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Current Immune response News and Events

Current Immune response News and Events, Immune response News Articles.
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Stem cells with 'dual identity' linked to loss of smell from sinus inflammation
In experiments with mice and human tissue samples, Johns Hopkins Medicine researchers report evidence that neuronal stem cells in the part of the nose responsible for the sense of smell transform themselves to perpetuate the long-term inflammation in chronic sinusitis. (2019-09-19)
Age-related decline in immune function takes sheep to the grave earlier
For the sheep of St. Kilda, growing old brings with it a late-life decline in immune resistance against pervasive parasitic worms, which greatly reduces the animal's chances of surviving overwinter, regardless of overall physiological condition. (2019-09-19)
Wild animals' immune systems decline with age, sheep study finds
It is well established that weakened immune systems in old age affect people's health and fitness, but a study suggests that it is also an issue for wild animals. (2019-09-19)
Extinct human species gave modern humans an immunity boost
Garvan researchers have discovered a gene variant that sheds new light on how human immunity was fine-tuned through history. (2019-09-18)
DNA 'origami' takes flight in emerging field of nano machines
'DNA mechanotechnology' is a new field to engineer DNA machines that generate, transmit and sense mechanical forces at the nanoscale. (2019-09-18)
How sleepless nights compromise the health of your gut
Why are individuals that have irregular schedules, such as night-shift workers, more susceptible to gut inflammation and obesity? (2019-09-18)
A promising HIV vaccine shows signs of cross-protective benefits
One of the most successful candidate HIV vaccines to date -- initially tested in Thailand, where it had modest effects -- showed surprisingly strong efficacy when evaluated in a South African cohort, where a different strain of HIV is known to circulate. (2019-09-18)
Synthetic cells capture and reveal hidden messages of the immune system
New research is highly relevant to how antibodies are made in response to infections, vaccines and in autoimmunity due to the its analysis of a signal that is associated with hyper IgM syndrome, a genetic deficiency of CD40 ligand (CD40L) that results in profound immunodeficiency. (2019-09-17)
Researchers find building mutations into Ebola virus protein disrupts ability to cause disease
Creating mutations in a key Ebola virus protein that helps the deadly virus escape from the body's defenses can make the virus unable to produce sickness and activate protective immunity in the infected host, according to a study by the Institute for Biomedical Sciences at Georgia State University. (2019-09-17)
Mutant live attenuated Ebola virus immunizes non-human primates
Inoculation with an Ebola virus that has mutations in a protein called VP35 does not cause disease and elicits protection in monkeys, researchers show Sept. (2019-09-17)
Immune response depends on mathematics of narrow escapes
The way immune cells pick friends from foes can be described by a classic maths puzzle known as the 'narrow escape problem'. (2019-09-16)
In mice: Transplanted brain stem cells survive without anti-rejection drugs
In experiments in mice, Johns Hopkins Medicine researchers say they have developed a way to successfully transplant certain protective brain cells without the need for lifelong anti-rejection drugs. (2019-09-16)
Subgroup of colorectal cancer patients ID'd: Do poorly, could benefit from immunotherapy
While the medical community agrees immune cells inside a tumor leads to improved health outcome, for a subset of colorectal cancer patients, having too much of a good thing is a strong predictor of disease recurrence and reduced chances of survival. (2019-09-16)
Too much of a good thing: Overactive immune cells trigger inflammation
Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. (2019-09-16)
Genetic mutation appears to protect some people from deadly MRSA
An inherited genetic tendency appears to increase the likelihood that a person can successfully fight off antibiotic-resistant staph infections, according to a study led by Duke Health researchers. (2019-09-16)
Needle-free flu vaccine patch effective in early study
A new needle-free flu vaccine patch revved up the immune system much like a traditional flu shot without any negative side effects. (2019-09-16)
B cells linked to immunotherapy for melanoma
Immunotherapy uses our body's own immune system to fight cancer. (2019-09-13)
How new loops in DNA packaging help us make diverse antibodies
It's long been known that our immune cells mix and match bits of genetic code to make new kinds of antibodies to fight newly encountered threats. (2019-09-13)
How IL-6 allows the immune response to develop for a key cell, the T follicular helper
A preclinical study published in Science Immunology shows how the interplay of two interleukin signaling proteins, IL-6 and IL-2, affects the development of T follicular helper cells and germinal centers. (2019-09-13)
Humans more unique than expected when it comes to digesting fatty meals
People have very individualized inflammatory responses to eating a high-fat meal. (2019-09-12)
Meet the molecule that helps stressed cells decide between life and death
St. Jude Children's Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum. (2019-09-11)
A liquid biopsy test can identify patients who may respond to immune checkpoint blockade
A new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it could help determine which patients are likely to respond to immune checkpoint inhibitors. (2019-09-10)
An overactive cerebellum causes issues across the brain
Kyoto University researchers found that acute cerebellar inflammation puts the structure in an 'overexcited state, resulting in temporary decrease in motivation and sociability indicative of 'depression-like behavior. (2019-09-10)
Protein mapping pinpoints why metastatic melanoma patients do not respond to immunotherapy
Tel Aviv University and Sheba Medical Center researchers say they have discovered why more than half of patients with metastatic melanoma do not respond to immunotherapy cancer treatments. (2019-09-09)
New research from Alkema lab shows how stress can weaken defenses
Research from the lab of Mark Alkema, Ph.D., at UMass Medical School, shows how a dynamic regulation of a stress neurohormone regulates the trade-off between acute and long-term stress responses. (2019-09-09)
One-third of young children admitted to intensive care for sepsis show PTSD symptoms years later
Doctors have found that children who have been in Intensive Care Units (ICUs) for sepsis have a significantly increased risk of post-traumatic stress disorder (PTSD), with around one-third showing PTSD symptoms. (2019-09-07)
Preclinical study reveals the impact of age on immunotherapy treatment for breast cancer
In order to understand the influence of aging on the effectiveness of immune checkpoint blockade therapy, researchers from Brigham and Women's Hospital, the Dana Farber Cancer Institute, and Harvard Medical School conducted preclinical studies using younger and older mice with triple negative breast cancer, finding that age affects the efficacy of ICB therapy. (2019-09-06)
Disrupting the gut microbiome may affect some immune responses to flu vaccination
The normal human gut microbiome is a flourishing community of microorganisms, some of which can affect the human immune system. (2019-09-06)
Researchers characterize lung inflammation associated with some cancer immnunotherapy
Immune checkpoint inhibitors uses the immune system to fight cancer. (2019-09-05)
'Tiny fat bubbles' can boost immunity, calm disease
People living with inflammatory autoimmune disease could benefit from an 'immune system reboot', and researchers have isolated specific cells to target. (2019-09-05)
Potential vaccine treats and prevents deadly streptococcal toxic shock
A new vaccine developed by Griffith University Institute for Glycomics researchers has the potential to treat and prevent toxic shock caused by invasive streptococcal disease, which kills more than 160,000 people every year. (2019-09-04)
Identification of new populations of immune cells in the lungs
In an article published in Nature Communications, the Immunophysiology Laboratory of the GIGA Institute, headed by Prof. (2019-09-03)
Researchers identify biomarker to predict if someone infected with malaria will get sick
Increased p53, the well-known tumor-suppressor protein, can predict whether malaria-infected children will develop fever or other symptoms, suggests a study publishing Sept. (2019-09-03)
Mumps study shows immunity gaps among vaccinated people
Immunity against mumps virus appears insufficient in a fraction of college-aged people who were vaccinated in childhood, research from Emory and CDC indicates. (2019-09-02)
Bacteria in pneumonia attack using bleaching agent
Research shows that bacteria use hydrogen peroxide to weaken the immune system and cause pneumonia. (2019-09-02)
Discovery paves the way for earlier detection of type 1 diabetes
In new research published in Science Immunology, scientists at Scripps Research have discovered what may be the earliest possible biological marker of type 1 diabetes, formerly known as juvenile type 1 diabetes. (2019-08-30)
Danish-American research presents new ways of developing treatment of chronic inflammation
Researchers from Aarhus University Hospital and Aarhus University in Denmark in collaboration with researchers from Colorado in the United States have found a new way to treat the inflammation involved in chronic diseases such as psoriasis, asthma and HIV. (2019-08-30)
Delivering immunotherapy directly to brain tumors
A new study published this week gives insight into how cancer immunotherapies might one day be delivered directly to the brain in order to treat brain tumors. (2019-08-29)
A protective factor against Alzheimer's disease?
Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the Institute for Stroke and Dementia Research (ISD) at the University Hospital of the Ludwig-Maximilians-Universität (LMU) in Munich have found that a protein called TREM2 could positively influence the course of Alzheimer's disease. (2019-08-29)
People's initial immune response to dengue fever analyzed
Researchers have come one step closer to understanding how our immune system responds to acute dengue fever, a disease that has affected hundreds of thousands of people in Southeast Asia this summer alone. (2019-08-29)
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