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Current Bisphosphonates News and Events

Current Bisphosphonates News and Events, Bisphosphonates News Articles.
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Hip fracture risk linked to nanoscale bone inflexibility
New research has highlighted a preventative treatment gap in patients prone to bone fractures who are otherwise healthy. (2020-08-26)
New strategy against osteoporosis
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health. (2020-08-05)
Bone drug may be beneficial for knee osteoarthritis
Bisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear to be safe and beneficial for osteoarthritis patients. (2020-08-05)
Fracture risk associated with bisphosphonate drug holidays
Bisphosphonates have been shown to reduce the risk of osteoporotic fractures. (2020-07-29)
Osteoporosis treatment may also protect against pneumonia
A recent study published in the Journal of Bone and Mineral Research found that nitrogen-containing bisphosphonates (N-BPs) such as alendronate, which are widely used to treat postmenopausal osteoporosis, are linked with lower risks of pneumonia and of dying from pneumonia. (2020-06-03)
Osteoporosis drugs linked to reduced risk of premature death
A large cohort study has revealed a common osteoporosis drug significantly decreases premature mortality risk, likely related to a reduction in bone loss. (2019-08-12)
IOF review of impact of drug holidays on bone health
The impact of interruption of anti-osteoporosis treatment in patients on therapy with bisphosphonates or denosumab is reviewed in a new IOF Working Group paper. (2019-07-08)
Study supports bisphosphonate use prior to denosumab to prevent loss of bone mineral density in post-menopausal women
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2019) finds the risk of bone mineral density (BMD) loss after denosumab discontinuation is associated with younger age, high bone turnover markers, and not receiving the bisphosphonate, zoledronate, prior to initiation of denosumab. (2019-06-13)
SWOG spotlights high-impact research at ASCO
At ASCO 2019, SWOG investigators will report on 16 group-led trials, one jointly-led study, and another 12 involving partners. (2019-05-22)
USC research shows remedy for painful jaw disease
USC researchers and collaborators report a breakthrough to prevent osteonecrosis of the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis. (2019-04-11)
Many postmenopausal women do not receive treatment for osteoporosis
The benefits of treating osteoporosis in postmenopausal women outweigh the perceived risks, according to a Clinical Practice Guideline issued today by the Endocrine Society. (2019-03-25)
Bisphosphonates increasingly prescribed to the women most likely to benefit
In recent years, women who start taking bisphosphonates (BPs) to treat osteoporosis and prevent fracture have trended from younger to older and from having osteopenia to having osteoporosis, researchers report. (2019-03-23)
US older women three times as likely to be treated for osteoporosis as men
Older women in the US are three times as likely to be treated for osteoporosis as men of the same age, reveals research published online in the Journal of Investigative Medicine. (2019-02-14)
The delicate balance of treating growing but brittle bones
Turning off a bone receptor protein could potentially treat osteoporosis in children without affecting bone growth. (2019-02-01)
Sex-specific effects of DHEA on bone mineral density and body composition
Women 55 and older have an increased risk of bone and muscle loss but therapy with the hormone Dehydroepiandrosterone (DHEA) may help prevent bone loss and increase muscle mass in older women, according to a new study led by Catherine M. (2018-12-04)
SWOG shares trio of studies at San Antonio breast cancer symposium
SWOG Cancer Research Network members will share the results of three studies at the San Antonio Breast Cancer Symposium, an international gathering of breast cancer physicians and researchers that starts today, with an estimated 7,500 attendees expected from more than 90 countries. (2018-12-04)
Failure to discontinue medications can contribute to inappropriate prescribing
The continuation of drugs that are not intended to be taken indefinitely is a substantial and common problem that could contribute to over-medication, particularly in the elderly. (2018-11-12)
Study: Denosumab effective in treating osteoporosis in transfusion dependent thalassemia
For patients with osteoporosis caused by transfusion-dependent thalassemia (TDT), a twice-yearly injection appears to improve spinal bone mineral density, according to a new study. (2018-10-31)
Study sheds light on atypical periprosthetic femoral fractures
Following surgery, some patients experience a broken bone around the implants of a total hip replacement--called a periprosthetic femoral fracture. (2018-10-03)
Patients 65 years of age or older with hip or spine fracture should be treated for osteoporosis
A coalition of the world's top bone health experts, physicians, specialists, and patient advocacy groups today released their clinical recommendations to tackle the public health crisis in the treatment of osteoporosis and the debilitating and often deadly hip and spine fractures caused by the disease. (2018-09-29)
Investigating what keeps metastatic breast cancer in check
New evidence suggests that inflammation may help prevent growth of tumor cells that have spread, with important implications for clinical trials. (2018-08-27)
Osteoporosis drug may benefit heart health
The osteoporosis drug alendronate was linked with a reduced risk of cardiovascular death, heart attack, and stroke in a Journal of Bone and Mineral Research study of patients with hip fractures. (2018-05-11)
Fifteen percent of osteoporosis patients who take 'drug holidays' suffer bone fractures
A Loyola Medicine study has found that 15.4 percent of patients who take so-called 'drug holidays' from osteoporosis drugs called bisphosphonates experienced bone fractures. (2018-05-04)
Exercise may be best intervention to prevent falls among elderly, according to new study published during Falls Prevention Month
Exercise alone or in combination with other assessments and interventions appears to be the most effective strategy for preventing falls causing injury among older people, a new study has found. (2017-11-07)
Women who discontinue bisphosphonates for two years or more have higher hip fracture risk
Women who took a drug holiday (temporary or permanent discontinuation of a medicine) from using bisphosphonates for more than two years have a significantly higher risk of a hip fracture compared to others who continued their treatment, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego. (2017-11-04)
Confusion about long-term treatment of osteoporosis clarified
Osteoporosis is a common disorder among postmenopausal women which results in an increased risk of fractures. (2017-10-11)
Study highlights underlying mechanisms of fractures associated with osteoporosis drug
There is no disputing that the use of bisphosphonates -- with brand names such as Fosamax, Boniva and Reclast -- is proven to combat bone loss and fragility fractures in millions of osteoporosis patients for whom a fracture could be debilitating, even life-threatening. (2017-07-31)
Quantifying lower limb muscle weakness in Osteogenesis Imperfecta type IV
To date, muscle function, and in particular that of the lower extremity, in OI type IV has not been investigated systematically. (2017-07-26)
Promising new therapeutic approach for debilitating bone disease
Australian researchers have demonstrated that a new type of therapeutic could greatly reduce bone disease in patients with the bone cancer, multiple myeloma. (2017-06-29)
Specific long-term therapy may not prevent fractures in older women
Bisphosphonates are sometimes used to treat osteoporosis. Studies have shown that the risk for bone fractures lessens when women with low bone mineral density take these medications for between one and four years. (2017-06-02)
Mutation discovered that, linked with drug, predisposes osteoporosis patients to femur fracture
Bisphosphonates are the first line of fracture prevention treatment in osteoporosis. (2017-05-04)
Study finds worse survival when specific thyroid cancers spread to bone
In the largest-known study on bone metastases in thyroid cancer, researchers at the University of Michigan Comprehensive Cancer Center found that patients with follicular and medullary thyroid cancer had the highest rate of cancer-related bone lesions and fractures and an increased risk of death. (2017-04-14)
Benefits and harms of osteoporosis medications unclear for patients with CKD
More research is needed to determine the benefits and harms of osteoporosis medications on bone mineral density, fracture risk, and safety among patients with chronic kidney disease (CKD). (2017-04-10)
Making bones stronger
New treatments for osteoporosis are desperately needed. Two University of Delaware scientists report estimates of potentially the most effective dosage of a particular peptide, with results that could raise density levels in badly degraded bones back to healthy levels. (2017-03-29)
Drug used to treat weak bones associated with micro-cracks
A type of drug used to treat weak bones is associated with an increased risk of 'micro-cracks' in bone, according to new research. (2017-03-03)
Study provides insights on optimal treatment of Paget's disease of bone
In a study of patients with Paget's disease of bone--a common skeletal disorder that can lead to bone deformity, fractures, osteoarthritis, and bone pain -- long-term intensive bisphosphonate therapy conferred no clinical benefit over giving bisphosphonates only when patients felt bone pain. (2017-02-08)
Bone markers as screening strategy for patient adherence to osteoporosis medications
This IOF and ECTS Working Group position paper proposes measuring specific bone turnover markers (BTMs) in patients who have initiated use of oral bisphosphonates for postmenopausal osteoporosis as a practical way to identify low adherence. (2017-01-30)
Study examines the effects of osteoporosis drugs in children with genetic bone disorders
Previous case reports in patients with osteogenesis imperfecta (OI) have suggested that treatment with bisphosphonates, which are commonly prescribed for osteoporosis, may be associated with atypical femur fractures. (2017-01-09)
Study finds one-third of women taking bisphosphonates remain at risk for fracture
A recent study of oral bisphosphonates, the most commonly prescribed osteoporosis treatment, found that approximately a third of women prescribed these drugs continue to be at elevated risk for bone fracture, an outcome that may have several origins. (2016-06-06)
Expert panel evaluates role of osteoporosis medications in fracture healing
Using a structured expert-opinion process, an International Osteoporosis Foundation expert panel has written a consensus report on the use of osteoporosis medications in patients with recent fracture and the potential role of these medications in promoting fracture healing. (2016-04-27)
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