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Current Urine News and Events, Urine News Articles.
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Reducing urinary protein for patients with rare kidney disease slows kidney decline
New findings show that reducing the amount of protein in the urine of patients with focal segmental glomerulosclerosis can significantly slow declines in kidney function and extend time before patients' kidneys fail. (2020-08-10)

Neuroendocrine markers of grief
Researchers have examined what's currently known about the neuroendocrine effects of grief and whether biological factors can predict complicated or prolonged grief after the death of a loved one. The findings appear in the Journal of Neuroendocrinology. (2020-08-05)

Estimating bisphenol exposures in the Australian population
Once found in bottles, food containers, cash register receipts and electronics, bisphenol A (BPA) has been phased out of many products because of health concerns and government regulations. As a result, the production and use of BPA analogs, which are unregulated and poorly understood, have increased. Now, by analyzing urine samples and wastewater, researchers report in ACS' Environmental Science & Technology how human exposure to bisphenols has changed over time in an Australian population. (2020-07-29)

Higher BPA levels linked to more asthma symptoms in children
Children in low-income neighborhoods in Baltimore tended to have more asthma symptoms when levels of the synthetic chemical BPA (Bisphenol A) in their urine were elevated, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health and School of Medicine. (2020-07-28)

Simple urine test could significantly improve detection of adrenal cancer
Using a simple urine test alongside routine imaging for patients with adrenal masses could speed up adrenal cancer diagnosis, improving patient's prognosis and reducing the need for invasive diagnostic procedures, a new multi-centre study published in The Lancet Diabetes & Endocrinology has found. (2020-07-23)

Non-invasive biomarkers to diagnose infant urinary tract obstruction
One in every 500 babies is born with ureteropelvic junction obstruction (UPJO), an obstruction of the ureter that prevents urine from flowing from one or both of the kidneys into the bladder. A group of researchers led by Linda Shapiro and Charan Kumar Devarakonda from UConn's School of Medicine developed an inexpensive, non-invasive panel of five biomarker proteins for the diagnosis and monitoring of UPJO in infants and toddlers. (2020-07-22)

Exhaled biomarkers can reveal lung disease
Using specialized nanoparticles, MIT engineers have developed a way to diagnose pneumonia or other lung diseases by analyzing the breath exhaled by the patient. (2020-07-20)

Women taking menopausal hormone therapy may be more resistant to urine infections
In the first analysis of its kind, US-based doctors have shown that women who take menopausal hormone therapy (MHT, also known as HRT) have a greater variety of beneficial bacteria in their urine, possibly creating conditions that discourage urinary infections. The study also shows that women who suffer from recurrent urine infections have fewer different types of bacteria in urine than women who don't have infections, making them more prone to infections. Presented at the European Association of Urology Virtual Congress (2020-07-17)

Research helping to improve detection of disease in newborn babies
New research will help health-care practitioners to more accurately diagnose disease and illness in newborn babies from urine samples, according to a study by researchers at the University of Alberta and the Universidad Autónoma de Zacatecas. (2020-07-16)

Decision support system within the EHR system can increase provider awareness of CKD
Chronic kidney disease (CKD) affects approximately 37 million U.S. adults and less than 25% are aware of their disease. CKD is readily identified with simple blood and urine tests that are often in a patient's health record yet providers usually do not diagnose the CKD and inform the patient. This study demonstrates that implementation of a decision support system within the electronic health records system can increase provider awareness of CKD. (2020-07-16)

New hope for kidney revival for transplant
Cell therapy delivered directly to the kidney can revive a 'marginal' organ, improving function and could offer new hope for providing more kidneys for transplant. (2020-07-14)

Diabetic nephropathy: Study results on proteomic analysis do not show benefit
First study on a treatment strategy using a proteomic analysis does not clarify which therapeutic consequence of the test could offer a benefit for people with diabetes and high blood pressure. (2020-07-06)

Discovery of new disease-susceptibility gene for steroid-sensitive nephrotic syndrome
An international research collaboration, including Professor IIJIMA Kazumoto et al. (of the Department of Pediatrics, Kobe University Graduate School of Medicine) has revealed that NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome in children. The NPHS1 gene encodes nephrin, a component protein for the renal glomerulus slit diaphragm, which prevents protein from being passed in the urine. It is expected that these successful results will contribute towards understanding of the underlying mechanism and the development of new treatments for childhood nephrotic syndrome. (2020-07-05)

Cryo-electron tomography reveals uromodulin's role in urinary tract infection protection
Free-flowing filaments of Uromodulin protect against urinary tract infections (UTIs) by duping potentially harmful bacteria to attach to their fishbone-like molecular architecture - rather than to sensitive urinary tract tissues - before being flushed out of the body during urination, researchers report. (2020-07-02)

Biomarker test highly accurate in detecting early kidney cancer
A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists, say scientists from Dana-Farber Cancer Institute. (2020-06-22)

Tsetse flytraps: Biotechnology for Africa's rural population
Because the tsetse fly can transmit sleeping sickness, it is commonly combatted with insecticides or caught in traps. Bioscientists at Goethe University have now developed a method for producing the attractants for the traps in a biotechnological procedure. The Frankfurt scientists hope that in the future, the attractants can then be produced locally in rural areas of Africa at low cost. (2020-06-22)

Urine test reveals quality of your diet -- and whether it's the best fit for your body
Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'. (2020-06-22)

Researchers identify key steps in development of kidneys
The discovery of how certain key structures in the kidneys are formed could have important implications for treating renal fibrosis (or scarring), a feature of chronic kidney disease (CKD). (2020-06-18)

Specific kidney proximal tubular injury caused by SARS-CoV-2
A French study [1] investigated acute Fanconi syndrome as a kidney injury associated with COVID-19. The hallmark of the syndrome is increased excretion or loss of certain substances (such as protein, phosphate or glucose) in urine. This renal dysfunction often precede acute kidney injury and disappears again when the kidneys recover. (2020-06-08)

Hope for patients with primary hyperoxaluria type 1
Lumasiran is a subcutaneously administered RNAi therapeutic targeting hydroxyacid oxidase 1 (HAO1) - the gene encoding glycolate oxidase (GO) - in development for the treatment of primary hyperoxaluria type 1 (PH1). The drug has not yet received approval from the European Medicines Agency (EMA) or other health authorities. The data presented today at the ERA-EDTA Congress have been submitted to regulators in support of applications for such approvals. (2020-06-07)

Biochemical alterations revealed in patients with Lesch-Nyhan disease
An international study by the Institute of Neuroscience of the UAB (INC-UAB), Emory University and Hospital Universitario La Paz, published in the PNAS journal, shows that patients suffering from Lesch-Nyhan, a rare neurological disease, present biochemical alterations in skin cells (fibroblasts), urine and cerebrospinal fluid. Researchers have also discovered why these alterations had not been observed before: the high levels of folic acid (B9 vitamin) usually used in cell cultures reverse them. (2020-06-04)

Human waste could help combat global food insecurity
Researchers from Cornell University's College of Agriculture and Life Sciences and the Canadian Light Source (CLS) at the University of Saskatchewan have proven it is possible to create nitrogen-rich fertilizer by combining the solid and liquid components of human waste. (2020-06-02)

New urine testing method holds promise for kidney stone sufferers
An improved urine-testing system for people suffering from kidney stones inspired by nature and proposed by researchers from Penn State and Stanford University may enable patients to receive results within 30 minutes instead of the current turnaround time of a week or more. (2020-05-22)

Certain environmental chemicals linked with poor kidney health
In an analysis of blood and urine samples from 46,748 US adults, elevated levels of seven environmental chemicals were associated with markers of kidney disease. (2020-05-21)

When a spinning toy meets hydrodynamics: Point-of-care technology is set in motion
An IBS research team has reported a diagnostic fidget spinner (Dx-FS) that allows for highly sensitive and rapid diagnosis and prescription only with hand power. (2020-05-18)

Sustainable recovery of nutrients from urine
Most ammonia capture is done through the Haber-Bosch (HB) process, an energy-intensive technique used to produce fertilizer that accounts for 1-2% of the world's annual energy consumption. Columbia engineers report they have recovered ammonia through a new method with a very low level of energy, approx 1/5 of the energy used by HB. And because the technique recycles ammonia in a closed loop, the ammonia can be recaptured for reuse in fertilizer, household cleaners, etc. (2020-05-06)

Race-specific lupus nephritis biomarkers
A University of Houston biomedical researcher has discovered a difference in urinary biomarker proteins of lupus nephritis in patients according to race. The findings have implications for early diagnosis and new treatments. (2020-05-05)

Innovative approach offers option for treating upper tract urothelial cancer
An innovative form of local chemotherapy using a mitomycin-containing reverse thermal gel offers a kidney-sparing treatment option for low-grade upper tract urothelial cancer. (2020-04-29)

Success in specific detection of molecules using deformation of a single atomic sheet
Toyohashi University of Technology developed a test chip using graphene, a sheet material with a thickness of one carbon atom. The chip has a trampoline structure with a narrow gap of 1 micrometer or less formed under a monoatomic graphene film, and can specifically trap a biomarker, a protein included in bodily fluids, on graphene. It's expected that viruses and diseases will be able to be simply and quickly examined using this test chip. (2020-04-28)

Extra payments motivate sobriety and employment among people recovering from addiction
After a yearlong study of people with opioid dependence, Johns Hopkins Medicine researchers report evidence that adding $8 an hour to their paychecks may help those in recovery stay drug free longer, as well as encourage them to get and hold regular jobs. (2020-04-20)

New 'toolbox' for urological cancer detection
Researchers from Ghent University, Belgium, together with researchers from the University of Turku, Finland, have developed a new method for biomarker discovery of urological cancers. The method enables timely diagnosis and treatment of cancer. Urological cancers include e.g. prostate, bladder and kidney cancers. (2020-04-16)

Wastewater test could provide early warning of COVID-19
Researchers at Cranfield University are working on a new test to detect SARS-CoV-2 in the wastewater of communities infected with the virus. The wastewater-based epidemiology (WBE) approach could provide an e?ective and rapid way to predict the potential spread of novel coronavirus pneumonia (COVID-19) by picking up on biomarkers in faeces and urine from disease carriers that enter the sewer system. (2020-03-30)

Astronaut urine to build moon bases
The modules that the major space agencies plan to erect on the Moon could incorporate an element contributed by the human colonizers themselves: the urea in their pee. European researchers have found that it could be used as a plasticizer in the concrete of the structures. (2020-03-27)

How to identify factors affecting COVID-19 transmission
Stanford professor Alexandria Boehm and visiting scholar Krista Wigginton describe potential transmission pathways of COVID-19 and their implications. (2020-03-26)

Published consensus statement offers UTI treatment recommendations
The Journal of the American Medical Directors Association published in its January issue a consensus statement for treating urinary tract infections at post-acute and long-term care centers. Kalin Clifford, Pharm.D., an assistant professor for the Texas Tech University Health Sciences Center Jerry H. Hodge School of Pharmacy was a member of the Infection Advisory Committee of the American Medical Directors Association -- The Society for Post-Acute and Long-Term Medicine that developed the statement. (2020-03-19)

E-cigarette users had substances linked to bladder cancer in urine, review finds
In a review published in the journal European Urology Oncology, researchers compiled the results of 22 different studies that analyzed the urine of people who used e-cigarettes or other tobacco products, including cigarettes, to check for evidence of cancer-linked compounds or biomarkers of those compounds. They found six biomarkers or compounds with a strong link to bladder cancer. (2020-03-19)

Chip for liquid biopsy will help to detect prostate cancer
Researchers of Sechenov University together with their colleagues from Australia used the microfluidics technology to develop a device able to isolate cancer cells from urine of patients with prostate cancer. The study showed high sensitivity and specificity of the new method in diagnosing prostate cancer. The results obtained were published in Cancers. (2020-03-10)

Urine test could reduce unnecessary prostate cancer biopsies
Unnecessary prostate cancer biopsies could be reduced by 60% thanks to new research from the University of East Anglia. Researchers have developed new methods to identify biomarkers for prostate cancer by combining information from multiple parts of urine samples. It is hoped that the breakthrough could help large numbers of men avoid an unnecessary initial biopsy. (2020-03-09)

Researchers announce progress in developing an accurate, noninvasive urine test for prostate cancer
Researchers at the Johns Hopkins Kimmel Cancer Center have made significant progress toward development of a simple, noninvasive liquid biopsy test that detects prostate cancer from RNA and other specific metabolic chemicals in the urine. (2020-02-28)

Clinical factors during pregnancy related to congenital cytomegalovirus infection
A group led by researchers from Kobe University has illuminated clinical factors that are related to the occurrence of congenital cytomegalovirus (CMV) infection in newborns. They revealed that fever or cold-like symptoms during pregnancy, and threatened miscarriage or threatened premature labor in the second trimester were associated with CMV infection in newborns. (2020-02-28)

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