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Current Gene therapy News and Events

Current Gene therapy News and Events, Gene therapy News Articles.
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Adolescent THC exposure alters neurons/gene networks associated with psychosis risk
Adolescent THC exposure reduces the branching of prefrontal cortical neurons and the number of spines, which are critical for cellular communication. (2018-10-17)
Machine-learning driven findings uncover new cellular players in tumor microenvironment
New findings presented today by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients -- those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy. (2018-10-16)
This RNA-based technique could make gene therapy more effective
MIT biological engineers have devised a way to regulate the expression of messenger RNA once it gets into cells, giving them more precise control over gene therapy treatments for cancer and other diseases. (2018-10-16)
Unravelling the genetics of fungal fratricide
Selfish genes are genes that are passed on to the next generation but confer no advantage on the individual as a whole, and may sometimes be harmful. (2018-10-15)
A pheromone-sensing gene that predates land-dwelling vertebrates
Scientists at Tokyo Tech have discovered a gene that appears to play a vital role in pheromone sensing. (2018-10-09)
Mayo clinic researchers question benefits of long term oxygen therapy in COPD
Long-term oxygen therapy does not decrease the risk for hospitalizations or increase life expectancy for many patients with mild to moderate COPD, but may lower their quality of life, according to Mayo Clinic researchers published in The Journal of the American Osteopathic Association. (2018-10-08)
Gene which decreases risk of social network-related stress, increases finance-related stress risk
Researchers have discovered that the same gene which increases your risk of depression following financial stress as you grow older also reduces your chance of depression associated with friendship and relationships stresses when young- your social network. (2018-10-06)
Study examines care for knee replacement patients at physical therapy facilities
In an analysis of 112 records from 30 physical therapy (PT) sites regarding care for patients who had undergone total knee replacement (TKR) surgery, investigators found that the content and amount of specific exercises varied widely. (2018-10-03)
Reducing mutant Huntington disease protein can restore cognitive function in mice
New research from the University of British Columbia suggests that reducing mutated Huntington disease protein in the brain can restore cognitive and psychiatric impairments in mice. (2018-10-03)
Hopkins researchers use endoscope to deliver gene therapy in animal study
Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. (2018-10-02)
A crucial gene controls stem juiciness in sorghum and beyond
Sorghum, the fifth most popular crop worldwide, is used to create many products in the United States and is widely consumed by people in developing countries. (2018-10-02)
Mayo researchers develop new genetics-based prognostic tool for myelodysplastic syndrome
Researchers at Mayo Clinic have developed a new genetics-based prognostic tool for myelodysplastic syndrome. (2018-10-01)
Early Parkinson's patients waiting too long to seek medical evaluation
Too many early Parkinson's disease (PD) patients are treating symptoms before they appear, shrinking the pool of candidates for clinical trials and limiting the chances for a cure. (2018-09-28)
A mechanism of color pattern formation in ladybird beetles
Many ladybirds have attractive color patterns consisting of black and red. (2018-09-26)
Cancer cells evade immunotherapy by hiding telltale marker, suggesting how to stop relapse
Harnessing the immune system to treat cancer shows great promise in some patients, but for many, the response does not last long-term. (2018-09-24)
Mitochondrial diseases could be treated with gene therapy, study suggests
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases: serious and often fatal conditions which affect 1 in 5,000 people. (2018-09-24)
Mosquitoes that can carry malaria eliminated in lab experiments
Researchers have eliminated caged mosquitoes using 'gene drive' technology to spread a genetic modification that blocks female reproduction. (2018-09-24)
Proof-of-concept HIV immunotherapy study passes Phase 1 safety trial
Preliminary results from a phase I clinical trial have demonstrated the safety and tolerability of a cell therapy involving the ex vivo expansion of T cells and their subsequent infusion into HIV-infected individuals previously treated with antiretroviral therapy (ART). (2018-09-21)
Analysis of sea squirt embryo reveals key molecules in dopaminergic neuron differentiation
Researchers at University of Tsukuba used a novel approach for analyzing the central nervous system of a proto-vertebrate to identify a regulatory cocktail that induces the creation of dopaminergic neurons/coronet cells, a primitive version of the hypothalamus. (2018-09-20)
Study: Immediate compression could help prevent complications after deep-vein thrombosis
People with deep-vein thrombosis (DVT) can substantially cut their risk of potentially debilitating complications by starting adequate compression therapy in the first 24 hours of DVT therapy (known as the acute phase of treatment), suggests a study published today in the journal Blood. (2018-09-20)
Black women more likely to skip crucial breast cancer treatments
A new study in the Journal of the National Cancer Institute finds that black women are more likely to skip hormone therapy treatments, also known as endocrine therapy, for breast cancer. (2018-09-20)
Co-evolution between a 'parasite gene' and its host
A Danish research team has delineated a complex symbiosis between a 'parasitic' noncoding RNA gene and its protein coding 'host' gene in human cells. (2018-09-19)
Is the end of the recombinant DNA Advisory Committee (RAC) a good thing?
Recently, the U.S. National Institutes of Health (NIH) and Food and Drug Administration (FDA) called for the eliminating involvement of the Recombinant DNA Advisory Committee (RAC) in human gene therapy experiments, marking the end of an era of federal government oversight. (2018-09-19)
Counting (on) sheep? Promising gene therapy for visually impaired sheep now safe for human trials
A promising gene therapy for visually impaired sheep is now safe for human trials. (2018-09-17)
Gene therapy via skin protects mice from lethal cocaine doses
A study in Nature Biomedical Engineering shows that skin stem cells, modified via CRISPR and transplanted back to donor mice, can protect addicted mice from cocaine-seeking and overdose. (2018-09-17)
Testosterone replacement therapy may slow the progression of COPD
GALVESTON, Texas -- Researchers from The University of Texas Medical Branch at Galveston found that testosterone replacement therapy may slow disease progression of chronic obstructive pulmonary disease. (2018-09-13)
Aging may be as old as life itself
Aging has had a bad rap since it has long been considered a consequence of biology's concentrated effort on enhancing survival through reproductivity. (2018-09-12)
Antioxidant defender protects against osteoarthritis
A protein involved in multiple cellular processes called ANP32A protects cartilage in the joints against degradation by damaging oxidation, preventing the development and progression of osteoarthritis, according to a new study by Frederique Cornelis and colleagues. (2018-09-12)
VTCRI research team identifies a potential strategy in fight against brain cancer
Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body's circadian rhythms is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma. (2018-09-11)
Drug for pancreatic cancer developed by college of pharmacy researchers
University of Houston researchers have developed a new medicine that can inhibit two of the major pathways of pancreatic cancer. (2018-09-11)
Modern antiplatelet therapy: When is clopidogrel the right choice?
In the current issue of Cardiovascular Innovations and Applications (Volume3, Number 2, 2018, pp. (2018-09-10)
Electron microscopy provides new view of tiny virus with therapeutic potential
Researchers from the Salk Institute and the University of Florida are reporting how they used cryo-EM to show the structure of a version of a virus called an AAV2, advancing the technique's capabilities and the virus' potential as a delivery vehicle for gene therapies. (2018-09-07)
New study on obesity: We inherit the dangerous fat from Dad -- and the good fat from Mom
Brown fat cells burn off a lot of calories, whereas an excess of white fat cells make us overweight and ill. (2018-09-06)
Driver gene heterogeneity is minimal among untreated metastases
The growth of different metastatic lesions within an individual cancer patient is driven by the same genetic mutations, a new study reports. (2018-09-06)
Study provides 10-year risk estimates for dementia, which may help with prevention in high-risk individuals who potentially could benefit from early targeted prevention
A Danish study provides 10-year absolute risk estimates for dementia specific to age, sex and common variation in the APOE gene, which may help identify high-risk individuals who potentially could benefit from early targeted prevention. (2018-09-04)
UT study suggests earlier diagnosis, potential therapy for Huntington's disease
A new study published in the Proceedings of the National Academy of Sciences (PNAS) suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling the disease. (2018-09-04)
Hormone therapy can make prostate cancer worse, study finds
Scientists at Cedars-Sinai have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. (2018-09-04)
Stanford scientists engineer way to prevent immune response to gene therapy in mice
Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient's immune system is encountering for the first time. (2018-09-03)
Overcoming resistance
In a recent paper published in the journal Clinical Cancer Research (CCR), Carmelo Nucera, M.D., Ph.D., primary investigator in the thyroid cancer research program in the Division of Experimental Pathology in BIDMC's Department of Pathology, and colleagues investigated the role of pericytes as part of the tumor microenvironment in the subset of papillary thyroid cancers modulated by a mutation of the BRAF cancer-promoting gene. (2018-08-31)
New genetic marker could help diagnose aggressive prostate cancer
Scientists have discovered a link between certain genetic mutations, the aggressiveness of prostate cancer, risk of developing the disease and poorer survival rates of patients. (2018-08-30)
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