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From the Oscars to the Nobel Prize, winners need to choose their friends wisely
Being friends with an award juror can increase a person's chance of being nominated but decrease their chances of being selected as the victor, according to new research published in the Academy of Management Journal. (2019-07-12)
Two new algorithms can identify patients at risk of HIV
Two new studies developed algorithms that can identify patients who are at risk of acquiring HIV and may benefit from preventive care. (2019-07-08)
Study: Internet perpetuates job market inequality
Recent research finds the internet is giving employers and job seekers access to more information, but has not made the hiring process more meritocratic. (2019-06-26)
Reversing t cells' misunderstood rep in responding to a pediatric leukemia
A study of pediatric patients with leukemia demonstrates that they were able to generate T cells against tumor-associated mutations, contradicting previous assumptions that T cells cannot be effectively unleashed on pediatric tumors. (2019-06-26)
Adding clinical variables improves accuracy of lung allocation score
Implemented in 2005, the lung allocation score is used to prioritize patients awaiting lung transplants in the US. (2019-06-25)
Study shows visual framing by media in debates affects public perception
New research shows that in the 2016 primary debates the front runners from both parties benefitted from preferential visual treatment by the media, but Donald Trump won in terms of camera time and angle. (2019-06-24)
Reconfigurable multi-organ-on-a-chip system reliably evaluates chemotherapy toxicity
Christopher McAleer and colleagues have created a new multiorgan-on-a-chip system that can accurately capture the toxic effects of chemotherapies that have been metabolized by the liver -- effects usually not seen in standard cell culture preclinical drug development. (2019-06-19)
Study offers comprehensive roadmap for regulating political activity by nonprofits
Lloyd Hitoshi Mayer's comprehensive approach yields surprising and controversial solutions, beginning with the creation of a simple and broad definition of political activity that charities will be prohibited from engaging in. (2019-06-05)
Finding a needle in a haystack: Discovery of Ti 2 InB 2 for synthesizing layered TiB
Scientists at Tokyo Tech managed to use boron as the X element in a family of materials called MAX phases, for which only carbon and nitrogen could previously be used. (2019-05-31)
Data science helps engineers discover new materials for solar cells and LEDs
UC San Diego engineers have developed a high-throughput computational method to design new materials for next generation solar cells and LEDs. (2019-05-22)
Patients who lose significant weight before a transplant are at higher risk of dying
Unexpected weight loss can be the sign of a serious health problem, especially in kidney transplant patients whose body systems are already under duress. (2019-05-21)
New method simplifies the search for protein receptor complexes, speeding drug development
A a new method of assessing the actions of medicines by matching them to their unique protein receptors has the potential to greatly accelerate drug development and diminish the number of drug trials that fail during clinical trials. (2019-05-20)
Early in vitro testing for adverse effects on embryos
ETH researchers have combined embryonic cells and liver cells in a new cell culture test. (2019-05-14)
Women's leadership potential for top jobs overlooked in favor of men
The potential of women for leadership roles is being overlooked, while men benefit from the perception that they will grow into the role, new research from the University of Kent shows. (2019-05-14)
Alzheimer therapy from Jülich passes another important test
The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. (2019-05-13)
In mice, fast-acting compounds accelerate treatment of tropical parasitic worms
Two compounds, from among 300,000 candidates screened, kill parasite-supporting bacteria after a single dose in mouse models of filarial diseases -- one of the biggest contributors to disability and poverty in the developing world. (2019-05-08)
New computational tool improves gene identification
Looking to improve the identification of genes associates with disease, a team led by researchers at Baylor College of Medicine has developed a new bioinformatics tool that analyzes CRISPR pooled screen data and identifies candidates for potentially relevant genes with greater sensitivity and accuracy than other existing methods. (2019-05-06)
Underwater forests a treasure trove of new drugs
Defensive compounds produced by microbes are a major source of antibiotics and other important medicines. (2019-04-09)
Breakthrough in knowledge of how some sarcomas arise
The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. (2019-04-08)
Research into tropical eye worm yields new tests to assess safety of anti-filarial drugs
Researchers at the LSTM's Centre for Drugs and Diagnostics, and University of Buea, Cameroon have developed new models of the tropical eye worm, Loa loa for the development of new drugs against filariasis. (2019-03-29)
Social media has remarkably small impact on Americans' beliefs
Social media had only a small influence on how much people believed falsehoods about candidates and issues in the last two presidential elections, a pair of new national studies found. (2019-03-27)
Women are 30 percent less likely to be considered for a hiring process than men
Women are on average 30% less likely to be called for a job interview than men with the same characteristics. (2019-03-25)
Two for the price of one: Mechanistic insights lead to drug repositioning
A University of Tsukuba-led team confirmed that the binding of the cancer-promoting protein stratifin to phosphorylated SKP1 prevents the formation of a ubiquitinating enzyme complex. (2019-03-07)
Computer-designed vaccine elicits potent antibodies against RSV
A first-of-its-kind nanoparticle vaccine candidate for respiratory syncytial virus, a major cause of infant mortality worldwide, has been developed through computer design. (2019-03-07)
Scientists use machine learning to identify high-performing solar materials
Thanks to a study that combines the power of supercomputing with data science and experimental methods, researchers at the U.S. (2019-03-04)
Doctor-affiliated PACs fund political candidates who oppose firearm safety policies
Researchers found that physician-affiliated political action committees provided more financial support to candidates who opposed increased background checks, contrary to many societies' recommendations for evidence-based policies to reduce firearm injuries. (2019-02-22)
First study to find digital ads work, on millennials
'This is first time we found that digital ads do something and what they do is they increase voter turnout among millennials in municipal elections.' said Haenschen. (2019-01-30)
Why liver transplant waitlists might misclassify high-risk patients
A new study in the journal Gastroenterology reveals that the standard method for ranking patients on the waitlist for lifesaving liver transplantation may not prioritize some of the sickest candidates for the top of the list. (2019-01-24)
Fewer medical tests -- timely listing for transplantation
Younger patients would benefit greatly from kidney transplantation. Their expected remaining lifetime may even be doubled by having a transplant. (2019-01-22)
Democratic governors have bold ideas to transform health care: Harvard researchers
Republican and Democratic governors have strikingly different visions for the future of health care, according to a new analysis published in the American Journal of Public Health. (2019-01-16)
Nebraska leads $11 million study to develop radiation exposure drugs
Academic and medical researchers at the University of Nebraska are partnering with the Department of Defense to develop drug compounds that protect against and treat radiation exposure. (2019-01-14)
Selection and reselection processes of executive political positions are gender biased
Although male over-representation in politics is a worldwide phenomenon, the executive is the most male-dominated branch. (2019-01-11)
Would you vote for a Democrat who behaves like a Republican?
The Bright Line Watch team tested how committed the American public really is to its democracy. (2019-01-07)
Flavonoids as P-gp inhibitors: A systematic review of SARs
This review concerned the recent updates on the structure-activity relationships of flavonoids as P-gp inhibitors, the molecular mechanisms of their action and their ability to overcome P-gp-mediated MDR in preclinical studies. (2018-12-26)
First-of-its-kind study finds loss of local media worsens political polarization
Changes to the media environment have increased polarized voting in America through both addition and subtraction. (2018-11-20)
Insect antibiotic provides new way to eliminate bacteria
An antibiotic called thanatin attacks the way the outer membrane of Gram-negative bacteria is built. (2018-11-15)
New methods to identify Alzheimer's drug candidates with anti-aging properties
Old age is the greatest risk factor for many diseases, including Alzheimer's disease (AD) and cancer. (2018-11-13)
Researchers closer to gonorrhea vaccine after exhaustive analysis of proteins
In a study of proteins historic in its scope, researchers have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs. (2018-11-08)
Donor hearts at increased disease risk offer better survival rates for transplant recipients
Accepting an organ that has an increased risk of potentially transmitting disease offers a higher one-year survival rate for candidates on the heart transplant list over waiting for an organ with less risk, according to a study published today in the Journal of the American College of Cardiology. (2018-10-29)
Accelerating drug discovery by crowdsourcing confidential data
Leveraging modern cryptographic and machine learning tools, researchers seeking to accelerate drug discovery have developed a way for multiple pharmaceutical companies and laboratories to collaborate without revealing confidential data. (2018-10-18)
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