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Current Glioblastoma News and Events

Current Glioblastoma News and Events, Glioblastoma News Articles.
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How preserve the properties of polyphenols and flavonoids in oncological treatments?
A new technique preserves the anti-carcinogenic properties of polyphenols and flavonoids in oncological treatments. (2020-05-27)
Treatment shows promise in treating deadly brain cancer
In this study, researchers investigated if specific targeting of CD133+ glioblastoma with cutting-edge immunotherapy drugs could eradicate the most aggressive subpopulation of cells in the tumor. (2020-05-27)
Anti-malarial drug shows promise for brain cancer treatment
Glioblastoma multiforme (GBM) is an aggressive form of cancer in the brain that is typically fatal. (2020-05-26)
Genome-wide pattern found in tumors from brain cancer patients predicts life expectancy
For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma -- the most common and the most aggressive brain cancer -- has been age at diagnosis. (2020-05-15)
University of Minnesota researchers study radiation resistance in brain cancer cells
In a vertical climb to avoid collision with a towering mountain, a plane ejects cargo to gain altitude. (2020-05-14)
Researchers develop 'piggyback' method to improve drug delivery of RNA therapeutics
A group of researchers from University of Toronto Engineering and SickKids Hospital have developed a new way to deliver molecules that target specific genes within cells. (2020-05-01)
Schizophrenia drug combined with radiation shows promise in treating deadly brain tumors
UCLA researchers found adding a drug once commonly used to treat schizophrenia to traditional radiation therapy helped improve overall survival in mice with glioblastoma. (2020-05-01)
CBD shows promise for fighting aggressive brain cancer
Findings from a new study examining human and canine brain cancer cells suggest that cannabidiol, or CBD, could be a useful therapy for a difficult-to-treat brain cancer. (2020-04-27)
Boosting the immune system's appetite for cancer
A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission. (2020-04-23)
Potential therapy for rare neurologic disease
A targeted therapy, currently being studied for treatment of certain cancers including glioblastoma, may also be beneficial in treating other neurologic diseases, a study at the University of Cincinnati shows. (2020-04-06)
Oncotarget Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy
The cover for issue 11 of Oncotarget features Figure 6, 'Effects of AZD8186 in combination with anti-PD1 on syngeneic models,' by Owusu-Brackett, et al. (2020-03-18)
New imaging technique enables the study of 3D printed brain tumors
In research published in Science Advances, Xavier Intes, a professor of biomedical engineering at Rensselaer, joined a multidisciplinary team from Northeastern University and the Icahn School of Medicine at Mount Sinai to demonstrate a methodology that combines the bioprinting and imaging of glioblastoma cells in a cost-effective way that more closely models what happens inside the human body. (2020-03-06)
Engineered bone marrow cells slow growth of prostate and pancreatic cancer cells
In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response. (2020-03-05)
Imaging can guide whether liquid biopsy will benefit individual glioblastoma patients
New research shows brain imaging may be able to predict when a blood test known as a liquid biopsy would or would not produce clinically actionable information, allowing doctors to more efficiently guide patients to the proper next steps in their care. (2020-02-27)
Surveillance after surgery does not improve outcomes for patients with glioblastoma
A retrospective study from the University of Missouri School of Medicine and MU Health Care showed patients who underwent surveillance imaging after surgery for brain tumor resection did not have better outcomes than patients who did not have imaging and returned when they felt symptoms of recurrence. (2020-02-26)
Targeting stromal cells may help overcome treatment resistance in glioblastoma
The deadly brain cancer glioblastoma (GBM) is often resistant to chemotherapy and radiation, but new research shows targeting stromal cells -- the cells that serve as the connective tissue of the organs -- may be an effective way of overcoming that resistance. (2020-02-26)
A potential new weapon against deadly brain and soft tissue cancers
Researchers at the USC Viterbi School of Engineering have designed a new drug cocktail that kills some types of brain and soft tissue cancers by tricking the cancer cells to behave as if they were starving for their favorite food -- glucose. (2020-02-20)
Finding new clues to brain cancer treatment
Researchers at Case Western Reserve University School of Medicine and Cleveland Clinic new discovered a more accurate way to determine the relative life expectancy of glioblastoma victims and identify who could be candidates for experimental clinical drug trials by blending information from Artificial Intelligence (AI)--in this case, computer image analysis of the initial MRI scans taken of brain cancer patients--and genomic research. (2020-02-20)
Scientists find ally in fight against brain tumors: Ebola
Glioblastomas are relentless, hard-to-treat, and often lethal brain tumors. Yale scientists have enlisted a most unlikely ally in efforts to treat this form of cancer -- elements of the Ebola virus. (2020-02-12)
Brain tumor surgery that pushes boundaries boosts patients survival
Survival may more than double for adults with glioblastoma, the most common and deadly type of brain tumor, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor. (2020-02-06)
Cancer mutations occur decades before diagnosis
A large-scale pan-cancer analysis of the evolutionary history of tumours reveals that cancer-causing mutations occur decades before diagnosis. (2020-02-05)
Poliovirus therapy shows potential as cancer vaccine in lab studies
A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine. (2020-01-30)
Buck researchers discover how cellular senescence leads to neurodegeneration
Although a link has been established between chronic inflammation and neurodegenerative diseases, there have been many open questions regarding how cellular senescence, a process whereby cells that stop dividing under stress spew out a mix of inflammatory proteins, affects these pathologies. (2020-01-29)
Stem cells, CRISPR and gene sequencing technology are basis of new brain cancer model
University of California San Diego School of Medicine researchers created a new type of brain cancer model for glioblastoma using stem cells, CRISPR and gene sequencing. (2020-01-28)
Immune system cells contribute to the invading capacity of brain tumours
An article published in Brain Communications, coordinated by Carlos Barcia, researcher at Institut de Neurociències de la UAB, describes how the immune system facilitates the expansion of tumour cells in the brain. (2020-01-23)
Zika virus' key into brain cells ID'd, leveraged to block infection and kill cancer cells
Two different UC San Diego research teams identified the same molecule -- αvβ5 integrin -- as Zika virus' key to brain cell entry. (2020-01-16)
Improved brain chip for precision medicine
The Akay Lab biomedical research team at the University of Houston is reporting an improvement on a microfluidic brain cancer chip previously developed in their lab. (2020-01-16)
Meningeal lymphatic network: A new avenue in the treatment of brain tumors
Glioblastomas are the most common type of brain tumor, and their prognosis is often highly unfavorable. (2020-01-15)
Scientists breach brain barriers to attack tumors
The brain is a sort of fortress, equipped with barriers designed to keep out dangerous pathogens. (2020-01-15)
Brazilian scientists unveil chemotherapy resistance mechanism related to p53 mutation
Brazilian study uncovered an anticancer chemotherapy resistance mechanism related to amyloid aggregation of mutant p53. (2020-01-08)
Brain tumor organoids may be key to time-sensitive treatments for glioblastomas
Lab-grown brain organoids developed from a patient's own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it. (2019-12-26)
Researchers identify immune-suppressing target in glioblastoma
Researchers at The University of Texas MD Anderson Cancer Center have identified a tenacious subset of immune macrophages that thwart treatment of glioblastoma with anti-PD-1 checkpoint blockade, elevating a new potential target for treating the almost uniformly lethal brain tumor. (2019-12-23)
New treatment Strategy may thwart deadly brain tumors
New research reveals a promising strategy that makes glioblastoma susceptible to immune checkpoint inhibitors. (2019-12-23)
Ultrasound blasts potent glioblastoma drug into brain tumor
A potent drug for glioblastoma can't be used in patients. (2019-12-12)
Biomarker may aid in determining treatment for cancer patients
A blood test revealed the presence of a biomarker that may offer insights into the survival rates of glioblastoma patients. (2019-12-09)
New methodology developed at UPV to monitor patients with glioblastoma
The UPV methodology helps medical doctors know the patients' situation with greater precision; it allows them to obtain several vascular biomarkers directly linked to their survival. (2019-12-04)
New treatment for brain tumors uses electrospun fiber
University of Cincinnati professor Andrew Steckl, working with researchers from Johns Hopkins University, developed a new treatment for glioblastoma multiforme, an aggressive form of brain cancer. (2019-12-02)
Exploring drug repurposing to treat glioblastoma
MALT1 blockers have long been in clinical use for the treatment of blood cancers. (2019-11-27)
Non-coding DNA located outside chromosomes may help drive glioblastoma
According to a new Cell study, extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going -- elements that could represent new drug targets for brain tumors and other cancers notoriously difficult to treat. (2019-11-21)
Potential drug targets for glioblastoma identified
Researchers at Karolinska Institutet in Sweden have identified 10 tumour-specific potential drug targets for the brain tumour glioblastoma. (2019-11-05)
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