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The unexpected repair function of neutrophils
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered that neutrophils, the most abundant cells of the innate immune system, have many more functions in the body than previously thought. (2020-10-23)
Aging alone does not explain kidney pathology
Histopathology in non-neoplastic kidney tissue from 1,347 nephrectomy specimens showed very limited histopathologic changes in subset of older individuals. (2020-10-21)
Ketamine, a painkiller used by the army, does not impair tolerance to blood loss
A low dose of ketamine, administered intravenously, does not alter a healthy human's tolerance to blood loss. (2020-10-21)
MSK-led studies support the concept of 'cancer environment immunotherapy'
Two MSK-led studies published in the journal Nature support the idea of using immunotherapy drugs to treat the environment surrounding a tumor as an indirect way to combat cancer. (2020-10-21)
Existing heart drugs may help cancer patients respond better to PD(L)1 immunotherapy
Researchers have found that a class of commonly-used heart drugs may also improve patients' responses to anti-cancer immunotherapies called PD(L)1 inhibitors, according to preliminary findings to be presented at the 32th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, which is taking place online. (2020-10-21)
Researchers identify genetic variants linked to toxic side effects from bevacizumab
In the largest study of its kind, researchers have found two common genetic variants that can be used to predict whether or not cancer patients might suffer severe adverse side-effects, such as high blood pressure, from the drug bevacizumab. (2020-10-21)
Vitamin D: Consumption of high-dose food supplements is unnecessary
The German Federal Institute for Risk Assessment (BfR) has prepared a health risk assessment for products sold on the market as food supplements containing a daily dose of chole-calciferol -- the precursor to active vitamin D -- of 50 or 100 micrograms. (2020-10-20)
CBD helps reduce lung damage from COVID by increasing levels of protective peptide
One way CBD appears to reduce the 'cytokine storm' that damages the lungs and kills many patients with COVID-19 is by enabling an increase in levels of a natural peptide called apelin, which is known to reduce inflammation and whose levels are dramatically reduced in the face of this storm. (2020-10-19)
New evidence to guide the practice of blood transfusions in children with severe malari
Blood transfusions increase the survival of children admitted to the hospital with complications by severe malaria, and could be beneficial even at higher haemoglobin levels than those currently recommended. (2020-10-19)
Study reveals kidney disease or injury is associated with much higher risk of mortality for COVID-19 patients in ICU
New research published in Anaesthesia (a journal of the Association of Anaesthetists) reveals the much higher risk of mortality faced by COVID-19 patients in intensive care who have chronic kidney disease (CKD) or, those who develop new (acute) kidney injury (AKI) as a result of developing COVID-19. (2020-10-16)
Research could change how blood pressure is managed in spinal cord injury patients
New research from the International Collaboration on Repair Discoveries (ICORD) challenges the current standard for managing blood pressure in people with spinal cord injury (SCI). (2020-10-15)
New insight into neovessel formation shows promise in future treatment of cardiovascular diseases
A new study by researchers at the University of Eastern Finland provides novel insight into the previously unknown effects of factors regulating blood vessel formation. (2020-10-14)
Studies offer new evidence for possible link between blood type & COVID-19 susceptibility
Two studies published today in Blood Advances suggest people with blood type O may have a lower risk of COVID-19 infection and reduced likelihood of severe outcomes, including organ complications, if they do get sick. (2020-10-14)
Ancient tiny teeth reveal first mammals lived more like reptiles
Pioneering analysis of 200 million-year-old teeth belonging to the earliest mammals suggests they functioned like their cold-blooded counterparts - reptiles, leading less active but much longer lives. (2020-10-12)
Revealing the reason behind jet formation at the tip of laser optical fiber
When an optical fiber is immersed in liquid, a high temperature, high speed jet is discharged. (2020-10-12)
Scientists discover mosquitoes' unique blood-taste detectors
Scientists aren't sure how mosquitoes sense taste of blood, or how they know that this, of all things, is something to gorge on. (2020-10-12)
New method for in utero 4D imaging of baby hearts may aid diagnosis of congenital heart disease
Researchers at King's College London have developed a new method for helping detect congenital heart disease of a baby in pregnant mothers using MRI. (2020-10-05)
Discovery holds potential for reversing vision loss
Scientists at the Oklahoma Medical Research Foundation have identified a compound that could reverse the vision loss that occurs when blood vessels in the eyes of premature infants and adults grow out of control. (2020-10-05)
High blood pressure linked to baroreflex in rats
Researchers describe a newly observed phenomenon in the way blood pressure is maintained in certain rats. (2020-10-03)
Users of blood pressure medicine have a lower risk of dying from influenza and pneumonia
Thousands of Danes use ACE inhibitors or angiotensin II receptor blockers against elevated blood pressure or heart problems, and they may have an improved chance of surviving severe influenza or pneumonia infections. (2020-10-02)
Nitric oxide a possible treatment for COVID-19
Researchers at Uppsala University have found that an effective way of treating the coronavirus behind the 2003 SARS epidemic also works on the closely related SARS-CoV-2 virus, the culprit in the ongoing COVID-19 pandemic. (2020-10-02)
Tumor progression depends on the tumor microenvironment
Researchers from Tokyo Medical and Dental University (TMDU) and Niigata University identified a novel mechanism by which tumors progress. (2020-10-01)
Flexible and biodegradable electronic blood vessels
Researchers in China and Switzerland have developed electronic blood vessels that can be actively tuned to address subtle changes in the body after implantation. (2020-10-01)
Cancer cells use nerve-cell tricks to spread from one organ to the next
New research suggests that breast and lung tumors metastasize by hijacking a neural signaling pathway, potentially opening the door to better diagnostics and treatments. (2020-09-30)
Metal-ion breakthrough leads to new biomaterials
Metals such as iron and calcium play a crucial role inside the human body, so it's no surprise that bioengineers would like to integrate them into the soft, stretchy materials used to repair skin, blood vessels, lungs and other tissue. (2020-09-30)
Prototype graft, designed to replace damaged heart vessels, shows promise in cell study
North Carolina State University researchers reported promising preclinical findings for a prototype of a vascular graft designed as a replacement for a damaged or blocked coronary artery, which supplies blood to the heart. (2020-09-29)
Unconventional T cell subset enriched in airways of some patients with severe COVID-19
Unconventional T cells called mucosa-associated invariant T (MAIT) cells are recruited to the airways and strongly activated in some patients with severe COVID-19, a new study has found, suggesting the cells' possible involvement in the development of disease. (2020-09-28)
New potential treatment approach for patients with salt sensitive hypertension
A new study from Boston University School of Medicine (BUSM) has found that an alpha adrenoceptor blocker (a class of drugs that relaxes smooth muscle or blood vessels) may represent a new treatment approach for patients with salt sensitive hypertension. (2020-09-28)
Highly detailed map of the human heart could guide personalized heart treatments
Scientists have created a detailed cellular and molecular map of the healthy human heart to understand how this vital organ functions and to shed light on what goes awry in cardiovascular disease. (2020-09-24)
A study could provide guideline for exercise training aimed at high blood pressure patient
Brazilian researchers' finding that exercising in the evening reduces blood pressure more than in the morning can help health professionals choose the time of day for aerobic training depending on the type of anti-hypertensive drug they take. (2020-09-24)
Grappling with questions about how COVID-19 can affect the heart
For an issue once expected to occur mostly in patients with severe COVID-19, heart conditions following SARS-CoV-2 infection are much more prevalent, writes Eric Topol in a Perspective. (2020-09-23)
Blood vessel growth in muscle is reduced in women after menopause
A new study from the University of Copenhagen's Department of Nutrition, Exercise and Sports demonstrates that formation of small blood vessels is impaired in the muscle tissue of postmenopausal women. (2020-09-22)
Exercise before menopause is important to optimise health in later years
The small blood vessels in muscles of women after menopause are less able to grow compared to young women, according to new research published today in the Journal of Physiology. (2020-09-22)
Children who take steroids at increased risk for diabetes, high blood pressure, blood clots
Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers. (2020-09-17)
Live imaging method brings structural information to mapping of brain function
Neuroscientists distinguish brain regions based on what they do, but now have a new way to overlay information about how they are built, too. (2020-09-17)
Why the dose matters: Study shows levels and anti-tumor effectiveness of a common drug vary widely
When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients. (2020-09-17)
Super-potent blood stem cells discovered in human embryos
In research recently published in Stem Cell Reports, Andrejs Ivanovs, Alexander Medvinsky (a.medvinsky@ed.ac.uk) and colleagues from the University of Edinburgh discovered that HSCs from early human embryos, when HSCs are just starting to form, are more robust at expanding than those from the cord blood. (2020-09-17)
Stroke scans could reveal COVID-19 infection
New research from King's College London has found that COVID-19 may be diagnosed on the same emergency scans intended to diagnose stroke. (2020-09-17)
University of Cincinnati research produces different results from key China COVID-19 study
Early in the onset of the COVID-19 pandemic, a small study in China produced results that influenced subsequent research on the virus. (2020-09-17)
Generation of three-dimensional heart organoids
Researchers from Tokyo Medical and Dental University (TMDU) engineered three-dimensional functional heart organoids resembling the developing heart. (2020-09-16)
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