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Computational 'match game' identifies potential antibiotics
Computational biologists at Carnegie Mellon University have devised a software tool that can play a high-speed 'Match Game' to identify bioactive molecules and the microbial genes that produce them so they can be evaluated as possible antibiotics and other therapeutic agents. (2019-10-16)
Election 2019: Hope for a national pharmacare plan
The 2019 federal election in Canada brings hope for universal pharmacare if Canadians ensure the elected government delivers on the long-delayed promise of universal access to essential medications, argues an editorial in CMAJ (Canadian Medical Association Journal). (2019-10-15)
Being attractive helps, but it isn't everything
Political scientist Sebastian Jäckle studies the influence of candidates' appearance on their electoral chances. (2019-10-15)
One third of patients with severe asthma are taking harmful doses of oral steroids
A third of patients with severe asthma are taking harmful doses of oral steroids, according to a study of several thousand people in The Netherlands, presented at the European Respiratory Society International Congress. (2019-10-01)
From primordial black holes new clues to dark matter
Moving through cosmic forests and spider webs in deep space in search of answers on the origin of the Cosmos. (2019-09-17)
Some cancer drugs in clinical trials don't work by hitting their targets
Multiple cancer drug candidates in clinical trials kill tumor cells through off-target effects instead of by interacting with their intended molecular targets, according to a new study. (2019-09-11)
Study: Children are interested in politics but need better education from parents and schools
The 2020 election is approaching -- how should we talk with children about this election and about politics more broadly? (2019-09-10)
Many who die waiting for a kidney had multiple offers, new study finds
Most patients who died or were removed from the kidney transplant waitlist before getting a transplant received multiple offers for a donor kidney. (2019-08-30)
Hiring committees that don't believe in gender bias promote fewer women
Is gender bias in hiring really a thing? Opinions vary, but a new study by a UBC psychologist and researchers in France reveals that hiring committees who denied it's a problem were less likely to promote women. (2019-08-26)
Dyslexia could affect pass rates in UK GP clinical skills exam
Trainee doctors who have dyslexia, and who declare this prior to taking the clinical skills component of the licensing exam for general practice, are less likely to pass than their counterparts, new research has shown. (2019-08-22)
Political campaigns may influence acceptance of violence against women
Nicole Johnson, assistant professor of counseling psychology at Lehigh University, set out to examine the influence, both positive and negative, of presidential campaigns, voting behavior, and candidate selection, on social views of rape culture. (2019-08-15)
Voters really want presidential candidates to talk more about science
A large majority of Iowans (74 percent) say it is important for the presidential candidates to talk about how science and scientific research will affect their policymaking decisions, but only 22 percent recall them discussing science issues during the past two months. (2019-08-02)
A novel graphene-matrix-assisted stabilization method will help unique 2D materials to become a part
Scientists from Russia and Japan found a way of stabilizing two-dimensional copper oxide (CuO) materials by using graphene. (2019-08-01)
Technological developments in radiation detectors enhance global nuclear security
Nuclear power plants can withstand most inclement weather and do not emit harmful greenhouse gases. (2019-07-30)
When considering presidential candidates, age is just a number
A new white paper shows there is no such thing as being too old to be president. (2019-07-26)
Artificial intelligence solution improves clinical trial recruitment
Clinical trials are a critical tool for getting new treatments to people who need them, but research shows that difficulty finding the right volunteer subjects can undermine the effectiveness of these studies. (2019-07-24)
From the Oscars to the Nobel Prize, winners need to choose their friends wisely
Being friends with an award juror can increase a person's chance of being nominated but decrease their chances of being selected as the victor, according to new research published in the Academy of Management Journal. (2019-07-12)
Two new algorithms can identify patients at risk of HIV
Two new studies developed algorithms that can identify patients who are at risk of acquiring HIV and may benefit from preventive care. (2019-07-08)
Study: Internet perpetuates job market inequality
Recent research finds the internet is giving employers and job seekers access to more information, but has not made the hiring process more meritocratic. (2019-06-26)
Reversing t cells' misunderstood rep in responding to a pediatric leukemia
A study of pediatric patients with leukemia demonstrates that they were able to generate T cells against tumor-associated mutations, contradicting previous assumptions that T cells cannot be effectively unleashed on pediatric tumors. (2019-06-26)
Adding clinical variables improves accuracy of lung allocation score
Implemented in 2005, the lung allocation score is used to prioritize patients awaiting lung transplants in the US. (2019-06-25)
Study shows visual framing by media in debates affects public perception
New research shows that in the 2016 primary debates the front runners from both parties benefitted from preferential visual treatment by the media, but Donald Trump won in terms of camera time and angle. (2019-06-24)
Reconfigurable multi-organ-on-a-chip system reliably evaluates chemotherapy toxicity
Christopher McAleer and colleagues have created a new multiorgan-on-a-chip system that can accurately capture the toxic effects of chemotherapies that have been metabolized by the liver -- effects usually not seen in standard cell culture preclinical drug development. (2019-06-19)
Study offers comprehensive roadmap for regulating political activity by nonprofits
Lloyd Hitoshi Mayer's comprehensive approach yields surprising and controversial solutions, beginning with the creation of a simple and broad definition of political activity that charities will be prohibited from engaging in. (2019-06-05)
Finding a needle in a haystack: Discovery of Ti 2 InB 2 for synthesizing layered TiB
Scientists at Tokyo Tech managed to use boron as the X element in a family of materials called MAX phases, for which only carbon and nitrogen could previously be used. (2019-05-31)
Data science helps engineers discover new materials for solar cells and LEDs
UC San Diego engineers have developed a high-throughput computational method to design new materials for next generation solar cells and LEDs. (2019-05-22)
Patients who lose significant weight before a transplant are at higher risk of dying
Unexpected weight loss can be the sign of a serious health problem, especially in kidney transplant patients whose body systems are already under duress. (2019-05-21)
New method simplifies the search for protein receptor complexes, speeding drug development
A a new method of assessing the actions of medicines by matching them to their unique protein receptors has the potential to greatly accelerate drug development and diminish the number of drug trials that fail during clinical trials. (2019-05-20)
Early in vitro testing for adverse effects on embryos
ETH researchers have combined embryonic cells and liver cells in a new cell culture test. (2019-05-14)
Women's leadership potential for top jobs overlooked in favor of men
The potential of women for leadership roles is being overlooked, while men benefit from the perception that they will grow into the role, new research from the University of Kent shows. (2019-05-14)
Alzheimer therapy from Jülich passes another important test
The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. (2019-05-13)
In mice, fast-acting compounds accelerate treatment of tropical parasitic worms
Two compounds, from among 300,000 candidates screened, kill parasite-supporting bacteria after a single dose in mouse models of filarial diseases -- one of the biggest contributors to disability and poverty in the developing world. (2019-05-08)
New computational tool improves gene identification
Looking to improve the identification of genes associates with disease, a team led by researchers at Baylor College of Medicine has developed a new bioinformatics tool that analyzes CRISPR pooled screen data and identifies candidates for potentially relevant genes with greater sensitivity and accuracy than other existing methods. (2019-05-06)
Underwater forests a treasure trove of new drugs
Defensive compounds produced by microbes are a major source of antibiotics and other important medicines. (2019-04-09)
Breakthrough in knowledge of how some sarcomas arise
The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. (2019-04-08)
Research into tropical eye worm yields new tests to assess safety of anti-filarial drugs
Researchers at the LSTM's Centre for Drugs and Diagnostics, and University of Buea, Cameroon have developed new models of the tropical eye worm, Loa loa for the development of new drugs against filariasis. (2019-03-29)
Social media has remarkably small impact on Americans' beliefs
Social media had only a small influence on how much people believed falsehoods about candidates and issues in the last two presidential elections, a pair of new national studies found. (2019-03-27)
Women are 30 percent less likely to be considered for a hiring process than men
Women are on average 30% less likely to be called for a job interview than men with the same characteristics. (2019-03-25)
Two for the price of one: Mechanistic insights lead to drug repositioning
A University of Tsukuba-led team confirmed that the binding of the cancer-promoting protein stratifin to phosphorylated SKP1 prevents the formation of a ubiquitinating enzyme complex. (2019-03-07)
Computer-designed vaccine elicits potent antibodies against RSV
A first-of-its-kind nanoparticle vaccine candidate for respiratory syncytial virus, a major cause of infant mortality worldwide, has been developed through computer design. (2019-03-07)
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