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Current Enzyme News and Events

Current Enzyme News and Events, Enzyme News Articles.
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Tiny bubbles in our body could fight cancer better than chemo
Healthy cells in our body release nano-sized bubbles that transfer genetic material such as DNA and RNA to other cells. (2019-09-13)
Some cancer drugs in clinical trials don't work by hitting their targets
Multiple cancer drug candidates in clinical trials kill tumor cells through off-target effects instead of by interacting with their intended molecular targets, according to a new study. (2019-09-11)
University of Minnesota research discovers inhibitor to reverse toxic DUX4 effects
New University of Minnesota Medical School research identifies an inhibitor that protects cells from toxic effects associated with facioscapulohumeral muscular dystrophy in cells and mice. (2019-09-11)
Compound offers prospects for preventing acute kidney failure
Russian researchers from the Moscow Institute of Physics and Technology, the Institute of Cell Biophysics, and elsewhere have shown an antioxidant compound known as peroxiredoxin to be effective in treating kidney injury in mice. (2019-09-09)
Key enzyme found in plants could guide development of medicines and other products
Researchers from the Salk Institute studying how plants evolved the abilities to make natural chemicals, which they use to adapt to stress, have uncovered how an enzyme called chalcone isomerase evolved to enable plants to make products vital to their own survival. (2019-09-06)
High-end microscopy reveals structure and function of crucial metabolic enzyme
The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. (2019-08-28)
Possible treatment on the horizon for severe dengue disease
New study reveals enzyme plays key role in potentially fatal dengue haemorrhagic fever and shock; suggests clinically approved tryptase inhibitor could be key in future targeted treatment. (2019-08-27)
New approaches to heal injured nerves
Injuries to nerve fibers in the brain, spinal cord, and optic nerves usually result in functional losses as the nerve fibers are unable to regenerate. (2019-08-23)
Structure of protein nano turbine revealed
IST Austria scientists determine the first structure of a cell's rotary engine using state-of-art microscopy. (2019-08-22)
Early life on Earth limited by enzyme
A single enzyme found in early single-cell life forms could explain why oxygen levels in the atmosphere remained low for two billion years during the Proterozoic eon, preventing life colonizing land, suggests a UCL-led study. (2019-08-22)
Parasite needs chemical (lipid/nutrient) in cat intestines for sex
Toxoplasma gondii is a microbial parasite that infect humans and complete its full life cycle only in cats. (2019-08-21)
Scientists uncover mystery of DNA methylation
To a large extent, DNA methylation, which regulates vital cell functions, is still a big mystery to the scientific world. (2019-08-19)
Revolutionizing the CRISPR method
Researchers at ETH Zurich have refined the famous CRISPR-Cas method. (2019-08-14)
Making microbes that transform greenhouse gases
A new technique will help not only reduce greenhouse gas emissions, but the potential to reduce the overall dependence on petroleum. (2019-08-13)
Analysis and detoxification in one step
Many industrial and agriculture processes use chemicals that can be harmful for workers and the ecosystems where they accumulate. (2019-08-08)
A scientific approach to recreate metabolic evolution in plants
The research teams at Chiba University, RIKEN, and Kazusa DNA Research Institute confirmed in a paper published in the Plant Journal on July 31, 2019 that the alkaloids were generated by inserting the lysine/ornithine decarboxylating enzyme gene from Lupinus angustifolius producing lysine-derived alkaloid into Arabidopsis thaliana (A. thaliana). (2019-08-01)
Finding weakness in bacterial protein to fight anti-biotic resistance
Researchers reveal previously undiscovered hot spots on the surface of bacteria's critical enzyme, which could guide novel approaches to antibiotic design. (2019-07-31)
Actively swimming gold nanoparticles
Bacteria can actively move towards a nutrient source -- a phenomenon known as chemotaxis -- and they can move collectively in a process known as swarming. (2019-07-31)
Scientists take step toward more efficient fuel refinement processes
Researchers at the Qingdao Institute of Bioenergy and Bioprocesses Technology (QIBEBT) in China have made headway toward more sustainable and economic fuel production by developing a biochemical approach to allow more control over the conversion of natural gas into potable liquid fuel. (2019-07-31)
First pictures of enzyme that drives new class of antibiotics
Researchers have solved the X-ray crystal structure of the enzyme that makes obafluorin -- a broad spectrum antibiotic agent made by a fluorescent strain of soil bacteria. (2019-07-31)
Compound found in red wine opens door for new treatments for depression, anxiety
A new University at Buffalo-led study has revealed that the plant compound resveratrol, which is found in red wine, displays anti-stress effects by blocking the expression of an enzyme related to the control of stress in the brain. (2019-07-26)
Molecular biophysics -- the ABC of ribosome recycling
Ribosomes, the essential machinery used for protein synthesis is recycled after each one round of translation. (2019-07-25)
Preclinical study of therapeutic strategy for Lafora disease shows promise
A team of scientists have designed and tested in mice a novel and promising therapeutic strategy for treating Lafora Disease (LD), a fatal form of childhood epilepsy. (2019-07-25)
Surprising insight into Legionnaires' disease
In order to control cellular processes and thwart the immune system, the bacterium Legionella pneumophilia, the cause of the notorious Legionnaires' disease, releases hundreds of enzymes. (2019-07-24)
How nature builds hydrogen-producing enzymes
A team from Ruhr-Universit├Ąt Bochum and the University of Oxford has discovered how hydrogen-producing enzymes, called hydrogenases, are activated during their biosynthesis. (2019-07-24)
New discovery points toward possible treatment for diabetic non-healing wounds
A new mouse and human tissues study identifies an enzyme critical for normal wound healing that may open up avenues for treatment. (2019-07-23)
Living components
Programmable structural dynamics successful for first time in self-organizing fiber structures (2019-07-22)
Targeting old bottleneck reveals new anticancer drug strategy
The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. (2019-07-22)
Biochemistry: Versatile recycling in the cell
Ribosomes need regenerating. This process is important for the quality of the proteins produced and thus for the whole cell homeostasis as well as for developmental and biological processes. (2019-07-18)
Unlocking chemo-resistance in cancer
Associate Professor Hamsa Puthalakath's explanation of why some cancers don't respond to treatment with one of the most effective chemotherapy drugs: 5-Fluorouracil (5-FU) has the potential to lead to: a lab test to check for 5-FU resistance, which would reduce unnecessary chemotherapy treatments; a new drug to turn off 5-FU in resistance; and he finds 5-FU resistance is linked to a the protein 'BOK,' the function of which has stumped scientists for decades. (2019-07-15)
How DNA outside cells can be targeted to prevent the spread of cancer
Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes. (2019-07-11)
Enzyme responsible for dangerous properties of brain tumor stem cells
The relapse of brain tumors after therapy is driven by cancer stem cells that were not affected by the treatment. (2019-07-11)
UC San Diego cancer scientists identify new drug target for multiple tumor types
A dysfunctional enzyme involved in building cancer cell membranes helps fuel tumor growth; when it's disabled or depleted in mouse models, tumors shrank significantly. (2019-07-11)
Clemson researchers tie metabolic enzyme to obesity and fatty liver disease
Researchers from Clemson University's Environmental Toxicology Program have published research connecting an enzyme associated with detoxification to obesity and fatty liver disease, especially in males. (2019-07-11)
Deep learning-powered 'DeepEC' helps accurately understand enzyme functions
A deep learning-powered computational framework, 'DeepEC,' will allow the high-quality and high-throughput prediction of enzyme commission numbers, which is essential for the accurate understanding of enzyme functions. (2019-07-09)
UBC scientists capture images of gene-editing enzymes in action
For the first time, scientists have captured high-resolution, three-dimensional images of an enzyme in the process of precisely cutting DNA strands. (2019-07-08)
First hi-res images of active CRISPR enzyme will help improve genome editing
For the first time, scientists grappling with how to improve the efficiency of CRISPR technology -- a gene-editing platform that uses an enzyme called Cas9 to precisely cut and edit specific sequences of DNA within a live cell -- have captured atomic-level, three-dimensional images of the enzyme before and after cutting the DNA. (2019-07-08)
Cascade exacerbates storage diseases
In rare, hereditary storage diseases such as Sandhoff's disease or Tay-Sachs syndrome, the metabolic waste from accumulating gangliosides cannot be properly disposed of in the nerve cells because important enzymes are missing. (2019-06-26)
New target for drug intervention in Alzheimer's disease identified
Scientists at UAB have identified an enzyme in the brain, LIMK1, that may be an intriguing target for interventions against Alzheimer's disease and other dementias. (2019-06-25)
Hydrogel offers double punch against orthopedic bone infections
Surgery prompted by automobile accidents, combat wounds, cancer treatment and other conditions can lead to bone infections that are difficult to treat and can delay healing until they are resolved. (2019-06-24)
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