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Current Drug resistance News and Events

Current Drug resistance News and Events, Drug resistance News Articles.
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ECDC: Study shows gaps in healthcare workers' knowledge and attitudes about antibiotics
Knowledge and awareness of antibiotic resistance and related issues is generally high among European healthcare workers, according to the first European survey to examine attitudes and behaviours in relation to antibiotic resistance in this group. (2019-11-18)
Blocking a survival mechanism could tackle melanoma treatment resistance
The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the 'survival system' of cancer cells according to a study published in Nature Communications today. (2019-11-14)
A step closer to cancer precision medicine
Researchers from the Faculty of Medicine and the Institute for Molecular Medicine (FIMM) at the University of Helsinki have developed a computational model, Combined Essentiality Scoring (CES) that enables accurate identification of essential genes in cancer cells for development of anti-cancer drugs. (2019-11-14)
Research reveals new state of matter: a Cooper pair metal
In a finding that reveals an entirely new state of matter, research published in the journal Science shows that Cooper pairs, electron duos that enable superconductivity, can also conduct electricity like normal metals do. (2019-11-14)
Novel mathematical framework provides a deeper understanding of how drugs interact
Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have developed a new methodology characterizing more precisely how drugs influence each other when combined during treatment. (2019-11-13)
Leukaemia cells can transform into non-cancerous cells through epigenetic changes
Researchers of the Josep Carreras Leukaemia Research Institute discover that a leukaemic cell is capable of transforming into a non-cancerous cell through epigenetic changes. (2019-11-13)
High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers
78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment. (2019-11-13)
Discovery: New biomarker for cancer stem cells
A University of Houston College of Pharmacy associate professor has discovered a new biomarker in cancer stem cells that govern cancer survival and spread, and it's raising hope that drug discovery to kill cancer stem cells could follow suit. (2019-11-13)
Antimicrobial resistance poses significant risk to people, the economy
CCA expert panel study provides new data on potential impact of antimicrobial resistance in Canada. (2019-11-12)
Researchers strengthen weakest link in manufacturing strong materials
Industrial and automotive machinery, such as automotive engine parts, contain materials that are, heat-, wear-, and corrosion-resistant. (2019-11-12)
Wildlife in Catalonia carry bacteria resistant to antimicrobials used in human health
A study performed in Catalonia by IRTA-CReSA, UAB and Torreferrussa Wildlife Center demonstrates that the enteric bacteria of wildlife origin in Catalonia exhibits a high prevalence and diversity of antibiotic resistance genes. (2019-11-12)
Boosting host immune defenses to treat tuberculosis
A study in iScience suggests a new approach that might help treat Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis: making people's cells better at killing Mtb by harnessing RNA sensors in our cells, which detect the RNA of invading pathogens. (2019-11-12)
Drug discount cards could actually cost patients more
New research published today in the Canadian Medical Association Journal (CMAJ) reveals that brand-name drug discount cards are leading to higher health care spending in Canada -- increased costs that are ultimately passed on to patients. (2019-11-11)
Antibiotics: New substances break bacterial resistance
Researchers at the Martin Luther University Halle-Wittenberg (MLU) have developed a new, promising class of active ingredients against resistant bacteria. (2019-11-11)
Fingerprint test can distinguish between those who have taken or handled heroin
A state-of-the-art fingerprint detection technology can identify traces of heroin on human skin, even after someone has washed their hands -- and it is also smart enough to tell whether an individual has used the drug or shaken hands with someone who has handled it. (2019-11-11)
Lower IQ, family history tied to treatment-resistant schizophrenia
Those with a family history of schizophrenia and men with lower IQ are more likely to struggle with treatment resistant schizophrenia than others with the mental disorder, according to a study by researchers at Karolinska Institutet in Sweden published in the journal Molecular Psychiatry. (2019-11-11)
Investigators build a better targeted drug therapy using the power of computation
Investigators from Brigham and Women's Hospital set out to design more stable and predictable ADCs by using computer simulations to predict and plan out how the drug payload and antibody can stay linked to each other. (2019-11-08)
Study provides insights on the effects of cannabidiol on severe form of epilepsy
Results from a study published in the British Journal of Clinical Pharmacology may help explain why cannabidiol -- a chemical component of marijuana with no psychoactive properties -- reduces the frequency of seizures in patients with a severe form of epilepsy. (2019-11-07)
NUS researchers discover enzyme's role in 'natural killer T cell lymphoma'
Researchers from the Cancer Science Institute of Singapore uncovered an enzyme which could serve as a potential biomarker for 'natural killer T cell lymphoma' and could lead to new targeting routes for treatment. (2019-11-07)
Liver-chip predicts the toxicity of drug candidates across species
Researchers have created a 'Liver-Chip' using Organs-on-Chips technology that can predict and characterize the liver toxicity of various drug candidates and compounds in rats, dogs, and humans. (2019-11-06)
Poll reveals older adults' risky use of antibiotics, opportunities to improve prescribing
Half of older Americans got help from the infection-fighting power of antibiotics in the past 2 years, a new poll finds, but a sizable minority didn't follow the instructions on their pill bottle. (2019-11-04)
Diabetes drug relieves nicotine withdrawal
A drug commonly used to treat Type II diabetes abolishes the characteristic signs of nicotine withdrawal in rats and mice, according to new research published in JNeurosci. (2019-11-04)
Chemotherapy sometimes set the stage for drug-resistant leukemia at relapse
An international collaboration has identified therapy-induced, drug-resistance mutations in children with acute lymphoblastic leukemia who relapse. (2019-11-01)
Fluorescent probes offer fuller view of drug delivery in cells
Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside living cells. (2019-11-01)
'Wolves in sheep's clothing' -- the superbugs outsmarting laboratory tests
Hospital screening tests are failing to identify the true extent of microbial resistance, according to new research. (2019-10-29)
New insight on how bacteria evolve drug resistance could lead to improved antibiotic therapies
Researchers have provided new insight into a mechanism behind the evolution of antibiotic resistance in a type of bacterium that causes severe infections in humans. (2019-10-29)
Drug overdose deaths in CT doubled in 6 years
Opioid overdose deaths in Connecticut doubled in the past 6 years, largely driven by use of multiple drugs together, according to a team of researchers from the University of Connecticut and Yale University. (2019-10-29)
Advanced cancer drug shrinks and intercalates DNA
A new study published in EPJ E has found that the drug first forces itself between the strands of the DNA molecule's double helix, prising them apart. (2019-10-28)
Deleting a liver enzyme lowers the health risk of sweet treats (at least in mice)
Hepatic insulin resistance, caused by diets high in sugar and fat, can lead to type 2 diabetes. (2019-10-24)
Bacterial lifestyle alters the evolution of antibiotic resistance
How bacteria live - whether as independent cells or in a communal biofilm - determines the course of their evolution, with implications for drug-resistant infections. (2019-10-23)
New chemical weapon to combat cancer
Patients often suffer from side effects due to the doses used in the treatments for fighting cancer. (2019-10-23)
Yeast study reveals how multiple genes interact to influence a surprising cellular outcome
The research lays ground for understanding how genes interact in higher order combinations as is the case with most diseases (2019-10-23)
Evolving alongside other bacteria keeps hospital bug potent
Bacteria that evolve in natural environments -- rather than laboratory tests -- may become resistant to phage treatments without losing their virulence, new research shows. (2019-10-23)
Antibiotics with novel mechanism of action discovered
Many life-threatening bacteria are becoming increasingly resistant to existing antibiotics. (2019-10-23)
Rapid triage test sniffs out active tuberculosis infections in adults
A new triage test for human blood samples can distinguish active cases of tuberculosis (TB) from similar diseases in adults in less than an hour -- helping to meet an elusive goal for global health authorities. (2019-10-23)
A 'shocking' new way to treat infections
New research from the University of Pittsburgh's Swanson School of Engineering introduces a revolutionary treatment for these infections. (2019-10-22)
Study shows metformin offers no strength training benefits for seniors
A clinical trial initiated by University of Kentucky researchers argues against the hypothesis that the diabetes drug metformin could help exercising seniors gain more muscle mass. (2019-10-22)
Single mutation dramatically changes structure and function of bacteria's transporter proteins
Swapping a single amino acid in a simple bacterial protein changes its structure and function, revealing the effects of complex gene evolution, finds a new study published in the journal eLife. (2019-10-22)
New strategy for treating high blood pressure
The key to treating blood pressure might lie in people who are 'resistant' to developing high blood pressure even when they eat high salt diets, shows new research published today in Experimental Physiology. (2019-10-22)
Researchers identify a new way to target treatment-resistant cancers
An international team of researchers has found a different way cancer becomes resistant to chemotherapy, suggesting a new target for drugs. (2019-10-21)
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