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Current Immune system News and Events

Current Immune system News and Events, Immune system News Articles.
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UCLA study shows inhibition of gene helps overcome resistance to immunotherapy
A new study helps explain why some people with advanced cancer may not respond to one of the leading immunotherapies, PD-1 blockade, and how a new combination approach may help overcome resistance to the immunotherapy drug. (2019-12-09)
Treatment with PD-1 prior to stem cell transplant is safe for Hodgkin lymphoma patients
A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma. (2019-12-09)
Researchers identify 'Achilles' heel' of drug-resistant superbug
Researchers at The University of Texas Health Science Center at Houston (UTHealth) have identified a protein that allows vancomycin-resistant enterococci, a deadly superbug, to defy antibiotic treatment and immune system attacks. (2019-12-09)
Giving common antibiotic before radiation may help body fight cancer
The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy. (2019-12-09)
Probiotics and prebiotics work differently in girls and boys according to piglet study
Baby boy's and girl's immune systems respond differently to prebiotics and probiotics, according to new research. (2019-12-08)
Taming chronic inflammation may reduce illness, save lives
Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide. (2019-12-05)
Immune checkpoint therapy for ER+ breast cancers, a missed opportunity?
A subset of endocrine therapy-resistant luminal B breast cancers activates immune responses that could be amenable to manipulation with immunotherapy. (2019-12-05)
Immune system can be coaxed into selecting key antibodies to fight HIV
Researchers have cleared a major obstacle in the development of an HIV vaccine, proving in animal models that effective, yet short-lasting antibodies can be coaxed into multiplying as a fighting force against the virus (2019-12-05)
A new study reveals the function of corpora amylacea to remove brain waste substances
An article published in Proceedings of the National Academy of Sciences (PNAS) describes a new pathway in the central nervous system to expel waste substances from the brain through the creation of corpora amylacea (CA), aggregates formed by glucose polymers amassing waste products. (2019-12-04)
The gut may be involved in the development of multiple sclerosis
It is incompletely understood which factors in patients with multiple sclerosis act as a trigger for the immune system to attack the brain and spinal cord. (2019-12-04)
Study reveals dynamics of crucial immune system proteins
Of the many marvels of the human immune system, the processing of antigens by the class I proteins of the major histocompatability complex (MHC-I) is among the most mind-boggling. (2019-12-03)
Immunology -- Activation by breakdown
Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule -- and both derivatives are generated by the same enzyme. (2019-12-02)
Researchers find protein promotes cancer, suppresses anti-tumor immunity
Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes, TBK1, also can fuel cancer development and suppress immune response to the disease. (2019-12-02)
Immunology: Activation by breakdown
Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme. (2019-11-29)
New method accelerates development of protein therapeutics
Northwestern Engineering researchers have developed a quick, cell-free system to create biosynthetic pathways to build and study sugar structures. (2019-11-27)
Early antiretroviral treatment shrinks the HIV reservoir in infected infants
Starting antiretroviral therapy within hours of birth drastically shrinks the reservoir of HIV virus -- an important step in efforts to cure infections -- and improves antiviral immune responses in newborns with HIV, shows a two-year study of a unique cohort of ten infants in Botswana. (2019-11-27)
Regulator of plant immunity tagged
Discovery of signaling intermediary could lead to more pest-resistant crops. (2019-11-26)
Newborn immune system detects harmful skin bacteria
In a study of young mice, UC San Francisco scientists found that an early-life window of immune tolerance available to a normally harmless bacterial species is firmly closed to another, often pathogenic species -- one that is a leading cause of drug-resistant skin infections in the US and occasional source of 'flesh-eating' necrosis. (2019-11-26)
Linking wound healing and cancer risk
When our skin is damaged, a whole set of biological processes springs into action to heal the wound. (2019-11-26)
A protein tag to study the immune system
Researchers from VIB-UGent Center for Medical Biotechnology, University of Iowa (USA) and other collaborators, developed a novel approach to better understand a basic defense mechanism of our immune system. (2019-11-26)
Simulating amino acid starvation may improve dengue vaccines
In a new paper in Science Signaling, researchers at the University of Hyderabad in India and the Cornell University College of Veterinary Medicine show that a plant-based compound called halofuginone improves the immune response to a potential vaccine against dengue virus. (2019-11-26)
The 'Signal Cell' relaying microbiota signals discovered
Prof. Seung-Woo Lee and his research team from POSTECH revealed the microbiota signal mechanism. (2019-11-25)
Potent antimicrobial found that shows promise in fighting staph infections
After screening thousands of small molecules, the research team discovered a potent new antimicrobial they are calling MAC-545496 that is active against MRSA. (2019-11-25)
Encouraging normal liver cells to fight cancer
A study conducted at the VIB-KU Leuven Center for Cancer Biology discovered that healthy liver tissue surrounding a tumor activates a defence mechanism that restrains tumor growth. (2019-11-25)
Consistent gene changes in Alzheimer's disease across studies
A comparison of mouse Alzheimer's disease models shows changes in the number of cells and the genes they express remain consistent throughout all stages of the disease. (2019-11-25)
Gut microbes alter characteristics of norovirus infection
The highly contagious norovirus causes diarrhea and vomiting and is notorious for spreading rapidly through densely populated spaces, such as cruise ships, nursing homes, schools and day care centers. (2019-11-25)
Discovery paves the way for blocking malaria transmission in Brazil
Research that will be presented today at FAPESP Week France suggests that bacteria present in the intestine of the Anhopheles darlingi mosquito influence the development of the parasite that causes the disease in the insect's body and the chances of transmission to humans. (2019-11-22)
Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant...
Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system. (2019-11-22)
Researchers uncover critical metabolic switch for inflammatory diseases
A research team in Trinity College Dublin has uncovered a critical role for a protein called 'PKM2' in the regulation of immune cell types at the heart of multiple inflammatory diseases. (2019-11-21)
Magnesium deprivation stops pathogen growth
When pathogens invade the cells, our body combats them using various methods. (2019-11-21)
Wound healing in mucous tissues could ward off AIDS
Wound healing in mucous tissues during early infection by Simian Immunodeficiency Virus guards some primate species against developing AIDS, Both HIV and SIV provoke an immune response that injures tissues surrounding the intestine, African green monkeys with SIV quickly repair their mucous tissues. (2019-11-21)
Successful study of Swedish vaccine candidate against diarrhea
University of Gothenburg reports first successful results of the oral, inactivated vaccine candidate ETVAX against enterotoxigenic E. coli diarrhea in a placebo-controlled phase I/II study in infants and children from 6 months to 5 years of age in Bangladesh. (2019-11-20)
Creating viral targets can weaken HIV vaccination
Vaccination against HIV/SIV can backfire if the vaccine induces the wrong kind of immune response. (2019-11-20)
How do gliomas evolve?
The Glioma Longitudinal Analysis (GLASS) Consortium characterized diffuse glioma cells both before and after therapy to characterize how they change and why this form of malignant brain cancer is so difficult to treat. (2019-11-20)
Complex organ models grown in the lab
Scientists at the University of Würzburg have successfully produced human tissues from stem cells. (2019-11-19)
A new pathway to 'reprogram' killer cells
Killer cells of the immune system detect and kill infected cells or cancer cells. (2019-11-19)
Evidence in mice that childhood asthma is influenced by the neurotransmitter dopamine
Neurons that produce the neurotransmitter dopamine communicate with T cells to enhance allergic inflammation in the lungs of young mice but not older mice, researchers report Nov. (2019-11-19)
Malaria discovery could lead to better HIV and lupus treatments
A discovery about how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus, say Melbourne researchers. (2019-11-19)
Consuming cholera toxin counteracts age-associated obesity
Here the research team tested a safe and well-established microbe-based immune adjuvant to restore immune homeostasis and counteract inflammation-associated obesity in animal models. (2019-11-19)
Subtle changes, big effects
According to the chaos theory in mathematics, a minute change such as the 'flap of a butterfly's wing' could cause huge changes elsewhere. (2019-11-18)
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