Current Urine News and Events

Current Urine News and Events, Urine News Articles.
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Gulf war illness not caused by depleted uranium from munitions, study shows
Inhalation of depleted uranium from exploding munitions did not lead to Gulf War illness (GWI) in veterans deployed in the 1991 Persian Gulf War, a new study co-authored by a leading researcher of the disease at UT Southwestern suggests. The findings, published today in Scientific Reports, help eliminate a long-suspected cause of GWI that has attracted international concern for three decades. (2021-02-18)

TGen-led study confirms cell-free DNA in urine as potential method for cancer detection
What if a simple urine sample could detect cancer in its very earliest stages when the disease responds more favorably to treatment and improved outcomes are more likely? That was the question posed by scientists at the Translational Genomics Research Institute (TGen), who have found a way of zeroing in on early-stage cancer by analyzing short strands of cell-free DNA in urine. Their study's findings were published today in the scientific journal Science Translational Medicine. (2021-02-18)

Toward a disease-sniffing device that rivals a dog's nose
A new system can detect the chemical and microbial content of an air sample with even greater sensitivity than a dog's nose. Researchers at MIT and elsewhere coupled this to a machine-learning process that can identify the distinctive characteristics of the disease-bearing samples. (2021-02-17)

Liquid biopsy for colorectal cancer could guide therapy for tumors
A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor. Such a biopsy can detect lingering disease and could serve as a guide for deciding whether a patient should undergo further treatments due to some tumor cells evading an initial attempt to eradicate the cancer. (2021-02-12)

Study: New prostate cancer test could avoid unnecessary biopsies
A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. (2021-02-11)

Rapid, reliable on-site drug detection using wearable sensor
Researchers in South Korea have successfully developed a wearable sensor that can detect illegal drugs in sweat by using nanomaterials technology that amplify the optical signal of narcotics to a flexible, body-worn material. The technology enables fast and highly sensitive drug detection: the sweat patch is attached to the skin for a certain period of time and then irradiated with light for testing. It only takes one minute without requiring additional process. (2021-02-08)

HKBU and CUHK launch Spermine Risk Score for prostate cancer diagnosis
Researchers from Hong Kong Baptist University (HKBU) and the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have jointly developed the Spermine Risk Score which, coupled with the use of a urine test, provides a non-invasive and more reliable method for the diagnosis of prostate cancer. In a study conducted by the researchers, about 37% of the patients, who were ultimately found to have no prostate cancer, can avoid undergoing a prostate biopsy procedure. (2021-02-08)

Type 2 diabetes: drugs initially increase glucose production
Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown. A study shows that there is a direct correlation between the elimination of glucose via the kidneys and new glucose production in the liver. (2021-02-08)

Study examines role of biomarkers to evaluate kidney injury in cancer patients
A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells. (2021-02-03)

Cancer can be precisely diagnosed using a urine test with artificial intelligence
The Korea Institute of Science and Technology(KIST) announced that the collaborative research team led by Dr. Kwan Hyi Lee from the Biomaterials Research Center and Professor In Gab Jeong from Asan Medical Center developed a technique for diagnosing prostate cancer from urine within only twenty minutes with almost 100% accuracy. The research team developed this technique by introducing a smart AI analysis method to an electrical-signal-based ultrasensitive biosensor. (2021-01-21)

Lipid biomarkers in urine can determine the type of asthma
In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient's type of asthma. The study, which has been published in the American Journal of Respiratory and Critical Care Medicine, lays the foundation for a more personalized diagnosis and may result in improved treatment of severe asthma in the future. (2021-01-13)

Mechanisms in the kidney that control magnesium and calcium levels discovered
The gene KCTD1 directs production of a protein that functions in the kidney to maintain a normal balance of magnesium and calcium in blood. Loss of KCTD1 impairs the ability of the kidney to properly absorb magnesium and calcium from urine in the kidney, leading to abnormally low magnesium and calcium blood levels, thereby triggering the parathyroid glands to secrete excess parathyroid hormone that in turn leads to metabolic bone disease. (2021-01-12)

Fetal-maternal discordance in APOL1 genotype contributes to preeclampsia risk
Fetal APOL1 kidney risk alleles are associated with increased risk for preeclampsia in African Americans and maternal fetal genotype discordance is also associated with this risk. (2021-01-12)

Study finds new evidence of health threat from chemicals in marijuana and tobacco smoke
Scientists at Dana-Farber Cancer Institute and the Centers for Disease Control and Prevention have uncovered new evidence of the potential health risks of chemicals in tobacco and marijuana smoke. (2021-01-11)

NIH study suggests using cannabis while trying to conceive may reduce pregnancy chances
Women who use marijuana could have a more difficult time conceiving a child than women who do not use marijuana, suggests a study by researchers at the National Institutes of Health. Marijuana use among the women's partners--which could have influenced conception rates--was not studied. (2021-01-11)

Cannabis could reduce fentanyl use, reduce overdose risk: Study
New research suggests that cannabis use by people in care for opioid addiction might improve their treatment outcomes and reduce their risk of being exposed to fentanyl in the contaminated unregulated drug supply. (2020-12-18)

Treatment of opioid use disorder among commercially insured patients in context of COVID-19 pandemic
Opioid use disorder treatment during the early months of the COVID-19 pandemic, including medication fills, outpatient visits and urine tests among privately insured individuals, was compared with 2019 in this study. (2020-12-15)

Analysis finds gaps in care in treating opioid use disorders during pandemic shutdowns
Study finds no decrease in prescription fills or clinician visits in the first three months of the COVID-19 pandemic for patients recently receiving opioid use disorder therapy. On the flip side, the study found that during this period fewer people started new treatment for opioid use disorder and fewer urine tests were given across both new and established patients. Findings identify strengths and weaknesses in telemedicine's role for opioid use disorder during shutdowns and can inform strategies for improvement. (2020-12-15)

'Peecycling' payoff: Urine diversion shows multiple environmental benefits when used at city scale
Diverting urine away from municipal wastewater treatment plants and recycling the nutrient-rich liquid to make crop fertilizer would result in multiple environmental benefits when used at city scale, according to a new University of Michigan-led study. (2020-12-15)

One's trash, another's treasure: fertilizer made from urine could enable space agriculture
From the perspective of future societies, in extremely closed environments such as a space station, self-sufficiency in food cultivation and waste management is critical. However, the technology to achieve this is still lacking. In a new study, scientists from Japan shed light on their most recent breakthrough: a cheap and efficient method to make liquid fertilizer (ammonia) from simplified artificial urine, serving an ideal dual purpose of growing food and treating waste. (2020-12-14)

UL, Ireland, research finds promising treatment to protect kidney function in diabetes
A clinical trial involving researchers at University of Limerick, Ireland has demonstrated the potential benefits of new drugs in protecting kidney function in diabetes. (2020-12-09)

A new era is dawning in diagnosing sexually transmitted infections in men
Researchers and doctors from the University of Tartu and Tartu University Hospital evaluated the use of a novel revolutionary method, flow cytometry, for diagnosing urethritis in Estonian men. The study published in PLOS ONE confirmed the efficiency of the method and showed that most often urethritis was due to chlamydia. Gonorrhoea caused the strongest urethral inflammation. (2020-12-03)

Liver condition identified in patients using urine samples: new research
Fifty fragments of proteins, termed peptides, have been identified in the urine of liver fibrosis patients in a new study that could pave the way for a potential diagnostic urine test for the condition if further validated. (2020-11-16)

'Smart Wrap' implant may help people better control their bladders
An implantable smart wrap that fits safely and securely around the bladder may one day help people who have under-active bladders, a condition that hinders patients from urinating regularly and comfortably, according to an international team of researchers. (2020-11-11)

Veganism: Vitamin B12 is well supplemented, iodine is a matter of concern
Those following a vegan diet have an increased risk of iodine deficiency. This is indicated by the results of a research project from the German Federal Institute for Risk Assessment (BfR). In the 'Risks and benefits of a vegan diet' (RBVD) study project, a BfR research team investigated the nutrient supply in 36 people following a vegan diet and 36 people with a mixed diet. (2020-11-10)

Intensive urate lowering reduces urine albumin excretion
Phase 2 trial of verinurad with febuxostat vs. placebo shows 49% reduction in albuminuria (2020-10-29)

Cell-Free DNA provides a dynamic window into health
A new study presented at the ASHG 2020 Virtual Meeting shows how cfDNA testing can be used to provide insight into a patient's health. (2020-10-26)

Researchers improve the standard method for assessing cardiovascular disease risk
Taking into account two common kidney disease tests may greatly enhance doctors' abilities to estimate patients' cardiovascular disease risks, enabling millions of patients to have better preventive cardiovascular care. (2020-10-14)

Urine-based liquid biopsy test outperforms urine cytology in detecting bladder cancer
Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology (2020-10-09)

Study could be first step in providing personalized care to patients with ureteral stents
Published today in Cell Reports Medicine, researchers at Lawson Health Research Institute and Western University conducted a novel microbiome study to examine bacteria associated with ureteral stents. They found that nearly all the stents, whether visibly coated or not, had unique bacterial profiles that were most associated with a patient's medical condition rather than antibiotic use. For patients with ureteral stents, they may benefit from a personalized approach to care and antibiotic treatment. (2020-09-25)

A better alternative to Phthalates?
In collaboration with the Medical University of South Carolina, researchers at the National Institute of Standards and Technology (NIST) analyzed urine samples from pregnant women to look for the presence of DINCH, which is short for di(isononyl)cyclohexane-1,2-dicarboxylate. They found concentrations of DINCH in most of the urine samples but no evidence of effects in lab assays on two hormones, progesterone and estrogen. (2020-09-25)

Rubbery properties help RNA nanoparticles target tumors efficiently and quickly leave body
A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute shows that RNA nanoparticles have elastic and rubbery properties that help explain why these particles target tumors so efficiently and why they possess lower toxicity in animal studies. (2020-09-14)

Toxic metals can affect student health performance, say scientists from RUDN university
A group of medical and environmental researchers from RUDN University evaluated the level of heavy metals in the organism of first-year university students from different countries of the world. The results of the screening helped the scientists to reveal a relationship between a region of residence and the level of toxic metal in organism. According to their opinion, increased heavy metal levels in the organism of students from Africa and Latin America can have a negative impact on their health and performance. (2020-09-14)

Kidney problems as a young adult may affect thinking skills in midlife
If you have moderate-to-high risk of kidney failure as a young adult, you may be at risk for worse cognitive function in middle age, according to a study published in the Sept. 2, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. (2020-09-02)

Detecting small amounts of virus in early infections
Diagnostic devices that are used at home or in doctors' offices are often not sensitive enough to detect small amounts of a virus that might be present in samples from asymptomatic patients, which can occur in early stage COVID-19. In Biomicrofluidics, scientists report a membrane-based invention that can concentrate the virus content of a sample of urine or saliva, allowing it to be detected. (2020-09-01)

Cardiac biomarker shows stronger associations with kidney disease progression than BP
Identifying biomarkers for kidney disease progression may elucidate disease pathways and inform treatment. In a study of 3,379 adults with kidney disease followed for 12 years (47% with diabetes), elevated levels of N-terminal pro-B-type natriuretic peptide, a cardiac biomarker, were strongly associated with kidney disease progression; associations were stronger than those with systolic blood pressure ?140 mmHg, regardless of heart failure status. These findings highlight the potential role of cardiac disease in kidney disease progression. (2020-08-28)

Reproducing the pathophysiology of polycystic kidney disease from human iPS cells
A joint research project has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. Although cysts derived from renal tubules have been previously documented, this is the first derivation of cysts from collecting ducts, which is more closely related to the pathogenesis of the disease. This research is expected to lead to a better understanding of disease states and the development of new treatment methods. (2020-08-21)

Urine sediment test results, diagnoses vary significantly across nephrologists
A new study shows that nephrologists do not always agree on their interpretation of images from urine sediment tests, which are frequently ordered to evaluate a variety of kidney diseases. Led by researchers at Boston Medical Center and published in JAMA Network Open, the findings indicate the need to standardize education and training around evaluating urine sediment tests to improve the test's reliability, and help prevent misinterpretation and potential patient harm. (2020-08-21)

Ratio of two proteins may add kidneys to the transplant donor pool
An investigation by researchers at Johns Hopkins Medicine, in collaboration with researchers at 13 other medical institutions in the United States, has shown that two proteins found in deceased donor urine can be measured to define which donor organs -- including those with AKI -- are the best candidates for saving the lives of patients with kidney failure. (2020-08-18)

Molecules in urine allow doctors to monitor skin cancer
What if you could simply provide a urine sample rather than undergo a painful surgical procedure to find out if your cancer was responding to treatment? It may seem too good to be true, but researchers at Pavol Jozef Šafárik University in Košice, Slovakia, have identified fluorescent molecules in urine that may allow patients with malignant melanoma to do just that. (2020-08-11)

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