Current Arthritis News and Events

Current Arthritis News and Events, Arthritis News Articles.
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TTUHSC scientist takes next step in search for bone disease treatment
For more than a decade, TTUHSC's Hiranmoy Das, Ph.D., has been investigating how KLF2 influences the development of bone and musculoskeletal diseases. Most recently, Das attempted to determine if inducing KLF2 levels in dental pulp derived stem cells will promote osteoblast and the building of new bone. His study, ''KLF2 regulates dental pulp-derived stem cell differentiation through the induction of mitophagy and altering mitochondrial metabolism,'' was published in the September issue of Redox Biology. (2020-11-20)

Link between periodontitis and cardiovascular disease in individuals with rheumatoid arthritis
Rates of both periodontal disease and cardiovascular disease are elevated in individuals with rheumatoid arthritis. New research published in Arthritis & Rheumatology suggests that immune responses to certain bacteria that cause periodontal disease may play a role in patients' higher cardiovascular disease risk. (2020-11-18)

Study explores sleep apnea, autoimmune disease link
New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies. (2020-11-17)

Novel technique 'stuns' arthritis pain in shoulder and hip
A novel outpatient procedure offers lasting pain relief for patients suffering from moderate to severe arthritis in their hip and shoulder joints, according to a study presented at the annual meeting of the Radiological Society of North America (RSNA). Researchers said the procedure could help reduce reliance on addictive opiates. (2020-11-16)

Approved JAK inhibitor baricitinib shows promise against cytokine storm in COVID-19 clinical study
A clinical study involving 601 patients in Italy and Spain suggests that the JAK inhibitor drug baricitinib may enhance survival rates of patients (2020-11-13)

Scientists pinpoint two new potential therapeutic targets for rheumatoid arthritis
A collaborative team of scientists has pinpointed two new potential therapeutic targets for rheumatoid arthritis - a painful inflammatory disease that affects an estimated 350 million people worldwide. (2020-11-12)

Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis
A study from investigators at Hospital for Special Surgery (HSS) and Brigham and Women's Hospital in Boston has found that the synovial fluid and blood of people experiencing checkpoint inhibitor-induced arthritis is populated by a type of T cells rarely seen in people with other types of inflammatory arthritis. The findings are being presented at the virtual American College of Rheumatology annual meeting. (2020-11-08)

Kids with arthritis in less affluent families report longer period of morning stiffness
Children with arthritis affecting five or more joints, called polyarticular juvenile idiopathic arthritis (polyarticular JIA), living in less affluent families were twice as likely to report more than an hour of morning joint stiffness, compared to their counterparts from more affluent families, according to a study by investigators at Hospital for Special Surgery (HSS). Parents and physicians should be aware that morning joint stiffness may indicate early disease symptoms of polyarticular JIA and serve as a more reliable indicator than pain. (2020-11-07)

Black patients with RA less likely to receive biologic, more likely to get glucocorticoids
A new study reveals that Black patients with rheumatoid arthritis (RA) were less likely to be prescribed a biologic treatment and more likely to use glucocorticoids, which carry a risk of serious long-term side effects. This study highlights ongoing racial disparities in the care of patients with rheumatic disease. Details of the study was shared at ACR Convergence, the ACR's annual meeting. (2020-11-06)

Hydroxychloroquine not linked to longer heart rhythm intervals in RA or lupus patientsti
New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, discovers that use of hydroxychloroquine, a generic drug, does not cause any significant differences in QTc length or prolonged QTc, key measures of heart rate, in people with rheumatoid arthritis (RA) or systemic lupus erythematosus. (2020-11-06)

COVID-19 infection rates low in people with rheumatic diseases, most report mild illness
A new study shows that the COVID-19 infection incidence has been low in people with rheumatic diseases, and most of those infected experience a mild course of illness. Additionally, fatalities have been low among rheumatic disease patients infected with COVID-19. Details of this research was presented at ACR Convergence, the American College of Rheumatology's annual meeting. (2020-11-06)

Therapeutic drug monitoring does not improve remission for patients starting infliximab
New research presented at ACR Convergence, the American College Rheumatology's annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care. (2020-11-06)

Minority patients with rheumatic diseases have worse COVID-19 outcomes
New research at ACR Convergence, the American College of Rheumatology's annual meeting, reveals that people of color with rheumatic disease have worse health outcomes from COVID-19 infection, are more likely to be hospitalized to treat their coronavirus infection, and are more likely to require invasive ventilator treatment. (2020-11-06)

Global survey reveals that few children with rheumatic disease report contracting COVID-19
Results from a large, international survey shows that only a small fraction of children with rheumatic diseases reported contracting COVID-19. Those who did become infected with COVID-19 all had benign outcomes and did not develop significant complications, despite the fact that most children were taking immunosuppressive medications. The research was presented at ACR Convergence, the American College of Rheumatology's annual meeting. (2020-11-06)

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments
The American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Convergence, the ACR's annual meeting. (2020-11-06)

New RA guideline emphasizes maximizing methotrexate and biologics, minimizing steroids
The American College of Rheumatology (ACR) will preview its 2020 Guideline for the Management of Rheumatoid Arthritis (RA) at ACR Convergence, the ACR's annual meeting. (2020-11-06)

Reducing dementia in patients with rheumatoid arthritis
The incidence of dementia in patients with rheumatoid arthritis is lower in patients receiving biologic or targeted synthetic disease modifying antirheumatic drugs (DMARDs) than in patients who receive conventional synthetic DMARDs, according to a new study. The study was presented at the virtual annual meeting of the American College of Rheumatology. (2020-11-06)

Analysis reveals high burden of musculoskeletal disorders across the globe
Musculoskeletal disorders--which affect muscles, tendons, ligaments, bones, and joints--can severely affect individuals' physical and mental health, and they're especially prevalent among aging adults. Although many researchers are studying these conditions and their rates in different regions of the world, no study to date has provided an overview of the burden of all musculoskeletal disorders. Investigators have now done so in Arthritis & Rheumatology, an official journal of the American College of Rheumatology. (2020-11-05)

Different outcomes by race/ethnicity among patients with COVID-19 and rheumatic disease
Among US patients with rheumatic disease and COVID-19, racial/ethnic minorities had higher risks of needing to be hospitalized and put on ventilators. The findings come from an analysis published in Arthritis & Rheumatology. (2020-11-04)

Cancer treatment could be replicated for COVID-19
Beta-blockers could potentially be used to treat COVID-19, according to a new international study by Italian and Australian scientists. (2020-11-02)

New research predicts whether rheumatoid arthritis patients will respond to treatment
A new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsiveness to disease modifying anti-rheumatic drugs (DMARDs). (2020-10-27)

Tissue grafts of both bone and cartilage could regenerate damage to a crucial jaw joint
Scientists have engineered tissue grafts that, in pigs, regenerated both bone and cartilage in the temporomandibular joint (TMJ), a part of the jaw that can cause debilitating pain and disability when damaged. (2020-10-14)

Children's pain 'swept under the carpet for too long' - Lancet Commission
The launch of the Lancet Child and Adolescent Health Commission - the first ever to address paediatric pain - aims to raise the profile of children's pain from early years to early adulthood. (2020-10-13)

When it comes to arthritic bone spurs, stem cells hurt instead of heal
The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of Rheumatic Diseases. By resolving the cellular origins of osteophytes, the research provides clues for how to target these painful bone spurs that develop at the edge of joints in many arthritis patients. (2020-10-09)

Physical activity and sleep in adults with arthritis
A new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthritis. (2020-10-07)

Genetic analysis links obesity to higher rheumatoid arthritis risk
An analysis of genetic data collected from more than 850,000 individuals of European ancestry has found a link between obesity-related genes and rheumatoid arthritis. (2020-09-23)

BrainHealth's SMART methodology helps patients make more informed treatment decisions
Researchers at Center for BrainHealth® collaborated with scientists at the University of North Carolina at Chapel Hill to examine whether the SMART program affects people's abilities to make informed decisions about their medical treatment options. Patients with rheumatoid arthritis are often reluctant to take antirheumatic drugs because of perceptions about the drugs' risks and benefits. The findings point to an approach that helps these patients, and other people, make more informed decisions about their health. (2020-09-23)

Is rheumatoid arthritis two different diseases?
While disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with autoantibodies, according to a new study published this week in PLOS Medicine by Xanthe Matthijssen of Leiden University Medical Center, Netherlands, and colleagues. The findings add to a growing body of evidence that RA with and without autoantibodies are two distinct conditions. (2020-09-22)

Key discovery in psoriatic arthritis points way for developing targeted treatments
The strongest evidence yet of a single cause for psoriatic arthritis has been discovered by researchers. The disease may be activated by the same trigger in different patients which, if identified, could move towards creating therapies that would prevent psoriatic arthritis, and potentially providing a cure. (2020-09-21)

Tracking the working dogs of 9/11
A study of search and rescue dogs led by the School of Veterinary Medicine showed little difference in longevity or cause of death between dogs at the disaster site and dogs in a control group. (2020-09-21)

Artificial intelligence detects osteoarthritis years before it develops
Researchers have created a machine-learning algorithm that can pick up on subtle signs of osteoarthritis - too abstract to register in the eye of a trained radiologist - on an MRI scan taken years before symptom onset. (2020-09-21)

Study shows that rheumatoid arthritis is associated with a 23% increased risk of developing diabetes
A new study presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD), held online this year, shows that rheumatoid arthritis (RA) is associated with a 23% increased risk of type 2 diabetes (T2D), and may indicate that both diseases are linked to the body's inflammatory response. (2020-09-20)

Does the Mediterranean diet protect against rheumatoid arthritis?
Previous research has demonstrated a variety of health benefits associated with the Mediterranean diet, which is rich in olive oil, cereals, fruit and vegetables, fish, and a moderate amount of dairy, meat, and wine. Now results from an analysis published in Arthritis & Rheumatology suggest that the diet may also help prevent rheumatoid arthritis in individuals who smoke or used to smoke. (2020-09-10)

Improving the transition from pediatric to adult rheumatology care
As children with chronic rheumatic illnesses age, it's important that they experience a smooth transition from pediatric to adult care. A study published in Arthritis Care & Research has identified certain factors that are important during this time. (2020-09-10)

Study: Why people with knee osteoarthritis experience different kinds of pain
People with more pain sensitization were more likely to suffer from constant and unpredictable pain, rather than just intermittent pain. This study has identified for the first time a potential underlying mechanism in the nervous system responsible for why people experience varying pain patterns with knee osteoarthritis. (2020-09-04)

Heart disease signs improve when using arthritis medication
Drugs used to treat initial signs of rheumatoid arthritis also improve the early stages of heart disease, according to new research (2020-09-02)

New analysis shows hydroxychloroquine does not lower mortality in COVID-19 patients, and is associated with increased mortality when combined with the antibiotic azithromycin
A new meta-analysis of published studies into the drug hydroxychloroquine shows that it does not lower mortality in COVID-19 patients, and using it combined with the antibiotic azithromycin is associated with a 27% increased mortality. The study is published in Clinical Microbiology and Infection. (2020-08-26)

Most adults with lupus or common types of arthritis have similar risks of getting admitted to hospital as other COVID-19 patients
Most adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to dampen their altered immune system, the cause of their disease. (2020-08-25)

Lab-created molecule achieves positive results in the treatment of arthritis
Tested in mice with genetically induced arthritis, the substance decreased the area affected, reduced local swelling, and assuaged the pain associated with the inflammatory process. (2020-08-11)

Change isn't a good thing for Japanese rheumatoid arthritis patients
Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA) that dramatically increases the risk of death. In a recent study led by Osaka University, researchers identified a genetic variant that increases the risk of ILD among Japanese RA patients, most likely by altering the expression of the RPA3 gene and triggering scarring of lung tissue. Identifying risk variants associated with RA-ILD will help unravel the underlying causes of disease in different populations. (2020-08-09)

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