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Current Disease progression News and Events

Current Disease progression News and Events, Disease progression News Articles.
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Drug combination may become new standard treatment for advanced kidney cancer
A combination of two drugs -- one of them an immunotherapy agent -- could become a new standard, first-line treatment for patients with metastatic kidney cancer, says an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial. (2019-02-16)
A new mouse model may unlock the secrets of type I diabetes
Finding new treatments or a cure for type I diabetes has been elusive in part because scientists have not had a reliable animal model that mimics the full scope of human type I diabetes. (2019-02-12)
The search for the holy grail: Promising strategies for slowing, stopping, or reversing Parkinson's disease
Understanding of the processes involved in Parkinson's disease (PD) degeneration has vastly improved over the last 20 years. (2019-02-12)
Breaking the vicious cycles of age-related diseases
Aleksey Belikov from MIPT has proposed that rapid progression of age-related diseases may result from the formation of so-called vicious cycles. (2019-02-11)
Researchers develop human cell-based model to study small cell lung cancer
Researchers from Weill Cornell Medicine have used human embryonic stem cells to create a new model system that allows them to study the initiation and progression of small cell lung cancer (SCLC). (2019-02-08)
Malignant bone marrow disease: New hope for MPN patients
Myeloproliferative neoplasms (MPNs) are still difficult to treat. A team from Vetmeduni Vienna and the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences/Medical University of Vienna has discovered a new therapeutic approach that could fundamentally change this situation, as evidenced by a study that was published recently in the academic journal Blood. (2019-02-05)
NUS study: Nanoparticles may promote cancer metastasis
Researchers from the National University of Singapore have found that cancer nanomedicine, which are designed to kill cancer cells, may accelerate metastasis. (2019-01-31)
What you eat could impact your brain and memory
High levels of a satiety hormone could decrease a person's likelihood of developing Alzheimer's disease. (2019-01-28)
Myocarditis: Overshooting the mark
Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have shown that a protein called midkine, a member of the class of signaling molecules known as cytokines, is a key driver of inflammation in the heart muscle that can lead to heart failure in patients with myocarditis. (2019-01-28)
New therapeutic targets for kidney fibrosis emerge
A new study, published in Science Translational Medicine, identifies key factors involved in this cell cycle arrest and illuminating their consequences. (2019-01-28)
MD Anderson study shows FGL2 protein may be an effective target for glioblastoma
Glioblastoma (GBM) does not attract robust T cell immune responses. (2019-01-25)
Old cells repair damage in the brains of MS patients
A new study shows that there is a very limited regeneration of cells in the brain of patients diagnosed with multiple sclerosis (MS). (2019-01-23)
Should we rename low-risk cancers?
Should we rename low-risk ('indolent') cancers in a bid to reduce anxiety and harm from unnecessary investigation and treatment? (2019-01-23)
Faulty molecular master switch may contribute to AMD
A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration (AMD). (2019-01-22)
New skin test detects prion infection before symptoms appear
Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. (2019-01-22)
Early prediction of Alzheimer's progression in blood
Scientists at the German Center for Neurodegenerative Diseases, the Hertie Institute for Clinical Brain Research and the University Hospital Tuebingen show that a protein found in the blood can be used to precisely monitor disease progression of Alzheimer's long before first clinical signs appear. (2019-01-21)
New therapeutic avenue in the fight against chronic liver disease
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has introduced a novel targeted drug delivery system in the fight against cancer. (2019-01-18)
Multiple sclerosis treatments delay progression of the disease
An international study finds multiple sclerosis treatments have long-term benefits, and that early treatment is important. (2019-01-16)
Unraveling the genetic causes of skin cancer
American University Associate Professor of Biology Katie DeCicco-Skinner and her colleagues are helping to identify the genetic factors that lead to squamous cell carcinoma. (2019-01-13)
Calcium specks may help detect heart disease in South Asians
Specks of calcium in the heart's artery walls could be an important prognostic marker of early cardiovascular disease in South Asians and may help guide treatment in this population, according to a study by researchers at UC San Francisco. (2019-01-11)
Expression of a molecule in blood cells predicts atherosclerosis risk
CNIC's scientists have found that the expression level of the molecule CD69 in blood cells inversely predicts the appearance of subclinical atherosclerosis (developing before symptoms appear) independently of classical cardiovascular risk factors. (2019-01-10)
UCLA study overturns dogma of cancer metabolism theory
Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism. (2019-01-09)
Defective immune cells in the brain cause Alzheimer's disease
Mutations of the TREM2 gene can significantly increase the risk of Alzheimer's disease. (2019-01-08)
Researchers uncover new mechanism of gene regulation involved in tumor progression
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona, Spain, have discovered a new mechanism controlling the expression of a set of genes important for cell proliferation and tumor progression. (2019-01-08)
Mayo Clinic discovers biological markers that could guide treatment for prostate cancer
Genetic alterations in low-risk prostate cancer diagnosed by needle biopsy can identify men that harbor higher-risk cancer in their prostate glands, Mayo Clinic has discovered. (2019-01-03)
Parkinson's disease protein buys time for cell repair
Loss of the protein Parkin causes certain forms of Parkinson's disease, a neurodegenerative condition involving death of neurons. (2018-12-20)
Parkinson's disease experts devise a roadmap
A recently discovered protein, alpha-synuclein, has become one of the most attractive targets for developing new drugs with the potential to slow down or arrest the progression of Parkinson's disease. (2018-12-20)
New research shows how a fatty diet can lead to life-threatening liver disease
A new study by USC scientists provides new insight on how dietary fat and cholesterol drive the development of non-alcoholic steatohepatitis (NASH), a serious form of non-alcoholic fatty liver disease (2018-12-20)
Kidney failure on the rise in Australians under 50 with type 2 diabetes
A study of more than 1.3 million Australians with diabetes has found that kidney failure is increasing in people with type 2 diabetes aged under 50 years, leading to reduced quality of life and placing growing demand on the country's kidney dialysis and transplantation services. (2018-12-19)
Experts identify 'tipping point' in tree disease outbreaks
Experts have found a way to model disease progression and predict the 'tipping point' of a disease, providing early warning indicators that an epidemic is imminent and action needs to be taken. (2018-12-18)
Biologists identify promising drug for ALS treatment
A new drug could significantly slow the progression of ALS, also known as Lou Gehrig's disease, according to new research by University of Alberta biologists. (2018-12-18)
Alzheimer peripheral blood: mRNA expression of amyloid precursor protein cleaving enzyme
Alzheimer's disease (AD) is the most common cause of dementia in elderly populations. (2018-12-14)
Researchers discover unique immune cell likely drives chronic inflammation
For the first time, researchers have identified that an immune cell subset called gamma delta T cells that may be causing and/or perpetuating the systemic inflammation found in normal aging in the general geriatric population and in HIV-infected people who are responding well to drugs (anti-retrovirals). (2018-12-11)
Two compounds in coffee may team up to fight Parkinson's
Rutgers scientists have found a compound in coffee that may team up with caffeine to fight Parkinson's disease and Lewy body dementia -- two progressive and currently incurable diseases associated with brain degeneration. (2018-12-10)
Faulty sensing: Cellular energy sensor linked to the progression of chronic kidney disease
Chronic kidney disease (CKD) is associated with energy depletion in kidney cells, resulting in reduced kidney function. (2018-12-07)
New generation of therapeutics based on understanding of aging biology show promise for Alzheimer's disease
A scientific strategy that explores therapeutic targets based on the biology of aging is gaining ground as an effective approach to prevent and treat Alzheimer's disease, according to research published in the December 7, 2018 online issue of Neurology®. (2018-12-07)
Liquid biopsies in SOLAR-1 trial predict benefit of Alpelisib in PIK3CA-mutant breast cancer
Liquid biopsy-based assessment of PIK3CA mutational status served as a better indicator of progression-free survival compared with analysis of tissue biopsy in breast cancer patients enrolled in the phase III clinical trial SOLAR-1, according to data presented at the 2018 San Antonio Breast Cancer Symposium. (2018-12-06)
Ibrutinib plus rituximab superior to standard treatment for patients with chronic leukemia
The results of the E1912 phase 3 clinical trial show that the novel treatment of ibrutinib and rituximab is superior to the historical best treatment, which is chemotherapy. (2018-12-04)
Protein may slow progression of emphysema, Rutgers study finds
A protein generated as part of our body's immune response to intestinal worms could slow the progression of emphysema, according to a Rutgers study. (2018-12-04)
Genetic relic of the 'black death' may offer clues in treating liver disease
A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati (UC) College of Medicine physician-scientist. (2018-12-03)
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