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Current Genome News and Events

Current Genome News and Events, Genome News Articles.
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Not so selfish after all--Key role of transposable elements in mammalian evolution
A scientist at Tokyo Institute of Technology (Tokyo Tech) has revealed a key role for 'selfish' transposable elements in the evolution of the mammary gland, a defining feature of all mammals. (2019-11-20)
Breakthrough in malaria research
An international scientific consortium led by the cell biologists Volker Heussler from the University of Bern and Oliver Billker from the Umeå University in Sweden has for the first time systematically investigated the genome of the malaria parasite Plasmodium throughout its life cycle in a large-scale experiment. (2019-11-14)
Turning 'junk' DNA into gold
Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer. (2019-11-14)
How the cellular recycling system is put on hold while cells divide
Research involving several teams at the Babraham Institute, Cambridge, UK, has shown that cellular recycling (autophagy) is repressed during the process of cell division, and how repression of autophagy during mitosis utilises a different master regulator. (2019-11-13)
Yale study finds 'hyperhotspots' that could predict skin cancer risk
New research by Yale University scientists reports the discovery of 'hyperhotspots' in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome average. (2019-11-13)
Team plucks needle from genomic haystack, finding essential transcription factor binding sites
Using CRISPR/Cas9 knockout screens, a multi-institutional research team systematically interrogated the essentiality of more than 10,000 forkhead box protein A1 (FOXA1) and CTCF binding sites in breast and prostate cancer cells, finding that essential FOXA1 binding sites act as enhancers to orchestrate the expression of nearby essential genes. (2019-11-11)
A new CRISPR-Cas9 protein to increase precision of gene editing
A team of researchers from City University of Hong Kong (CityU) and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in the genome editing process. (2019-11-06)
Mutations linked to expression of genes associated with complex traits
Hard-to-study mutations in the human genome, called short tandem repeats, known as STRs or microsatellites, are implicated in the expression of genes associated with complex traits including schizophrenia, inflammatory bowel disease and even height and intelligence. (2019-11-05)
EMBL spins the Sleeping Beauty transposase
EMBL scientists have developed a new variant of the Sleeping Beauty transposase. (2019-11-04)
DNA exchange among species is major contributor to diversity in Heliconius butterflies
Exchange of genetic material among species played a major role in the wide diversity of Heliconius butterflies, according to a new study, results of which inform a centuries-long debate about the value of hybridization to species evolution. (2019-10-31)
U. Iowa team is developing new delivery tools for gene editing
Scientists led by University of Iowa researcher Paul McCray, Jr., MD, are using simple peptides to deliver gene-editing tools into notoriously hard-to-access lung and airway cells with the goal of creating new treatments for people with diseases like cystic fibrosis, COPD, and asthma. (2019-10-31)
Argonaute proteins help fine-tune gene expression
A protein, with a name reminiscent of legendary Greek sailors, has an unexpected role inside the human nucleus. (2019-10-28)
Study provides framework for 1 billion years of green plant evolution
Gene sequences for more than 1,100 plant species have been released by an international consortium of nearly 200 plant scientists, the culmination of a nine-year research project. (2019-10-23)
Scientists pioneer new way of finding cancer-causing germs
University of East Anglia scientists are pioneering a new way of finding cancer-causing germs. (2019-10-21)
New diagnostic method finds aggressive tumors
Researchers at Karolinska Institutet in Sweden have developed a new cheap method that can identify highly heterogeneous tumors that tend to be very aggressive, and therefore need to be treated more aggressively. (2019-10-18)
New human reference genome resources help capture global genetic diversity
Scientists have assembled a set of genetic sequences that enable the reference genome to better reflect global genetic diversity. (2019-10-16)
'The ethics of human genome editing' special issue published in The CRISPR Journal
The Ethics of Human Genome Editing is the subject of intensive discussion and debate in a special issue of The CRISPR Journal, a new peer-reviewed journal from Mary Ann Liebert, Inc., publishers. (2019-10-16)
DNA fracturing rewires gene control in cancer
A multi-institutional team led by researchers at Baylor College of Medicine has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers. (2019-10-15)
NYU Abu Dhabi researchers release a new genome sequence of the date palm
Researchers at NYU Abu Dhabi's Center for Genomics and Systems Biology (NYUAD CGSB) and the UAEU Khalifa Center for Genetic Engineering and Biotechnology (KCGEB), working with other institutions, have developed an improved assembly of the genome for the date palm using long-read sequencing technology. (2019-10-15)
Sperm and egg cell 'immune response' protects koala DNA
Discovery of a type of immunity that protects koalas' DNA from viruses has importance for the survival of koalas and our fundamental understanding of evolution. (2019-10-14)
Koala epidemic provides lesson in how DNA protects itself from viruses
In animals, infections are fought by the immune system. Studies on an unusual virus infecting wild koalas, by a team of researchers from the University of Massachusetts Medical School and the University of Queensland, reveal a new form of 'genome immunity.' The study appears Oct. (2019-10-10)
New study reveals an innate genome immune response to retroviruses in koalas
A new study from researchers at UMass Medical School and the University of Queensland in Australia identifies a never-before-seen type of immune response in an animal already known for being unique: the koala bear. (2019-10-10)
Fruit flies help in the development of personalized medicine
It is common knowledge that there is a connection between our genes and the risk of developing certain diseases. (2019-10-09)
CRISPR-BEST prevents genome instability
Scientists from The Novo Nordisk Foundation Center for Biosustainability has developed CRISPR-BEST, a new genome editing tool for actinomycetes. (2019-10-09)
New study challenges our understanding of premature ageing
Disturbances in the function of mitochondrial DNA can accelerate the ageing process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism. (2019-10-08)
Genome-edited bull passes on hornless trait to calves
For the past two years, researchers at the University of California, Davis, have been studying six offspring of a dairy bull, genome-edited to prevent it from growing horns. (2019-10-07)
Histone modifications are the influencers of zygotic genome awakening
Scientists at Tokyo Institute of Technology (Tokyo Tech) observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to 'histone H3', one of the proteins around which DNA is bound, play an important role in 'zygotic genome activation' or transition of control of zebrafish embryonic development from maternal material to the zygote. (2019-10-07)
Complete genome of devastating soybean pathogen assembled
An international research collaboration has successfully assembled the complete genome sequence of the pathogen that causes the devastating disease Asian soybean rust. (2019-10-03)
Study presents first genome sequence of Florida panther
Once dwindling in numbers and suffering from the hereditary effects of inbreeding, the Florida panther is on the rebound, and researchers now have more genetic data to prove it. (2019-10-03)
Why multipartite viruses infect plants rather than animals
Being in between living and non-living, viruses are, in general, strange. (2019-10-01)
Whole genome sequencing could enable personalised cancer treatment, study suggests
Whole genome sequencing of tumour cells could help predict the prognosis of a patient's cancer and offer clues to identify the most effective treatment, suggests an international study published today in Nature Medicine. (2019-09-30)
Skin-cells-turned-to-heart-cells help unravel genetic underpinnings of cardiac function
A small genetic study, published September 30, 2019 in Nature Genetics, identified a protein linked to many genetic variants that affect heart function. (2019-09-30)
New CRISPR-Cas9 variant may boost precision in gene editing
Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans. (2019-09-30)
The almond & peach trees genomes shed light on the differences between these close species
An international team led by researchers from CRAG has sequenced the genome of the almond tree and compared it to that of its closest relative, the peach tree. (2019-09-25)
Some high-cholesterol genes differ between countries
Some of the genes that predict the risk of high cholesterol don't apply to people from Uganda the same as they do in European populations, finds a new UCL-led study published in Nature Communications. (2019-09-24)
Improved mapping of Swedish genes
People -- or more specifically just Swedes -- are more like chimpanzees than previously known. (2019-09-24)
Improved mapping of Swedish genes from 1,000 individuals
People -- or more specifically just Swedes -- are more like chimpanzees than previously known. (2019-09-24)
New method provides better understanding of gene 'enhancers' work
Using anew method called Net-CAGE, researchers identified as many as 20,000 new enhancers in humans. (2019-09-24)
New insight as to how cells maintain their identity
In the body's cells, some proteins are of vital importance as to which genes are active or turned off. (2019-09-20)
Why the lettuce mitochondrial genome is like a chopped salad
The genomes of mitochondria are usually depicted as rings or circles. (2019-09-20)
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