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Current Cystic fibrosis News and Events

Current Cystic fibrosis News and Events, Cystic fibrosis News Articles.
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Cystic fibrosis carriers at increased risk of digestive symptoms
Researchers have found that carriers of the most common genetic variant that causes cystic fibrosis experience some symptoms similar to those of people with cystic fibrosis. (2019-10-17)
Study reveals how mucus tames microbes
A study from MIT reveals glycans, branched sugar molecules found in mucus, can prevent bacteria from communicating with each other and forming infectious biofilms, effectively rendering the microbes harmless. (2019-10-14)
CF patients experience improved lung health with lumacaftor-ivacaftor but with caveats
In adolescent and adult patients with cystic fibrosis taking lumacaftor-ivacaftor (ORKAMBIĀ®), the combination drug appears to improve lung function and body weight and reduce the need for intravenous antibiotic treatment, according to a French study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. (2019-10-11)
Drug reverses signs of liver disease in people living with HIV
Researchers at the National Institutes of Health and their colleagues at Massachusetts General Hospital (MGH) in Boston report that the injectable hormone tesamorelin reduces liver fat and prevents liver fibrosis (scarring) in people living with HIV. (2019-10-11)
Researchers identify potential therapy for liver disease in people living with HIV
Researchers have identified a novel therapeutic strategy to significantly improve liver disease in people living with HIV. (2019-10-11)
Researchers identify new therapeutic target for pulmonary fibrosis
Researchers in Japan have identified a genetic mutation that causes a severe lung disease called idiopathic pulmonary fibrosis (IPF) by killing the cells lining the lung's airways. (2019-10-10)
'Wild idea' opens possible new frontier for preventing ovarian cancer
A laboratory study published in Clinical Cancer Research offers a new hypothesis about how ovarian cancer forms and suggests how it might be prevented. (2019-10-09)
Severe allergic reactions identified with peripherally inserted central catheters
Peripherally inserted central catheters (PICCs) that use a magnetized tip to guide insertion were associated with serious allergic reactions in patients, according to a study published today in Infection Control & Hospital Epidemiology, the journal for the Society for Healthcare Epidemiology of America. (2019-10-08)
Common denominator that triggers asthma in favorable environments
Some so-called pro-allergic environments strongly promote the development of asthma and are responsible for the dramatic increase in the prevalence of asthma, especially in industrialized countries. (2019-10-07)
Temple scientists ID new targets to treat fibrosis -- a feature of many chronic diseases
When it comes to repairing injured tissue, specialized cells in the body known as fibroblasts are called into action. (2019-10-04)
Preaching the benefits of vaccination in an increasingly skeptical world
The jam-packed schedule for IDWeek2019 includes presentations about vaccines and other therapies that are effective against infectious diseases, new research insights about emerging infections and updates about global outbreaks past and present, such as measles and Zika. (2019-10-02)
Nanoparticles wiggling through mucus may predict severe COPD
In a proof-of-concept experiment, researchers from Johns Hopkins Medicine say they have successfully used microscopic man-made particles to predict the severity of patients' chronic obstructive pulmonary disease (COPD) by measuring how quickly the particles move through mucus samples. (2019-09-30)
The Lancet journals: Papers at ERS Congress 2019
The following papers will be presented at the ERS Congress 2019, organised by the European Respiratory Society, in Madrid and published simultaneously in either The Lancet or The Lancet Respiratory Medicine journals. (2019-09-30)
'Smart shirt' can accurately measure breathing and could be used to monitor lung disease
A smart shirt that measures lung function by sensing movements in the chest and abdomen has proved to be accurate when compared to traditional testing equipment, according to research presented at the European Respiratory Society International Congress. (2019-09-29)
Nintedanib slows progression for broad range of scarring lung diseases
Nintedanib, a medication approved for the treatment of idiopathic pulmonary fibrosis, slows the decline in lung function among patients with a broad range of scarring lung diseases. (2019-09-29)
Promising steps towards a treatment for pulmonary fibrosis
Research published in the journal Science Translational Medicine on 25 September by members of the Cardiovascular Disease Mechanisms group at the MRC LMS in collaboration with Duke-NUS Medical School, National Heart Centre Singapore & National Heart and Lung Institute, Imperial College London, showed that blocking a protein called interleukin-11 (IL-11) using therapeutic antibodies can reverse the fibrosis in the lung. (2019-09-25)
New insights into the healing capacity of the heart
Researchers report that the Hippo pathway is important for maintaining adult murine cardiac fibroblasts in their resting state. (2019-09-25)
CU researchers identify potential target for cardiac fibrosis treatment
A research team led by scientists at the University of Colorado School of Medicine has identified a potential target for treating heart failure related to fibrosis. (2019-09-17)
New cardiac fibrosis study identifies key proteins that translate into heart disease
The formation of excess fibrous tissue in the heart, which underlies several heart diseases, could be prevented by inhibiting specific proteins that bind to RNA while its code is being translated. (2019-09-12)
CAR T-cell therapy may be harnessed to treat heart disease
CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease. (2019-09-11)
Bioengineers explore cardiac tissue remodeling after aortic valve replacement procedures
Researchers have developed biomaterial-based 'mimics' of heart tissues to measure patients' responses to an aortic valve replacement procedure, offering new insight into the ways that cardiac tissue re-shapes itself post-surgery. (2019-09-11)
Talking receptors may affect relaxin at work
A research team investigating the promising anti-fibrotic effects of a drug version of the hormone, relaxin, has discovered that the receptor through which it mediates its therapeutic actions can communicate and/or interact with other receptors in cells that contribute to fibrosis progression. (2019-09-11)
Genetic mutation linked to flu-related heart complications
For the first time, research in mice has shown a link between a genetic mutation, flu and heart irregularities that researchers say might one day improve the care of flu patients. (2019-09-10)
Acute periodontal disease bacteria love colon and dirt microbes
Mythbuster: The idea that bacterial collaborations within microbiomes, like in the mouth, have evolved to be generous and exclusive very much appears to be wrong. (2019-09-09)
Possible treatment breakthrough for the rare disease arrhythmogenic right ventricular cardiomyopathy
Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Puerta de Hierro hospital in Majadahonda have found a possible treatment for this disease. (2019-09-05)
In cystic fibrosis, lungs feed deadly bacteria
A steady supply of its favorite food helps a deadly bacterium thrive in the lungs of people with cystic fibrosis, according to a new study by Columbia researchers. (2019-08-21)
Scientists find powerful potential weapon to overcome antibiotic resistance
Staphylococcus aureus bacteria are a major cause of serious infections that often persist despite antibiotic treatment, but scientists at the UNC School of Medicine have now discovered a way to make these bacteria much more susceptible to some common antibiotics. (2019-08-14)
Research on cholera adds to understanding of the social life of bacteria
Strains of the bacterium Vibrio cholerae transform themselves from small, comma-shaped cells to long filaments in nutrient-poor environments to aid short-term survival. (2019-08-09)
A new pathway: researchers identify potential treatment target for Crohn's disease
Crohn's disease is a form of inflammatory bowel disease (IBD) in which the body's own immune system attacks the gastrointestinal tract, and treatment is focused on controlling the symptoms of the disease in its acute phase and managing it in remission. (2019-08-08)
New intra-nasal imaging to study airways in patients with cystic fibrosis
Researchers describe minimally invasive new tool for viewing differences in the nasal airways of cystic fibrosis patients in vivo at a cellular level. (2019-08-07)
Cibio knocks out cystic fibrosis
The fight against cystic fibrosis continues, targeting in particular some of the mutations that cause it. (2019-08-07)
3D miniature livers lead the way to patient-specific drug discovery
Researchers from TMDU and CCHMC developed a reproducible method for creating multicellular miniature liver organoids from pluripotent stem cells. (2019-08-02)
Scientists develop promising drug for treating ovarian, pancreatic cancers
Cancer scientists at Houston Methodist have been looking for more effective late-stage treatments for ovarian and pancreatic cancers and may have found one. (2019-07-22)
Ivacaftor may reduce common infections in patients with CF
Patients with cystic fibrosis who take ivacaftor appear to have fewer respiratory infections over time than those not taking the drug, according to new research published online in the Annals of the American Thoracic Society. (2019-07-19)
Waking up sleeping bacteria to fight infections
Researchers in the group of Jan Michiels (VIB-KU Leuven Center for Microbiology) identified a mechanism of how sleepy bacteria wake up. (2019-07-18)
TGen-led study finds link between gene and severe liver damage
Researchers have found that a gene known as AEBP1 may play a central role in the development, severity and potential treatment of liver disease, according to a study by Temple University, the Geisinger Obesity Institute and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope. (2019-07-18)
Rare inherited enzyme disorder yields insight into fibrosis
St. Jude investigators have discovered an association between a deficiency in the enzyme neuraminidase 1 and the build-up of connective tissue in organs, suck as the muscle, kidney, liver, heart and lungs. (2019-07-17)
Shaky scaffold changes lung infrastructure
Researchers identify changes in enzymes that may contribute to lung damage in rare genetic disorder. (2019-07-17)
Human pancreas on a chip opens new possibilities for studying disease
Scientists created human pancreas on a chip that allowed them to identify the possible cause of a frequent and deadly complication of cystic fibrosis (CF) called CF-Related Diabetes, or CFRD. (2019-07-16)
Hinge-like protein may open new doors in cystic fibrosis treatment
Drugs known as potentiators alleviate some symptoms of cystic fibrosis. (2019-07-09)
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