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Current Enzyme News and Events, Enzyme News Articles.
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Nanopore reveals shape-shifting enzyme linked to catalysis
University of Groningen scientists observed the characteristics of a single enzyme inside a nanopore. (2020-04-06)
Potential therapy for rare neurologic disease
A targeted therapy, currently being studied for treatment of certain cancers including glioblastoma, may also be beneficial in treating other neurologic diseases, a study at the University of Cincinnati shows. (2020-04-06)
Gut enzyme IAP found to prevent aging and frailty in animal models
Studying mice and fruitflies, researchers found that the enzyme intestinal alkaline phosphotase helped prevent intestinal permeability and gut-derived systemic inflammation, resulting in less frailty and extended life span. (2020-03-26)
Unconstrained genome targeting with CRISPR-Cas9 variants less reliant on PAM
Addressing a fundamental limitation in CRISPR-Cas genome editing, researchers have developed new engineered Cas9 variants that nearly eliminate the need for a protospacer adjacent motif known as PAM. (2020-03-26)
Bacterial enzyme could become a new target for antibiotics
Scientists discover the structure of an enzyme, found in the human gut, that breaks down a component of collagen. (2020-03-17)
Highly efficient, low-cost method developed to reduce DNA errors
A team of researchers from the Chinese Academy of Science (CAS) has developed a more efficient and cost-effective way to accurately synthesize DNA than traditionally used methods. (2020-03-16)
Dr. Jekyll and Mr. Hyde -- Enzyme targeted by TB antibiotic later stops the drug destroying it
Crick and Imperial researchers have found that a key antibiotic widely used to treat drug-resistant tuberculosis does not work as expected - a finding which could be used to develop new drugs. (2020-03-16)
How sperm unpack dad's genome so it can merge with mom's
UC San Diego researchers discover the enzyme SPRK1's role in reorganizing the paternal genome during the first moments of fertilization -- a finding that might help explain infertility cases of unknown cause. (2020-03-13)
Scientists visualize the structure of a key enzyme that makes triglycerides
The first structure of a lipin enzyme, which carries out an important step in the production of triglycerides, the main reservoir for long-term energy storage, will help scientists to better understand how lipins regulate the production of triglycerides. (2020-03-11)
NIH researchers successfully stop blood vessel, tumor growth in mice
Scientists at the National Institutes of Health and other institutions have devised a new strategy to stop tumors from developing the new blood vessels they need to grow. (2020-03-11)
Sensing infection, suppressing regeneration
UIC researchers describe an enzyme that blocks the ability of blood vessel cells to self-heal. (2020-03-11)
Advanced optical imaging technique may lead to structure-guided drug design
A Clemson University biophysics faculty member and a team of international researchers have developed and demonstrated a new optical imaging method to monitor a single molecule in action. (2020-03-09)
Mayo Clinic-led study links obesity with pancreatitis
A study by researchers at Mayo Clinic in Arizona published in the The Journal of Clinical Investigation has found that obesity is not only implicated in chronic diseases such as diabetes, but also in sudden-onset diseases such as pancreatitis. (2020-03-09)
Unexpected discovery: Blue-green algae produce oil
Cyanobacteria -- colloquially also called blue-green algae - can produce oil from water and carbon dioxide with the help of light. (2020-03-05)
Plasma-driven biocatalysis
Compared with traditional chemical methods, enzyme catalysis has numerous advantages. (2020-03-03)
Chemists inhibit a critical gear of cell immortality
Researchers have developed a promising molecular tool that targets and inhibits one of cell immortality's underlying gears: the enzyme telomerase. (2020-03-03)
New Cas9 variant makes genome editing even more precise
Researchers develop more specific CRISPR-Cas9 gene scissors. (2020-03-03)
'Optical tweezers' help in quest for better cancer treatments
In a groundbreaking new study, an interdisciplinary team of Michigan State University researchers has observed telomerase activity at a single-molecule level with unprecedented precision -- expanding our understanding of the vital enzyme and progressing toward better cancer treatments. (2020-03-03)
Monash researchers discover fainting disorder drug
Monash University researchers have revealed a novel therapy that corrects the mechanism in the body that's gone wrong in Postural Orthostatic Tachycardia Syndrome (POTS), the condition affecting the former lead singer of The Wiggles. (2020-03-03)
Whether horseradish flea beetles deter predators depends on their food plant and their life stage
Horseradish flea beetles use glucosinolates from their host plants for their own defense. (2020-03-02)
How enzymes build sugar trees
Researchers have used cryo-electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. (2020-02-27)
Study sheds light on how a drug being tested in COVID-19 patients works
As hospitalized COVID-19 patients undergo experimental therapy, research published in the Journal of Biological Chemistry explains how the drug, remdesivir, stops replication in coronaviruses. (2020-02-27)
Stem cell transplants in utero offers TX for metabolic disorders that often end pregnancy
Administering stem cell or enzyme therapy in utero may be a path to alleviating some congenital diseases that often result in losing a pregnancy, according to a new study in mice by UC San Francisco researchers, who showed that stem cells can enter the fetal brain during prenatal development and make up for cells that fail to make an essential protein. (2020-02-26)
Scientists develop enzyme produced from agricultural waste for use as laundry detergent
An international team of researchers has developed an enzyme produced from agricultural waste that could be used as an important additive in laundry detergents. (2020-02-25)
Shaping the rings of molecules
Canadian chemists discover a natural process to control the shape of 'macrocycles,' molecules of large rings of atoms, for use in pharmaceuticals and electronics. (2020-02-21)
New probe developed to detect a common target of anti-inflammatory drugs
Researchers at the Beckman Institute for Advanced Science and Technology have recently developed a new probe to detect the activity of Cyclooxygenase-2, an enzyme that plays a major role in driving the progression of cancer. (2020-02-21)
Atomic structures mapped in measles, mumps, flu and RSV
Northwestern University researchers have, for the first time, determined the 3D atomic structure of a key complex in paramyxoviruses, a family of viruses that includes measles, mumps, human parainfluenza and respiratory syncytial virus (RSV). (2020-02-17)
New gene mutation associated with Fabry cardiomyopathy
The A143T variant of the GLA gene is associated with an increased risk of Fabry cardiomyopathy, according to a new study. (2020-02-13)
Understanding how a protein wreaks havoc in the brain in Parkinson's disease
Parkinson's disease is a long-term (chronic) neurological condition that affects the way the brain co-ordinates body movements like walking and talking, as well as cognitive abilities. (2020-02-13)
Mathematical model reveals behavior of cellular enzymes
Mathematical modeling helps researchers to understand how enzymes in the body work to ensure normal functioning. (2020-02-13)
Cracking the code for hookworm infestation
Monash University researchers have uncovered a key way that hookworms evade the immune system - providing new hope in the search for a vaccine. (2020-02-12)
First artificial enzyme created with two non-biological groups
Scientists at the University of Groningen turned a non-enzymatic protein into a new, artificial enzyme by adding two abiological catalytic components: an unnatural amino acid and a catalytic copper complex. (2020-02-10)
The invisibility cloak of a fungus
The human immune system can easily recognize fungi because their cells are surrounded by a solid cell wall of chitin and other complex sugars. (2020-02-05)
Novel compound is promising drug candidate for Alzheimer's disease
As published today in the Royal Society of Chemistry's Chemical Communications, a compound known as 'C1' uses a novel mechanism to efficiently prevent the enzyme gamma-secretase from producing amyloids. (2020-02-03)
Structural biology: Special delivery
Bulky globular proteins require specialized transport systems for insertion into membranes. (2020-02-03)
DNA extracted in museum samples can reveal genetic secrets
DNA in preserved museum specimens can allow scientists to explore the history of species and humanities impact on the ecosystem, but samples are typically preserved in formaldehyde which can damage DNA and make very difficult to recover. (2020-01-31)
Research team finds possible new approach for sleeping sickness drugs
Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei. (2020-01-30)
How HIV develops resistance to key drugs discovered
The mechanism behind how HIV can develop resistance to a widely-prescribed group of drugs has been uncovered by new research from the Crick and Dana-Farber Cancer Institute, with the findings opening the door to the development of more effective treatments. (2020-01-30)
Potential way to halt blinding macular degeneration identified
It would be the first treatment for dry age-related macular degeneration and could significantly improve treatment for wet AMD. (2020-01-22)
IKBFU scientists developed capsule composition for enzyme against intellectual disability
Phenylpyrovirogradnaya oligophrenia is a disease that results in degradation of the amino acid called phenylalanine. (2020-01-21)
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