proper oxygen supply in tumors inhibits these so-called 'epigenetic aberrations.' (2016-08-17)

Researchers restore drug sensitivity in breast cancer tumors
A team of Case Western Reserve University School of Medicine cancer researchers has uncovered one way certain tumors resist vital medication. (2016-08-11)

Study finds Hispanic men in California need more screening for colorectal cancer
Colorectal cancer incidence and mortality rates in California have decreased markedly for men and women in all major racial-ethnic groups since 1990, except for Hispanic men -- a disparity that can be improved by greater screening, a study from the UC Davis Institute for Population Health Improvement (IPHI) has found. (2016-08-11)

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