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Current Chemotherapy News and Events

Current Chemotherapy News and Events, Chemotherapy News Articles.
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Findings could identify aggressive breast cancers that will respond to immunotherapy
UNC Lineberger researchers discovered a biological signature that could help identify which triple negative breast cancers might respond to immunotherapy and other treatments. (2019-11-14)
High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers
78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment. (2019-11-13)
ELeCt-ing a better candidate for chemo delivery
Chemo drugs are notoriously toxic, in part because so little of the drug actually gets to its target organ, requiring high doses. (2019-11-13)
The gut may be the ticket to reducing chemo's side effects
In a new study, scientists observed several simultaneous reactions in mice given a common chemotherapy drug: Their gut bacteria and tissue changed, their blood and brains showed signs of inflammation, and their behaviors suggested they were fatigued and cognitively impaired. (2019-11-11)
Tailor-made for older adults, new tools improve doctor-patient relations
A Wilmot Cancer Institute-led study in JAMA Oncology shows that when physicians fully appreciate the concerns of older adults with cancer, such as function and forgetfulness, it elevates patient care and satisfaction. (2019-11-07)
Analysis by surgical trainees examines recommendations for mastectomy across the UK
A woman's decision to undergo mastectomy for breast cancer relies on communication with her surgeon and, in addition, often draws on recommendations from a 'multidisciplinary team' (MDT) of doctors from different specialties such as oncology and radiology. (2019-11-06)
How sweet it isn't: Diminished taste function affects cancer patients' food intake
In a review of 11 studies 'that psychophysically measured taste and smell function and assessed some aspect of food behavior,' a University of Massachusetts Amherst sensory scientist found a reduced taste function, particularly for sweet flavors, among people with cancer. (2019-11-06)
Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain
Effective drug delivery through the BTB is one of the greatest therapeutic obstacles in treating brain metastases. (2019-10-31)
Researchers identify possible approach to block medulloblastoma growth
University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children. (2019-10-24)
A possible gut-brain connection to 'chemo brain'
To test the possible relationship between the gut and chemo brain, Leah Pyter's lab is examining chemo's effects on mice whose guts have been manipulated before treatment. (2019-10-23)
Regenstrief and IUPUI researchers use EHRs to identify cancer symptom clusters
Patients with chronic diseases such as cancer often experience fatigue, pain, depression and other symptoms which can lead to distress and functional impairment if left untreated. (2019-10-22)
New drug-delivery technology promises efficient, targeted cancer treatment
A precise and non-toxic treatment that targets lung cancer cells at the nanoscale is able to effectively kill the cells even at a low dose. (2019-10-22)
Researchers identify a new way to target treatment-resistant cancers
An international team of researchers has found a different way cancer becomes resistant to chemotherapy, suggesting a new target for drugs. (2019-10-21)
Patient-derived organoids help predict how patients respond to chemotherapy
Researchers have created a test based on tumor organoids -- or 3D tissue cultures -- that can help predict how patients with advanced colorectal cancer (CRC) may respond to chemotherapy treatment. (2019-10-09)
Hormone therapy has a bigger impact than chemotherapy on women's quality of life in bc
Contrary to the commonly held view, 2 years after diagnosis, hormone therapy, a highly effective breast cancer treatment worsens quality of life to a greater extent and for a longer time, especially in menopausal patients. (2019-10-08)
New evolution-busting drug overcomes resistance in aggressive breast cancers
A new type of drug that blocks one of cancer's key evolutionary escape routes from chemotherapy could be used to treat aggressive breast cancers, a new study has shown. (2019-10-05)
Engineered T cells may be harnessed to kill solid tumor cells
A new Tel Aviv University study finds that a form of immunotherapy used to treat the blood cancer leukemia may be effective in treating other kinds of cancer as well. (2019-10-02)
TAILORx: New data on cohort with recurrence score 26-100 shows 93% cancer-free rate at 5 years
In the prospective TAILORx trial, 93% of women with hormone-sensitive, HER2-negative, axillary node-negative breast cancer and a high Recurrence Score 26-100 were estimated to be cancer-free at five years. (2019-09-30)
Modern chemo better than second targeted hormone therapy against resistant prostate cancer
A modern chemotherapy drug is more effective for men with advanced prostate cancer than a second targeted hormone therapy in patients who have stopped responding to treatment, a major clinical trial shows. (2019-09-30)
New treatment improves survival in women newly diagnosed with advanced ovarian cancer
An international study shows that administering niraparib after chemotherapy reduces by nearly 40% the risk of relapse or death from this disease. (2019-09-28)
PARP inhibitor plus chemotherapy improves progression-free survival for advanced ovarian cancer patients
Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that initial treatment with the PARP inhibitor veliparib in combination with chemotherapy significantly increased progression-free survival (PFS) for patients with newly diagnosed, metastatic high-grade serous ovarian cancer, according to the results of the VELIA trial. (2019-09-28)
ECOG-ACRIN announces late-breaking TAILORx data at ESMO Congress 2019
The European Society for Medical Oncology (ESMO) 2019 Congress will present, and JAMA Oncology will concurrently publish, the clinical outcomes of a subset of women with early breast cancer who participated in TAILORx, the landmark breast cancer treatment trial. (2019-09-25)
Nanotechnology improves chemotherapy delivery
Michigan State University scientists have invented a new way to monitor chemotherapy concentrations, which is more effective in keeping patients' treatments within the crucial therapeutic window. (2019-09-25)
Pathway found for treatment-resistant lung cancer
A big way chemotherapy works is by prompting cancer cells to commit suicide, and scientists have found a pathway the most common lung cancer walks to avoid death. (2019-09-20)
Study finds new way to make chemotherapy more effective against pancreatic cancer
Pancreatic adenocarcinoma (PDAC) is a lethal malignancy that most often is resistant to chemotherapy. (2019-09-18)
Cancer cells turn to cannibalism to survive chemotherapy, study suggests
Researchers from the Tulane University School of Medicine have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. (2019-09-17)
Novel anti-cancer nanomedicine for efficient chemotherapy
Researchers have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. (2019-09-17)
Cosmetic changes are equivalent after WBI vs PBI for women with early stage breast cancer
Results from the Quality of Life substudy of the NRG Oncology clinical trial NSABP B-39/RTOG 0413 indicate that women rated post-lumpectomy partial breast irradiation (PBI) as equivalent to whole breast irradiation (WBI) in terms of cosmetic outcomes and satisfaction from baseline to three years following radiotherapy treatment. (2019-09-16)
Scientists discover new breakthrough in cancer hair loss treatment
Researchers based at The University of Manchester have discovered a new strategy for how to protect hair follicles from chemotherapy, which could lead to new treatments that prevent chemotherapy-induced hair loss -- arguably one of the most psychologically distressing side effects of modern cancer therapy. (2019-09-12)
Bone marrow may be the missing piece of the fertility puzzle
A woman's bone marrow may determine her ability to start and sustain a pregnancy, report Yale researchers in PLOS Biology. (2019-09-12)
Breaking the 'stalemate' in the most common soft tissue sarcoma in children
Rhabdomyosarcoma is the most common soft tissue sarcoma in children. (2019-09-12)
IMpower131
Patients with Stage IV squamous non-small cell lung cancer enrolled in clinical trial to test the immunotherapy atezolizumab and chemotherapy against chemotherapy alone experienced a longer survival rate, among a subgroup of patients with high PD-LI. (2019-09-10)
KEYNOTE-024 three-year survival update
First line pembrolizumab monotherapy provides durable long-term overall survival benefit compared to chemotherapy, according to data presented today by Dr. (2019-09-10)
Patients taking nivolumab experience five-fold increase in overall survival compared to chemotherapy
Pooled data on two clinical trials demonstrate patients taking nivolumab realized a greater than five-fold increase in five-year overall survival rate compared with the chemotherapy docetaxel. (2019-09-10)
Precious metal flecks could be catalyst for better cancer therapies
Tiny extracts of a precious metal used widely in industry could play a vital role in new cancer therapies. (2019-09-09)
New KEYNOTE 021 data shows no association with tumor mutational burden
Researchers had previously reported data from the KEYNOTE 021 trial that showed antitumor activity for pembrolizumab plus platinum-based chemotherapy in untreated advanced nonsquamous non-small cell lung cancer patients. (2019-09-08)
Keynote 189: Tumor mutational burden not significantly associated with efficacy of pembrolizumab
Tumor mutational burden was not significantly associated with efficacy of pembrolizumab plus chemotherapy or placebo plus chemotherapy as first-line therapy for metastatic nonsquamous non-small cell lung cancer, according to research reported today by Dr. (2019-09-08)
Role of cancer protein ARID1A at intersection of genome stability and tumor suppression
The ARID1A tumor suppressor protein is required to maintain telomere cohesion and correct chromosome segregation after DNA replication. (2019-09-06)
Discovered the potential of antihistamines that cause the death of leukaemic stem cells
The IJC Leukaemic Stem Cell research group, led by Ruth M. (2019-09-06)
FAK protein linked to chemotherapy resistance in ovarian cancer
A new University of California San Diego School of Medicine study links changes in the gene for the protein focal adhesion kinase, or FAK, to ovarian cancer's ability to survive chemotherapy. (2019-09-03)
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