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Current Drug development News and Events

Current Drug development News and Events, Drug development News Articles.
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'Trojan horse' anticancer drug disguises itself as fat
A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors. (2019-07-18)
Heart drug could increase survival rates for children with aggressive form of brain tumor
Researchers at the University of Nottingham have discovered that repurposing a heart drug could significantly increase the survival rate for children with ependymoma - a type of brain tumour. (2019-07-16)
An entry to optically active oxazolidinones: The use of neutral phosphonium salt catalysts
Oxazolidinones are coveted in the field of pharmacology for their bioactive properties. (2019-07-12)
Early benefit assessment reveals weaknesses in the development of new drugs
In the British Medical Journal, IQWiG researchers analyse the first 216 AMNOG assessments of new drugs and derive proposals for more targeted drug development. (2019-07-11)
Scientists opening the door to a new era of medicinal chemistry
A new molecular descriptor estimates molecular complexity and defines the evolution of small molecules in medicinal chemistry. (2019-07-11)
Larger drug trials that intervene earlier needed for Alzheimer's disease
There are currently no drugs that stop or inhibit Alzheimer's disease. (2019-07-10)
No evidence of added benefit for most new drugs, say researchers
More than half of new drugs entering the German healthcare system have not been shown to add benefit, argue researchers in The BMJ today. (2019-07-10)
Metabolic reprogramming of branched-chain amino acid facilitates drug resistance in lung cancer
Research teams led by Dr. Ji Hongbin at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences, Dr. (2019-07-09)
New method reveals how well TB antibiotics reach their targets
Scientists have developed a new technique that enables them to visualise how well antibiotics against tuberculosis (TB) reach their pathogenic targets inside human hosts. (2019-06-27)
SLAS Discovery announces its July feature article, '3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis'
In July's SLAS Discovery feature article, '3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis,' Tijmen H. (2019-06-24)
Reconfigurable multi-organ-on-a-chip system reliably evaluates chemotherapy toxicity
Christopher McAleer and colleagues have created a new multiorgan-on-a-chip system that can accurately capture the toxic effects of chemotherapies that have been metabolized by the liver -- effects usually not seen in standard cell culture preclinical drug development. (2019-06-19)
New methods from material sciences in physics find their way into cancer research
A new study on the behavior of water in cancer cells shows how methods usually limited to physics can be of great use in cancer research. (2019-06-18)
Stem cells reprogrammed into neurons could reveal drugs harmful to pregnancy
Soham Chanda, an assistant professor in the Department of Biochemistry and Molecular Biology, has designed a new experimental system that can rapidly assess the pathogenic effects of a drug on a baby's developing brain. (2019-06-17)
Researchers develop drug-targeting molecules to improve cancer treatment
A compound was developed from a new material, described as an easily injected hydrogel, which acts as a 'homing' cue to attract drug molecules to sites bearing a tumor. (2019-06-12)
Proof of sandwiched graphene-membrane superstructure opens up a membrane-specific drug delivery mode
Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Tsinghua University (THU) proved a sandwiched superstructure for graphene oxide (GO) that transport inside cell membranes for the first time. (2019-06-07)
Stellenbosch University researchers study resistance to 'protect' anti-TB drug
Scientists from Stellenbosch University are trying to conserve the life-saving treatment bedaquiline, by studying how the bacterium that causes TB can develop resistance to this drug. (2019-05-30)
How bacteria acquire antibiotic resistance in the presence of antibiotics
A new study's disconcerting findings reveal how antibiotic resistance is able to spread between bacteria cells despite the presence of antibiotics that should prevent them from growing. (2019-05-23)
New method simplifies the search for protein receptor complexes, speeding drug development
A a new method of assessing the actions of medicines by matching them to their unique protein receptors has the potential to greatly accelerate drug development and diminish the number of drug trials that fail during clinical trials. (2019-05-20)
Early in vitro testing for adverse effects on embryos
ETH researchers have combined embryonic cells and liver cells in a new cell culture test. (2019-05-14)
Researchers identify faster, more effective drug combinations to treat tuberculosis
Study describes a way to reduce the duration of tuberculosis treatment by using an approach called 'artificial intelligence-parabolic response surface' that allows researchers to quickly identify three or four drug combinations among billions of possible combinations to treat TB up to five times faster than current therapies. (2019-05-14)
DGIST acquired the first KELAF Certification as a Daegu-Gyeongbuk Educational Institution
Designated as a KELAF and held signboard hanging ceremony as organized by the Ministry of Drug and Food Safety. (2019-05-08)
New approach to drug discovery could lead to personalized treatment of neuropsychiatric disorders
Researchers have developed a method that could drastically accelerate the search for new drugs to treat mental health disorders such as schizophrenia. (2019-05-08)
Huntington drug successfully lowers levels of disease-causing protein
An international clinical trial has found that a new drug for Huntington disease is safe, and that treatment with the drug successfully lowers levels of the abnormal protein that causes the debilitating disease in patients. (2019-05-06)
External reference drug pricing could save Medicare tens of billions
A new study by researchers at the Johns Hopkins Bloomberg School of Public Health found that prices for brand-name prescription drugs averaged 3.2 to 4.1 times higher in the US when compared with prices in the United Kingdom, Japan and the Canadian province of Ontario. (2019-05-06)
New digital filter approach aims to improve chemical measurements
A Purdue University professor and expert in measurement science has led a team to design a new filter aimed at helping drug developers and researchers create more exact measurements early in the drug development stage, which can ultimately help move a drug to clinical trials faster. (2019-05-02)
BU researchers investigate differences in coatings of drug-coated balloon catheters
Drug-coated balloon catheters to open narrowed blood vessels and to deliver drugs to the impacted sites are used frequently for the treatment of peripheral arterial disease. (2019-05-02)
Are Canadians kept in the dark about new risks of medicines?
Government warnings about potential drug safety risks vary significantly across countries, according to a new international study co-authored by researchers at the University of British Columbia. (2019-04-29)
More evidence that blood tests can detect the risk of Alzheimer's
A new study confirms that a simple blood test can reveal whether there is accelerating nerve cell damage in the brain. (2019-04-23)
Scanning for cancer treatment
11,000 people are predicted to die from acute myeloid leukemia (AML) in 2019. (2019-04-15)
Quashing the resistance: MicroRNA regulates drug tolerance in subset of lung cancers
Relapse of disease following conventional treatments remains one of the central problems in cancer management, yet few therapeutic agents targeting drug resistance and tolerance exist. (2019-04-08)
Study identifies gender differences in reported adverse drug reactions
In a British Journal of Clinical Pharmacology study, investigators uncovered numerous gender differences in reports of adverse drug reactions sent to the National Pharmacovigilance Centre in the Netherlands. (2019-04-03)
Research into tropical eye worm yields new tests to assess safety of anti-filarial drugs
Researchers at the LSTM's Centre for Drugs and Diagnostics, and University of Buea, Cameroon have developed new models of the tropical eye worm, Loa loa for the development of new drugs against filariasis. (2019-03-29)
Smarter drug release thanks to control over encapsulation
Researchers at Eindhoven University of Technology and Utrecht University have discovered the parameters that govern the encapsulation of drugs. (2019-03-19)
Drug that prevents lung problems in older preemies also lowers costs
A drug given to nearly 10 percent of all pregnant women to prevent severe respiratory ailments in preterm babies also reduces healthcare costs, according to a new study by Columbia researchers. (2019-03-13)
Cell study reveals key mechanism linked to healthy development
Researchers have uncovered details of the role played by a key biological component involved in healthy cell development. (2019-03-07)
American drug overdose death rates the highest among wealthy nations, USC study finds
A USC study found that the United States has the highest drug overdose death rates among a set of high-income countries. (2019-02-21)
Is the drug overdose epidemic unique to the United States?
Is the current American drug overdose epidemic an isolated phenomenon? (2019-02-21)
Complex medication regimens are common & sometimes dangerous in patients with lung disease
Patients with interstitial lung disease -- a group of disorders causing progressive scarring of lung tissue -- are often prescribed various medications that specifically target their disease and others that treat their symptoms. (2019-02-21)
Cocktail of common antibiotics can fight resistant E. coli
Scientists from the Novo Nordisk Foundation Center for Biosustainability have discovered that a combination of two common antibiotics is able to eliminate multi-drug resistant E. coli causing urinary tract infections. (2019-02-20)
UTMB develops drug to rejuvenate muscle cells
Researchers from The University of Texas Medical Branch at Galveston have developed a promising drug that has proven to significantly increase muscle size, strength and metabolic state in aged mice, according to a study just published in Biochemical Pharmacology. (2019-02-15)
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