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Current Gene therapy News and Events

Current Gene therapy News and Events, Gene therapy News Articles.
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Sclerosing agent delivery improvements to protect against malignant pleural effusion
Preclinical trials were held on mice. Senior Research Associate Alexander Deneka (Laboratory of Molecular and Biochemical Bases of Pathogenesis and Therapy of Cancer Diseases, Kazan Federal University) explains that the method in question was first proposed by British scientists; they proved that liquid can be drained from a pleural cavity with the help of a talcum powder solution. (2019-07-25)
Brains work in sync during music therapy -- study
For the first time researchers have been able to demonstrate that the brains of a patient and therapist become synchronised during a music therapy session, a breakthrough that could improve future interactions between patients and therapists. (2019-07-25)
Genetic screen identifies genes that protect cells from Zika virus
A new Tel Aviv University study uses a genetic screen to identify genes that protect cells from Zika viral infection. (2019-07-25)
Newly identified rice gene confers multiple-herbicide resistance
A rice gene that renders the crop resistant to several widely used beta-triketone herbicides has been identified, researchers report, revealing the genetic cause of herbicide susceptibility that has been identified in some important rice varieties. (2019-07-25)
New method enables more extensive preclinical testing of heart drugs and therapies
A new biomimetic culture system mimics the environment of a living organ through continuous electrical stimulation and oxygenation, maintaining viability and functionality of heart slices for six days. (2019-07-25)
Targeted therapy erdafitinib effective for patients with advanced bladder cancer and specific gene mutations
A Phase II clinical trial led by MD Anderson found that treatment with the FGFR inhibitor erdafitinib was effective in 40% of patients with metastatic bladder cancers marked by FGFR3 mutations. (2019-07-24)
Scientists identify new genetic interactions that may impact cancer outcomes
In a new study, scientists at the University of Maryland and the National Cancer Institute identified 12 distinct types of gene-pair interactions in which varying levels of expression in the two genes correlated with cancer patient survival. (2019-07-23)
Zhang group identifies gene that may make TNBC cells vulnerable to existing
A new study by University of Notre Dame researcher Siyuan Zhang and collaborators, published in Nature Communications, shows that an existing, FDA-approved drug that treats other types of breast cancer may work for TNBC. (2019-07-23)
Parasitic plants use stolen genes to make them better parasites
Some parasitic plants steal genetic material from their host plants and use the stolen genes to more effectively siphon off the host's nutrients. (2019-07-22)
NIH publishes largest genomic study on type 2 diabetes in sub-Saharan African populations
Researchers at NHGRI have performed the largest GWAS study on type 2 diabetes in the sub-Saharan African populations, revealing an association between the disease and previously unlinked ZRANB3 gene. (2019-07-19)
Identification of autophagy gene regulation mechanism related to dementia and Lou Gehrig's disease
An international Research Team led by Dr. Jeong Yoon-ha at Korea Brain Research Institute has published the results of its research in 'Autophagy'. (2019-07-18)
How sex affects gene expression in mammals
Researchers report the discovery of genome-wide variations in gene expression between mammalian females and males and offer new insights into the molecular origins and evolution of sexual dimorphism in mammal species, according to a new study. (2019-07-18)
Researchers confirm the validity of xenographic models for studies of methylation
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify methylation patterns associated with different subtypes of breast cancer, and a subclassification of the group of ''triple negatives'', a breast cancer type typically associated with poor prognosis. (2019-07-18)
Proposed gene therapy for a heart arrhythmia, based on models made from patient cells
Researchers at Boston Children's Hospital report creating the first human tissue model of an inherited heart arrhythmia, replicating two patients' abnormal heart rhythms in a dish, and then suppressing the arrhythmia with gene therapy in a mouse model. (2019-07-17)
New insight into microRNA function can give gene therapy a boost
Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei. (2019-07-17)
Study: First clinical proof that genotypes determine if Alzheimer's drugs will work
University at Buffalo researchers have determined that a human gene present in 75% of the population is a key reason why a class of drugs for Alzheimer's disease seemed promising in animal studies only to fail in human studies. (2019-07-17)
HIV vaccine nears clinical trial following new findings
A promising vaccine that clears an HIV-like virus from monkeys is closer to human testing after a new, weakened version of the vaccine has been shown to provide similar protection as its original version. (2019-07-17)
Does rearranging chromosomes affect their function?
Molecular biologists long thought that domains in the genome's 3D organization control how genes are expressed. (2019-07-15)
New gene linked to healthy ageing in worms
Damage to gene causes impaired movement in adult worms. (2019-07-12)
Successful T cell engineering with gene scissors
The idea of genetically modifying a patient's own immune cells and deploying them against infections and tumors has been around since the 1980s. (2019-07-11)
Enzyme responsible for dangerous properties of brain tumor stem cells
The relapse of brain tumors after therapy is driven by cancer stem cells that were not affected by the treatment. (2019-07-11)
Metabolic reprogramming of branched-chain amino acid facilitates drug resistance in lung cancer
Research teams led by Dr. Ji Hongbin at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences, Dr. (2019-07-09)
Light therapy could replace opioids as main treatment for cancer treatment side effect
A worldwide coalition of researchers and clinicians has agreed that light therapy is among the most effective interventions for the prevention of oral mucositis, painful ulcers in the mouth resulting from cancer therapy. (2019-07-09)
Body plan evolution not as simple as once believed
Hox gene do not work alone to determine the layout of vertebrae, limbs and other body parts. (2019-07-09)
From centenarians' genetic code, a potential new therapy against cardiovascular diseases
Some people live much longer than average, partly thanks to their DNA. (2019-07-09)
Cancer genes and the tumor milieu
In a recent study published in Cancer Research, researchers demonstrate the role of an oncogene in altering the immediate environment of tumors. (2019-07-08)
Discovery reveals prolific ability of Schwann cells to generate myelin
Scientists have discovered that a special type of cell is much more prolific in generating a protective sheath covering nerve fibers than previously believed. (2019-07-05)
Discovery of mechanism behind precision cancer drug opens door for more targeted treatment
New research that uncovers the mechanism behind the newest generation of cancer drugs is opening the door for better targeted therapy. (2019-07-04)
Saving Beethoven
An optimized version of the CRISPR-Cas9 gene-editing system prevents hearing loss with no detectable off-target effects in so-called Beethoven mice, which carry a mutation that causes profound hearing loss in humans and mice alike. (2019-07-03)
Androgen deprivation therapy associated with risk of alzheimer, dementia diagnoses in older men with prostate cancer
Data for 154,089 older men diagnosed with prostate cancer were used to analyze the association between androgen deprivation therapy, a hormone-suppressing therapy used to treat prostate cancer, and subsequent diagnosis of Alzheimer disease or dementia. (2019-07-03)
Scissors get stuck -- another way bacteria use CRISPR/Cas9
Before humans repurposed it as a gene editing tool, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages. (2019-07-01)
Protein linked to aggressive skin cancer
Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common forms of cancer. (2019-06-28)
A snapshot in time: Study captures fleeting cell differences that can alter disease risk
In cinema and science fiction, one small change in the past can have major, sometimes life-changing effects in the future. (2019-06-27)
The two faces of the Jekyll gene
Genes which are specific to a species or group of species can reflect important genetic changes within lineages. (2019-06-26)
Scientists developing way to help premature babies breathe easier
Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia (BPD), which in the most severe cases can lead to lifelong breathing problems and even death. (2019-06-26)
Genetically modified virus combats prostate cancer
In a study with mice, a gene therapy developed in Brazil kills cancer cells and avoids adverse side effects when combined with chemotherapy. (2019-06-26)
New osteoporosis therapy's dual effects on bone tissue
Sclerostin is a protein produced by osteocytes in the bone that inhibits bone formation. (2019-06-25)
First in vivo proof-of-concept in Steinert's myotonic dystrophy
Ana Buj Bello's team, a researcher in an Inserm unit at Genethon, the AFM-Telethon laboratory, has made the proof-of-concept of a CRISPR-Cas9 approach in a mouse model of Steinert's myotonic dystrophy, the most common neuromuscular disease in adults. (2019-06-25)
De-escalating breast cancer therapy; can some patients be spared chemotherapy?
Researchers develop molecular testing to distinguish patients who may need less from those who may need more therapy for HER2 positive breast cancer. (2019-06-25)
Study investigates role of family doctors in advanced therapies
A group of researchers at the University of Granada has conducted a study into the knowledge and attitudes of Family Medicine residents, in relation to the so-called 'advanced therapies'. (2019-06-24)
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