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How do basal ganglia neurons convey information for the control of voluntary movements?
Researchers revealed how neurons in the basal ganglia, which are a brain region crucial for the control of voluntary movements and whose damage induces motor impairment, such as Parkinson's disease, convey information for the movement control by recording activity of multiple neurons simultaneously in Japanese monkeys. (2020-10-27)
Death rates among people with severe COVID-19 drop by a half in England
Death rates from people with severe COVID-19 in hospital have dropped to around a half of the rate at the peak of the pandemic, new research has revealed. (2020-10-27)
Black Hispanic individuals hardest hit by COVID-19
Results from a new study led by Boston Medical Center (BMC) demonstrate the disproportionate impact of COVID-19 on Hispanic groups within the US, with the most severe outcomes, including death and intensive care, among Hispanic Black individuals. (2020-10-27)
Fatal police shootings among black Americans remain high, unchanged since 2015
Overall, the report found 5,367 fatal police shootings in the five-year span, of which 4,653 were eligible for analysis because both race and age were identified. (2020-10-27)
Study helps explain declines in death rates from COVID-19
Fewer New Yorkers are dying from the coronavirus than health experts had anticipated, a new study shows. (2020-10-22)
Critically ill infants given blood transfusions before surgery have poorer outcomes
Critically ill newborns who receive blood transfusions prior to surgery had about a 50% increased rate of complications or death than those who did not receive transfusions, according to a new study published today in Pediatrics by Nemours Children's Health System researchers. (2020-10-21)
Mammography screening saves lives also in older age
Mammography, which is an x-ray picture of the breast, is efficient also for women over the age of 70. (2020-10-20)
Mortality rate higher for US rural residents
A recent study by Syracuse University sociology professor Shannon Monnat shows that mortality rates are higher for U.S. working-age residents who live in rural areas instead of metro areas, and the gap is getting wider. (2020-10-20)
New tool predicts risks of hospital admission and death from Covid-19
A new risk tool, developed by UK researchers to predict a person's risk of being admitted to hospital and dying from Covid-19 has been published by The BMJ today. (2020-10-20)
Young people hospitalized with COVID-19 face substantial adverse outcomes
Researchers from Brigham and Women's Hospital analyzed records from 419 hospitals using the Premier Healthcare Database to study the clinical trajectories of 3,222 hospitalized COVID-19 patients aged 18-34. (2020-10-08)
Study shows similar antibody response to key SARS-CoV-2 'spike' protein in COVID-19
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) shows that antibody responses to related to the key 'spike' protein of the SARS-CoV-2 virus are similar in COVID-19 patients with and without diabetes, boosting hopes that vaccines involving this same protein will have a high chance of being as effective in vulnerable patients with diabetes as they will be in the general population. (2020-10-08)
Urban air pollution may make COVID-19 more severe for some
As the pandemic persists, COVID-19 has claimed more than 200,000 lives in the United States and damaged the public health system and economy. (2020-10-07)
Preliminary results of two large immune therapy studies show promise in advanced cervical cancer
COLUMBUS, Ohio - Preliminary results from two independent, phase II clinical trials investigating a new PD-1 (programmed cell death protein 1)-based immune therapy for metastatic cervical cancer suggest potential new treatment options for a disease that currently has limited effective options and disproportionately impacts younger women. (2020-10-05)
Study: Sleep apnea treatment reduces heart problems in patients with prediabetes
A new study found that people with prediabetes and obstructive sleep apnea can reduce their daytime resting heart rate and risk of cardiovascular disease by using a CPAP machine at night. (2020-10-01)
People with Parkinson's disease have a higher risk of dying from COVID-19
A new database analysis of approximately 80,000 patients shows that people with Parkinson's disease (PD) have a 30% higher death rate from COVID-19 than people without the neurodegenerative condition. (2020-10-01)
Irregular and long menstrual cycles linked to greater risk of early death
Irregular and long menstrual cycles in adolescence and adulthood are associated with a greater risk of early death (before age 70), finds a study published by The BMJ today. (2020-09-30)
Patients' breathing test comes up short on accuracy, study finds
A routine test used to monitor patients' breathing may be unreliable and putting them at risk, a study suggests. (2020-09-27)
Adequate levels of vitamin D reduces complications, death among COVID-19 patients
Hospitalized COVID-19 patients who were vitamin D sufficient, with a blood level of 25-hydroxyvitamin D of at least 30 ng/mL (a measure of vitamin D status), had a significant decreased risk for adverse clinical outcomes including becoming unconscious, hypoxia (body starved for oxygen) and death. (2020-09-25)
Shorter time from symptom onset to hospitalization is associated with worse outcome in patients with COVID-19
New research presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, held online) shows that a shorter time from symptom onset to hospitalisation is associated with more serious disease and death in patients with COVID-19. (2020-09-25)
Opening an autophagy window as the apoptosis door starts to close
Tokyo Medical and Dental University (TMDU) researchers have successfully attached the cancer cell-targeting antibody Trastuzumab to a previously reported supermolecule that induces autophagic cell death. (2020-09-24)
Carriers of two genetic mutations at greater risk for illness and death from COVID-19
Tel Aviv University researchers suggest that carriers of the genetic mutations PiZ and PiS are at high risk for severe illness and even death from COVID-19. (2020-09-24)
Age restrictions for handguns make little difference in homicides
In the United States, individual state laws barring 18- to 20-year-olds from buying or possessing a handgun make little difference in the rate of homicides involving a gun by people in that age group, a new University of Washington study has found. (2020-09-24)
Study: Death counts fail to capture full mortality effects of COVID-19
A study published in the Journal of Public Health finds that for each person in the U.S. who died after contracting COVID-19, an average of nearly 10 years of life had been lost. (2020-09-23)
Risk of death may increase for successive generations of immigrants with type 2 diabetes
A 10-year nationwide study investigating survival rates in all people with type 2 diabetes in Sweden, to be published in Diabetologia, finds that non-Western immigrants experienced a higher risk of death with each generation born in the country. (2020-09-22)
Higher risk of death in cancer patients with COVID-19 may be due to advanced age and more pre-existing conditions, rather than cancer itself
New research presented at this this week's ESCMID Conference on Coronavirus Diseases (ECCVID, online 23-25 September) suggests that the poor outcomes and higher death rates in cancer patients with COVID-19 could be due to them generally being older and having more underlying conditions, rather than due to the cancer itself. (2020-09-22)
COVID-19 and the decolonization of Indigenous public health
Indigenous self-determination, leadership and knowledge have helped protect Indigenous communities in Canada during the coronavirus disease 2019 (COVID-19) pandemic, and these principles should be incorporated into public health in future, argue the authors of a commentary in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/lookup/doi/10.1503/cmaj.200852. (2020-09-21)
Recurrent heart attacks on the decline, yet risk remains high
After surviving a heart attack, the proportion of patients experiencing a repeat attack within a year fell between 2008 and 2017, with the greatest decline in women. (2020-09-21)
Potent drug supply drop, not domestic drug policies, likely behind 2018 OD death downturn
The slight decline in drug overdose deaths in 2018 coincides with Chinese regulations on the powerful opioid carfentanil, rather than the result of domestic U.S. efforts to curb the epidemic, a new analysis reveals. (2020-09-16)
Online tool informs recovery prospects for sepsis survivors
A doctor at Guy's and St Thomas', working with colleagues at the Intensive Care National Audit & Research Centre (ICNARC), has developed a tool to predict the risk of readmission to hospital or death in the first year after leaving hospital for adult survivors of sepsis. (2020-09-15)
Immunotherapy: Enhancing the therapeutic effectiveness of photothermal cancer treatments
Immune checkpoint blockade is the most promising therapy mode of cancer immunotherapy. (2020-09-15)
Depression risk detected by measuring heart rate changes
For the first time doctors have shown that measuring changes in 24-hour heart rate can reliably indicate whether or not someone is depressed. (2020-09-11)
COPD program decreases 30-day hospital readmission, may increase mortality
The 30-day readmission rate for patients with chronic obstructive pulmonary disease has decreased but the mortality rate has increased. (2020-09-10)
'Social smokers' face disproportionate risk of death from lung disease and lung cancer
'Social smokers' are more than twice as likely to die of lung disease and more than eight times as likely to die of lung cancer than non-smokers, according to research presented at the European Respiratory Society International Congress. (2020-09-03)
Study finds hospital-diagnosed overweight or obesity linked with markedly higher risk of death over 40 years
Individuals whose overweight or obesity is diagnosed in hospital are 60% more likely to die compared to the general population, according to a nationwide Danish study that followed over 1.9 million people for up to 40 years, being presented at The European and International Congress on Obesity (ECOICO), held online this year from 1-4 September. (2020-09-02)
Men with larger waists more likely to die of prostate cancer
A study of more than 200,000 UK men, being presented at this year's European and International Conference on Obesity (ECOICO), held online this year from September 1-4, reveals that there is a link between central adiposity (concentration of body fat around the belly and waist) and the risk of death from prostate cancer. (2020-09-01)
Early rhythm control therapy improves outcomes in patients with atrial fibrillation
Patients with newly diagnosed atrial fibrillation benefit from early rhythm control therapy, according to results of the EAST-AFNET 4 trial presented in a Hot Line session today at ESC Congress 2020. (2020-08-31)
DAPA-CKD trial meets primary endpoint in patients with chronic kidney disease
Dapagliflozin reduces the risk of kidney failure, death from cardiovascular causes or heart failure hospitalisation and all-cause mortality in chronic kidney disease patients with or without type 2 diabetes. (2020-08-31)
Obesity -- the deadly disease that nobody dies of
New research presented at the European and International Conference on Obesity (ECO ICO 2020), held online this year (Sept. (2020-08-31)
Premature deaths from alcoholic liver disease rising as gap between men and women narrows
A new study in the American Journal of Preventive Medicine identifies emerging patterns in the rate of and age at premature death from alcoholic (alcohol-associated) liver disease (ALD) in the US over the last two decades. (2020-08-27)
Children and young people have less severe COVID-19 than adults and death is exceptionally rare
Children and young people have less severe covid-19 than adults and death is exceptionally rare, only occurring in children with serious underlying conditions, confirms a study published by The BMJ today. (2020-08-27)
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