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Current Adverse drug reactions News and Events, Adverse drug reactions News Articles.
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Childhood adversity linked to higher out-of-pocket health care costs in adulthood
A study has found that out-of-pocket health care spending and medical debt are substantially higher when adults have a history of adverse childhood experiences. (2019-03-21)
Electron accelerators reveal the radical secrets of antioxidants
An Osaka University professor has demonstrated for the first time the value of linear particle accelerators for the generation of free radicals inside biological samples. (2019-03-19)
Statin add-on may offer new/another option for reducing LDL-C in high-risk patients
Patients at high risk for a heart attack or stroke who took an investigational drug in addition to a statin had significantly lower LDL, or 'bad' cholesterol, after 12 weeks compared to similar patients who took a placebo in addition to statin therapy, according to research presented at the American College of Cardiology's 68th Annual Scientific Session. (2019-03-18)
Stopping aspirin three months after stenting does not increase risk of death
Patients who stopped taking aspirin three months after receiving a stent to open the heart's arteries but continued taking a P2Y12 inhibitor -- clopidogrel, prasugrel or ticagrelor -- did not experience higher rates of death from any cause, heart attack or stroke after a year compared with those receiving standard therapy, according to research presented at the American College of Cardiology's 68th Annual Scientific Session. (2019-03-18)
Study: Research ties common heartburn medications to kidney disease and failure
Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study. (2019-03-18)
New research identifies potential PTSD treatment improvement
Researchers may have found a way to improve a common treatment for post-traumatic stress disorder (PTSD) by changing how the brain learns to respond less severely to fearful conditions, according to research published in Journal of Neuroscience. (2019-03-18)
Fast-acting agent shows promise in reversing effects of ticagrelor
PB2452 provides immediate and sustained reversal of ticagrelor's antiplatelet effects (2019-03-17)
Ablation better than drugs for reducing Afib, improving QOL, but not for reducing death
Atrial fibrillation is a common arrhythmia that affects an estimated 30 million people worldwide. (2019-03-15)
Study suggests personality tests may improve care for prostate cancer patients
Scientists have found that men with high neuroticism -- between a quarter and a fifth of men in developed countries -- are significantly more likely to suffer from adverse events such as erectile dysfunction and incontinence, which may put their recovery from prostate cancer surgery at risk. (2019-03-15)
Fingermark imaging for drug detection
In a paper to be published in the forthcoming issue in NANO, researchers from Zhejiang have uncovered a novel method of using nanocarrier-based biological fluorescent probes for detecting amphetamine and ketamine in latent fingermark, in a bid to combat drug abuse. (2019-03-14)
Inactive ingredients in pills and capsules may cause allergic, adverse reactions
The majority of oral medications available to consumers contain ingredients that can affect sensitive individuals. (2019-03-13)
'Inactive' ingredients may not be, study finds
MIT and Brigham and Women's Hospital researchers have found that nearly all pills and capsules contain some inactive ingredients that can cause allergic reactions or food intolerances in certain patients. (2019-03-13)
New cholesterol-lowering drug could help patients unable to take statins
A new class of oral cholesterol-lowering drug could help patients unable to take statins due to side effects. (2019-03-13)
The Lancet: Mosquito-killing drug reduced malaria episodes by a fifth among children, according to randomised trial
Childhood malaria episodes could be reduced by 20 percent -- from 2.49 to 2 cases per child -- during malaria transmission season if the whole population were given a drug called ivermectin every three weeks, according to the first randomised trial of its kind including 2,700 people including 590 children from eight villages in Burkina Faso, published in The Lancet. (2019-03-13)
Anti-malarial shows promise in human clinical study
An experimental drug, called DSM265, cured seven volunteers of a Plasmodium falciparum infection, a malaria parasite that is a major cause of morbidity and mortality worldwide. (2019-03-11)
The chemistry behind kibble (video)
Have you ever thought about how strange it is that dogs eat these dry, weird-smelling bits of food for their entire lives and never get sick of them? (2019-03-08)
Study: Life-saving antibiotic receives new use guidelines from researchers around world
An international panel of the foremost researchers on infectious disease and antimicrobials has formed new guidelines on the use of polymyxins, a class of antibiotics employed as a last resort to treat deadly, drug-resistant bacteria. (2019-03-08)
Gene identified that increases risk of antibiotic reaction
Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin. (2019-03-08)
Germ-fighting catheter coating may help prevent infections
In an innovation that may ultimately help to prevent deadly bloodstream infections, a team of biomedical engineers and infectious disease specialists at Brown University developed a coating to keep intravascular catheters from becoming a haven for harmful bacteria. (2019-03-07)
Over half of ED visits for nonmedical prescription drug use are patients under 35
Using nationally representative public health surveillance data to characterize US ED visits for harm caused by nonmedical prescription drug use, investigators at CDC and FDA report in the American Journal of Preventive Medicine that over half these visits are by young adults under 35, and over 40 percent of patients arrive unconscious or after cardiorespiratory failure. (2019-03-06)
How hair dye works (video)
Whether you need a disguise to run from the law or are just trying to emulate *NSYNC-era frosted tips, you may need some chemical assistance to put the hue in your do. (2019-03-01)
Thermodynamic properties of hevein investigated by Lobachevsky University scientists
Hevein is a small protein consisting of forty-three amino acid residues. (2019-02-28)
Nicotine may harm human embryos at the single-cell level
Nicotine induces widespread adverse effects on human embryonic development at the level of individual cells, researchers report Feb. (2019-02-28)
Lab study: Parkinson's researchers test a new approach against motor disorders
Scientists of the German Center for Neurodegenerative Diseases (DZNE) and the University Medical Center Göttingen (UMG) have been able to alleviate motor disorders in mice that resemble those seen in Parkinson's patients. (2019-02-27)
Study identifies predictors of psychiatric events during drug-assisted smoking cessation
Researchers at UC San Diego School of Medicine have identified a clear group of characteristics that predict heightened risk for experiencing increased anxiety or worsening of mood that interferes with daily activities when using a smoking cessation drug. (2019-02-27)
Adipocyte glucocorticoid receptors play a role in developing steroid diabetes
Researchers at Osaka University focused on glucocorticoid receptors (GRs), the receptors for the body's endogenous steroids, clarifying part of the mechanism behind metabolic disturbances caused by steroids. (2019-02-27)
New genetic test improves safety of inflammatory bowel disease treatments
A genetic discovery will make treatment for Crohn's disease and ulcerative colitis safer, by identifying patients who are at risk of potentially deadly drug side effects. (2019-02-26)
Partners in catalysis: An efficient route to unsaturated ketones
A Japanese research team at Kanazawa University synthesized diverse β,γ-unsaturated ketones through direct reaction of aldehydes and allylic alcohols. (2019-02-25)
Elucidation of molecular-targeted drug resistance mechanism by lung cancer cells
We revealed that ALK-positive lung cancer cells, treated with crizonitib, a molecular target drug, acquired resistance to the drug not only by genetic mutation but also by concomitant epithelial-to-mesenchymal transition (EMT). (2019-02-25)
Origin of resistance to lung-cancer drug discovered
Researchers at Kanazawa University report in Nature Communications what causes some lung-cancer patients to have an intrinsic resistance to the drug osimertinib: AXL, a protein belonging to the class of receptor tyrosine kinases. (2019-02-25)
You probably don't have a penicillin allergy
Two McMaster University physicians have five facts about penicillin allergy published today in the Canadian Medical Association Journal (CMAJ). (2019-02-25)
Eating small amounts of peanut after immunotherapy may extend allergy treatment benefits
Regular dietary peanut consumption after completing oral immunotherapy (OIT) or sublingual immunotherapy (SLIT) for peanut allergy may provide continued protection against accidental exposures to the allergen, according to a new study led by Edwin Kim, MD, who presented the findings at the annual American Academy of Allergy, Asthma and Immunology (AAAAI) conference in San Francisco. (2019-02-24)
Is the drug overdose epidemic unique to the United States?
Is the current American drug overdose epidemic an isolated phenomenon? (2019-02-21)
Complex medication regimens are common & sometimes dangerous in patients with lung disease
Patients with interstitial lung disease -- a group of disorders causing progressive scarring of lung tissue -- are often prescribed various medications that specifically target their disease and others that treat their symptoms. (2019-02-21)
Not enough evidence linking noncaloric sweeteners with adverse effects on gut microbiota
There is not enough evidence related to the effects of noncaloric sweeteners on appetite, short-term intake, and risk of suffering from cancer or diabetes, according to the conclusions of this review. (2019-02-21)
Can mixing household cleaners kill you? (video)
When the bathroom starts looking grimy, and it's time to whip out yellow gloves, the only thing that matters is getting the job done quickly. (2019-02-21)
New drug for Duchenne muscular dystrophy clears phase 1 clinical trial testing in boys
Patients with Duchenne muscular dystrophy (DMD) have few treatment options. (2019-02-21)
Risks of shoulder replacement surgery higher than previously thought
The risks associated with shoulder replacement surgery for arthritic conditions are higher than previously estimated, particularly for people under 60 and over 85 years old, finds a study published by The BMJ today. (2019-02-20)
Small benefit of inducing labor over 'wait and see' approach for late-term pregnancies
Inducing labor at 41 weeks of pregnancy leads to a small reduction in birth complications compared with expectant management (a 'wait and see' approach) until 42 weeks in low risk women, finds a clinical trial published by The BMJ today. (2019-02-20)
Oral antifungal drug used to treat yeast infections linked to higher rates of miscarriage
A commonly used medication, fluconazole, used to treat vaginal yeast infections, is linked to higher rates of miscarriage if used during pregnancy, found new research published in CMAJ (Canadian Medical Association Journal). (2019-02-19)
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