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Current Drug combination News and Events

Current Drug combination News and Events, Drug combination News Articles.
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Addition of sintilimab to pemetrexed and platinum improved progression-free survival
The interim analysis of ORIENT-11, a phase III double-blind randomized trial has shown a nearly two-fold increase in progression-free survival with addition of sintilimab to chemotherapy in patients with advanced or metastatic non-squamous non-small cell lung cancer without EGFR or ALK genomic aberrations, according to research data presented today at the International Association for the Study of Lung Cancer Virtual Presidential Symposium. (2020-08-08)
Smartwatch tracks medication levels to personalize treatments
Engineers at the UCLA Samueli School of Engineering and their colleagues at Stanford School of Medicine have demonstrated that drug levels inside the body can be tracked in real time using a custom smartwatch that analyzes the chemicals found in sweat. (2020-08-07)
SFU chemist's new process fast-tracks drug treatments for viral infections and cancer
Discovering antiviral and anticancer drugs will soon be faster and cheaper thanks to new research from Simon Fraser University chemist Robert Britton and his international team. (2020-08-07)
Radboudumc research leads to simplified dosage of HIV medicine for children
Children living with HIV can benefit from an adapted, simpler combination therapy. (2020-08-04)
Darolutamide in prostate cancer: Indication of considerable added benefit
The advantages in the outcome categories of mortality, morbidity and health-related quality of life are not accompanied by disadvantages. (2020-08-03)
Cannabinoids may affect activity of other pharmaceuticals
Cannabinoid-containing products may alter the effects of some prescription drugs, according to Penn State College of Medicine researchers. (2020-08-03)
Investigational breast cancer vaccine plus immune therapy work well in tandem
A vaccine for HER2-positive breast cancers that is being tested in a clinical trial at Duke Cancer Institute is part of an effective, two-drug strategy for enlisting the immune system to fight tumors, according to a Duke-led study in Clinical Cancer Research, a journal of the American Association for Cancer Research. (2020-07-30)
Adverse effects from cancer drug trials explained
Certain type of cancer drugs that promote the death of cells can actually be harmful if combined with other treatments that damage our DNA, RNA or proteins, researchers have found. (2020-07-29)
Some "inactive" drug ingredients may not be inert
The inactive ingredients that make up a major component of drug formulations may not be as inactive as previously thought, researchers report. (2020-07-23)
Researchers ID new target in drive to improve immunotherapy for cancer
UCLA researchers have identified a potential new combination therapy to treat advanced head and neck squamous cell carcinoma, the most common type of head and neck cancer. (2020-07-21)
Immunotherapy safe for patients with COVID-19, cancer
Preliminary data from researchers at the University of Cincinnati Cancer Center show that immunotherapy doesn't necessarily worsen complications for patients with both COVID-19 and cancer. (2020-07-20)
Beautyberry leaf extract restores drug's power to fight 'superbug'
Laboratory experiments showed that the plant compound works in combination with oxacillin to knock down the resistance to the drug of methicillin-resistant Staphylococcus aureus, or MRSA. (2020-07-16)
Blueprint of oxytocin receptor facilitates development of new autism drugs
Oxytocin plays a role in various mental health and sexual reproduction disorders. (2020-07-15)
New french prescribing rules result in decreased prescribing of certain sleep drugs
In France, the implementation of new prescribing rules for the sedative-hypnotic drug zolpidem led to an important and immediate decrease in use. (2020-07-14)
TGen identifies immune effects of drug in aggressive ovarian cancer striking young women
A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by TGen. (2020-07-10)
Ceftolozane/tazobactam: New treatment option for severe infections, but no proof of superiority
Ceftolozane/tazobactam: new treatment option for severe infections, but no proof of superiority New antibiotic broadens the treatment options for severe infections and resistances. (2020-07-02)
Popular chemotherapy drug may be less effective in overweight and obese women
Breast cancer patients who are overweight or obese might benefit less from treatment with docetaxel, a common chemotherapy drug, than lean patients, a new study finds. (2020-07-02)
High-end microscopy refined
New details are known about an important cell structure: For the first time, two Würzburg research groups have been able to map the synaptonemal complex three-dimensionally with a resolution of 20 to 30 nanometres. (2020-07-01)
Cancer cells make blood vessels drug resistant during chemotherapy
Scientists have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance. (2020-07-01)
The combination of four drugs at low doses is more effective in the treatment of a lu
The study, published in the Nature Communications journal, and led by the Netherlands Cancer Institute (NKI), has had the collaboration of researchers from IDIBELL/ICO and HUB. (2020-07-01)
Yale Cancer Center study validates combination therapy for aggressive endometrial cancer
Yale Cancer Center (YCC) scientists have found that combining the targeted drug trastuzumab with chemotherapy significantly improves survival rates for women with a rare, aggressive form of endometrial cancer. (2020-06-29)
New class of precision medicine strips cancer of its DNA defenses
A new precision medicine targeting cancer's ability to repair its DNA has shown promising results in the first clinical trial of the drug class. (2020-06-22)
New nanoparticle drug combination for atherosclerosis
Physicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation. (2020-06-17)
Drug with new approach on impeding DNA repair shows promise in first clinical trial
Berzosertib, an ATR-targeting drug, improves progression-free survival in combination with chemotherapy in patients with high-grade serous ovarian cancer. (2020-06-15)
Addressing the drug problem in health and social care will produce better outcomes
Researchers at the Finnish Institute for Health and Welfare (THL) have evaluated the impact of decriminalization policy in different settings. (2020-06-12)
A compound unlike any other
A compound discovered in the gills of wood-eating clams could be the solution to a group of parasites responsible for some of the world's most common infections. (2020-06-11)
Chemotherapy/immunotherapy combo shows promise for first-line treatment of mesothelioma
Inoperable malignant pleural mesothelioma, is a rare and aggressive cancer of the protective lining of the lungs, or pleura, often caused by exposure to asbestos. (2020-06-11)
Yale researchers find potential treatment for Rett Syndrome
An experimental cancer drug can extend the life of mice with Rett Syndrome, a devastating genetic disorder that afflicts about one of every 10,000 to 15,000 girls within 6 to 18 months after birth, Yale researchers report June 10 in the journal Molecular Cell. (2020-06-10)
BU researcher: Screening for drug use can be reasonable, but not evidence-based
In the June 9 issue of JAMA, the US Preventive Services Task Force (USPSTF) recommends that clinicians screen for unhealthy drug use (that is, any use of drugs that are illegal or medications not used for medical purposes) for all adult patients, but admits that there is still little evidence weighing the benefits and risks of this practice. (2020-06-09)
University of Cincinnati research points to potential new treatment for pancreatic cancer
As the next step in finding a potential targeted treatment for pancreatic cancer, researchers at the University of Cincinnati are publishing a new study revealing how a combination therapy may improve outcomes for patients with this disease. (2020-06-08)
Ribociclib in breast cancer: Added benefit for certain women after menopause
After expiry of the G-BA decisions, IQWiG reassessed the drug in two combinations. (2020-06-05)
Advances in nanoparticles as anticancer drug delivery vector: Need of this century
This review article provides a summary of current advances in the use of nanoparticles (NPs) as anticancer drug-delivery vectors. (2020-06-04)
Widely available indigestion drug may curb COVID-19 symptoms in mild to moderate disease
A widely available and inexpensive drug that is used to ease the symptoms of indigestion may prove a worthy contender for treating COVID-19 infection in those whose disease doesn't require admission to hospital, suggest the findings of a small case series, published online in the journal Gut. (2020-06-04)
Cognitive behavior therapy tops other psychotherapies in reducing inflammation
A review of 56 randomized clinical trials finds that psychological and behavioral therapies may be effective non-drug treatments for reducing disease-causing inflammation in the body. (2020-06-03)
New drug combinations help overcome resistance to immunotherapy
A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way. (2020-05-28)
Two paths better than one for treating patients with heart stents
Pairing a blood-thinning drug with aspirin daily for patients who have an angioplasty with a stent can contribute to better health outcomes, including lower risk of death, than aspirin alone, according to a recent study by cardiologists at the University of Alberta and Mazankowski Alberta Heart Institute. (2020-05-28)
Study finds surge in hydroxychloroquine/chloroquine prescriptions during COVID-19
A new study by investigators from Brigham and Women's Hospital examines changes in prescription patterns in the United States during the COVID-19 pandemic. (2020-05-28)
Nordic countries struggle with a severe drug overdose problem
Despite the fact that the Nordic countries are often seen as ideal in practically every global ranking of quality of life and social equality, the number of drug-related deaths in these countries are among the highest in Europe. (2020-05-27)
New cancer immunotherapy targeting myeloid cells slows tumor growth
Checkpoint inhibitors, a type of immunotherapy, that target myeloid immune cells and slow tumor growth were discovered by a team from the Perelman School of Medicine at the University of Pennsylvania and other institutions. (2020-05-27)
Target trials support drug safety in pregnant patients
Out of concern for fetal safety, pregnant people have typically been excluded from drug trials. (2020-05-27)
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