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Current Hematology News and Events

Current Hematology News and Events, Hematology News Articles.
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For acute myeloid leukemia, genetic testing is often worth the wait
New tailored therapies offer exciting prospects for treating acute myeloid leukemia (AML), but taking advantage of them may require waiting a week or more for genetic testing before starting treatment, posing a dilemma for doctors and patients facing this deadly and often fast-moving disease. (2020-06-04)
Early treatment linked to reduced joint damage in young adults with severe hemophilia A
Children with severe hemophilia A who receive early prophylaxis are less likely to have joint damage in young adulthood than those who begin treatment later, according to a new study in Blood Advances. (2020-06-03)
New MDS subtype proposed based on presence of genetic mutation
In a special report published today in the journal Blood, an international working group of experts in myelodysplastic syndromes (MDS) proposes -- for the first time -- the recognition of a distinct subtype of MDS based on the presence of a nonheritable genetic mutation that causes the disease. (2020-04-29)
Impact of donor lymphocyte infusion and intensified conditioning for relapsed/refractory leukemia
Leukemia relapse is still a major problem that impedes the success of hematopoietic cell transplant (HCT). (2020-04-15)
New prognostic tool helps leukemia patients plan for cancer treatment
A new prognostic tool predicts how long someone diagnosed with chronic lymphocytic leukemia (CLL) will be able to wait before starting cancer treatment. (2020-04-08)
Case study: Treating COVID-19 in a patient with multiple myeloma
A case study of a patient in Wuhan, China, suggests that the immunosuppressant tocilizumab may be an effective COVID-19 treatment for very ill patients who also have multiple myeloma and other blood cancers. (2020-04-03)
The pros and cons of radiotherapy: Will it work for you?
Women undergoing radiotherapy for many cancers are more likely than men to be cured, but the side effects are more brutal, according to one of Australia's most experienced radiation oncology medical physicists. (2020-03-29)
Novel sepsis treatment enhances bacterial capture by neutrophil 'traps'
Researchers at Children's Hospital of Philadelphia (CHOP) have developed a novel treatment for sepsis - one of the leading causes of hospital death - that enhances the body's bacteria-capturing neutrophil extracellular traps (NETs) so that they more effectively capture infectious bacteria, resist degradation, and improve sepsis outcomes and survival. (2020-03-05)
Study finds gender disparities in hematology research success
Hematologists who complete a mentored training program experience greater levels of academic success than those who do not; however, a study published today in Blood Advances suggests a slight discrepancy in success levels between male and female hematologists. (2020-02-25)
New study finds cellular immunotherapy treatment associated with improved quality of life
Adult lymphoma patients whose disease was effectively treated with chimeric antigen receptor T-cell (CAR-T) therapy showed marked improvement on a variety of self-reported quality of life measures, according to a study published today in Blood Advances. (2020-02-19)
City of Hope's Triplex vaccine reduces rate of CMV complications in transplant recipients
Patients who underwent a stem cell transplant and received the Triplex vaccine to prevent a type of herpes virus -- cytomegalovirus (CMV) -- from duplicating out of control were 50% less likely to develop health complications related to the virus than patients who did not take Triplex, according to a City of Hope-led study published today in Annals of Internal Medicine. (2020-02-10)
Single-cell sequencing of CLL therapy: Shared genetic program, patient-specific execution
Researchers at the CeMM Research Center for Molecular Medicine and partners in Budapest have studied the response to targeted leukemia therapy in unprecedented detail, using single-cell sequencing and epigenetic analysis. (2020-01-29)
Hope for patients with a rare genetic condition linked to severe infections
A research team sheds light on the mechanisms underlying chronic granulomatous disease. (2020-01-22)
Partnership with China prompts change in care for high-risk type of leukemia
Findings from a collaborative clinical trial have generated key insights into how targeted therapy should be used to treat leukemia driven by the Philadelphia chromosome. (2020-01-16)
Metabolic syndrome associated with increased risk of blood clot recurrence
People with metabolic syndrome -- a set of conditions including obesity, impaired glucose metabolism, elevated levels of fats and cholesterol in the blood, and high blood pressure - are more likely to experience recurrent blood clots, according to a new study published today in Blood Advances. (2020-01-09)
New study finds blood clots more likely in children who receive PICCs
A new study provides convincing evidence that the use of peripherally inserted central catheters (PICCs) to administer medicine and draw blood in children is associated with a significantly increased risk of blood clots (known as venous thromboembolism or VTE) compared with central venous catheters (CVCs) placed directly into the neck or chest. (2020-01-07)
Researchers identify potential formula for blood cancer vaccine
Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research, in December. (2019-12-19)
Dana-Farber scientists present promising findings in multiple myeloma at ASH Annual Meeting
Results of studies on a novel agent to treat multiple myeloma and a combination therapy aimed at slowing the progression of a precursor myeloma condition are among reports being presented by Dana-Farber Cancer Institute investigators at the ASH Annual Meeting. (2019-12-09)
Treatment with PD-1 prior to stem cell transplant is safe for Hodgkin lymphoma patients
A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma. (2019-12-09)
E1912 follow-up shows ibrutinib effective, well tolerated by majority of CLL patients
The ECOG-ACRIN Cancer Research Group today announced results from extended follow-up of patients in its randomized Phase 3 clinical trial, E1912. (2019-12-07)
Genomic features of AML in patients over age 60 can predict success of stem cell transplant
For older patients with AML, the prospects for success of a stem cell transplant can often be predicted based on the particular set of genetic mutations within the tumor cells, investigators at Dana-Farber Cancer Institute will report at the ASH Annual Meeting. (2019-12-07)
Use of venetoclax in transplant conditioning regimen shows promise in myeloid cancers
For patients with high-risk myeloid cancers undergoing a donor stem cell transplant, adding the targeted drug venetoclax to a reduced-intensity drug regimen prior to transplant is safe and does not impair the ability of the donor cells to take root in recipients' bodies. (2019-12-07)
Light-to-moderate exercise may bring benefits for sickle cell disease
While exercise offers benefits for a wide range of health conditions, it has historically been considered too dangerous for people living with sickle cell disease (SCD). (2019-11-19)
Study: Multidisciplinary transplantation evaluation shows promise for older adults
Older adults with blood cancers can benefit from a team-based, holistic evaluation before undergoing transplantation, according to a new study published today in Blood Advances. (2019-11-14)
Survey suggests mentorship in medical school is vital to future of hematology
A survey of US hematology-oncology fellows suggests medical school plays an important role in shaping their interest in pursuing careers in hematology, particularly when students are exposed to hematology and oncology as part of core clerkships in internal medicine and pediatrics. (2019-10-31)
Novel approach identifies factors linked to poor treatment outcomes in ALL
Profiling the metabolites produced in the bone marrow at the time of diagnosis enabled researchers to identify high-risk acute lymphoblastic leukemia (ALL) patients. (2019-10-24)
Scientists discover reasons why targeted immuno-oncology drugs sometimes fail
Researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. (2019-10-23)
Study finds racial disparities in treatment of multiple myeloma patients
Among patients with multiple myeloma, African-Americans and Hispanics start treatment with a novel therapy significantly later than white patients, according to a new study published today in Blood Advances. (2019-10-17)
Study: Ibrutinib linked to high blood pressure and other heart problems
Over half of people prescribed the targeted blood cancer-fighting drug ibrutinib developed new or worsened high blood pressure within six months of starting the medication, according to a new study published online today in Blood. (2019-10-03)
Exploring the risk of ALL in children with Down syndrome
Researchers discovered new clues that provide a better understanding of why children with Down syndrome have an increased risk of leukemia. (2019-09-24)
Changes in internal medicine subspecialty choices of women, men
This study used enrollment data to examine changes in the internal medicine subspecialty choices of women and men from 1991 to 2016. (2019-09-23)
Preclinical study reveals the impact of age on immunotherapy treatment for breast cancer
In order to understand the influence of aging on the effectiveness of immune checkpoint blockade therapy, researchers from Brigham and Women's Hospital, the Dana Farber Cancer Institute, and Harvard Medical School conducted preclinical studies using younger and older mice with triple negative breast cancer, finding that age affects the efficacy of ICB therapy. (2019-09-06)
How natural genetic differences can affect heart health
New study identifies genetic variants that may alter platelet function in cardiovascular disease (2019-09-04)
Having a parent, sibling, or child with blood cancer increases one's own risk
New data suggest that people who have a parent, sibling, or child with blood cancer have a higher likelihood of being diagnosed with the disease. (2019-08-08)
Uncovering secrets of bone marrow cells and how they differentiate
Researchers mapped distinct bone marrow niche populations and their differentiation paths for the bone marrow factory that starts from mesenchymal stromal cells and ends with three types of cells -- fat cells, bone-making cells and cartilage-making cells. (2019-07-31)
Postpartum transfusions on the rise, carry greater risk of adverse events
Women who receive a blood transfusion after giving birth are twice as likely to have an adverse reaction related to the procedure, such as fever, respiratory distress, or hemolysis (destruction of red blood cells), compared with non-pregnant women receiving the same care, according to a new study published today in Blood Advances. (2019-07-31)
New technique helps create more personalized therapies for people with advanced cancers
Using an ultra-sensitive and high-throughput isolation technology, UCLA researchers were able to characterize and identify the neoantigens driving the antitumor responses in a patient. (2019-07-22)
Many of the deadliest cancers receive the least amount of research funding
Many of the deadliest or most common cancers get the least amount of nonprofit research funding, reports a new Northwestern Medicine study. (2019-07-18)
Adding immunotherapy after initial treatment can benefit metastatic lung cancer patients
Treating metastatic non-small cell lung cancer (NSCLC) patients with the immunotherapy drug pembrolizumab after they've completed locally ablative therapy almost tripled the median progression-free survival (PFS) compared to the historical average. (2019-07-11)
Cardiac toxicity risk factors identified with relapsed multiple myeloma therapy
More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study published June 12, 2019 in Journal of Clinical Oncology. (2019-06-13)
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