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Current Bone marrow News and Events

Current Bone marrow News and Events, Bone marrow News Articles.
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Soy foods linked to fewer fractures in younger breast cancer survivors
A new paper in JNCI Cancer Spectrum, published by Oxford University Press, is the first study to find that diets high in soy foods are associated with a decreased risk of osteoporotic bone fractures in pre-menopausal breast cancer survivors. (2019-05-21)
Zebrafish help researchers explore alternatives to bone marrow donation
UC San Diego researchers discover new role for epidermal growth factor receptor in blood stem cell development, a crucial key to being able to generate them in the laboratory, and circumvent the need for bone marrow donation. (2019-05-20)
Scientists capture first-ever video of body's safety test for t-cells
For the first time, immunologists have captured on video what happens when T-cells undergo a type of assassin-training program before they get unleashed in the body. (2019-05-17)
Archaeological discovery upends a piece of Barbados history
Which came first, the pigs or the pioneers? In Barbados, that has been a historical mystery ever since the first English colonists arrived in 1627 to encounter what they thought was a herd of wild European pigs. (2019-05-16)
3D-printed 'hyperelastic bone' may help generate new bone for skull reconstruction
Defects of the skull and facial bones can pose difficult challenges for plastic and reconstructive surgeons. (2019-05-16)
What do they mean by 'stem cells'? Recommended guidelines for reporting on cell therapies
Cell therapies including so-called 'stem cells' are increasingly being marketed and used for the treatment of musculoskeletal disorders -- despite questions about these treatments and their effectiveness. (2019-05-16)
Preclinical study: Probiotic-derived molecule may suppress fatal brain inflammation
The existence of certain microorganisms in your gut may bolster the immune system's ability to fend off a herpes viral attack that can cause fatal brain inflammation. (2019-05-14)
WVU researcher studies incurable blood disease usually diagnosed in children
Most people with Fanconi anemia are diagnosed before they turn 12 but don't live past 30. (2019-05-13)
Bone cells suppress cancer metastases
A subpopulation of bone cells releases factors that can halt the growth of breast cancer that's traveled to the bone, putting the cells in stasis. (2019-05-13)
Reviews highlight new advances in our understanding of focal and sclerotic bone diseases
A new special edition of 'Calcified Tissue International' provides expert commentary and insight into the advances in the knowledge of several rare focal and sclerotic bone diseases including Paget's disease of bone and related syndromes, fibrous dysplasia of bone and McCune-Albright syndrome, Melorheostosis and Osteopoikilosis, chronic non-bacterial osteomyelitis, as well as Camurati-Engelmann disease. (2019-05-13)
Fracture risk tool useful in women with breast cancer initiating aromatase inhibitor therapy
The FRAX® tool takes into account certain factors to determine the risk of bone fracture in the general population. (2019-05-09)
A link between mitochondrial damage and osteoporosis
In healthy people, a tightly controlled process balances out the activity of osteoblasts, which build bone, and osteoclasts, which break it down. (2019-05-09)
Stem cells make more 'cargo' packets to carry cellular aging therapies
Johns Hopkins scientists report that adult cells reprogrammed to become primitive stem cells, called induced pluripotent stem cells (iPSCs), make tiny 'cargo packets' able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells. (2019-05-07)
Making the invisible visible: New method opens unexplored realms for liquid biopsies
A new approach to RNA sequencing reveals thousands of previously inaccessible RNA fragments in blood plasma that might serve as disease- and organ-specific biomarkers (2019-05-03)
Messenger cells bring good news for bone healing, USC stem cell study finds
How do bones heal, and how could they heal better? (2019-05-03)
Biomarker may predict if immunotherapy is right choice for colorectal cancer patients
Foundational research could help metastatic colorectal cancer patients decide whether to choose immunotherapy or chemotherapy as a first treatment option. (2019-05-02)
Many stroke patients not screened for osteoporosis, despite known risks
Many stroke survivors have an increased risk of osteoporosis, falls or breaks when compared to healthy people. (2019-04-25)
Researchers reveal key to targeting dormant cancer cells
Researchers have identified what keeps some cancer cells dormant -- a finding which could uncover new approaches to preventing the spread of cancer. (2019-04-25)
Study of tagraxofusp reports 90% response rate for deadly blood cancer with no prior available therapies
An open-label, multi-cohort Phase II trial, led by investigators at the University of Texas MD Anderson Cancer Center, reports that treatment with the drug tagraxofusp resulted in high response rates in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare but highly aggressive -- and often fatal bone marrow and blood disorder -- for which there are no existing approved therapies. (2019-04-24)
Scientists define the role for a rare, influential set of bone marrow cells
Researchers have defined the roles of various cells in the bone marrow that are thought to control the fate of the nearly half million blood cells that develop there each day. (2019-04-23)
Overlooked molecular machine in cell nucleus may hold key to treating aggressive leukemia
Many people fighting a very aggressive form of acute myeloid leukemia (AML) don't survive more than five years. (2019-04-22)
The Leukemia Atlas: researchers unveil proteins that signal disease
Only about one in four people diagnosed with acute myelogenous leukemia (AML) survive five years after the initial diagnosis. (2019-04-17)
Princeton scientists discover an interaction that helps cancers spread to bone
A Princeton-led team of researchers have discovered a factor that promotes the spread of cancers to bone, opening the way toward treatments that could mitigate cancer's ability to colonize bone. (2019-04-15)
Stem Cell trial for osteoarthritis patients reduces pain, improves quality of life
In the first North American stem cell clinical trial for osteoarthritis of the knee patients, 12 patients were given injections of their own stem cells and followed for 12 months. (2019-04-12)
USC research shows remedy for painful jaw disease
USC researchers and collaborators report a breakthrough to prevent osteonecrosis of the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis. (2019-04-11)
Immune cells fighting blood cancer visualized for the first time
When cancer escapes the immune system, our defenses are rendered powerless and are unable to fight against the disease. (2019-04-08)
Dentists underdiagnose when faced with time pressure, research shows
Dentists can miss important details on X-rays when put under time pressure, according to new research led by the University of Plymouth. (2019-04-05)
Can human breast milk reduce intestinal injury following bone marrow transplant?
A new pilot study compared the use of human breast milk to formula in children less than five years of age who underwent bone marrow transplant, measuring the levels of inflammatory and pro-inflammatory biomarkers in the stool and blood to assess inflammatory injury to the intestinal microbiome. (2019-04-04)
Transplanted bone marrow endothelial progenitor cells delay ALS disease progression
Transplanting human bone marrow-derived endothelial progenitor cells into mice mimicking symptoms of amyotrophic lateral sclerosis (ALS) helped more motor neurons survive and slowed disease progression by repairing damage to the blood-spinal cord barrier, University of South Florida researchers report. (2019-04-02)
Targeted drug for leukemia tested at Penn Medicine helps patients live longer
An inhibitor drug that targets a specific mutation in relapsed or refractory acute myeloid leukemia (AML) helps patients live almost twice as long as those who receive chemotherapy. (2019-04-01)
Researchers discover how tumor-killing immune cells attack lymphomas in living mice
In a study that will be published April 1 in the Journal of Experimental Medicine, researchers from the Institut Pasteur and INSERM reveal that chimeric antigen receptor (CAR) T cells can induce tumor regression by directly targeting and killing cancer cells, uncovering new details of how these immune cells work and how their effectiveness could be improved in the treatment of non-Hodgkin's lymphoma and other B cell cancers. (2019-04-01)
HER2-targeted CAR T-cell therapy shows promising antitumor activity in patients with sarcoma
A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2 was found to be safe and showed clinical responses in pediatric and adult patients with advanced HER2-positive sarcoma, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-03-31)
3D printed tissues may keep athletes in action
Bioscientists at Rice and the University of Maryland with the Center for Engineering Complex Tissues learn to 3D-print scaffolds that may help heal osteochondral injuries of the sort suffered by many athletes. (2019-03-28)
Researchers at Dana-Farber/Boston Children's optimize gene editing for SCD and beta thalassemia
Gene editing of patients' blood stem cells can potentially cure many blood disorders. (2019-03-28)
New medication gives mice bigger muscles
Researchers from Aarhus University, Denmark, have studied a new group of medicinal products which increase the muscle- and bone mass of mice over a few weeks. (2019-03-27)
Osteoblastic cell stimulation by pulsed electromagnetic fields
Bone fracture healing can be augmented with the application of pulsed electromagnetic fields (PEMFs), but a consensus regarding idealized conditions is lacking. (2019-03-27)
Southern Europeans, non-Europeans less likely to have matched stem cell donors
Although the pool of registered bone marrow donors has increased in recent years, a new study suggests that most people of southern-European and non-European descent are unlikely to have a suitable match if they need a life-saving bone marrow transplant. (2019-03-27)
Walking downhill after meals boosts bone health in postmenopausal women with diabetes
Walking downhill after eating can reduce bone resorption, the process in which old bone is broken down and removed from the body, in postmenopausal women with diabetes, according to research to be presented Sunday, March 24, at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La. (2019-03-25)
Breast cancer may be likelier to spread to bone with nighttime dim-light exposure
Exposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers have shown for the first time in an animal study. (2019-03-23)
Bisphosphonates increasingly prescribed to the women most likely to benefit
In recent years, women who start taking bisphosphonates (BPs) to treat osteoporosis and prevent fracture have trended from younger to older and from having osteopenia to having osteoporosis, researchers report. (2019-03-23)
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