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Current Immune response News and Events

Current Immune response News and Events, Immune response News Articles.
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Hackensack Meridian CDI scientists find one-two punch for preclinical cancer models
Research findings published Aug. 14, 2020 in the journal Cancer Research suggest that since some cancer treatments can be undermined by epigenetic changes (altered DNA methylation affecting gene expression) in cancer cells before the treatments are even administered, a worthwhile strategy is to administer an epigenetically-acting drug - which can pave the way for more effective subsequent use of immune-acting cancer treatments. (2020-09-30)
Investigational COVID-19 vaccine well-tolerated, generates immune response in older adults
A Phase 1 trial of an investigational mRNA vaccine to prevent SARS-CoV-2 infection has shown that the vaccine is well-tolerated and generates a strong immune response in older adults. (2020-09-30)
Innate lymphoid cells regenerate within lung
Max Planck researcher Dominic Grün teamed up with colleagues from Würzburg headed by Georg Gasteiger and generated a comprehensive atlas of Innate lymphoid cells (ILCs) of the lung. (2020-09-30)
Scientists propose immune cocktail therapy to boost cancer-immunity cycle in multiple aspects
A research team led by Prof. TIAN Huayu from the Changchun Institute of Applied Chemistry (CIAC) of the Chinese Academy of Sciences proposed an innovative immune cocktail therapy that combined ICT along with other therapeutic approaches. (2020-09-30)
Mussels connect antibodies to treat cancer
POSTECH research team develops innovative local anticancer immunotherapy technology using mussel protein. (2020-09-29)
An in-depth analysis of antibody responses to SARS-CoV-2
Using a technology called VirScan to study coronavirus antibody responses in a large cohort of SARS-CoV-2-infected and control individuals, researchers identified epitopes recognized by a large fraction of COVID-19 patients, epitopes cross-reactive with antibodies developed in response to other human coronaviruses, and 10 epitopes likely recognized by neutralizing antibodies. (2020-09-29)
VirScan offers new insights into COVID-19 antibody response
VirScan, a technology that can determine which of more than 1,000 different viruses have infected a person, can now also detect evidence of infection from coronaviruses, including SARS-CoV-2. (2020-09-29)
Inflammatory gene provides clue to obesity risk
A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found. (2020-09-29)
Prostate cancer: immunotherapy offers hope
An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasised, castration-resistant prostate cancer. (2020-09-29)
In a field where smaller is better, researchers discover the world's tiniest antibodies
Researchers at the University of Bath in the UK and biopharma company UCB have found a way to produce miniaturised antibodies, opening the way for a potential new class of treatments for diseases. (2020-09-29)
New genetic knowledge on the causes of severe COVID-19
A proportion of the most severe COVID-19 cases can be explained by genetic defects in the patients' immune system. (2020-09-29)
Successful Dartmouth TB vaccine moves forward after phase 2 trial
Results from the Phase 2 trial of the DAR-901 tuberculosis (TB) vaccine were announced today by investigators at Dartmouth's Geisel School of Medicine and published in the journal Vaccine. (2020-09-29)
New research provides clues on optimizing cell defenses when viruses attack
Researchers studying interferons, immune response proteins released naturally by human cells when viruses are detected, have uncovered new details on the mechanisms underlying cell defenses. (2020-09-29)
Memory training for the immune system
The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. (2020-09-28)
Strong activation of anti-bacterial T cells linked to severe COVID-19
A type of anti-bacterial T cells, so-called MAIT cells, are strongly activated in people with moderate to severe COVID-19 disease, according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal Science Immunology. (2020-09-28)
A genetic variant that protects against Alzheimer's disease promotes immune cell functions
A new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer's disease, enhances several key functions of immune cells. (2020-09-25)
Adequate levels of vitamin D reduces complications, death among COVID-19 patients
Hospitalized COVID-19 patients who were vitamin D sufficient, with a blood level of 25-hydroxyvitamin D of at least 30 ng/mL (a measure of vitamin D status), had a significant decreased risk for adverse clinical outcomes including becoming unconscious, hypoxia (body starved for oxygen) and death. (2020-09-25)
Uncovering a 'suPAR' culprit behind kidney injury in COVID-19
A new observational study finds patients in the hospital for COVID-19 have high levels of soluble urokinase receptor (suPAR), an immune-derived pathogenic protein that is strongly predictive of kidney injury. (2020-09-24)
Scientists trace severe COVID-19 to faulty genes and an autoimmune condition
An international team led by Jean-Laurent Casanova has led to a breakthrough in understanding why only some people develop severe COVID-19: due to faulty genes or misguided antibodies, they lack type I interferons, proteins vital in protecting against viruses. (2020-09-24)
Scientists Discover Genetic and Immunologic Underpinnings of Some Cases of Severe COVID-19
New findings by scientists at the National Institutes of Health and their collaborators help explain why some people with COVID-19 develop severe disease. (2020-09-24)
Study reveals higher COVID-19 mortality in men could be explained by differences in circulating proteins and immune system cells
New research presented at the ESCMID Conference on Coronavirus Diseases (ECCVID, online 23-25 September) suggests that the higher risk of poor COVID-19 outcomes in men could be explained by differences in circulating proteins and immune system cells compared with women. (2020-09-24)
Scientists identify dozens of genes allowing cancer cells to evade the immune system
Cancer immunotherapy can be extremely successful but so far has only worked in a fraction of patients and tumour types. (2020-09-23)
Berry good news -- new compound from blueberries could treat inflammatory disorders
Inflammatory bowel disease (IBD), caused by chronic inflammation in the digestive tract linings, can be debilitating and life threatening. (2020-09-23)
Novel dual CAR T cell immunotherapy holds promise for targeting the HIV reservoir
A recent study published in the journal Nature Medicine, led by researchers James Riley, PhD, a professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, and Todd Allen, PhD, a professor of Medicine at Harvard Medical School and Group Leader at the Ragon Institute of MGH, MIT and Harvard, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection. (2020-09-23)
Children's immune response more effective against COVID-19
Children and adults exhibit distinct immune system responses to infection by the virus that causes COVID-19, a finding that helps explain why COVID-19 outcomes tend to be much worse in adults, researchers from Yale and Albert Einstein College of Medicine report Sept. (2020-09-22)
Targeting the treatment of autoimmune diseases
A team of researchers from Charité - Universitätsmedizin Berlin and the Deutsches Rheuma-Forschungszentrum (DRFZ) Berlin, a Leibniz Institute, have successfully treated two patients with the autoimmune disease systemic lupus erythematosus. (2020-09-22)
COVID-19 mortality rates higher among men than women
A new review article from Beth Israel Deaconess Medical Center (BIDMC) shows people who are biologically male are dying from COVID-19 at a higher rate than people who are biologically female. (2020-09-22)
Patients with COVID-19 may have higher risk of kidney injury
According to Jochen Reiser, MD, PhD, the Ralph C Brown MD professor and chairperson of Rush's Department of Internal Medicine, patients with COVID-19 experience elevated levels of soluble urokinase receptor (suPAR), an immune-derived pathogenic protein that is strongly predictive of kidney injury. (2020-09-22)
New vaccine strategy harnesses 'foot soldier' T-cells to protect against influenza
As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza. (2020-09-22)
Discovered: New resistance gene to devastating potato disease that caused Irish Famine
In a recent collaboration between the Chinese Academy of Agricultural Sciences and the James Hutton institute, scientists identified a diploid wild potato with a high resistance to Phytophthora infestans. (2020-09-21)
Study finds that children's immune response protects against COVID-19
The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults. (2020-09-21)
Long-term COVID-19 containment will be shaped by strength, duration of immunity
New research suggests that the impact of natural and vaccine-induced immunity will be key factors in shaping the future trajectory of the global coronavirus pandemic, known as COVID-19. (2020-09-21)
Modeling future COVID-19 cases under a variety of immune responses, and with or without vaccines
Researchers who adapted standard epidemiological models to explore how the COVID-19 pandemic trajectory might unfold in the next five years report diverse scenarios ranging from recurring severe epidemics to elimination. (2020-09-21)
Children with COVID-19 show different immune responses, but better outcomes than adults
A comparison of children and adults hospitalized with COVID-19 reveals pediatric patients, who had better outcomes and shorter hospital stays, displayed altered immune responses and more limited production of antibodies against infection. (2020-09-21)
Researchers find diminished response by 'killer' T cells in elderly COVID-19 patients
Although people of any age can become infected with SARS-CoV-2, the virus that causes COVID-19, elderly patients face a higher risk of severity and death than younger patients. (2020-09-21)
Increasing the effectiveness of cancer treatments: Anti-PD-L1 immunotherapy
Researh teams of Tokyo Medical and Dental University (TMDU) and Harvard Medical School (HMS) have uncovered how to increase the efficacy of anti-PD-L1 immunotherapy. (2020-09-18)
Increasing the effectiveness of immunotherapy against skin cancer
Researchers at the University of Bern have discovered a mechanism in the body's own immune system which is responsible for the maturation and activation of immune cells. (2020-09-18)
Removal of a gene could render lethal poxviruses harmless
The removal of one gene renders poxviruses - a lethal family of viral infections that are known to spread from animals to humans - harmless, a new study in the journal Science Advances reports. (2020-09-18)
Immune system may have another job -- combatting depression
An inflammatory autoimmune response within the central nervous system similar to one linked to neurodegenerative diseases such as multiple sclerosis (MS) has also been found in the spinal fluid of healthy people, according to a new Yale-led study comparing immune system cells in the spinal fluid of MS patients and healthy subjects. (2020-09-18)
Improving the efficacy of cellular therapies
A new study published in Nature Communications deepens the understanding of the development of T cell, an important component of the immune system. (2020-09-17)
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