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Current Chemotherapy News and Events

Current Chemotherapy News and Events, Chemotherapy News Articles.
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Technology shines the light on ovarian cancer treatments
A Purdue University scientist and entrepreneur is working to use simple LED light to help determine if certain chemotherapy options will work for specific patients. (2020-10-22)
Researchers develop a simplified method to modify disease signaling with light
Cellular optogenetics is a technique that allows researchers to use light to precisely control cell signaling and function in space and time enabling the investigation of mechanisms involved in disease processes. (2020-10-22)
New drug that can prevent the drug resistance and adverse effects
A research team in Korea is garnering attention for having developed an anticancer drug that could potentially prevent drug resistance. (2020-10-21)
Gut bacteria linked to weight gain following chemotherapy treatment for breast cancer
A new study suggests that gut bacteria are partially responsible for metabolic changes that lead to weight gain following chemotherapy treatment. (2020-10-21)
Oncotarget: quantitative ultrasound radiomics in prediction of treatment response for breast cancer
The cover for Issue 42 of Oncotarget features Figure 4, ''Generation of parametric and texture maps from radiofrequency data,'' recently published in ''Quantitative ultrasound radiomics using texture derivatives in prediction of treatment response to neo-adjuvant chemotherapy for locally advanced breast cancer'' by Dasgupta, et al. which reported that to investigate quantitative ultrasound based higher-order texture derivatives in predicting the response to neoadjuvant chemotherapy in patients with locally advanced breast cancer. (2020-10-21)
Calcium bursts kill drug-resistant tumor cells
Multidrug resistance (MDR) -- a process in which tumors become resistant to multiple medicines -- is the main cause of failure of cancer chemotherapy. (2020-10-16)
Experimental glioblastoma therapy shows curative powers in mice models
Houston Methodist researchers used a second-generation prodrug called MP-Pt(IV) to target the deadly cells of glioblastoma tumors and found mice harboring human glioblastoma tumors in their brains had greatly enhanced survival and weight gain when given the newly developed prodrug. (2020-10-08)
Colorectal cancer treatment: the winning combinations
Chemotherapy has distressing side effects for patients and increases the risk of developing resistance to the treatment. (2020-10-06)
Scientists propose immune cocktail therapy to boost cancer-immunity cycle in multiple aspects
A research team led by Prof. TIAN Huayu from the Changchun Institute of Applied Chemistry (CIAC) of the Chinese Academy of Sciences proposed an innovative immune cocktail therapy that combined ICT along with other therapeutic approaches. (2020-09-30)
Genetic test identifies invasive lobular carcinomas that are at high risk of recurring
New results to be presented at the 12th European Breast Cancer Conference show that a test, which looks at the activity of 70 genes in breast cancer tissue, is possible to use in the clinic to identify patients with invasive lobular carcinoma (ILC) that is at high risk of recurring and progressing. (2020-09-30)
Identified the cellular process by which Cisplatin chemotherapy causes neuronal damage
Cisplatin induces senescence of peripheral neurons through overexpression of the p21 protein, which would explain the neuropathy. (2020-09-29)
Researchers discover a new method to regulate cell plasticity
Researchers at IRB Barcelona's Cellular Plasticity and Disease Laboratory propose a more efficient way to limit cell plasticity without causing cell damage. (2020-09-28)
CNIO identifies genetic factors associated to hand-foot syndrome in chemotherapy with capecitabine
* The researchers studied more than 600,000 genetic variants in the genome of 166 patients treated with the chemotherapy drug capecitabine * Before undergoing treatment, the patients carrying the risk alleles for the hand-foot syndrome had low levels of two proteins that are key to the effective functioning of the skin barrier * The finding may help classify patients according to their genetic risk for developing this side effect of some cancer treatments (2020-09-21)
Immunotherapy improves survival in advanced bladder cancer patients
An immunotherapy drug called 'avelumab' has been shown to significantly improve survival in patients with the most common type of bladder cancer, according to results from a phase III clinical trial led by Queen Mary University of London and Barts Cancer Centre, UK. (2020-09-18)
PPIs may affect responses to atezolizumab in patients with urothelial cancer
Proton pump inhibitor (PPI) use was associated with worse outcomes in patients with urothelial cancer treated with the immunotherapeutic atezolizumab (Tecentriq), compared with patients who did not use PPIs. (2020-09-17)
Biomarker reveals how aggressive biliary tract cancer is in patients
Researchers from University of Copenhagen and Herlev and Gentofte Hospital have discovered a biomarker that might predict the course of the disease in patients with the rare and aggressive biliary tract cancer (BTC). (2020-09-15)
CU researchers now better understand ovarian cancer tumors and treatment outcomes
After nearly four years of work, a group of researchers and clinicians from CU published a paper this week in the Clinical Cancer Research that shares findings from research looking at how the composition of ovarian cancer tumors changes during chemotherapy and contributes to therapeutic response. (2020-09-15)
Cigarette smoking associated with worse outcomes for bladder cancer patients after surgery
Study from Keck Medicine of USC links smoking with a higher risk of death and cancer recurrence, and less responsiveness to chemotherapy. (2020-09-15)
The web of death
Cancer is one of the most frequent causes of death. (2020-09-10)
Combination immunotherapy benefits subset of patients with advanced prostate cancer
esults from a Phase II trial led by researchers at MD Anderson Cancer Center suggest that a combination of ipilimumab (anti-CTLA-4) plus nivolumab (anti-PD-1) can generate durable responses in a subset of patients with advanced prostate cancer. (2020-09-10)
Study finds botanical effective for chemo-resistant colon cancer
The natural botanical Andrographis paniculata, when given in conjunction with chemotherapy, may eventually change the way doctors treat chemotherapy-resistant colorectal cancer. (2020-09-09)
Phase 1 human trials suggest UIC-developed breast cancer drug is safe, effective
A new type of breast cancer drug can help halt progression of disease and is not toxic, according to phase 1 clinical trials. (2020-08-27)
Single-cell RNA sequencing sheds new light on cancer cells' varied response to chemotherapy
Single-cell analysis, done in three colon cancer cell lines, is believed to be the first to profile transcriptome-level changes in response to DNA damage across individual cells. (2020-08-25)
Cancer and its treatment may accelerate the aging process in young patients
A new study examines the effects of cancer and its treatment on the aging process. (2020-08-24)
Key molecule responsible for poor prognosis of breast cancer identified
Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer. (2020-08-21)
Mass General researchers create bioluminescent tag to detect DNA break repair
A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan. (2020-08-21)
Researchers discover how enzyme protects cells from DNA damage
A research team from Mount Sinai has unraveled for the first time the three-dimensional structure and mechanism of a complex enzyme that protects cells from constant DNA damage, opening the door to discovery of new therapeutics for the treatment of chemotherapy-resistant cancers. (2020-08-17)
How to get more cancer-fighting nanoparticles to where they are needed
University of Toronto Engineering researchers have discovered a dose threshold that greatly increases the delivery of cancer-fighting drugs into a tumour. (2020-08-10)
checkmate 743 shows that dual immunotherapy, nivolumab + ipilimumab
The combination of first-line nivolumab and ipilimumab demonstrated an improvement of overall survival for patients with unresectable malignant pleural mesothelioma compared to platinum-based chemotherapy, according to research presented today at the International Association for the Study of Lung Cancer Virtual Presidential Symposium. (2020-08-08)
Addition of sintilimab to pemetrexed and platinum improved progression-free survival
The interim analysis of ORIENT-11, a phase III double-blind randomized trial has shown a nearly two-fold increase in progression-free survival with addition of sintilimab to chemotherapy in patients with advanced or metastatic non-squamous non-small cell lung cancer without EGFR or ALK genomic aberrations, according to research data presented today at the International Association for the Study of Lung Cancer Virtual Presidential Symposium. (2020-08-08)
Chemotherapy for rare cancer fine-tuned with organoids
A patient-specific tumor organoid model developed at Wake Forest is being used to identify the most effective chemotherapy protocol to treat appendix and colon tumors, a personalized medicine approach that is showing promise. (2020-08-07)
Chemotherapy is used to treat less than 25% of people with localized sarcoma
UCLA researchers have found that chemotherapy is not commonly used when treating adults with localized sarcoma, a rare type of cancer of the soft tissues or bone. (2020-08-06)
The first mouse model of human pancreas cancer subtypes
Organoids power the first mouse model of two pancreas cancer subtypes, identifying genes influencing a lethal transformation of one subtype to the other. (2020-07-23)
New nano drug candidate kills aggressive breast cancer cells
Researchers at the University of Arkansas have developed a new drug candidate that kills triple negative breast cancer cells. (2020-07-20)
How to repair your gut
In a world first, Monash University researchers have identified a key biomolecule that enhances the repair of your gut lining by prompting stem cells to regenerate damaged tissue. (2020-07-20)
MU advances chemotherapy-free treatment for cancer in animals and humans
Osteosarcoma, a common bone cancer in dogs, affects more than 10,000 dogs in the US each year. (2020-07-17)
IU findings set new standard for blood-based biomarkers in prediction of cancer recurrence
Indiana University School of Medicine researchers Milan Radovich, PhD, and Bryan Schneider, MD, have discovered that the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in the plasma of women's blood who have undergone chemotherapy prior to surgery for the treatment of stage 1, 2 or 3 triple negative breast cancer are critical indicators for the prediction of disease recurrence and disease-free survival. (2020-07-09)
Early clinical trial tests treatment strategy for pancreatic cancer
Pancreatic cancer carries a poor prognosis, and it often goes undetected until advanced stages. (2020-07-08)
Enhancing chemotherapy by RNA interference - BIO Integration
Enhancing Chemotherapy by RNA Interference - BIO Integration https://doi.org/10.15212/bioi-2020-0003 Announcing a new article publication for BIO Integration journal. (2020-07-08)
Study: Surgical delay associated with increased risk in some gastrointestinal malignancies
Early in the COVID-19 pandemic, widespread cancellations of electively-scheduled or ''non-emergency'' operations were implemented to free up hospital beds and conserve protective equipment for health care workers. (2020-07-07)
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