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Current Genome News and Events

Current Genome News and Events, Genome News Articles.
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Research implicates causative genes in osteoporosis, suggesting new targets for future therapy
Scientists have harnessed powerful data analysis tools and three-dimensional studies of genomic geography to implicate new risk genes for osteoporosis, the chronic bone-weakening condition that affects millions of people. (2019-03-21)
Pathogenic, drug-resistant bacteria found in wastewater treatment plants
Infections caused by drug-resistant bacteria are a global public health threat causing serious illness and even death. (2019-03-21)
How hot spots of genetic variation evolved in human DNA
New research investigates hot spots of genetic variation within the human genome, examining the sections of our DNA that are most likely to differ significantly from one person to another. (2019-03-19)
Rabbits like to eat plants with lots of DNA
Rabbits prefer to eat plants with plenty of DNA, according to a new study by Queen Mary University of London and Royal Botanic Gardens, Kew. (2019-03-19)
Enzyme USP15 may have potential role in future treatment of various cancers
A team at the George Washington University Cancer Center found that the deubiquitinating enzyme USP15 is a potential biomarker for treatments of pancreatic cancer, as well as ovarian and breast cancers. (2019-03-15)
Scientists crack genome of superfood seaweed, ito-mozuku
For the first time, researchers unveil the genome of ito-mozuku (Nemacystus decipiens), the popular Japanese brown seaweed, providing data that could help farmers better grow the health food. (2019-03-14)
The genetics of regeneration
Led by Assistant Professor of Organismic and Evolutionary Biology Mansi Srivastava, a team of researchers is shedding new light on how animals perform whole-body regeneration, and uncovered a number of DNA switches that appear to control genes used in the process. (2019-03-14)
Discovery upturns understanding of how some viruses multiply
Scientists have shown that different segments of a virus genome can exist in distinct cells but work together to cause an infection. (2019-03-12)
Genes that evolve from scratch expand protein diversity
A new study published in Nature Ecology and Evolution led by scientists from the University of Chicago challenges one of the classic assumptions about how new proteins evolve. (2019-03-11)
Illuminating the genome
Development of a new molecular visualisation method, RNA-guided endonuclease -- in situ labelling (RGEN-ISL) for the CRISPR/Cas9-mediated labelling of genomic sequences in nuclei and chromosomes. (2019-03-08)
Could genetic breakthrough finally help take the sting out of mouth ulcers?
A large breakthrough has been made in the genetic understanding of mouth ulcers which could provide potential for a new drug to prevent or heal the painful lesions. (2019-03-05)
A quick path to antimalarial resistance
Resistance to antimalarial drugs is thought to result mainly from changes in the parasite's genome. (2019-03-04)
How new species arise in the sea
How can a species split into several new species if they still live close to each other and are able to interbreed? (2019-03-04)
Checking DNA base editor's mistakes and tricks to reduce them
IBS scientists have identified the mistake-rate of DNA editing tools, based on CRISPR and known as adenine base editors. (2019-03-04)
Genomic testing of a single patient reveals a gene commonly mutated in pediatric melanoma
Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma. (2019-03-04)
Researchers reveal unexpected genome-wide off-target mutations caused by cytosine base editing
A research team led by Professor GAO Caixia of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences performed a comprehensive investigation of the off-target mutations of BE3, HF1-BE3 and ABE using whole genome sequencing (WGS) in rice, an important crop species. (2019-02-28)
China-led research collaboration develops new way to test gene-editing safety
Chinese and international scientists have developed a new technique to evaluate the safety of genome-editing tools -- a method that could become the industry standard. (2019-02-28)
Scientists lay foundation for single-cell level understanding of DNA replication
A research team established a novel method to scrutinize DNA replication in individual cells. (2019-02-25)
Cool adaptations to the cold
Icefish live in an environment that should be deadly for them. (2019-02-25)
Uncovering the origins of cultivated strawberries
In a new study published in Nature Genetics, researchers now unveil how the strawberry became an octoploid, as well as the genetics that determine important fruit quality traits. (2019-02-25)
Breeding a better strawberry
An international team of scientists led by the University of California, Davis, and Michigan State University have sequenced and analyzed the genome of the cultivated strawberry, which will provide a genetic roadmap to help more precisely select desired traits. (2019-02-25)
Common virus is 'less prone to mutation' giving hope for vaccine development
One of the commonest causes of congenital disability, the Human Cytomegalovirus (HCMV), is less prone to mutation than previously thought, a finding which could help develop a successful vaccine, UCL researchers have found. (2019-02-25)
Revealing the role of the mysterious small proteins
CRG investigators develop a technique to identify and classify proteins with less than 100 amino acids. (2019-02-22)
Scientists sharpen their molecular scissors and expand the gene editing toolbox
Wake Forest Institute for Regenerative Medicine scientists have figured out a better way to deliver a DNA editing tool to shorten the presence of the editor proteins in the cells in what they describe as a 'hit and run' approach. (2019-02-22)
New strategy improves efficiency of CRISPR-Cas9 genome editing
The efficiency of CRISPR genome editing tools targeted to the site of interest by Cas9 nucleases varies considerably and a new CMP-fusion strategy, called CRISPR-chrom, enhances the activity up to several-fold. (2019-02-21)
Researchers find genetic clues to high rates of asthma in those of African ancestry
In the largest study of its kind, researchers at the University of Colorado Anschutz Medical Campus have found new clues into the parts of the human genome associated with the higher rates of asthma in those of African ancestry. (2019-02-20)
New blood test may map fetal genome for countless mutations
Tel Aviv University researchers have developed a new blood test for genetic disorders that may allow parents to learn about the health of their baby as early as 11 weeks into pregnancy. (2019-02-20)
New study shows hidden genes may underlie autism severity
Scientists at the University of Colorado Anschutz Medical Campus have implicated a largely hidden part of the human genome in the severity of autism symptoms, a discovery that could lead to new insights into the disorder and eventually to clinical therapies for the condition. (2019-02-15)
Uncovering a 'smoking gun' of biological aging clocks
A newly discovered ribosomal DNA (rDNA) clock can be used to accurately determine an individual's chronological and biological age, according to research led by Harvard T.H. (2019-02-14)
More scrutiny needed for less-deadly foodborne bacteria
Employing advanced genetic-tracing techniques and sharing the data produced in real time could limit the spread of bacteria -- Bacillus cereus -- which cause foodborne illness, according to researchers who implemented whole-genome sequencing of a pathogen-outbreak investigation. (2019-02-13)
Genome scientists develop novel approaches to studying widespread form of malaria
Scientists at the Institute of Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately eradicate Plasmodium vivax, the most widespread form of malaria. (2019-02-08)
The novel method Nested CRISPR enables efficient genome editing using long DNA fragments
The group of Dr. CerĂ³n at IDIBELL used the model organism Caenorhabditis elegans to optimize the technique, leading to the development of the method called Nested CRISPR. (2019-02-07)
Male Y chromosomes not 'genetic wastelands'
Researchers from the University of Rochester have found a way to sequence a large portion of the Y chromosome in the fruit fly Drosophila melanogaster--the most that the Y chromosome has been assembled in fruit flies. (2019-02-06)
Genome structure of malaria parasites linked to virulence
An international research team led by scientists at the University of California, Riverside, and the La Jolla Institute for Immunology has found that malaria parasite genomes are shaped by parasite-specific gene families, and that this genome organization strongly correlates with the parasite's virulence. (2019-02-04)
Over 800 new genome regions possibly relevant to human evolution identified
Researchers at the UAB have found genetic evidence of adaptations in 2,859 regions of the human genome, including some well-known examples such as those responsible for milk tolerance or high-altitude adaptation. (2019-02-04)
How transcription factors explore the genome
EPFL scientists have discovered how proteins that regulate gene transcription can scan and bind the genome efficiently. (2019-01-30)
A small fish provides insight into the genetic basis of evolution
Genetic analysis of sticklebacks shows that isolated populations in similar environments develop in comparable ways. (2019-01-30)
Huge step forward in decoding genomes of small species
For the first time, scientists have read the whole genetic code of one single mosquito. (2019-01-29)
Kick-starting the genome in early development
We can think of the egg and sperm as information capsules with stored instructions for starting a new life, but post fertilisation, what kick starts the interpretation of these instructions? (2019-01-28)
PopPUNK advances speed of bacterial pathogen surveillance
In a study published today in Genome Research, researchers developed PopPUNK (Population Partitioning Using Nucleotide K-mers), a computational tool for analyzing tens of thousands of bacterial genomes in a single run, up to 200-fold faster than previous methods. (2019-01-24)
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