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Current Chromosomes News and Events

Current Chromosomes News and Events, Chromosomes News Articles.
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Single mutation leads to big effects in autism-related gene
A new study in Neuron offers clues to why autism spectrum disorder (ASD) is more common in boys than in girls. (2020-04-02)
Sturgeon genome sequenced
Sturgeons lived on earth already 300 million years ago and yet their external appearance seems to have undergone very little change. (2020-03-30)
A critical enzyme for sperm formation could be a target for treating male infertility
Researchers led by Jeremy Wang of the University of Pennsylvania School of Veterinary Medicine have identified an enzyme essential for the process of male meiosis, the type of cell division that produces sperm. (2020-03-25)
Scientists reveal how proteins team up to repair DNA
Scientists have revealed an important mechanism in the repair of DNA double-strand breaks, according to new research published today in eLife. (2020-03-24)
Zigzag DNA
How the cell organizes DNA into tightly packed chromosomes. Nature publication by Delft University of Technology and EMBL Heidelberg. (2020-03-04)
New insights into evolution: Why genes appear to move around
Scientists at Uppsala University have proposed an addition to the theory of evolution that can explain how and why genes move on chromosomes. (2020-03-04)
Why do men -- and other male animals -- tend to die younger? It's all in the Y chromosome
Males of most animal species die earlier than females because their smaller Y chromosome is unable to protect an unhealthy X chromosome, research suggests. (2020-03-03)
GPS for chromosomes: Reorganization of the genome during development
The spatial arrangement of genetic material within the cell nucleus plays an important role in the development of an organism. (2020-02-28)
Male-killing bacteria linked to butterfly color changes
Like many poisonous animals, the African monarch butterfly's orange, white and black pattern warns predators that it is toxic. (2020-02-28)
Extra chromosomes in cancers can be good or bad
Extra copies of chromosomes are typical in cancerous tumor cells, but researchers taking a closer look find that some extra copies promote cancer growth while others actually inhibit cancer metastasis. (2020-02-24)
SR-FACT microscopy reveals the landscape of the cellular organelle interactome
We developed super-resolution fluorescence-assisted diffraction computational tomography(SR-FACT), which combines three-dimensional optical diffraction tomography with two-dimensional fluorescence Hessian structured illumination microscopy. (2020-02-17)
New research shows how the malaria parasite grows and multiplies
Scientists have made a major breakthrough in understanding how the parasite that causes malaria is able to multiply at such an alarming rate, which could be a vital clue in discovering how it has evolved, and how it can be stopped. (2020-02-11)
New repair mechanism for DNA breaks
Researchers from the University of Seville and the Andalusian Centre of Molecular Biology and Regenerative Medicine (CABIMER) have identified new factors that are necessary for the repair of these breaks. (2020-02-10)
Novel insight into chromosome 21 and its effect on Down syndrome
A UCL-led research team has, for the first time, identified specific regions of chromosome 21, which cause memory and decision-making problems in mice with Down syndrome, a finding that provides valuable new insight into the condition in humans. (2020-01-28)
Give & take: Cancer chromosomes give the game away
As tumours develop, cancer cells gain and lose so-called 'chromosome arms', changing their response to drugs, a finding which may offer better personalised treatments for 17 types of cancer. (2020-01-28)
Unique centromere type discovered in the European dodder
Commonly, the presence of histone variant CENH3 epigenetically determines the positioning of centromeres. (2020-01-27)
Researchers unlock secrets of cell division, define role for protein elevated in cancer
Researchers at Princeton University have successfully recreated a key process involved in cell division in a test tube, uncovering the vital role played by a protein that is elevated in over 25% of all cancers. (2020-01-14)
Common genetic defect in prostate cancer inspires path to new anti-cancer drugs
Researchers found that, in prostate cancer, a mutation leading to the loss of one allele of a tumor suppressor gene known as PPP2R2A is enough to worsen a tumor caused by other mutations. (2020-01-09)
Common plasticizer disrupts C. elegans egg production
A new study published Jan. 9 in PLOS Genetics by Mónica Colaiácovo of Harvard Medical School and colleagues reports that the most commonly used plasticizer, diethylhexyl phthalate (DEHP), leads to fertility problems by causing an excess number of breaks in the DNA during egg production, and then interfering with the repair systems that fixes the breaks. (2020-01-09)
Break point
Experiments in worms reveal the molecular damage caused by DEHP, a chemical commonly used to make plastics flexible. (2020-01-09)
The birds and the bees and the bearded dragons
Though sex itself is widespread among lifeforms, the mechanisms determining an individual's sex vary spectacularly across organisms. (2019-12-23)
Record-size sex chromosome found in two bird species
Researchers in Sweden and the UK have discovered the largest known avian sex chromosome. (2019-12-04)
New approach to treating incurable leukemia in children discovered
Acute lymphoblastic leukemia is the most common form of cancer affecting children in Switzerland and, unfortunately, is often incurable. (2019-11-25)
Spot the difference: Two identical-looking bird species with very different genes
While reports of species going extinct are sadly becoming common, an international team of scientists has identified a new species of bird living on the Southern coast of China, that diverged from their Northern relatives around half a million years ago. (2019-11-13)
Crick researchers unravel protective properties of telomere t-loops
Loops at the ends of telomeres play a vital protective role preventing irretrievable damage to chromosomes, according to new research from the Crick. (2019-11-13)
New tool facilitates genetic mapping of polyploid plants
Available online for free, polyploid mapping system developed in Brazil helps breeders of sugarcane, kiwi, blueberry, sweet potato and forages, among other crops. (2019-11-08)
Neural network fills in data gaps for spatial analysis of chromosomes
Computational methods used to fill in missing pixels in low-quality images or video also can help scientists provide missing information for how DNA is organized in the cell, computational biologists at Carnegie Mellon University have shown. (2019-11-07)
Complex cellular machine visualized to yield new insights in cancer
Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. (2019-10-31)
New organelle that helps prevent cancer discovered in our cells
Scientists have discovered a strange structure inside our cells that helps to prevent cancer by ensuring genetic material is sorted correctly as cells divide. (2019-10-22)
Defining the centromere
Centromeres are the chromosomal domains at which the kinetochore, a protein complex required for the correct separation of chromosomes during mitosis and meiosis, is assembled. (2019-10-21)
Genes linked to sex ratio and male fertility in mice
Michigan Medicine researchers find genes that help maintain the 50-50 balance between male and female offspring in mice--and that have major implications for male infertility. (2019-10-18)
Modern Melanesians harbor beneficial DNA from archaic hominins
Modern Melanesians harbor beneficial genetic variants that they inherited from archaic Neanderthal and Denisovan hominins, according to a new study. (2019-10-17)
X marks the spot: recombination in structurally distinct chromosomes
A recent study from the laboratory of Stowers Investigator Scott Hawley, PhD, has revealed more details about how the synaptonemal complex performs its job, including some surprising subtleties in function. (2019-10-16)
Buttons and flies help Hopkins solve longtime DNA mystery
Biologists at Johns Hopkins University have uncovered an important clue in the longtime mystery of how long strands of DNA fold up to squeeze into microscopic cells, with each pair of chromosomes aligned to ensure perfect development. (2019-10-10)
How chromosomes change their shape during cell differentiation
Scientists from the RIKEN Center for Biosystems Dynamics Research have provided an explanation of how chromosomes undergo structural changes during cell differentiation. (2019-10-09)
Researchers are finding molecular mechanisms behind women's biological clock
Throughout life, women's fertility curve goes up and down, and in a new study led by the University of Copenhagen, researchers have now shown why. (2019-10-09)
Breakthrough in sex-chromosome regulation
Researchers at Karolinska Institutet in Sweden have uncovered a chromosome-wide mechanism that keeps the gene expression of sex chromosomes in balance in our cells. (2019-10-03)
How newly found tension sensor plays integral role in aligned chromosome partitioning
A Waseda University-led research found that oncogene SET/TAF1, which was found to be a proto-oncogene of acute myeloid leukemia (AML), contributes to proper chromosome partitioning as a tension sensor. (2019-09-30)
Cancer: The origin of genetic mutations
In the presence of some disruptive elements, cancer cells are unable to replicate its DNA optimally. (2019-09-25)
Key similarities discovered between human and archaea chromosomes
A study led by Indiana University is the first to reveal key similarities between chromosomes in humans and archaea. (2019-09-19)
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