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Current Antiviral therapies News and Events

Current Antiviral therapies News and Events, Antiviral therapies News Articles.
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New COVID-19 related genes -- helpful and harmful -- found in massive screen
Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus. (2020-10-26)
Mathematical modeling suggests optimal timing for antiviral therapies against COVID-19
A new mathematical modeling study by Ashish Goyal and colleagues, informed by data collected from 25 patients hospitalized with COVID-19 in 4 different countries, offers some important new insights into the optimal timing of 4 different antiviral therapies to combat the disease. (2020-10-23)
Genome archeologists discover path to activate immune response against cancer
Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection. (2020-10-21)
Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites
Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites. (2020-10-20)
Neuropilin-1 drives SARS-CoV-2 infectivity, finds breakthrough study
In a major breakthrough an international team of scientists, led by the University of Bristol, has potentially identified what makes SARS-CoV-2 highly infectious and able to spread rapidly in human cells. (2020-10-20)
Targeting the shell of the Ebola virus
As the world grapples with COVID-19, the Ebola virus is again raging. (2020-10-20)
Drug repurposing
University of New Mexico researchers identify three existing drugs with the potential to clear SARS-CoV-2 infections. (2020-10-16)
Study shows main cell type in the liver has key role in defending against some viruses
Scientists at Scripps Research have uncovered an important disease-fighting role for cells called hepatocytes, which constitute most of the liver. (2020-10-16)
Novel antiviral strategy for treatment of COVID-19
A research team led by Professor Hongzhe SUN, Norman & Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, Faculty of Science, and Professor Kwok Yung YUEN, Henry Fok Professor in Infectious Diseases, Department of Microbiology, Li Ka Shing Faculty of Medicine of the University of Hong Kong (HKU), has discovered a novel antiviral strategy for treatment of COVID-19. (2020-10-15)
Aetion statement on UCSF-led study to inform drug development for COVID-19, future pandemics
Aetion co-authored a study published today in Science, which examined lethal coronaviruses SARS-CoV-2, SARS-CoV-1, and MERS-CoV to identify molecular characteristics of potential treatments. (2020-10-15)
Scientists discover a new mechanism for cellular defense against viral and bacterial infections
Researchers of IDIBAPS, the University of Barcelona and CNIC have coordinated a study, published in Science, which describes a new mechanism of innate immunity by which cells fight viruses and bacteria. (2020-10-15)
Updated recommendations for preventing, treating HIV infection
New evidence on preventing and treating HIV infection in adults was reviewed to update practice recommendations from the International Antiviral (formerly AIDS) Society-USA. (2020-10-14)
Hydroxychloroquine does not counter SARS-CoV-2 in hamsters, high dose of favipiravir does
Virologists from the KU Leuven Rega Institute in Belgium have shown that a treatment with the anti-malaria drug hydroxychloroquine does not limit SARS-CoV-2 coronavirus replication in hamsters. (2020-10-09)
Medicine for multiple sclerosis patients inhibits coronavirus - at least in a test tube
A drug which has already been approved for the treatment of multiple sclerosis patients effectively inhibits the coronavirus when tested on human lung cells. (2020-10-02)
Nitric oxide a possible treatment for COVID-19
Researchers at Uppsala University have found that an effective way of treating the coronavirus behind the 2003 SARS epidemic also works on the closely related SARS-CoV-2 virus, the culprit in the ongoing COVID-19 pandemic. (2020-10-02)
New research provides clues on optimizing cell defenses when viruses attack
Researchers studying interferons, immune response proteins released naturally by human cells when viruses are detected, have uncovered new details on the mechanisms underlying cell defenses. (2020-09-29)
How zika virus degrades essential protein for neurological development via autophagy
Researchers at the University of Maryland (UMD) shed new light on how Zika virus hijacks our own cellular machinery to break down an essential protein for neurological development, getting it to ''eat itself''. (2020-09-28)
Painting a clearer picture of COVID-19
When Saathvik Kannan's father, a faculty member at the University of Missouri, saw his friend, Kamlendra Singh, a research professor at MU, on television being interviewed for his research identifying possible treatments for COVID-19, he called Singh to congratulate him on his work. (2020-09-28)
Shorter time from symptom onset to hospitalization is associated with worse outcome in patients with COVID-19
New research presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, held online) shows that a shorter time from symptom onset to hospitalisation is associated with more serious disease and death in patients with COVID-19. (2020-09-25)
Some severe COVID-19 cases linked to genetic mutations or antibodies that attack the body
Two new studies offer an explanation for why COVID-19 cases can be so variable. (2020-09-24)
Statins reduce COVID-19 severity, likely by removing cholesterol that virus uses to infect
Analyzing anonymized patient medical records, UC San Diego researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why. (2020-09-23)
UofA lab uncovers new mechanism of action against SARS-CoV-2 by antiviral drug remdesivir
Researchers at the University of Alberta have discovered a novel, second mechanism of action by the antiviral drug remdesivir against SARS-CoV-2, according to findings published in the Journal of Biological Chemistry. (2020-09-23)
Viral load predicts mortality rate in hospitalized patients with cancer and COVID-19
Higher viral loads are associated with a greater risk of death among cancer and non-cancer patients hospitalized with coronavirus disease 2019 (COVID-19), researchers report September 15 in the journal Cancer Cell. (2020-09-16)
Progress toward antiviral treatments for COVID-19
COVID-19 is caused by the virus SARS-CoV-2, which is structurally similar to the viruses that cause SARS-CoV and MERS-CoV. (2020-09-15)
Researchers identify key role of immune cells in brain infection
Researchers at the University of Liverpool have identified the specific type of immune cell that induces brain inflammation in herpes simplex virus (HSV) encephalitis. (2020-09-15)
Decreased MIR2911 absorption in human with SIDT1 polymorphism fails to inhibit SARS-CoV-2
In a new study in Cell Discovery, Liang Li and Chen-Yu Zhang's group at Nanjing University and two other groups report that SIDT1 polymorphism remarkably decreases HD-MIR2911 absorption in human. (2020-09-11)
Human norovirus strains differ in sensitivity to the body's first line of defense
Human norovirus strains differ in sensitivity to interferon, one of the body's first line of defense. (2020-09-10)
Designed antiviral proteins inhibit SARS-CoV-2 in the lab
Computer-designed miniproteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19. (2020-09-09)
Study finds botanical effective for chemo-resistant colon cancer
The natural botanical Andrographis paniculata, when given in conjunction with chemotherapy, may eventually change the way doctors treat chemotherapy-resistant colorectal cancer. (2020-09-09)
Delayed immune responses may drive COVID-19 mortality rates among men and the elderly
COVID-19 (SARS-CoV-2) infections tend to be more severe among older adults and males, yet the mechanisms underlying increased mortality in these two demographics are unknown. (2020-09-08)
Researchers identify nanobody that may prevent COVID-19 infection
Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells. (2020-09-04)
Common cold combats influenza
As the flu season approaches, a strained public health system may have a surprising ally -- the common cold virus. (2020-09-04)
Subtypes and developmental pathways of innate T cells identified
Study finds T cells differentiate into memory cells before meeting antigens - a clue to developing new immunotherapy (2020-09-02)
Kidneys infected with hepatitis C can be safely transplanted into healthy recipients
Kidneys infected with hepatitis C can be safely transplanted into healthy recipients (2020-09-02)
MSK study links inflammation to Alzheimer's disease development
Scientists at the Sloan Kettering Institute have discovered a direct link between the immune response to viruses and bacteria and the development of plaques in the brain that characterize Alzheimer's disease. (2020-09-02)
Severe Covid-19 despite or even due to the strong immunity
A weak immune response isn't the cause of dangerous lung failure in severe Covid-19 infections. (2020-09-01)
Scent-sensing cells have a better way to fight influenza
Smell receptors that line the nose get hit by Influenza B just like other cells, but they are able to clear the infection without dying. (2020-09-01)
Research brief: How genetics could impact COVID-19 treatments
U of M study looked at how pharmacogenomics could improve the safety and effectiveness of COVID-19 drug therapies. (2020-08-27)
Expanding researchers' knowledge of the microbial defense toolkit
A new study identifies a wide array of previously unknown molecular functions and enzymatic activities microbes use to protect against viral threats. (2020-08-27)
MHC class II transactivator CIITA induces cell resistance to Ebola Virus and SARS-like coronaviruses
Discoveries from the Benaroya Research Institute at Virginia Mason (BRI) have identified a new cellular protection pathway that targets a common vulnerability in several different pandemic viruses, and collaborators at Case Western Reserve University, Boston University School of Medicine and MRIGlobal have shown that this pathway can protect cells from infection by Ebola virus and coronaviruses, like SARS-CoV-2. (2020-08-27)
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