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Current Immune response News and Events

Current Immune response News and Events, Immune response News Articles.
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Lupus strongly linked to imbalances in gut microbiome
The disease systemic lupus erythematosus (SLE) -- marked by the attack on joints, skin, and kidneys by the body's immune system -- is linked to an abnormal mix of bacteria in the gut. (2019-02-19)
Revealed: How the 'Iron Man' of immune cells helps T cells fight infection
The immune system's killer T cells are crucial in fighting viral infections. (2019-02-19)
First molecular test that selects immunotherapy for kidney cancer
National Cancer Centre Singapore and Lucence Diagnostics Announce First Molecular Test that Selects Immunotherapy for Kidney Cancer. (2019-02-19)
Scientists create new map of brain's immune system
A team of researchers under the direction of the Medical Center -- University of Freiburg has created an entirely new map of the brain's own immune system in humans and mice. (2019-02-19)
Plants can skip the middlemen to directly recognize disease-causing fungi
Scientists at the Max Planck Institute for Plant Breeding Research in Cologne have revealed that direct physical associations between plant immune proteins and fungal molecules are widespread during attempted infection. (2019-02-19)
Food allergies and multiple sclerosis: study reveals a new link
Investigating the correlation between allergy and inflammatory disease activity, a team of investigators from Brigham and Women's Hospital has found new evidence connecting food allergies and relapses of multiple sclerosis. (2019-02-19)
New machine learning technique rapidly analyzes nanomedicines for cancer immunotherapy
With their ability to treat a wide a variety of diseases, spherical nucleic acids (SNAs) are poised to revolutionize medicine. (2019-02-19)
T-cell receptor diversity may be key to treatment of follicular lymphoma, Mayo study finds
Healthy white blood cells, called ''T-cells,'' play a crucial role in how the body fights follicular lymphoma. (2019-02-19)
Small cell lung cancer may respond to combination of immunotherapy and DNA damage repair inhibitors
MD Anderson researchers discovered that a combination of immunotherapy and targeted therapies that block normal DNA damage repair, such as PARP inhibitors, achieved dramatic tumor reduction in mouse models of small cell lung cancer. (2019-02-18)
Single CRISPR treatment provides long-term benefits in mice
Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD) -- for more than a year in mice, despite observed immune responses and alternative gene editing outcomes. (2019-02-18)
CRISPR gene editing makes stem cells 'invisible' to immune system
UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally 'invisible' to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants. (2019-02-18)
Smoking may limit body's ability to fight dangerous form of skin cancer
Melanoma patients with a history of smoking cigarettes are 40 percent less likely to survive their skin cancer than people who have never smoked, according to a new report funded by Cancer Research UK. (2019-02-17)
Immune stimulant molecule shown to prevent cancer
An immune checkpoint molecule developed for cancer immunotherapy also protects against future development of multiple types of cancer when administered by itself. (2019-02-15)
Linking sensing to signaling during plant immunity
A new study by researchers at the Max Planck Institute for Plant Breeding Research (MPIPZ) in Cologne has revealed that a previously unappreciated structural feature underlies the ability of the plant immune molecule EDS1 to provide a timely defense boost against pathogens. (2019-02-15)
Why some brain tumors respond to immunotherapy
Fewer than 1 in 10 patients with glioblastoma -- the most common type of brain cancer -- respond to immunotherapy; a new study reveals how to detect patients who may respond. (2019-02-15)
Antidepressant could stop deadly sepsis, study suggests
An antidepressant drug used to treat obsessive-compulsive disorder could save people from deadly sepsis, new research suggests. (2019-02-14)
Noninvasive liquid biopsies rapidly, accurately determine response to cancer treatment
Results of two clinical studies have added to evidence that blood-based liquid biopsies can accurately track lung cancer treatment responses by measuring circulating tumor DNA (ctDNA) during immunotherapy and related treatments. (2019-02-13)
VUMC researchers, supercomputing effort reveal antibody secrets
Using sophisticated gene sequencing and computing techniques, researchers at Vanderbilt University Medical Center (VUMC) and the San Diego Supercomputer Center have achieved a first-of-its-kind glimpse into how the body's immune system gears up to fight off infection. (2019-02-13)
Human cells can also change jobs
Biology textbooks teach us that adult cell types remain fixed in the identity they have acquired upon differentiation. (2019-02-13)
German researchers discover how sleep can fight infection
Researchers in Germany have discovered why sleep can sometimes be the best medicine. (2019-02-12)
A bioengineered factory for T-cells
Harvard engineers and stem cell biologists have developed an injectable sponge-like gel that enhances the production T-cells after a bone marrow transplant. (2019-02-11)
Interaction between immune factors triggers cancer-promoting chronic inflammation
A Massachusetts General Hospital research team has identified interaction between two elements of the immune system as critical for the transformation of a protective immune response into chronic, cancer-promoting inflammation. (2019-02-11)
Western diet may increase risk of severe sepsis, death, study finds
A Western diet high in fat and sugar can pack on the pounds. (2019-02-11)
Masterswitch discovered in body's immune system
Scientists have discovered a critical part of the body's immune system with potentially major implications for the treatment of some of the most devastating diseases affecting humans. (2019-02-11)
How a fungus can cripple the immune system
An international research team led by Professor Oliver Werz of Friedrich Schiller University, Jena, has now discovered how the fungus knocks out the immune defenses, enabling a potentially fatal fungal infection to develop. (2019-02-08)
Mosaic-like gene deletion and duplication pattern shaping the immune system discovered
A team of researchers from Bar-Ilan University has developed a computational tool for analyzing genetic changes related to the immune system. (2019-02-07)
Duke-NUS study: Interaction between two immune cell types could be key to better dengue vaccines
A sentinel immune cell in the skin surprises researchers by forming a physical connection with a virus-killing T cell. (2019-02-07)
Study finds HIV+ cancer patients benefit from immunotherapy
The immunotherapy that has revolutionized treatment of many cancers appears to offer similar benefit to cancer patients living with HIV. (2019-02-07)
Immunotherapy drug used as 1st-line therapy for Merkel cell carcinoma improved survival
A multi-center phase II clinical trial investigating pembrolizumab as a first-line and programmed cell death-1 therapy in patients with advanced Merkel cell carcinoma reports lasting tumor control, generally manageable side effects and improved overall survival. (2019-02-07)
Immunotherapy appears better than chemotherapy for aggressive type of skin cancer
The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy. (2019-02-07)
Tak Mak lab discovers how the immune system 'thinks'
New research from the laboratory of cancer scientist Dr. Tak Mak, renowned for cloning the human T-cell receptor, has demonstrated that immune cells make brain chemicals to fight off infections. (2019-02-07)
Feinstein CEO, global researchers show significance of neurotransmitter in viral infection
Feinstein Institute for Medical Research President and CEO Kevin J. (2019-02-07)
Finding clues to a functional HIV cure
George Mason University's Yuntao Wu's research team has identified a measurable indicator that could prove instrumental in the fight against HIV. (2019-02-07)
Micromotors deliver oral vaccines
Vaccines have saved millions of lives, but nobody likes getting a shot. (2019-02-06)
New therapy for amyotrophic lateral sclerosis successfully tested on mice
A team from Université Laval and the CERVO Brain Research Centre has demonstrated the efficacy in mice of a new therapy that addresses the main manifestation of amyotrophic lateral sclerosis (ALS). (2019-02-06)
Association between EMS response time and motor vehicle crash mortality
Motor vehicle crashes are a leading cause of death and injury in the United States. Emergency medical service (EMS) response time is a factor with the potential to influence survival.  This study examined EMS response times to motor vehicle crashes in nearly 2,300 US counties from 2013 to 2015. (2019-02-06)
NSAID impairs immune response in heart failure, worsens heart and kidney damage
Non-steroidal anti-inflammatory drugs, or NSAIDs, are widely known as pain-killers and can relieve pain and inflammation. (2019-02-06)
HIV drug could treat Alzheimer's, age-associated disorders
Research led by Brown found that blocking retrotransposon activity with a generic HIV/AIDS medication significantly reduces age-related inflammation in old mice and senescent human cells, providing hope for treating age-associated disorders. (2019-02-06)
Escort service: The role of immune cells in the formation of metastases
Tumor cells use a certain type of immune cells, the so-called neutrophils, to enhance their ability to form metastases. (2019-02-06)
Nullifying protein YTHDF1 enhances anti-tumor response
Identifying molecular pathways that boost the immune response to tumor neoantigens opens up new ways to develop and amplify cancer immunotherapy. (2019-02-06)
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