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Current Disease progression News and Events

Current Disease progression News and Events, Disease progression News Articles.
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Potential target for diabetes-associated Alzheimer's disease
Researchers have identified a protein that may contribute to the progression of Alzheimer's disease pathology in type-2 diabetes, reports a new study of male mice and human brain tissue. (2019-09-16)
Exercising at home has a positive effect on Parkinson's patients
In a large double-blind study, Radboud university medical center researchers show that patients in the early stages of Parkinson's disease can exercise regularly at home for 6 months. (2019-09-12)
Markey researchers discover role of nuclear glycogen in non-small cell lung cancers
Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers. (2019-09-12)
Cancer research -- The genetic context is crucial
An Ludwig-Maximilians-Universitaet (LMU) in Munich team has uncovered a mechanism behind the variability in the clinical course of Ewing sarcoma. (2019-09-11)
KEYNOTE-024 three-year survival update
First line pembrolizumab monotherapy provides durable long-term overall survival benefit compared to chemotherapy, according to data presented today by Dr. (2019-09-10)
Patients taking nivolumab experience five-fold increase in overall survival compared to chemotherapy
Pooled data on two clinical trials demonstrate patients taking nivolumab realized a greater than five-fold increase in five-year overall survival rate compared with the chemotherapy docetaxel. (2019-09-10)
Nivolumab combined with ipilimumab safe as first-line therapy for lung cancer patients
Combining the PD-1 immune check point inhibitor nivolumab with the monoclonal antibody ipilimumab showed a consistent safety profile in special populations with advanced non-small cell lung cancer (NSCLC), according to research presented today by at the IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer. (2019-09-08)
Apathy as an indicator of progression in Huntington's disease
IDIBELL-UB researchers associate changes in white matter connectivity in different subtypes of apathy, one of the most common psychiatric syndromes in Huntington's disease (HD). (2019-09-05)
New study confirms protective effect of diabetes drugs against kidney failure
A new meta-analysis published in Lancet Diabetes and Endocrinology has found that SGLT2 inhibitors can reduce the risk of dialysis, transplantation, or death due to kidney disease in people with type 2 diabetes. (2019-09-05)
Study maps genetics of early progression in TB
Study identifies possible gene variants that determine whether a person infected with TB will progress rapidly to active disease. (2019-09-04)
Temple scientists identify promising new target to combat Alzheimer's disease
In the case of Alzheimer's disease, Temple researchers show that mitochondrial calcium transport remodeling -- what appears to be an attempt by cells to compensate for flagging energy production and metabolic dysfunction -- while initially beneficial, ultimately becomes maladaptive, fueling declines in mitochondrial function, memory, and learning. (2019-09-03)
Creation of new brain cells plays an underappreciated role in Alzheimer's disease
In a new study published in the Journal of Neuroscience, Sangram Sisodia and his colleagues show how in genetic forms of Alzheimer's, a process called neurogenesis, or the creation of new brain cells, can be disrupted by the brain's own immune cells. (2019-08-30)
Lab-on-a-chip may help identify new treatments for liver disease
Investigators have developed a 'lab on a chip' technology that can simulate different levels of non-alcoholic fatty liver disease progression. (2019-08-29)
A protective factor against Alzheimer's disease?
Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the Institute for Stroke and Dementia Research (ISD) at the University Hospital of the Ludwig-Maximilians-Universität (LMU) in Munich have found that a protein called TREM2 could positively influence the course of Alzheimer's disease. (2019-08-29)
Strike three
Researchers uncover a previously unrecognized mechanism that may accelerate polycystic kidney disease. (2019-08-26)
Scientists closer to solving mystery of why lean people get fatty liver disease
Researchers from The Westmead Institute for Medical Research (WIMR) have discovered how fatty liver disease develops in lean people, aiding the development of potential treatments for these patients. (2019-08-26)
Novel method identifies the right individual exosomes
There is a growing demand for diagnostic markers for early disease detection and prognosis. (2019-08-26)
Exercise associated with benefit to patients with advanced colorectal cancer
Patients with metastatic colorectal cancer who engaged in moderate exercise while undergoing chemotherapy tended to have delayed progression of their disease and fewer severe side effects from treatment, according to the results of a new study. (2019-08-14)
Air pollution can accelerate lung disease as much as a pack a day of cigarettes
Air pollution -- especially ozone air pollution which is increasing with climate change -- accelerates the progression of emphysema of the lung, according to a new study led by the University of Washington, Columbia University and the University at Buffalo. (2019-08-13)
Comparison between major types of arthritis based on diagnostic ultrasonography
Ultrasound is a non-invasive and relatively inexpensive means of diagnosing a number of medical conditions. (2019-08-09)
Experimental treatment slows prion disease, extends life of mice
Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents' lives, according to a new report in JCI Insight. (2019-08-01)
Stress in cervical cancer patients associated with higher risk of cancer-specific mortality
Psychological stress was associated with a higher risk of cancer-specific mortality in women diagnosed with cervical cancer. (2019-08-01)
Aspirin improves liver function after embolization of hepatocellular carcinoma
Aspirin therapy is associated with both improved liver function test results and survival after transarterial embolization for hepatocellular carcinoma, according to an ahead-of-print article by F. (2019-07-31)
New gene found for a deadly childhood cancer offers possibility of targeted drug therapy
Neuroblastoma accounts for 15% of total childhood cancer deaths and survival rates of high-risk neuroblastoma patients is 50%. (2019-07-26)
Molecule reduces accumulation of toxic protein in Parkinson's disease model
The discovery supports GM1 ganglioside as a potential target for Parkinson's therapy. (2019-07-24)
Staging β-amyloid pathology with amyloid positron emission tomography
This multicenter study used in vivo β-amyloid cerebrospinal fluid, a biomarker of Alzheimer disease, and positron emission tomography findings to track progression of Alzheimer disease over six years among study participants. (2019-07-17)
Exercise offers protection against Alzheimer's
Higher levels of daily physical activity may protect against the cognitive decline and neurodegeneration (brain tissue loss) from Alzheimer's disease. (2019-07-16)
Discovered a new therapeutic target for the treatment of Alzheimer's disease
A study led by researchers of the Spanish National Research Council (CSIC) and published in the journal Nature Neuroscience has identified a new therapeutic target for the treatment of Alzheimer's disease. (2019-07-15)
Researchers describe new ALS biomarkers, potential new drug targets
Researchers at the University of Illinois at Chicago have described unique populations of neurons and associated cells in the spinal cords of patients who died of ALS. (2019-07-15)
Puzzling brain disease could now be better diagnosed, treated
Scientists have developed an animal model that may provide a path toward improving the diagnosis and treatment of the devastating brain disease chronicled in the bestselling autobiography 'Brain on Fire.' The book, along with a 2017 movie by the same name, traces newspaper reporter Susannah Cahalan's harrowing descent into the throes of the disease. (2019-07-10)
Cancer genes and the tumor milieu
In a recent study published in Cancer Research, researchers demonstrate the role of an oncogene in altering the immediate environment of tumors. (2019-07-08)
Protein-linked sugars are crucial for the uptake of proteins linked to Parkinson's disease
New research from the University of Pennsylvania shows how glycoproteins, proteins with added sugar molecules, influence the uptake of protein aggregates that are associated with Parkinson's disease. (2019-07-03)
New imaging molecule captures brain changes tied to progressive multiple sclerosis
'There's more to multiple sclerosis than white matter lesions,' said corresponding author Tarun Singhal, M.D., a neurologist at the Ann Romney Center for Neurologic Diseases at the Brigham. (2019-07-01)
No cell is an island
In a new study, published on June 25, 2019, in the journal eLife, the researchers report that higher levels of doublets -- long dismissed as technical artifacts -- can be found in people with severe cases of tuberculosis or dengue fever. (2019-06-25)
Earlier diagnosis and treatment assessment of tuberculosis achieved with pet/ct
Research presented at the Society of Nuclear Medicine and Molecular Imaging's 2019 Annual Meeting shows that molecular imaging with 18F-FDG positron emission tomography/computed tomography (PET/CT) can evaluate tuberculosis at the molecular level, effectively identifying diseased areas and guiding treatment for patients. (2019-06-24)
Inflammatory mechanisms may underlie increased risk of prostate cancer among WTC responders
Inflammatory and immune-regulatory mechanisms were found to be altered in animal models and in archived prostate cancer tumor samples of responders exposed to dust from the World Trade Center terrorist attacks on Sept. (2019-06-20)
Scientists map toxic proteins linked to Alzheimer's
A team of researchers from McMaster University has mapped at atomic resolution a toxic protein linked to Alzheimer's disease, allowing them to better understand what is happening deep within the brain during the earliest stages of the disease. (2019-06-20)
Sugars that coat proteins are a possible drug target for pancreatitis
CA19-9 is a complex sugar structure that coats proteins. Elevated levels of CA19-9 was found to cause inflammation in the pancreas in mice and promote rapid progression to pancreatic cancer. (2019-06-20)
Good physical fitness in middle age linked to lower chronic lung disease risk
Good heart and lung (cardiorespiratory) fitness in middle age is associated with a lower long term risk of chronic lung disease (COPD), suggests Danish research published online in the journal Thorax. (2019-06-18)
Indigestion remedy slows kidney function decline and improves survival in late-stage CKD
As chronic kidney disease (CKD) progresses, the kidneys become less able to maintain a healthy balance of acids in the body. (2019-06-14)
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