Current Congenital heart disease News and Events

Current Congenital heart disease News and Events, Congenital heart disease News Articles.
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Less sedentary time reduces heart failure risk for older women
The more waking hours older women spend sitting or lying down, the more likely they are to require hospitalization for heart failure. The association between sedentary hours and heart failure was present in postmenopausal women with a variety of health conditions and strikingly, even among women who were active at guideline-recommended levels. (2020-11-24)

Scoring system improves screening for "dual" heart disease
Aortic stenosis is one of the most common heart valve defects. As well as conventional valve replacement involving open-heart surgery, a less invasive procedure has now been available for some time in the form of transcatheter aortic valve replacement (TAVR). (2020-11-24)

Act now to meet global heart disease targets
Cardiovascular disease remains the leading cause of mortality in Europe, and World Health Organization (WHO) heart disease goals will not be achieved by 2025 unless urgent action is taken. That is the finding of a European Society of Cardiology (ESC) report published today. 'Cardiovascular Realities 2020' is a compendium of the latest statistics on cardiovascular disease (CVD) in Europe. The document provides numbers of people with heart conditions, death rates, and levels of risk factors including obesity, diabetes, and high blood pressure. (2020-11-24)

Treatment shows reduction in heart failure after myocardial infarction
Researchers at Baylor College of Medicine identified potential preventative therapies for heart failure after a significant heart attack. (2020-11-24)

Hypertrophic cardiomyopathy guideline encourages shared decision-making
The American Heart Association and the American College of Cardiology today released an updated guideline for managing patients with hypertrophic cardiomyopathy (HCM). The guideline encourages shared decision-making between the clinician and patient as essential when determining treatment course and updates recommendations for sudden cardiac death (SCD) risk assessment and HCM center referrals based on the latest evidence. (2020-11-20)

A bypass route for the coronary vessels in the heart?
When the heart develops, some of its coronary blood vessels develop from cells lining the inner surface of the heart's ventricular chambers (endocardium). Novel findings suggest that new blood vessel growth in the heart can be stimulated with the VEGF-B growth factor from the same source after myocardial infarction to increase blood delivery to the damaged area. (2020-11-19)

A novel drug target for neonatal and infant heart failure
Researchers have identified a new druggable target for heart failure in neonates and infants. Approximately 60 percent of children born with congenital heart abnormalities will develop overt heart failure within the first year of life. The progression of heart failure in these infants is often rapid, with a high frequency of fatalities. Stimulation of this target significantly increased the cardiac contractility of newborns and infants in mice with few side effects. (2020-11-19)

Greater mosquito susceptibility to Zika virus fueled the epidemic
By experimentally comparing wild populations of Ae. aegypti the researchers discovered that the invasive subspecies is very effective at transmitting the Zika virus not only because it has more frequent contacts with humans for blood meals, but also as a result of its greater susceptibility to the virus relative to the African subspecies. (2020-11-19)

'Domestication' increases mosquito's zika virus susceptibility
The Aedes aegypti aegypti subspecies of mosquito, which has become a ''domestic'' pest worldwide, can acquire and transmit Zika virus more easily than its African forerunner. (2020-11-19)

Implantation of an S-ICD in a patient with a DDD pacemaker and congenitally corrected transposition
Implantation of an S-ICD in a Patient with a DDD Pacemaker and Congenitally Corrected Transposition of the Great Arteries. In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0597, Yu Zhang, Wen-Long Dai, Can-Can Lin, Qiao-Yuan Li and Cheng-Jun Guo from Beijing Anzhen Hospital, Capital Medical University, Beijing, China consider implantation of an S-ICD in a patient with a DDD pacemaker and congenitally corrected transposition of the great arteries. (2020-11-19)

A case of pediatric heart failure caused by anomalous origin of the left coronary artery from the pulmonary artery
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0585, Lei Zhang, Tiewei Lv, Xiaoyan Liu, Chuan Feng, Min Zheng, Jie Tian and Huichao Sun from the Children's Hospital of Chongqing Medical University, Chongqing, China and the Chongqing Key Laboratory of Pediatrics, Chongqing, China consider a case of pediatric heart failure caused by anomalous origin of the left coronary artery from the pulmonary artery. (2020-11-19)

Children with familial hypercholesterolemia are diagnosed late and under-treated
Children born with a common genetic condition, familial hypercholesterolemia (FH), are at increased risk for atherosclerotic cardiovascular disease (ASCVD) early in life. Despite long-standing national guidelines, cholesterol screening -- for children at age 2 for those with a family history of heart disease and between the ages of nine to 11 for all children -- is not being implemented . (2020-11-18)

Computer vision predicts congenital adrenal hyperplasia
Using computer vision, researchers have discovered strong correlations between facial morphology and congenital adrenal hyperplasia (CAH), a life-threatening genetic condition of the adrenal glands and one of the most common forms of adrenal insufficiency in children. The findings could have implications for phenotyping and treating patients with CAH. (2020-11-18)

Cellular pathway of genetic heart disease similar to neurodegenerative disease
Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. (2020-11-18)

New diabetes medication reduced heart event risk in those with diabetes and kidney disease
Sotagliflozin - a type of medication known as an SGLT2 inhibitor primarily prescribed for Type 2 diabetes - reduces the risk of adverse cardiovascular events for patients with diabetes and kidney disease. Researchers say the results of this randomized clinical trial provide evidence that SGLT2 inhibitors should be part of the standard of care for people with Type 2 diabetes and chronic kidney disease. (2020-11-17)

New medication helps heart health in people with chronic kidney disease, Type 2 diabetes
Results of a large, international clinical trial on the novel medication finerenone indicate it reduced the rate of death, heart attack, stroke and hospitalization for heart failure among patients with chronic kidney disease and Type 2 diabetes. Finerenone helped patients with chronic conditions improve their heart health, regardless of if they had a history of cardiovascular disease. (2020-11-17)

COVID-19 patient outcomes affected by cardiovascular risk
DALLAS - Nov. 17, 2020 - Research presented today by UT Southwestern cardiologists at the annual American Heart Association (AHA) Scientific Sessions 2020 showed that Black and Hispanic people were more likely to be hospitalized with COVID-19 than white patients, and that nonwhite men with cardiovascular disease or risk factors were more likely to die. (2020-11-17)

High-dose equal to standard flu vaccine for risk of death or heart, lung hospitalization
A high-dose, trivalent influenza vaccine was no more effective than the standard-dose quadrivalent vaccine at reducing the risk of death or hospitalization for heart or lung-related causes among patients with heart disease. While overall there were few serious side effects in both vaccine groups, those who received the high-dose vaccine had more injection-related side effects such as pain, swelling and muscle aches. (2020-11-17)

Blacks, Hispanics comprised more than half of all inpatient deaths from COVID-19
More than half of all in-hospital deaths due to COVID-19 during the first six months of 2020 were among Black and Hispanic patients, according to a new study led by researchers at the Stanford University School of Medicine and Duke University. (2020-11-17)

Healthy sleep habits help lower risk of heart failure
Healthy sleep habits are associated with a lower risk of heart failure. Adults with the healthiest sleep patterns (morning risers, sleeping 7-8 hours a day and no frequent insomnia, snoring or excessive daytime sleepiness) experienced a 42% reduction in the risk of heart failure compared to those with unhealthy sleep patterns. (2020-11-16)

Scientists discover new mechanism controlling brain size
International research headed by Danish Scientists has led to the discovery of a new mechanism that controls the size of our brains. The finding, which is based on studies on a rare congenital brain disease, delivers an important piece of data in our knowledge about how the human brain is formed during development. (2020-11-16)

Preventing heart disease should be a priority for people with Type 2 diabetes
Even when risk factors associated with cardiovascular disease are optimally controlled, adults with Type 2 diabetes still have a greater risk of developing cardiovascular disease compared to the general population, according to new research published today in the American Heart Association's flagship journal Circulation. (2020-11-16)

A change of heart -- new drug for HCM reduces heart mass
For the first time, a medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, hypertrophic cardiomyopathy, rather than simply addressing their symptoms. (2020-11-16)

Patients taking statins experience similar side effects from dummy pills
People taking dummy pills and statins experienced similar side effects in a new study. (2020-11-15)

STRENGTH trial finds new fish oil medication did not reduce the risk of cardiac events
A medication derived from fish oil, containing the omega-3 fatty acids EPA and DHA, was evaluated in a large, international study of more than 13,000 people who had existing heart disease or who were at high risk of heart disease due to other medical conditions. The medication did not reduce the risk of cardiac events compared to a corn oil-based placebo in the STRENGTH trial. (2020-11-15)

Additional heart imaging valuable for women with unexplained heart attacks
Combining diagnostic imaging methods can detect the underlying cause of heart attack in women who did not have blocked arteries. This international, diagnostic, prospective, observational study suggested that additional heart imaging is feasible and has the potential to guide medical therapy to prevent subsequent heart attacks. (2020-11-14)

New medicine reduced risk for heart failure emergencies, hospital visits
Results from a large, Phase 3, global, cardiovascular outcomes study indicate a new medication may reduce the risk for heart failure-related events or cardiovascular deaths in people with chronic heart failure. (2020-11-13)

New screening questionnaire can identify people at high risk of developing heart disease
A new study in a Swedish population of middle-aged adults found that four out of 10 people have atherosclerosis, a buildup of fatty deposits that reduce blood flow to the heart. Early detection of coronary artery disease is needed in order to provide preventive treatment and decrease the risk of heart attack. Researchers developed a personalized screening strategy to identify individuals with a higher probability of developing cardiovascular disease. (2020-11-13)

New study confirms combo pill alone and with aspirin lowers heart disease risk
A ''polypill'' is a single pill that includes multiple medications to control more than one health risk factor (such as heart disease, high blood pressure, high cholesterol, Type 2 diabetes, kidney disease, stroke). In this large, international trial, the polypill included blood pressure and cholesterol lowering medications for people at risk for heart disease. Results from the randomized, placebo-controlled trial show that the combination of a polypill plus aspirin reduced cardiovascular disease by 31%, and the polypill without aspirin reduced CVD by 21%. (2020-11-13)

Intravenous iron reduced rehospitalization risk in people with heart failure
Iron deficiency is present in about 50% of people with chronic heart failure. Patients with heart failure who also have iron-deficiency are more likely to have poor outcomes. Intravenous iron replacement with ferric carboxymaltose reduced the risk of heart failure hospitalizations in patients with iron deficiency after an episode of acute heart failure. (2020-11-13)

Study: Vitamin D, fish oil don't lower atrial fibrillation risk
New research presented today at the American Heart Association Scientific Sessions suggests neither vitamin D nor the omega-3 fatty acids found in fish oil prevent the development of atrial fibrillation, a potentially serious heart rhythm disturbance. (2020-11-13)

Not all patients with certain type of heart attack receive the same care
An analysis of medical records reveals variability in the tests and treatments that patients with type 2 myocardial infarction receive during and after their hospital stay. Clinical trials are needed to provide guidance to physicians on how to best care for these patients. (2020-11-11)

New source of lymphatic system leak discovered in children with rare open heart surgery complication
Interventional radiologists with Nemours Children's Health System have identified a new source of abnormal lymphatic flow between the liver and the lungs that may be responsible for some cases of plastic bronchitis. Plastic bronchitis is a rare but serious late complication in patients with congenital heart disease who had Fontan surgery. A report detailing the discovery of this fluid leak, and successful treatment of two cases was published in European Heart Journal. (2020-11-11)

Racial/ethnic minorities comprise small portion of patients referred with AL amyloidosis
Despite being theoretically at an increased risk for AL amyloidosis, underrepresented minorities make up only a small percentage of patients seen at specialized treatment centers for this disease. (2020-11-10)

Women veterans with PTSD have higher rate of heart disease
Women veterans with posttraumatic stress disorder (PTSD) were 44% more likely to develop ischemic heart disease including heart attacks, compared to those without PTSD. The increased risk was most prominent in younger women (below the age of 40). (2020-11-09)

U.S.-born Black women at higher risk of preeclampsia than Black immigrants
Black women born in the United States have a higher risk of developing high blood pressure during pregnancy, a condition known as preeclampsia, compared to Black women who immigrated to the country. In this study of Black women in Boston, those who were not born in the U.S. had a 27% lower risk of preeclampsia, compared to Black women born in America. The risk increased for Black immigrants after they lived in the U.S. for more than 10 years. (2020-11-09)

Flu vaccine rate less than 25% in young adults with heart disease, despite increased risk
In 2018, only about 25% of adults between the ages of 18 and 34 with any cardiovascular disease received a flu shot, and in those with a history of a heart attack, only about 20% were vaccinated. Study authors hope their results will increase awareness among cardiologists, primary care physicians and the public about the protective benefits of flu vaccination. (2020-11-09)

More green spaces can help boost air quality, reduce heart disease deaths
The number of trees, shrubs and grasses in an area - known as green space or greenness - can improve air quality, counteract air pollution and may reduce heart disease deaths. Policies that improve environmental factors also can improve cardiovascular health among a diverse population. (2020-11-09)

Many transgender people who receive hormone therapy have unaddressed heart disease risks
Many transgender people who receive gender-affirming hormone therapy have heart disease and stroke risk factors such as high blood pressure and cholesterol, even during young adulthood. Of those known to have CVD risk factors, many were not previously treated to lower their heart disease risk. (2020-11-09)

A novel finding on Kabuki syndrome, a rare genetic disease
It has a long time since the cause of the disease has been identified: mutations of KMT2D gene codify for MLL4, a protein involved in the regulation of chromatin, which is the complex of proteins and nucleic acids contained in the nucleus of cells. However, research still has a long way to go to identify therapeutic approaches. An Italian team, coordinated by the University of Trento, has taken a step forward in this direction (2020-11-09)

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