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Current Colorectal cancer News and Events

Current Colorectal cancer News and Events, Colorectal cancer News Articles.
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Counties with persistent poverty rates experience higher rates of cancer deaths
Residents of counties that experience persistent poverty face a disproportionately high risk of cancer mortality. (2020-09-30)
Breast cancer medication risk
New research led by Flinders University has found a link between beta-blockers and survival outcomes in some breast cancer patients. (2020-09-29)
Scientists kill cancer cells by 'shutting the door' to the nucleus
Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes--large channels that control the flow of materials in and out of the cell nucleus--shrank aggressive tumors in mice while leaving healthy cells unharmed. (2020-09-28)
Suicidality among adult survivors of childhood cancer
A recent study found that survivors of childhood cancer have a similar risk of having suicidal thoughts compared with other individuals, and they have lower risk of suicidal behaviors and suicidal death. (2020-09-23)
New insights into colorectal cancer: Growth factor R-spondin suppresses tumor growth
R-spondin, which enhances the growth of healthy cells in the gut, suppresses the growth of intestinal adenoma cells, thus reducing the formation of intestinal tumors. (2020-09-23)
CNIO identifies genetic factors associated to hand-foot syndrome in chemotherapy with capecitabine
* The researchers studied more than 600,000 genetic variants in the genome of 166 patients treated with the chemotherapy drug capecitabine * Before undergoing treatment, the patients carrying the risk alleles for the hand-foot syndrome had low levels of two proteins that are key to the effective functioning of the skin barrier * The finding may help classify patients according to their genetic risk for developing this side effect of some cancer treatments (2020-09-21)
KRAS inhibitor sotorasib appears safe, achieves durable clinical benefit in early trial
For patients with advanced solid cancers and KRAS G12C mutations, the targeted therapy sotorasib, a KRAS G12C inhibitor, resulted in manageable toxicities and durable clinical benefits, particularly in lung and colorectal cancer, in Phase I study. (2020-09-20)
Promising phase 1 trial results: Use of sotorasib (AMG 510) in patients with solid tumors
A phase 1 clinical trial of sotorasib (AMG 510) in patients with heavily pretreated advanced solid tumors shows encouraging anti-cancer activity, especially in lung and colorectal cancers, reports a new study led by City of Hope and other renowned comprehensive cancer centers. (2020-09-20)
Examining association of coffee consumption, survival in patients with colorectal cancer
Researchers in this observational study investigated the association between the number of cups of coffee consumed per day and survival in patients with advanced or metastatic colorectal cancer. (2020-09-17)
Coffee associated with improved survival in metastatic colorectal cancer patients
In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Dana-Farber Cancer Institute and other organizations report in a new study. (2020-09-17)
New study estimates nearly 90,000 cancer cases diagnosed in adolescents and young adults
A new report examining cancer in adolescents and young adults (AYAs), defined as diagnoses occurring during ages 15 to 39, provides updated estimates of the contemporary cancer burden in this age group, predicting that 89,500 cases and 9,270 deaths will occur in 2020 in the United States. (2020-09-17)
Reducing colorectal cancer disparities among African american men
Out of any other racial group, African American men have the lowest five-year survival rate for colorectal cancer (CRC). (2020-09-16)
Molecular basis underlying colorectal cancer revealed
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target. (2020-09-15)
University of South Carolina study reveals how cannabinoids may be useful to prevent colon cancer
Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are caused by inflammation of the gastrointestinal tract. (2020-09-15)
High-risk patients for colorectal cancer lack knowledge about colonoscopy
Many clinicians rely on self-reports from their high-risk patients about their need and proper interval for repeat surveillance colonoscopy. (2020-09-14)
Researchers develop rapid test for ovarian cancer detection
Researchers at the University of Turku, Finland, have developed a test for ovarian cancer detection with a sensitivity 4.5 times higher than that of the conventional laboratory test. (2020-09-11)
The web of death
Cancer is one of the most frequent causes of death. (2020-09-10)
Black people more likely than others to die from colorectal cancer spreading to the liver
Colorectal cancer is more prevalent among Black people, a group that has the highest rates of death for an illness that is curable if caught early. (2020-09-09)
Study finds botanical effective for chemo-resistant colon cancer
The natural botanical Andrographis paniculata, when given in conjunction with chemotherapy, may eventually change the way doctors treat chemotherapy-resistant colorectal cancer. (2020-09-09)
Protein causes mutations that lead to breast cancer cell aggression
In her previous research, University of Alberta biochemist Ing Swie Goping identified that the protein, BCL-2 interacting killer (BIK), was associated with relapses in breast cancer patients. (2020-09-08)
A new model to predict survival in colorectal cancer
This signature could be useful in clinical practice, especially for colorectal cancer diagnosis and therapy. (2020-09-03)
Men with larger waists more likely to die of prostate cancer
A study of more than 200,000 UK men, being presented at this year's European and International Conference on Obesity (ECOICO), held online this year from September 1-4, reveals that there is a link between central adiposity (concentration of body fat around the belly and waist) and the risk of death from prostate cancer. (2020-09-01)
Large study finds no link between blood pressure medication and cancer
There is no evidence that blood pressure lowering drugs increase the risk of cancer, according to the most extensive study conducted on the topic. (2020-08-31)
Immune protein IL-17A responsible for lethal side effects of gastric cancer
The formation of scar tissue, or fibrosis, as gastric cancer disseminates throughout the peritoneum can be more lethal than the cancer itself and can interfere with chemotherapy. (2020-08-26)
Oncotarget: Paradox breaker BRAF inhibitors in BRAF mutant colorectal cancer
Oncotarget Volume 11, Issue 34 features Figure 1, ''BRAF inhibitor-induced changes in cell viability,'' by Pickles, et which reported that the BEACON CRC trial demonstrated a survival advantage over chemotherapy for a combination of targeted agents comprising the potent BRAF inhibitor encorafenib together with cetuximab and binimetinib. (2020-08-25)
Small change makes cancer vaccine more effective in animal tests
Tweaking the adenovirus spike protein induces a more robust immune reaction for a cancer vaccine against gastric, pancreatic, esophageal and colon malignancies in animal models. (2020-08-24)
In one cancer therapy, two halves are safer than a whole
Splitting one type of cancer drug in half and delivering the pieces separately to cancer cells could reduce life-threatening side effects and protect healthy, non-cancerous cells, a new study suggests. (2020-08-24)
Key molecule responsible for poor prognosis of breast cancer identified
Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer. (2020-08-21)
Molecule secreted by cancer-associated fibroblasts promotes anticancer drug resistance
Joint research at Kumamoto University in Japan discovered a new mechanism for anticancer drug resistance in gastric cancer. (2020-08-21)
Genetic background influences disease risk from single-gene variants
Life can change dramatically when someone learns they are genetically predisposed to a disease. (2020-08-20)
Sortilin may hold the key to combat pancreatic cancer more effectively
Pancreatic cancer has an extremely poor prognosis; it is the third most common cause of cancer deaths in the United States. (2020-08-20)
Intestinal bacteriophage alters effects of cancer therapies in mice
Enterococcus, a genus that includes common commensal bacteria found in the gut, harbors a bacteriophage that influences the effects of various cancer immunotherapies in ways that may be clinically relevant, researchers working in mice report. (2020-08-20)
Current lung cancer public health screening guidelines under count African Americans
Public health screening guidelines for lung cancer followed by the United States Preventive Services Task Force (USPSTF) and the Center for Medicare and Medicaid Services (CMS) undercount African Americans, contributing to disparities in lung cancer screening and treatment, according to a study published today in the Journal of Thoracic Oncology. (2020-08-18)
568 genes identified with the potential to trigger cancer
Analysis of the genomes of 28,000 tumours from 66 types of cancer has led to the identification of 568 cancer driver genes Performed by the Biomedical Genomics Lab at IRB Barcelona, the study has allowed a major update of the Integrative OncoGenomics (IntOGen) platform, aimed at identifying mutational cancer driver genes. (2020-08-17)
Potency-enhancing drugs linked to decreased risks in men with colorectal cancer
A new study from Lund University and Region Skåne in Sweden indicates that potency-enhancing PDE5 inhibitor drugs have an anti-cancer potential with the ability to improve the prognosis in patients with colorectal cancer. (2020-08-17)
Regulation of cancer stemness by the best combination of nanotech and genetic engineering
Photo-active nanocomplexes are successfully developed. The nanocomplexes allow spatiotemporal controlling genetically-engineered cells that are overexpressing temperature-sensitive membrane proteins. (2020-08-17)
UCalgary researchers discover the microbiome's role in attacking cancerous tumours
University of Calgary researchers have discovered which gut bacteria help our immune system battle cancerous tumours and how they do it. (2020-08-13)
Smoking strongly linked to women's lower take up of cancer screening services
Smoking is strongly linked to lower use of cancer screening services by women, and more advanced disease once cancer is diagnosed, reveals research published in the online journal BMJ Open. (2020-08-13)
Unlocking how cellular proteins control cancer spread
A new insight into cell signals that control cancer growth and migration could help in the search for effective anti-cancer drugs. (2020-08-12)
Enzyme discovered in the gut could lead to new disease biomarker
Enzymes used by bacteria to break down mucus in the gut could provide a useful biomarker for intestinal diseases, according to new research published in Nature Communications. (2020-08-11)
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