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Current Chemotherapy News and Events

Current Chemotherapy News and Events, Chemotherapy News Articles.
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IDIBELL -- ICO researchers set new bases to develop therapies against colorectal cancer
IDIBELL -- ICO researchers in Barcelona have found that inactivation of two proteins make tumoral cells more sensitive to chemotherapy. (2019-04-17)
Key protein a possible new target in the treatment of pancreatic cancer
Pancreatic Cancer Collective-funded research (Lustgarten Foundation and Stand Up To Cancer) from Dr. (2019-04-17)
Triple negative breast cancers can adopt reversible state that is resistant to chemotherapy
Researchers at The University of Texas MD Anderson Cancer Center have discovered that triple negative breast cancer (TNBC) cells can develop resistance to frontline, or neoadjuvant, chemotherapy not by acquiring permanent adaptations, but rather transiently turning on molecular pathways that protect the cells. (2019-04-17)
Some patients with imminently fatal cancer still receive treatment
Patients who died within one month of being newly diagnosed with metastatic cancer in the United States received ineffective surgery, chemotherapy, radiation, and hormonal therapy. (2019-04-15)
The FASEB Journal: New strategy to reduce cancer drug's cardiotoxic effects
Doxorubicin (Doxo) is a widely used chemotherapeutic drug for cancer, though it can have toxic effects on the heart. (2019-04-11)
Lung cancer treatments vary among the Asian communities
A study from the University of Southern California, Keck School of Medicine, sought to examine possible health disparities in the treatment of lung cancer within the Asian community in the US. (2019-04-09)
SWOG cancer research network study opens window into immune microenviroment
The first comprehensive study of immune cell types in pre- and post-chemotherapy cancer tissues points up a host of targets for new or existing cancer drugs that could improve patients' sensitivity to both chemotherapy and immunotherapy. (2019-04-09)
Cancer drug shortages result in almost no treatment changes, USC study finds
For the vast majority of cancer drugs experiencing shortages over a seven-year period, a new USC research study found no statistically significant effect of shortages on chemotherapy treatment. (2019-04-08)
Mayo Clinic finds 3 factors extend life for advanced pancreatic cancer patients
Historically, most pancreatic cancer patients whose tumors grow outside the pancreas to encompass veins and arteries have been told the cancer is inoperable and they should prepare for an average survival time of 12 to 18 months. (2019-04-02)
PARP inhibitors can shrink tumors in pancreatic cancer patients with specific mutations
Switching pancreatic cancer patients to the PARP inhibitor rucaparib as maintenance therapy may represent new treatment paradigm for pancreatic cancer patients with BRCA mutations. (2019-04-02)
Surgery associated with increased survival for patients with HER2+ stage 4 breast cancer
Surgery was associated with higher survival rates for patients with HER2-positive (HER2+) stage 4 breast cancer compared with those who did not undergo surgery, according to results presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-02)
Maintenance therapy with rucaparib shows clinical responses in a subgroup of patient with pancreatic cancer
Maintenance treatment with the PARP inhibitor rucaparib (Rubraca) was well tolerated and provided clinical responses among patients with advanced BRCA- or PALB2-mutated pancreatic cancer sensitive to platinum-based chemotherapy, according to results from an interim analysis of an ongoing phase II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-02)
Tumor microenvironment analyzed to increase effectiveness of preclinical trials
It was shown that co-culturing HeLa adenocarcinoma cells, peripheral blood mononuclear cells, and mesenchymal stromal cells results in changes in the proliferative activity of the peripheral blood mononuclear cells and mesenchymal stromal cell populations. (2019-04-02)
New role for a driver of metastatic cancers
Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. (2019-04-02)
Targeted drug for leukemia tested at Penn Medicine helps patients live longer
An inhibitor drug that targets a specific mutation in relapsed or refractory acute myeloid leukemia (AML) helps patients live almost twice as long as those who receive chemotherapy. (2019-04-01)
Gilteritinib improved survival for patients with acute myeloid leukemia
Treatment with the FLT3-targeted therapeutic gilteritinib (Xospata) improved survival for patients with relapsed or refractory acute myeloid leukemia (AML) harboring a FLT3 mutation compared with standard chemotherapy regimens, according to results from the ADMIRAL phase III clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-01)
HER2-targeted CAR T-cell therapy shows promising antitumor activity in patients with sarcoma
A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2 was found to be safe and showed clinical responses in pediatric and adult patients with advanced HER2-positive sarcoma, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-03-31)
Researchers target metastasis in fight against cancer
An experimental combination drug therapy attacking the DNA integrity of cancer cells is showing promise for a possible new cancer therapy in the future. (2019-03-28)
Tumor-associated immune cells hinder frontline chemotherapy drug in pancreatic cancer
A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of Michigan Rogel Cancer Center found. (2019-03-26)
Topical immunotherapy keeps skin cancer risk at bay
A combination of two topical creams already shown to clear precancerous skin lesions from sun-damaged skin also lowers the risk that patients will later develop squamous cell carcinoma of the skin. (2019-03-21)
New drug combination shows promise for common pediatric brain tumor
A new combination treatment aimed at resistant and recurrent low-grade gliomas slowed tumor growth and killed tumor cells in laboratory and mouse models. (2019-03-21)
Researchers use radiomics to predict who will benefit from chemotherapy
Using data from computed tomography (CT) images, researchers may be able to predict which lung cancer patients will respond to chemotherapy, according to a new study. (2019-03-20)
Stress hormones promote breast cancer metastasis
Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis with increased stress hormones. (2019-03-13)
Targeting stem-like cells could prevent ovarian cancer recurrence
A new drug takes out the 'seeds' that cause ovarian cancer to come back after chemotherapy. (2019-03-12)
Starving leukemia cells by targeting amino acids
Eliminating ASCT2 selectively stops the growth of leukemia cells, while having limited effects on healthy blood cells and hematopoetic (blood-forming) stem cells. (2019-03-12)
Adding docetaxel-based chemotherapy to standard treatment for high-risk prostate cancer
Researchers theorized that adding adjuvant docetaxel, a cytotoxic chemotherapy drug, to the standard of care RT and long-term AS treatment could potentially improve overall survival and clinical outcomes for men with localized, high-risk prostate cancer. (2019-03-12)
Imaging technique finds differences between radiation-sensitive and resistant tumors
Researchers have begun pilot clinical trials using an imaging technique called Raman spectroscopy, which offers promise for guided cancer treatment and could spare some patients of the toxic side effects of ineffective radiation therapy. (2019-03-11)
HIV remission achieved in second patient
A second person has experienced sustained remission from HIV-1 after ceasing treatment, reports a paper led by researchers at UCL and Imperial College London. (2019-03-05)
Researchers search for solutions to 'invisible threat' that affects cancer care workers
A study from the University of Michigan Rogel Cancer Center sought to improve nurses' handling of chemotherapy by delivering an educational intervention with quarterly reminders and tailored messages. (2019-03-01)
The importance of sex-specific strategies for prevention, treatment of heart failure in women
There are many important differences between women and men with heart failure, highlighting the importance of sex-specific strategies for prevention and treatment, according to three papers publishing today in JACC: Heart Failure. (2019-02-25)
For young adult cancer survivors, debt and work-related impairments
One of the largest-ever studies of work-related risks in young adult cancer survivors finds that of 872 survivors, 14.4 percent borrowed more than $10,000 and 1.5 percent said they or their family had filed for bankruptcy as a direct result of illness or treatment. (2019-02-25)
Sperm quality unaffected by one course of chemotherapy for early testicular cancer
Men with early stage testicular cancer can safely receive one course of chemotherapy or radiotherapy after surgery without it having a long-term effect on their sperm count, according to a study published in Annals of Oncology. (2019-02-24)
PET scans show biomarkers could spare some breast cancer patients from chemotherapy
In an effort to further individualize therapy and avoid over-treating patients, researchers at the Johns Hopkins Kimmel Cancer Center report a new study using PET scans has identified a biomarker that may accurately predict which patients with one type of HER2-positive breast cancer might best benefit from standalone HER2-targeted agents, without the need for standard chemotherapy. (2019-02-21)
New compound could help treat ovarian cancer
Scientists from the University of Sheffield have discovered a compound that could be more effective in treating certain cancers than standard chemotherapy. (2019-02-20)
New AI able to identify and predict the development of cancer symptom clusters
Cancer patients who undergo chemotherapy could soon benefit from a new AI that is able to identify and predict the development of different combinations of symptoms -- helping to alleviate much of the distress caused by their occurrence and severity. (2019-02-20)
Antibody-drug conjugate shows promise against metastatic triple-negative breast cancer
Treatment with the experimental drug sazituzumab govitecan produced a significant treatment response in patients with difficult-to-treat metastatic triple-negative breast cancer. (2019-02-20)
'Cellular barcoding' reveals how breast cancer spreads
A cutting-edge technique called cellular barcoding has been used to tag, track and pinpoint cells responsible for the spread of breast cancer from the main tumour into the blood and other organs. (2019-02-15)
Some primary care doctors not prepared to help with cancer treatment decisions
Research has shown patients are discussing initial cancer treatment options with their primary care doctors. (2019-02-12)
New drug brings unexpected hope in targeting cancer cells
An unexpected finding in preclinical platelet studies by Baker Institute researchers could provide a novel approach to targeting and destroying difficult-to-treat cancer cells, providing new therapeutic options for a range of cancers. (2019-02-08)
Therapy derived from parasitic worms downregulates proinflammatory pathways
A therapy derived from the eggs of parasitic worms helps to protect against one of chemotherapy's debilitating side effects by significantly downregulating major proinflammatory pathways, reducing inflammation. (2019-02-07)
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