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Current Antibody News and Events

Current Antibody News and Events, Antibody News Articles.
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Improving research with more effective antibodies
A new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly. (2019-10-15)
How to enable light to switch on and off therapeutic antibodies
IBS researchers have developed a new biological tool that activates antibody fragments via a blue light. (2019-10-14)
Antibody-based eye drops show promise for treating dry eye disease
Researchers have identified the presence of a specific type of antibody, called anti-citrullinated protein autoantibodies, or ACPAs, in human tear fluid. (2019-10-11)
Long-term dupilumab benefits adolescents with eczema
Results from a phase IIa open-label trial and a subsequent phase III open-label extension trial reinforce findings from an earlier short-term trial that adolescents with moderate-to-severe atopic dermatitis, or eczema, can experience significant improvements with dupilumab. (2019-10-09)
Engineered T cells may be harnessed to kill solid tumor cells
A new Tel Aviv University study finds that a form of immunotherapy used to treat the blood cancer leukemia may be effective in treating other kinds of cancer as well. (2019-10-02)
Study demonstrates antibody responses within 6 weeks of initial vaccination
Early phase clinical trial demonstrates that DNA (DNA-HIV-PT123) and protein (AIDSVAX® B/E) combination vaccine regimens induced high magnitude and long-lasting binding antibody responses and that more rapid potentially protective immune responses were observed when the vaccine regimens were co-administered. (2019-10-01)
Potent antibody curbs Nipah and Hendra virus attack
A monoclonal antibody has been shown to impede the fusion machinery henipaviruses use to merge with the membrane of cells they are attempting to breach. (2019-09-30)
New CAR T cells could help avoid patient relapse in blood cancers
A research team has created CAR T cells that target an alternative B cell-specific surface marker, allowing them to effectively kill blood cancer cells that lack the prototypical target for CAR T therapy, CD19. (2019-09-25)
Saving lives faster: Monash University develops world-first laser incubator for blood
Researchers from BioPRIA, based at Australia's Monash University, together with industry partner Haemokinesis, have developed the world's first blood incubator using laser technology. (2019-09-20)
Antibody 'road block' enables fine-tuning for cardiac recovery
A new study published by Vanderbilt mechanobiology researchers details a possible solution for fine-tuning inflammation and cellular activity in cardiac recovery -- thanks to an antibody initially developed for rheumatoid arthritis.  (2019-09-19)
A promising HIV vaccine shows signs of cross-protective benefits
One of the most successful candidate HIV vaccines to date -- initially tested in Thailand, where it had modest effects -- showed surprisingly strong efficacy when evaluated in a South African cohort, where a different strain of HIV is known to circulate. (2019-09-18)
How new loops in DNA packaging help us make diverse antibodies
It's long been known that our immune cells mix and match bits of genetic code to make new kinds of antibodies to fight newly encountered threats. (2019-09-13)
Can a DNA construction kit replace expensive antibody medication?
Researchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. (2019-09-11)
Nivolumab combined with ipilimumab safe as first-line therapy for lung cancer patients
Combining the PD-1 immune check point inhibitor nivolumab with the monoclonal antibody ipilimumab showed a consistent safety profile in special populations with advanced non-small cell lung cancer (NSCLC), according to research presented today by at the IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer. (2019-09-08)
Following three failed replications of 2016 study, Science maintains 'EEoC'
After having issued an Editorial Expression of Concern on a 2016 Science study by Siddappa N. (2019-09-05)
Mumps study shows immunity gaps among vaccinated people
Immunity against mumps virus appears insufficient in a fraction of college-aged people who were vaccinated in childhood, research from Emory and CDC indicates. (2019-09-02)
Nanoparticles 'click' immune cells to make a deeper penetration into tumors
IBS scientists reported a novel targeting strategy that allows deep tumor penetration of drug-loaded nanoparticles. (2019-08-28)
KAIST vaccine for tick-borne disease 'SFTS' protects against lethal infection
A KAIST research team reported the development of a DNA vaccine for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) which completely protects against lethal infection in ferrets. (2019-08-28)
New sequencing study provides insight into HIV vaccine protection
Scientists led by the US Military HIV Research Program (MHRP) identified a transcriptional signature in B cells associated with protection from SIV or HIV infection in five independent trials of HIV-1 vaccine candidates. (2019-08-28)
Removing cancer's protective barrier could boost immunotherapy treatments
Scientists may have found a way to pull down the protective wall that surrounds tumors, potentially re-exposing them to the killing power of the immune system and immunotherapy treatments, according to a study part funded by Cancer Research UK and published in EBioMedicine today. (2019-08-25)
UC San Diego researchers convert pro-tumor macrophages into cancer killers
University of California San Diego School of Medicine researchers identified a new therapeutic approach in mouse models that halts drug resistance and cancer progression by using an antibody that induces the immune system via macrophages to seek and kill cancer cells. (2019-08-21)
It's Fab! A hidden touch of antibody
Antibodies are key players in our immune system and have been used as biopharmaceuticals. (2019-08-21)
RTS,S vaccine could favor the acquisition of natural immunity against malaria
The RTS,S malaria vaccine could enhance the production of protective antibodies upon subsequent parasite infection, according to a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by 'la Caixa.' The results, published in BMC Medicine, identify the antigens (or protein fragments) that could be included in future, more effective multivalent vaccines. (2019-08-13)
Anti-viral immune discovery could lead to better vaccines
Walter and Eliza Hall Institute researchers have identified a molecular switch that impacts immune responses to viral infections, and whether or not protective antibodies are produced. (2019-08-13)
Gut-brain connection helps explain how overeating leads to obesity
A multi-institutional team led by researchers at Baylor College of Medicine reveals a previously unknown gut-brain connection that helps explain how those extra servings lead to weight gain. (2019-08-12)
Bringing cancer medication safely to its destination
Treating cancer more selectively and more effectively -- this could be achieved with an innovative technology developed by teams of researchers at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Ludwig-Maximilians-Universität München (LMU). (2019-08-08)
Lassa virus' soft spot revealed
A new study identified and then reverse engineered the molecular properties shared by antibodies that are particularly efficient at inactivating or 'neutralizing' Lassa virus. (2019-08-08)
The drug combination effective against bovine leukemia
Scientists have succeeded in reducing levels of the bovine leukemia virus (BLV) in cows with severe infections by combining an immune checkpoint inhibitor and an enzyme inhibitor. (2019-08-01)
'Promising' antibody therapy extends survival in mice with pancreatic cancer
Scientists have found a way to target and knock out a single protein that they have discovered is widely involved in pancreatic cancer cell growth, survival and invasion. (2019-07-31)
Researchers discover therapy to treat drug-resistant acute lymphoblastic leukemia
Researchers from Case Western Reserve University School of Medicine have developed a new combination treatment regimen that enhances the immune system's ability to kill leukemias that do not respond to standard treatments. (2019-07-29)
City of Hope study finds novel mechanism of action for NK cells in checkpoint inhibitor for cancer
City of Hope scientists have discovered that natural killer (NK) cells provide one reason why anti-PD-L1 antibodies might work when tumor cells do not express PD-L1. (2019-07-26)
Preclinical study of therapeutic strategy for Lafora disease shows promise
A team of scientists have designed and tested in mice a novel and promising therapeutic strategy for treating Lafora Disease (LD), a fatal form of childhood epilepsy. (2019-07-25)
Scientists develop promising drug for treating ovarian, pancreatic cancers
Cancer scientists at Houston Methodist have been looking for more effective late-stage treatments for ovarian and pancreatic cancers and may have found one. (2019-07-22)
Maintaining shelf-stable drugs
A new mathematical model describes how highly concentrated antibody solutions separate into different phases, similar to an oil and water mixture, which can reduce the stability and shelf-life of some drugs. (2019-07-22)
Women's stronger immune response to flu vaccination diminishes with age
Women tend to have a greater immune response to a flu vaccination compared to men, but their advantage largely disappears as they age and their estrogen levels decline, suggests a study from researchers at the Johns Hopkins Bloomberg School of Public Health. (2019-07-16)
Tightening the tumor-targeting abilities of checkpoint blockade immunotherapy
Seeking to improve upon existing checkpoint inhibitor therapies, scientists have developed a common checkpoint inhibitor (anti-PD-L1) in a nanoparticle formulation, which were activated specifically at tumor sites in mouse models of cancer. (2019-07-12)
Elegant antibody nanoparticles override immunological tolerance of tumors
Scientists from the Shanghai Institute of Materia Medica (SIMM) of the Chinese Academy of Sciences have developed a tumor enzymatic microenvironment-activatable antibody nanoparticle for robust cancer immunotherapy. (2019-07-12)
In cases when patients under anesthesia experience anaphylaxis, hyperactive immune...
A study of 86 patients reveals how drugs used for anesthesia can induce life-threatening anaphylaxis (a dangerous type of allergic reaction) through an alternative immune pathway. (2019-07-10)
New antibody treatment provides little relief for high-frequency migraine patients
An early assessment reveals that the newly approved antibody treatment Erenumbab does not seem effective among patients who suffer from high-frequency migraines. (2019-07-10)
Old protein, new tricks: UMD connects a protein to antibody immunity for the first time
How can a protein be a major contributor in the development of birth defects, and also hold the potential to provide symptom relief from autoimmune diseases like lupus? (2019-07-09)
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