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Current Immune response News and Events

Current Immune response News and Events, Immune response News Articles.
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Scientists show how parasitic infection causes seizures, psychiatric illness for some
In a new study published in GLIA , Virginia Tech neuroscientists at the Fralin Biomedical Research Institute at VTC describe how the common Toxoplasma gondii parasite prompts the loss of inhibitory signaling in the brain by altering the behavior of nearby cells called microglia. (2020-04-02)
Understanding the HIV-1 rev regulatory axis may help researchers to halt AIDS progression
HIV infection and replication within a human cell is a complex mechanism that involves multiple steps and several biochemical factors such as nucleic acids and proteins. (2020-03-31)
Cancer treatment with immune checkpoint inhibitors may lead to thyroid dysfunction
Thyroid dysfunction following cancer treatment with new treatments called immune checkpoint inhibitors is more common than previously thought, according to research that was accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and will be published in a special supplemental section of the Journal of the Endocrine Society. (2020-03-31)
Individuals taking class of steroid medications at high risk for COVID-19
Individuals taking a class of steroid hormones called glucocorticoids for conditions such as asthma, allergies and arthritis on a routine basis may be unable to mount a normal stress response and are at high risk if they are infected with the virus causing COVID-19, according to a new editorial published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2020-03-31)
Less expensive, more effective pneumonia vaccines are tested in humans
Developed by researchers at the Butantan Institute (Brazil) and Boston Children's Hospital, part of the Harvard Medical School (USA), the innovation is capable of providing protection against all serotypes of the bacterium Streptococcus pneumoniae. (2020-03-31)
Advances in production of retinal cells for treating blindness
Researchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. (2020-03-30)
Drug used for liver disease also affects C. diff life cycle, reduces inflammation in mice
Researchers have found that a commonly used drug made from secondary bile acids can affect the life cycle of Clostridioides difficile (C. diff) in vitro and reduce the inflammatory response to C. diff in mice. (2020-03-30)
Researchers discover potential boost to immunotherapy
Mount Sinai researchers have discovered a pathway that regulates special immune system cells in lung cancer tumors, suppressing them and allowing tumors to grow. (2020-03-30)
'Living drug factories' might treat diabetes and other diseases
Chemical engineers have developed a way to protect transplanted drug-producing cells from immune system rejection. (2020-03-30)
Biological 'atlas' shows dual personality for immune cells that cause Type 1 diabetes
Scientists at St. Jude Children's Research Hospital mapped the epigenetic controls on T cells, which could aid Type 1 diabetes diagnosis and treatment, as well as cancer immunotherapy. (2020-03-30)
How to boost immune response to vaccines in older people
Identifying interventions that improve vaccine efficacy in older persons is vital to deliver healthy ageing for an ageing population. (2020-03-27)
Experiments in mice and human cells shed light on best way to deliver nanoparticle therapy for cancer
Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively -- allowing the nanoparticles to diffuse into tumors and become held in place, or actively -- adding a targeted anti-cancer molecule to bind to specific cancer cell receptors and, in theory, keep the nanoparticle in the tumor longer. (2020-03-26)
Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new University of Wisconsin-Madison study shows. (2020-03-26)
Destroying DNA to save the genome -- study offers new insights into sepsis and its treatment
Sepsis is a life-threatening condition that kills millions annually; it is poorly understood and has no specific treatment. (2020-03-26)
Brake on immune activity identified, raising new possibilities for anticancer therapy
Researchers at the Lewis Katz School of Medicine at Temple University and Fox Chase Cancer Center show for the first time that a molecule called EGR4 -known mainly for its role in male fertility -- serves as a critical brake on immune activation. (2020-03-25)
How tissues harm themselves during wound healing
Researchers from Osaka University discovered that increased expression of Rbm7 in apoptotic tissue cells results in the recruitment of segregated-nucleus-containing atypical monocytes, leading to tissue fibrosis. (2020-03-25)
New research shows which ovarian cancer patients won't benefit from immune-PARP combo
In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven't been able to predict which patients won't benefit from the treatment and should explore other options. (2020-03-19)
Alzheimer's disease: Inflammation triggers fatal cycle
An immune reaction in the brain seems to play a major role in the development of Alzheimer's disease. (2020-03-18)
New technique has potential to protect oranges from citrus greening
Citrus greening, also called Huanglongbing (HLB), is devastating the citrus industry. (2020-03-18)
COVID-19: The immune system can fight back
Researchers at the Peter Doherty Institute for Infection and Immunity (Doherty Institute) were able to test blood samples at four different time points in an otherwise healthy woman in her 40s, who presented with COVID-19 and had mild-to-moderate symptoms requiring hospital admission. (2020-03-17)
Novel high-density microarray patch (HD-MAP) can deliver vaccines directly to the skin
Vaxxas announced the publication in the journal PLoS Medicine of groundbreaking clinical research indicating the broad immunological and commercial potential of Vaxxas' novel high-density microarray patch (HD-MAP). (2020-03-17)
New understanding of immune modulator interleukin-2 guides drug discovery
The signaling molecule interleukin-2 (IL-2) has long been known to have powerful effects on the immune system, but efforts to harness it for therapeutic purposes have been hampered by serious side effects. (2020-03-17)
'Natural killer' cells could halt Parkinson's progression
Researchers at the University of Georgia's Regenerative Bioscience Center and their colleagues have found that 'natural killer' white blood cells could guard against the cascade of cellular changes that lead to Parkinson's disease and help stop its progression. (2020-03-17)
A new strategy for the management of inflammatory pain
A group of researchers from Charité - Universitätsmedizin Berlin has discovered a new mechanism of long-lasting pain relief. (2020-03-16)
Blood stem cells boost immunity by keeping a record of previous infections
A Franco-German research team led by Prof. Michael Sieweke, from the Center for Regenerative Therapies TU Dresden (CRTD) and the Center of Immunology of Marseille Luminy (CNRS, INSERM, Aix-Marseille University), today uncovered a surprising property of blood stem cells: not only do they ensure the continuous renewal of blood cells and contribute to the immune response triggered by an infection, but they can also remember previous infectious encounters to drive a more rapid and more efficient immune response in the future. (2020-03-13)
Research on the fossil
Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany, succeeded for the first time ever in describing in lampreys the mechanistic basis with which the different receptor genes in these ancient creatures are assembled to form the receptor on the surface of immune cells. (2020-03-13)
Receptors for the immune defence
Max Planck researchers investigate the function of immune genes in primitive mammals. (2020-03-13)
Cancer: The immune system attacks tumors remotely
How does the immune system act to limit tumor development? (2020-03-12)
Gasdermin E: A new approach to cancer immunotherapy that could have broad reach
Tumors have various ways of dodging attacks by the immune system. (2020-03-11)
Sensing infection, suppressing regeneration
UIC researchers describe an enzyme that blocks the ability of blood vessel cells to self-heal. (2020-03-11)
LJI scientists identify potential targets for immune responses to novel coronavirus
Publishing in the March 16, 2020, online issue of Host, Cell and Microbe, a team of researchers at La Jolla Institute for Immunology, in collaboration with researchers at the J. (2020-03-11)
Immune cells against Alzheimer's?
German researchers have developed a novel, experimental approach against Alzheimer's. (2020-03-10)
Babies born prematurely can catch up their immune systems, study finds
Researchers from King's College London & Homerton University Hospital have found babies born before 32 weeks' gestation can rapidly acquire some adult immune functions after birth, equivalent to that achieved by infants born at term. (2020-03-09)
Levels of sBTLA proteins as potential marker of overall survival of liver cancer patients
Researchers at Osaka City University Graduate School of Medicine introduced sorafenib to patients with advanced stages of the liver cancer hepatocellular carcinoma (HCC) and measured the amount of 16 circulating soluble immune checkpoint proteins. (2020-03-09)
Rejuvenating the immune system supports brain repair after injury
Researchers have identified a major shift in how to treat brain injuries, after rejuvenating immune cells to support the repair process. (2020-03-08)
Gut bacteria can penetrate tumors and aid cancer therapy, study suggests
Researchers at the University of Texas Southwestern Medical Center and University of Chicago have discovered that bacteria that usually live in the gut can accumulate in tumors and improve the effectiveness of immunotherapy in mice. (2020-03-06)
Specialized helper cells contribute to immunological memory
Helper T cells play an important role in the immune response against pathogens. (2020-03-06)
Could cancer immunotherapy success depend on gut bacteria?
Gut bacteria can penetrate tumor cells and boost the effectiveness of an experimental immunotherapy that targets the CD47 protein. (2020-03-06)
Engineered bone marrow cells slow growth of prostate and pancreatic cancer cells
In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response. (2020-03-05)
New drug combination could support better cancer treatments
Researchers have identified a promising new drug combination that could significantly help the immune system target cancer cells and kill them. (2020-03-05)
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