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Current Immune system News and Events

Current Immune system News and Events, Immune system News Articles.
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Scientists map genes controlling immune system 'brakes'
Researchers at Gladstone Institutes, in collaboration with scientists at UC San Francisco (UCSF) and the Technical University of Munich (TUM), have mapped out the networks of genes that help differentiate regulatory T cells from other T cells. (2020-10-01)
Feeding C-section newborns their mother's poop may help build healthy microbiota
A paper published October 1, 2020 in the journal Cell suggests that newborns delivered by cesarean may benefit from drinking a small amount of their mother's feces dissolved in breast milk, because it provides them with beneficial bacteria they would otherwise be exposed to in vaginal birth. (2020-10-01)
Hackensack Meridian CDI scientists find one-two punch for preclinical cancer models
Research findings published Aug. 14, 2020 in the journal Cancer Research suggest that since some cancer treatments can be undermined by epigenetic changes (altered DNA methylation affecting gene expression) in cancer cells before the treatments are even administered, a worthwhile strategy is to administer an epigenetically-acting drug - which can pave the way for more effective subsequent use of immune-acting cancer treatments. (2020-09-30)
Innate lymphoid cells regenerate within lung
Max Planck researcher Dominic Grün teamed up with colleagues from Würzburg headed by Georg Gasteiger and generated a comprehensive atlas of Innate lymphoid cells (ILCs) of the lung. (2020-09-30)
Scientists propose immune cocktail therapy to boost cancer-immunity cycle in multiple aspects
A research team led by Prof. TIAN Huayu from the Changchun Institute of Applied Chemistry (CIAC) of the Chinese Academy of Sciences proposed an innovative immune cocktail therapy that combined ICT along with other therapeutic approaches. (2020-09-30)
Cells sacrifice themselves to boost immune response to viruses
Whether flu or coronavirus, it can take several days for the body to ramp up an effective response to a viral infection. (2020-09-30)
Common antioxidant enzyme may provide potential treatment for COVID-19
Catalase, a naturally occurring enzyme, holds potential as a low-cost therapeutic drug to treat COVID-19 symptoms and suppress the replication of coronavirus inside the body. (2020-09-29)
Mussels connect antibodies to treat cancer
POSTECH research team develops innovative local anticancer immunotherapy technology using mussel protein. (2020-09-29)
Inflammatory gene provides clue to obesity risk
A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found. (2020-09-29)
Prostate cancer: immunotherapy offers hope
An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasised, castration-resistant prostate cancer. (2020-09-29)
New genetic knowledge on the causes of severe COVID-19
A proportion of the most severe COVID-19 cases can be explained by genetic defects in the patients' immune system. (2020-09-29)
Blocking enzyme's self-destruction process may mitigate age-related diseases
Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology. (2020-09-29)
Memory training for the immune system
The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. (2020-09-28)
Strong activation of anti-bacterial T cells linked to severe COVID-19
A type of anti-bacterial T cells, so-called MAIT cells, are strongly activated in people with moderate to severe COVID-19 disease, according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal Science Immunology. (2020-09-28)
Insect Armageddon: low doses of the insecticide, Imidacloprid, cause blindness in insects
Joint research provides important evidence on the role of insecticides on the longevity of insect population. (2020-09-28)
Uncovering a 'suPAR' culprit behind kidney injury in COVID-19
A new observational study finds patients in the hospital for COVID-19 have high levels of soluble urokinase receptor (suPAR), an immune-derived pathogenic protein that is strongly predictive of kidney injury. (2020-09-24)
Scientists trace severe COVID-19 to faulty genes and an autoimmune condition
An international team led by Jean-Laurent Casanova has led to a breakthrough in understanding why only some people develop severe COVID-19: due to faulty genes or misguided antibodies, they lack type I interferons, proteins vital in protecting against viruses. (2020-09-24)
Study reveals higher COVID-19 mortality in men could be explained by differences in circulating proteins and immune system cells
New research presented at the ESCMID Conference on Coronavirus Diseases (ECCVID, online 23-25 September) suggests that the higher risk of poor COVID-19 outcomes in men could be explained by differences in circulating proteins and immune system cells compared with women. (2020-09-24)
Scientists identify dozens of genes allowing cancer cells to evade the immune system
Cancer immunotherapy can be extremely successful but so far has only worked in a fraction of patients and tumour types. (2020-09-23)
Berry good news -- new compound from blueberries could treat inflammatory disorders
Inflammatory bowel disease (IBD), caused by chronic inflammation in the digestive tract linings, can be debilitating and life threatening. (2020-09-23)
Children's immune response more effective against COVID-19
Children and adults exhibit distinct immune system responses to infection by the virus that causes COVID-19, a finding that helps explain why COVID-19 outcomes tend to be much worse in adults, researchers from Yale and Albert Einstein College of Medicine report Sept. (2020-09-22)
Targeting the treatment of autoimmune diseases
A team of researchers from Charité - Universitätsmedizin Berlin and the Deutsches Rheuma-Forschungszentrum (DRFZ) Berlin, a Leibniz Institute, have successfully treated two patients with the autoimmune disease systemic lupus erythematosus. (2020-09-22)
COVID-19 mortality rates higher among men than women
A new review article from Beth Israel Deaconess Medical Center (BIDMC) shows people who are biologically male are dying from COVID-19 at a higher rate than people who are biologically female. (2020-09-22)
Modeling future COVID-19 cases under a variety of immune responses, and with or without vaccines
Researchers who adapted standard epidemiological models to explore how the COVID-19 pandemic trajectory might unfold in the next five years report diverse scenarios ranging from recurring severe epidemics to elimination. (2020-09-21)
Children with COVID-19 show different immune responses, but better outcomes than adults
A comparison of children and adults hospitalized with COVID-19 reveals pediatric patients, who had better outcomes and shorter hospital stays, displayed altered immune responses and more limited production of antibodies against infection. (2020-09-21)
Researchers find diminished response by 'killer' T cells in elderly COVID-19 patients
Although people of any age can become infected with SARS-CoV-2, the virus that causes COVID-19, elderly patients face a higher risk of severity and death than younger patients. (2020-09-21)
Increasing the effectiveness of cancer treatments: Anti-PD-L1 immunotherapy
Researh teams of Tokyo Medical and Dental University (TMDU) and Harvard Medical School (HMS) have uncovered how to increase the efficacy of anti-PD-L1 immunotherapy. (2020-09-18)
Increasing the effectiveness of immunotherapy against skin cancer
Researchers at the University of Bern have discovered a mechanism in the body's own immune system which is responsible for the maturation and activation of immune cells. (2020-09-18)
Removal of a gene could render lethal poxviruses harmless
The removal of one gene renders poxviruses - a lethal family of viral infections that are known to spread from animals to humans - harmless, a new study in the journal Science Advances reports. (2020-09-18)
Immune system may have another job -- combatting depression
An inflammatory autoimmune response within the central nervous system similar to one linked to neurodegenerative diseases such as multiple sclerosis (MS) has also been found in the spinal fluid of healthy people, according to a new Yale-led study comparing immune system cells in the spinal fluid of MS patients and healthy subjects. (2020-09-18)
Improving the efficacy of cellular therapies
A new study published in Nature Communications deepens the understanding of the development of T cell, an important component of the immune system. (2020-09-17)
Biomarker predicts who will have severe COVID-19
KAIST researchers have identified key markers that could help pinpoint patients who are bound to get a severe reaction to COVID-19 infection. (2020-09-17)
Super-potent blood stem cells discovered in human embryos
In research recently published in Stem Cell Reports, Andrejs Ivanovs, Alexander Medvinsky (a.medvinsky@ed.ac.uk) and colleagues from the University of Edinburgh discovered that HSCs from early human embryos, when HSCs are just starting to form, are more robust at expanding than those from the cord blood. (2020-09-17)
PPIs may affect responses to atezolizumab in patients with urothelial cancer
Proton pump inhibitor (PPI) use was associated with worse outcomes in patients with urothelial cancer treated with the immunotherapeutic atezolizumab (Tecentriq), compared with patients who did not use PPIs. (2020-09-17)
Injectable hydrogel could someday lead to more effective vaccines
Vaccines have curtailed the spread of several infectious diseases, such as smallpox, polio and measles. (2020-09-16)
Stop Livin to make lymphoma cells stop living
Researchers at the University of Tsukuba have shown that the protein Livin, an inhibitor of apoptosis or programmed cell death, mediates resistance to immunotherapy in some lymphoma variants. (2020-09-16)
New targets for melanoma treatment
A collaborative study led by Monash University's Biomedicine Discovery Institute and the Olivia Newton-John Cancer Research Institute (ONJCRI) has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumours and could pave the way for therapeutic vaccines to be developed in the fight against melanoma. (2020-09-16)
Immune 'cloaking' in cancer cells and implications for immunotherapy
Researchers at Queen Mary University of London, The Institute of Cancer Research, London, and the Moffitt Cancer Centre have created a mathematical model that can determine the impact of the immune system on tumour evolution. (2020-09-16)
Discoveries made in how immune system detects hidden intruders
Research led by Dr. Wonmuk Hwang has led to better understanding on how components of the body's immune system find intruding or damaged cells, which could lead to novel approaches to viral and cancer treatments. (2020-09-16)
T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity
A multi-layered, virus-specific immune response is important for controlling SARS-CoV-2 during the acute phase of the infection and reducing COVID-19 disease severity, with the bulk of the evidence pointing to a much bigger role for T cells than antibodies. (2020-09-16)
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