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Current Drug resistance News and Events

Current Drug resistance News and Events, Drug resistance News Articles.
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New drug combinations help overcome resistance to immunotherapy
A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way. (2020-05-28)
Researchers track how bacteria purge toxic metals
Cornell researchers combined genetic engineering, single-molecule tracking and protein quantitation to get a closer look at this mechanism and understand how it functions. (2020-05-28)
Nordic countries struggle with a severe drug overdose problem
Despite the fact that the Nordic countries are often seen as ideal in practically every global ranking of quality of life and social equality, the number of drug-related deaths in these countries are among the highest in Europe. (2020-05-27)
Target trials support drug safety in pregnant patients
Out of concern for fetal safety, pregnant people have typically been excluded from drug trials. (2020-05-27)
Anti-malarial drug shows promise for brain cancer treatment
Glioblastoma multiforme (GBM) is an aggressive form of cancer in the brain that is typically fatal. (2020-05-26)
Mechanism underlying the development of diabetes and fatty liver illuminated
Non-alcoholic steatohepatitis (NASH) is a chronic liver disease often associated with diabetes. (2020-05-22)
Insight into mechanism of treatment-resistant gonorrhea sets stage for new antibiotics
Medical University of South Carolina researchers investigated the effects of mutations altering the structure of an essential protein in an antibiotic-resistant strain of Neisseria gonorrhoeae. (2020-05-22)
Scientists identify chemicals in noxious weed that 'disarm' deadly bacteria
Scientists have identified specific compounds from the Brazilian peppertree -- a weedy, invasive shrub in Florida -- that reduce the virulence of antibiotic-resistant staph bacteria. (2020-05-21)
Genetic tradeoffs do not stop evolution of antibiotic resistance
Bacteria can still develop antibiotic resistance even in the face of challenging genetic tradeoffs, or compromises, associated with varying antibiotic concentrations, says a new study published today in eLife. (2020-05-19)
Study finds some reductions in community antibiotic resistant infections and dispensing
A study by academics at the University of Bristol has found reductions in overall and individual antibiotic dispensing between 2013 and 2016 after evaluating, for the first time, national primary care prescribing policy on community antibiotic resistant infection. (2020-05-19)
Discovery of high-Chern-number and high-temperature Chern insulator states: to information highway
One of the most important issues in physical science and low-consumption electronics is how to realize multiple dissipationless edge channels (high Chern number) and increase the working temperature in Chern insulators. (2020-05-17)
'Cells-soldiers' turned to be more resistant than 'cells-combat medics'
Researchers from Sechenov University (Russia) and University of Pittsburgh (USA) discovered that the resistance of innate immune cells, macrophages, to ferroptosis -- a type of programmed cell death -- depends on the type of their activation. (2020-05-16)
Researchers find one-two punch may help fight against Salmonella
Researchers found that dephostatin does not kill Salmonella or stop it from growing. (2020-05-14)
Research shows fungicides effective in fighting Fusarium wilt of watermelon
Fusarium wilt is one of the most economically important diseases of watermelon and a major problem to growers worldwide. (2020-05-14)
Brief intervention could keep lower-risk drug use from becoming riskier: BU study
A new pilot randomized trial by researchers from the Boston University School of Public Health (BUSPH) and School of Medicine (BUSM) and Boston Medical Center (BMC) finds that a brief intervention for people with lower-risk drug use may help prevent increased and riskier use, as well as other health issues. (2020-05-11)
University of Toledo scientists discover new targets for preventing damage from viral infections
When the body faces stressful conditions such as high temperatures or lack of nutrients, cells produce the same large structures they make to combat virus infections. (2020-05-11)
Insulin resistance contributes to racial disparities in breast cancer prognosis in US women, Mount Sinai researchers reveal
New study identifies that differences in insulin resistance can explain in part the disparities in breast cancer survival between black and white women. (2020-05-11)
Better antibiotic dosing could save lives in ICU
More lives could be saved in intensive care units around the world if new antibiotic guidelines designed by The University of Queensland are adopted. (2020-05-08)
Hygiene reduces the need for antibiotics by up to 30%
A new paper published in the American Journal of Infection Control (AJIC), finds improved everyday hygiene practices, such as hand-washing, reduces the risk of common infections by up to 50%, reducing the need for antibiotics, by up to 30%. (2020-05-07)
SMART researchers uncover new anti-phage defence mechanisms in bacteria
Researchers at Singapore-MIT Alliance for Research and Technology (SMART), Wuhan University, Shanghai Jiao Tong University, and Tsinghua University have discovered a previously unknown anti-phage defence mechanism in some bacteria that uses unique new ways to protect itself against phages. (2020-05-06)
Public would obey major changes to antibiotic advice, research shows
The public would comply with major changes to medical advice - but would then be less likely to follow other new guidelines in the future, research shows. (2020-05-06)
Worms freeload on bacterial defence systems
Scientists have untangled a sensory circuit in worms that allows them to choose whether to spend energy on self-defence or rely on the help of nearby bacteria, a new study in eLife reveals. (2020-05-05)
MU researcher identifies four possible treatments for COVID-19
While COVID-19 has infected millions of people worldwide and killed hundreds of thousands, there is currently no vaccine. (2020-05-04)
Research shows relationship between trophic type and latent period in fungal pathogens
Through a meta-analysis of biotrophs, hemibiotrophs, and necrotophs, four scientists set out to find if the latent period of leaf fungal pathogens reflects their trophic types. (2020-05-04)
Long-lasting, low toxicity antimicrobial peptide fights 'superbug' lung infections
Through serendipity, researchers considerably reduced the toxicity of a potential antibiotic against the most feared drug-resistant bacteria, while also improving its stability in fighting infections. (2020-05-01)
Schizophrenia drug combined with radiation shows promise in treating deadly brain tumors
UCLA researchers found adding a drug once commonly used to treat schizophrenia to traditional radiation therapy helped improve overall survival in mice with glioblastoma. (2020-05-01)
Fecal transplantation improves outcomes in patients with multi-drug resistant organisms
Transferring fecal matter from the digestive systems of healthy donors to extremely ill patients who had previously been infected with drug-resistant bacteria resulted in shorter hospital stays, fewer bloodstream infections and infections that were easier to treat, according to research that was selected for presentation at Digestive Disease Week® (DDW) 2020. (2020-04-30)
Understanding the diversity of cancer evolution based on computational simulation
Understanding the principles of cancer evolution is important in designing a therapeutic strategy. (2020-04-30)
Lipophilic guanylhydrazone analogues as promising trypanocidal agents: An extended SAR study
In this report, a team of researchers lead by Dr. (2020-04-30)
UBC discovery opens new avenues for designing drugs to combat drug-resistant malaria
For the first time, UBC researchers have shown a key difference in the three-dimensional structures of a key metabolic enzyme in the parasite that causes malaria compared to its human counterpart. (2020-04-30)
To prevent antimicrobial resistance, vaccinate the world's kids
Childhood vaccination may be a powerful tool in the fight against antimicrobial resistance in low- and middle-income countries, finds a new analysis led by researchers University of California, Berkeley. (2020-04-29)
New insight into bacterial structure to help fight against superbugs
Scientists from the University of Sheffield have produced the first high-resolution images of the structure of the cell wall of bacteria, in a study that could further understanding of antimicrobial resistance. (2020-04-29)
New drug formulation could treat Candida infections
With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections. (2020-04-28)
New understanding of asthma medicines could improve future treatment
New research has revealed new insights into common asthma aerosol treatments to aid the drug's future improvements which could benefit hundreds of millions of global sufferers. (2020-04-27)
Antibiotic exposure can 'prime' single-resistant bacteria to become multidrug-resistant
Researchers at the University of Washington and the University of Idaho report that, for a bacterial pathogen already resistant to an antibiotic, prolonged exposure to that antibiotic not only boosted its ability to retain its resistance gene, but also made the pathogen more readily pick up and maintain resistance to a second antibiotic and become a dangerous, multidrug-resistant strain. (2020-04-27)
Breakthrough discovery in HIV research opens path to new, better therapies
Cells infected with HIV make two forms of the virus's RNA. (2020-04-23)
Game theory suggests more efficient cancer therapy
Cornell mathematicians are using game theory to model how this competition could be leveraged, so cancer treatment -- which also takes a toll on the patient's body -- might be administered more sparingly, with maximized effect. (2020-04-23)
Scientists uncover major cause of resistance in solid electrolytes
Scientists investigated grain boundaries in a solid electrolyte at an unprecedentedly small scale. (2020-04-21)
Aquaculture at the crossroads of global warming and antimicrobial resistance
Antimicrobial resistance is responsible for some 700 000 deaths each year worldwide. (2020-04-20)
What's old is new again
Drug resistance is a major obstacle in cancer treatment--leading to relapse for many patients. (2020-04-20)
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