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Current Cancer cells News and Events

Current Cancer cells News and Events, Cancer cells News Articles.
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Missing BAP1 gene associated with immunosuppressive molecules in uveal melanoma
New study from researchers in Finland and the United Kingdom reveals that tumors lacking a protein called BAP1 have an ineffective immune reaction against cancer, thus rendering immunotherapies ineffectual, particularly in uveal melanomas (UM). (2020-04-09)
Moffitt mathematical model predicts patient outcomes to adaptive therapy
In an article published in Nature Communications, Moffitt Cancer Center researchers provide a closer look at a mathematical model and data showing that individual patient alterations in the prostate-specific antigen (PSA) biomarker early in cancer treatment can predict outcomes to later treatment cycles of adaptive therapy. (2020-04-09)
Identical mice, different gut bacteria, different levels of cancer
Some types of gut bacteria are better than others at stimulating certain immune cells, specifically CD8+ T cells. (2020-04-09)
Knowledge of cancer diagnosis may affect survival
In a Psycho-Oncology study of adults in China with lung cancer, patients who knew of their cancer diagnosis generally survived longer than those who did not. (2020-04-08)
Researchers successfully repair stroke-damaged rat brains
Researchers at Lund University in Sweden have succeeded in restoring mobility and sensation of touch in stroke-afflicted rats by reprogramming human skin cells to become nerve cells, which were then transplanted into the rats' brains. (2020-04-08)
Cancer mutation in dual role
Researchers show that an oncogenic mutation in leukemia cells also promotes inflammations in the body (2020-04-08)
Drug shows promise in reversing kidney damage caused by lupus
A drug used for cancer therapy has shown promise in reversing kidney damage caused by systemic lupus erythematosus (SLE, or lupus), according to a Yale-led study published April 8 in the journal Science Translational Medicine. (2020-04-08)
Pancreatic cancer blocked by disrupting cellular pH balance
Scientists at Sanford Burnham Prebys have found a new way to kill pancreatic cancer cells by disrupting their pH equilibrium. (2020-04-07)
Lymphoma's different route revealed
Researchers at the MDC observe the very early stages of blood vessel development in lymph node tumors. (2020-04-07)
Cancer scientists at Purdue aim to use protein power to stop tumor growth
Purdue University scientists have created a new therapy option that may help halt tumor growth in certain cancers such as prostate, which is among the most common types of cancer in men. (2020-04-07)
Virginia Tech scientists reveal brain tumors impact normally helpful cells
Unprovoked recurrent seizures are a serious problem affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. (2020-04-06)
Hereditary mutation that drives aggressive head and neck, and lung cancers in Asians
New research from the Cancer Science Institute of Singapore at the National University of Singapore revealed a genetic variant in a gene called MET that is responsible for more aggressive growth of head and neck, and lung cancers in Asian populations. (2020-04-06)
Immunotherapy prior to surgery is effective in colon cancer
Patients with colon cancer, but no distant metastases, can benefit from a short course of immunotherapy while waiting for their surgery, as it can cause tumours to shrink substantially or clear up in a very short time. (2020-04-06)
Turning colon cancer cells around
Using a modified natural substance along with current approaches could improve colon cancer treatment, according to findings by University of California, Irvine biologists. (2020-04-03)
Ex­tra­cel­lu­lar forces help epi­thelial cells stick to­gether
Defects in the maintenance of the superficial tissue of the body, known as epithelial tissue, can help cancer cells achieve motility and metastasise. (2020-04-02)
Tailoring an anti-cancer drug for optimal tumor cell killing
Canadian biochemists identify distinguishing features that govern the potency of a class of anti-cancer compounds known as PARP inhibitors. (2020-04-02)
Colorado study overturns 'snapshot' model of cell cycle in use since 1974
Live, single-cell imaging shows cellular 'memory' of growth factor availability throughout the cell cycle (and not just snapshot of growth factor availability) influences cells' decision to replicate. (2020-04-02)
Starving pancreatic cancer of cysteine may kill tumor cells
In a new study of mice, Columbia researchers have found that an experimental drug that breaks down the amino acid cysteine slows pancreatic tumor growth by causing ferroptosis, an unusual form of cell death. (2020-04-02)
COPD linked to heightened risk of lung cancer in people who have never smoked
COPD, short for chronic obstructive pulmonary disease, is linked to a heightened risk of lung cancer in people who have never smoked, indicates research published online in the journal Thorax. (2020-04-02)
Daughter cells carry memory from mother on decision to divide
Researchers at CU Boulder have found that it's actually the mother cell that determines if its daughter cells will divide. (2020-04-02)
Majority of patients responded in CAR T-cell trial for mantle cell lymphoma
Majority of patients responded in CAR T-cell trial for mantle cell lymphoma. (2020-04-01)
Androgen receptor stops tumor growth in the most common form of breast cancer
Researchers say they have found a viable new therapeutic strategy for estrogen receptor-positive (ER+) breast cancer, even cancers that are resistant to current standard of care treatments. (2020-03-31)
Virtual cell predicts how close tumor environment influences cancer metastasis
IGC Researchers identify signals emitted by the tumor environment, which controls the migrating capacity of cancer cells. (2020-03-31)
Cancer research, the guardian of the genome has a new ally
They identified a protein that, like a switch, controls the onset of cell death processes in cancer cells, which are regulated by p53, the protein known as 'the guardian of the genome.' The findings will be used to develop more tailored and effective cancer treatments. (2020-03-31)
Novel cell-based cancer immunotherapy shows promise in early studies
Scientists have developed a new immunotherapy that eradicates solid tumours in mice without adverse side effects, according to a new study published today in eLife. (2020-03-31)
Cancer treatment with immune checkpoint inhibitors may lead to thyroid dysfunction
Thyroid dysfunction following cancer treatment with new treatments called immune checkpoint inhibitors is more common than previously thought, according to research that was accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society. (2020-03-31)
Scientists modify CAR-T cells to target multiple sites on leukemia cells
In a preclinical study, scientists engineer new CAR-T cells to attack three sites on leukemia cells, instead of one. (2020-03-31)
New therapeutic strategies proposed for some lung and kidney cancers
New therapeutic strategies proposed for some lung and kidney cancers. (2020-03-30)
Researchers discover potential boost to immunotherapy
Mount Sinai researchers have discovered a pathway that regulates special immune system cells in lung cancer tumors, suppressing them and allowing tumors to grow. (2020-03-30)
Biological 'atlas' shows dual personality for immune cells that cause Type 1 diabetes
Scientists at St. Jude Children's Research Hospital mapped the epigenetic controls on T cells, which could aid Type 1 diabetes diagnosis and treatment, as well as cancer immunotherapy. (2020-03-30)
Blood test detects wide range of cancers, available to at risk individuals in clinical study
In a study involving thousands of participants, a new blood test detected more than 50 types of cancer as well as their location within the body with a high degree of accuracy, according to an international team of researchers led by Dana-Farber Cancer Institute. (2020-03-30)
Disasters can affect cervical cancer screening for years
Screening is important for the early detection of cervical cancer, but rates were significantly affected, in some areas for years, following a devastating earthquake and tsunami in Japan. (2020-03-27)
New drug could reverse treatment resistance in advanced multiple myeloma
Researchers at the VU University Medical Center in the Netherlands have tested a new drug in patient samples and mice with multiple myeloma and discovered that it was effective even in advanced disease -- a point when many patients currently run out of options. (2020-03-27)
Oncotarget Characterization of iPS87, a prostate cancer stem cell-like cell line
Oncotarget Volume 11, Issue 12 reported outside its natural niche, the cultured prostate cancer stem cells lost their tumor-inducing capability and stem cell marker expression after approximately 8 transfers at a 1:3 split ratio. (2020-03-27)
Experiments in mice and human cells shed light on best way to deliver nanoparticle therapy for cancer
Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively -- allowing the nanoparticles to diffuse into tumors and become held in place, or actively -- adding a targeted anti-cancer molecule to bind to specific cancer cell receptors and, in theory, keep the nanoparticle in the tumor longer. (2020-03-26)
Insights into the diagnosis and treatment brain cancer in children
In a recent study published in Autophagy, researchers at Kanazawa University show how abnormalities in a gene called TPR can lead to pediatric brain cancer. (2020-03-26)
New 'more effective' stem cell transplant method could aid blood cancer patients
Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults. (2020-03-26)
New type of immunotherapy hinders the spread of ovarian cancer
Malignant ovarian cancer is insidious: Known and feared for vague and uncharacteristic symptoms that often mean the disease is discovered so late that on average only four out of six patients are still alive after five years. (2020-03-26)
Experimental medication to prevent heart disease may treat chemo-resistant ovarian cancer
Study shows CPT1A may help ovarian cancer cells spread, also resist chemo. (2020-03-26)
Moffitt researchers discover novel role of specific histone deacetylase in lung cancer
Researchers at Moffitt Cancer Center are trying to identify alternative strategies to treat non-small cell lung cancer (NSCLC). (2020-03-26)
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