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Current Breast cancer News and Events

Current Breast cancer News and Events, Breast cancer News Articles.
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Indigenous American ancestry may be associated with HER2-positive breast cancer
An increased proportion of Indigenous American (IA) ancestry was associated with a greater incidence of HER2-positive breast cancer, according to a study published in Cancer Research, a journal of the American Association for Cancer Research. (2020-04-03)
Breast density, microcalcifications, and masses may be heritable traits
An analysis of a large Swedish cohort revealed that breast density, microcalcifications, and masses are heritable features, and that breast density and microcalcifications were positively associated with a genetic predisposition to breast cancer, according to a study published in Cancer Research, a journal of the American Association for Cancer Research. (2020-04-02)
Lung cancer surgery: Better survival probabilities with a higher case volume
In the surgical treatment of lung carcinoma, the more frequent performance of such interventions has a positive effect on treatment results -- the survival probabilities increase. (2020-04-02)
Ex­tra­cel­lu­lar forces help epi­thelial cells stick to­gether
Defects in the maintenance of the superficial tissue of the body, known as epithelial tissue, can help cancer cells achieve motility and metastasise. (2020-04-02)
Tailoring an anti-cancer drug for optimal tumor cell killing
Canadian biochemists identify distinguishing features that govern the potency of a class of anti-cancer compounds known as PARP inhibitors. (2020-04-02)
COPD linked to heightened risk of lung cancer in people who have never smoked
COPD, short for chronic obstructive pulmonary disease, is linked to a heightened risk of lung cancer in people who have never smoked, indicates research published online in the journal Thorax. (2020-04-02)
Androgen receptor stops tumor growth in the most common form of breast cancer
Researchers say they have found a viable new therapeutic strategy for estrogen receptor-positive (ER+) breast cancer, even cancers that are resistant to current standard of care treatments. (2020-03-31)
Cancer research, the guardian of the genome has a new ally
They identified a protein that, like a switch, controls the onset of cell death processes in cancer cells, which are regulated by p53, the protein known as 'the guardian of the genome.' The findings will be used to develop more tailored and effective cancer treatments. (2020-03-31)
Cancer treatment with immune checkpoint inhibitors may lead to thyroid dysfunction
Thyroid dysfunction following cancer treatment with new treatments called immune checkpoint inhibitors is more common than previously thought, according to research that was accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society. (2020-03-31)
Blood test accurately detects over 50 types of cancer, often before symptoms show
Researchers have developed the first blood test that can accurately detect more than 50 types of cancer and identify in which tissue the cancer originated, often before there are any signs of the disease. (2020-03-30)
Blood test detects wide range of cancers, available to at risk individuals in clinical study
In a study involving thousands of participants, a new blood test detected more than 50 types of cancer as well as their location within the body with a high degree of accuracy, according to an international team of researchers led by Dana-Farber Cancer Institute. (2020-03-30)
Studies confirm breast surgery health benefits
New studies highlighting the chronic health burden of oversized breasts outline the long-term benefits of breast reduction surgery to health, levels of wellbeing, and quality of life. (2020-03-29)
Disasters can affect cervical cancer screening for years
Screening is important for the early detection of cervical cancer, but rates were significantly affected, in some areas for years, following a devastating earthquake and tsunami in Japan. (2020-03-27)
Experiments in mice and human cells shed light on best way to deliver nanoparticle therapy for cancer
Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively -- allowing the nanoparticles to diffuse into tumors and become held in place, or actively -- adding a targeted anti-cancer molecule to bind to specific cancer cell receptors and, in theory, keep the nanoparticle in the tumor longer. (2020-03-26)
Trastuzumab deruxtecan shows early promise in patients with non-breast/gastric cancers
A HER2-targeted antibody-drug conjugate, fam-trastuzumab deruxtecan-nxki (Enhertu), showed signs of clinical activity in multiple non-breast/non-gastric cancer types, according to results from a phase I study. (2020-03-25)
Cellular protein shredders for the fight against cancer
An international team of researchers led by the Universities of Bonn and Ulm has investigated how a cell's own 'protein shredder' can be specifically programmed to fight cancer. (2020-03-25)
Engineers model mutations causing drug resistance
Whether it is a drug-resistant strain of bacteria, or cancer cells that no longer react to the drugs intended to kill them, diverse mutations make cells resistant to chemicals, and 'second generation' approaches are needed. (2020-03-24)
Seeing is believing: Visualizing differences in RNA biology between single cells
Researchers from the University of Tsukuba developed the novel and publicly available computational tool Millefy to visualize heterogeneity in RNA biology between single cells. (2020-03-23)
Interactions between cancer cells and fibroblasts promote metastasis
In order to colonize other organs and grow into metastases, tumor cells that detach from the parent tumor need to manipulate their new microenvironment and create a 'metastatic niche'. (2020-03-23)
NYU Abu Dhabi researchers develop new tool for performing cancer liquid biopsies
Cancer is a leading cause of death worldwide. When caught in its early stages, before metastasis (which is the growth of a secondary tumor separate to the primary site of cancer), it is known that cancer survival rates are higher. (2020-03-23)
Cancer patients over 65, on multiple medicines, are at higher risk of hospitalization
Older patients with prostate, breast, or lung cancer are more likely to be hospitalized after chemotherapy if they take more than five other medicines. (2020-03-20)
Device could 'hear' disease through structures housing cells
Researchers have built a device that uses sound waves to detect the stiffness of an extracellular matrix, a structural network that contains cells. (2020-03-20)
A protein that helps trap bacteria may contribute to metastasis in breast cancer
The protein peptidyl arginine deiminase 4 (PAD4), which enables some immune cells to trap bacteria, promoted breast cancer metastasis in mice when expressed in cancer cells, according to data published in Molecular Cancer Research, a journal of the American Association for Cancer Research. (2020-03-19)
Statins may protect against the heart harms of breast cancer therapies
Statins are widely used to lower cholesterol and prevent heart disease and related deaths, but can they also help guard against heart damage caused by certain breast cancer therapies? (2020-03-19)
New contrast agent for early diagnosis of brain metastases
A group of researchers led by Leif Schroeder from the Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie (FMP) have found a way to detect metastases in certain types of cancer in the brain at an early stage, using only minimal amounts of contrast agent. (2020-03-19)
Melanoma is killing fewest Americans in decades
Advances in treatment have led to the largest yearly declines in deaths due to melanoma ever recorded for this skin cancer, results of a new study suggest. (2020-03-19)
Certain cancers come with higher risk of serious heart rhythm disorder
People with a history of cancer have an over two-fold risk of developing atrial fibrillation (AFib), the most common heart rhythm disorder, compared to the general population, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-18)
Oncotarget Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy
The cover for issue 11 of Oncotarget features Figure 6, 'Effects of AZD8186 in combination with anti-PD1 on syngeneic models,' by Owusu-Brackett, et al. (2020-03-18)
Selective killing of cancer cells by cluttering their waste disposal system
Mixed-charge nanoparticles assemble into crystals and cause the death of thirteen types of cancer lines. (2020-03-16)
App detects harsh side effect of breast cancer treatment
Many breast cancer survivors suffer from lymph collection known as lymphedema. (2020-03-16)
Breast milk may help prevent sepsis in preemies
Researchers at Washington University School of Medicine in St. Louis and Mayo Clinic in Rochester, Minn., have found -- in newborn mice -- that a component of breast milk may help protect premature babies from developing life-threatening sepsis. (2020-03-16)
Oncotarget: MicroRNA (miR) dysregulation during Helicobacter pylori-induced gastric
Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells. (2020-03-13)
Statins starve cancer cells to death
More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. (2020-03-12)
Careless cancer cells may be susceptible to future drugs
Could the ability of cancer cells to quickly alter their genome be used as a weapon against malignant tumors? (2020-03-11)
Gasdermin E: A new approach to cancer immunotherapy that could have broad reach
Tumors have various ways of dodging attacks by the immune system. (2020-03-11)
Experimental drug combination shows potential for triple-negative breast cancer
Researchers from Vanderbilt-Ingram Cancer Center discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation. (2020-03-11)
Cancer cells spread using a copper-binding protein
Researchers at Chalmers University of Technology, Sweden, have shown that the Atox1 protein, found in breast cancer cells, participates in the process by which cancer cells metastasise. (2020-03-10)
Tomosynthesis outperforms digital mammography in five-year study
A new study has found that the advantages of digital breast tomosynthesis (DBT) over digital mammography (DM), including increased cancer detection and fewer false positive findings, are maintained over multiple years and rounds of screening. (2020-03-10)
Intralipid improves efficacy of chemotherapy treatment
Pairing chemotherapy nanodrugs with a nutritional supplement can lessen devastating side-effects while reducing the amount of the expensive drugs needed to treat cancer according to a study from Carnegie Mellon University and Taiwan's National Health Research Institutes. (2020-03-10)
Older women with breast cancer may benefit from genetic testing, study suggests
About 1 in 40 postmenopausal women diagnosed with breast cancer before age 65 have cancer-associated mutations in their BRCA1 or BRCA2 genes, according to a Stanford-led study of more than 4,500 participants in the long-running Women's Health Initiative. (2020-03-10)
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