Current Kidney disease News and Events

Current Kidney disease News and Events, Kidney disease News Articles.
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Survival protein may prevent collateral damage during cancer therapy
Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies. The 'cell survival protein', called BCL-XL, was required in laboratory models to keep kidney cells alive and functioning during exposure to chemotherapy or radiotherapy. Kidney damage is a common side effect of these widely used cancer therapies, and the discovery has shed light on how this damage occurs at the molecular level. (2020-11-25)

RASi associated with reduced risk of KRT compared with CCB in CKD patients
In a population-based Swedish database, researchers studied the clinical outcomes of starting renin-angiotensin system inhibitor (RASi) or calcium channel blockers (CCB) in 2,458 patients with CKD G4-5. Compared with CCB, RASi initiation was associated with a lower risk of KRT, but similar risks of mortality and major adverse cardiovascular events. These findings suggest that RASi initiation might slow the progression of kidney disease compared with CCB in patients with advanced CKD, and offer similar cardiovascular protection. (2020-11-24)

Non-invasive electrolyte levels' measuring method can prevent sudden cardiac death
Researchers from Kaunas University of Technology (KTU), Lithuania came up with the idea on how to measure fluctuating blood potassium levels non-invasively, through electrocardiogram. The researchers claim that their method may become a digital biomarker in the future for managing electrolyte levels. This would be a huge step towards preventing potentially life-threatening conditions among people who suffer from chronic kidney disease. (2020-11-23)

Researchers use cutting edge technology to bioprint mini-kidneys
Researchers have used cutting edge technology to bioprint miniature human kidneys in the lab, paving the way for new treatments for kidney failure and possibly lab-grown transplants. (2020-11-23)

Afro-Caribbean patients with severe kidney disease at greater risk of hospitalisation from COVID-19
Afro-Caribbean people with end stage kidney disease (ESKD) are more likely to be hospitalised with COVID-19 than other ethnicities, a study has found. (2020-11-19)

New diabetes medication reduced heart event risk in those with diabetes and kidney disease
Sotagliflozin - a type of medication known as an SGLT2 inhibitor primarily prescribed for Type 2 diabetes - reduces the risk of adverse cardiovascular events for patients with diabetes and kidney disease. Researchers say the results of this randomized clinical trial provide evidence that SGLT2 inhibitors should be part of the standard of care for people with Type 2 diabetes and chronic kidney disease. (2020-11-17)

New medication helps heart health in people with chronic kidney disease, Type 2 diabetes
Results of a large, international clinical trial on the novel medication finerenone indicate it reduced the rate of death, heart attack, stroke and hospitalization for heart failure among patients with chronic kidney disease and Type 2 diabetes. Finerenone helped patients with chronic conditions improve their heart health, regardless of if they had a history of cardiovascular disease. (2020-11-17)

SCORED and SOLOIST trials add to evidence for treating diabetes with SGLT2 inhibitors
In these two paired trials, teams of investigators led by Brigham cardiologist Deepak L. Bhatt, MD, MPH, evaluated sotagliflozin, a drug that inhibits SGLT2 and SGLT1. Results of the trials are both published in The New England Journal of Medicine and presented by Bhatt simultaneously at the Late-Breaking Clinical Trial Sessions of the American Heart Association Scientific Sessions. (2020-11-16)

How to ensure patients manage their chronic kidney disease
A Singapore study finds patients with chronic kidney disease need tailored nutrition guidance, as well as better communication with doctors and family support, to empower them to manage their condition. (2020-11-13)

Rats also capable of transmitting hantavirus
A group of researchers from Charité -- Universitätsmedizin Berlin have confirmed Germany's first-ever case of animal-to-human transmission involving a specific species of virus known as the 'Seoul virus'. Working alongside colleagues from Friedrich-Loeffer-Institut (FLI), the researchers were able to confirm the presence of the virus in a young female patient and her pet rat. (2020-11-12)

UC research finds low rates of contraceptive use in women with kidney failure
New research from the University of Cincinnati finds that women with kidney failure have low rates of contraceptive use. The study, published in the journal Kidney Medicine, finds an overall contraceptive use rate of 5.3% among women with kidney failure undergoing dialysis in the United States. (2020-11-12)

An epidemic outbreak of Mesoamerican Nephropathy in Nicaragua linked to nickel toxicity
For over 20 years, researchers have tried to solve the medical mystery behind Mesoamerican Nephropathy, a form of chronic kidney disease that has caused more than 50,000 deaths in coastal South America. Now, Baylor College of Medicine and Texas Children's Hospital researchers present the strongest evidence to date on the cause of the disease in one of the worst-hit hotspots in the region, Nicaragua, using an unlikely source, the toenails of individuals with the disease. (2020-11-12)

New European consensus on management of osteoporosis in advanced chronic kidney disease
This Consensus is authored by the European Renal Osteodystrophy Working Group, with expertise from the European Renal Association-European Dialysis and Transplant Association and the International Osteoporosis Foundation. It provides a succinct review of current clinical practice, and outlines practical recommendations for diagnosis, assessment of fracture risk, intervention thresholds, non-pharmacological and pharmacological intervention strategies, monitoring, and secondary fracture prevention. (2020-11-11)

Racial/ethnic minorities comprise small portion of patients referred with AL amyloidosis
Despite being theoretically at an increased risk for AL amyloidosis, underrepresented minorities make up only a small percentage of patients seen at specialized treatment centers for this disease. (2020-11-10)

Simultaneous kidney transplant plus weight loss surgery safe for obese patients
A new study shows that robotic-assisted kidney transplant and weight loss surgery can be performed safely. (2020-11-10)

Unhealthy dietary habits are associated with the risk of proteinuria onset
Researchers from Kanazawa University found out that unhealthy dietary habits as a risk factor for proteinuria onset which is a key prognostic factor of chronic kidney disease (CKD). By investigating over 26,000 patients with no prior CKD who underwent annual medical check-ups in Kanazawa between 1998 and 2014, skipping breakfast and late dinner were associated with proteinuria onset. These findings suggest that modification of dietary habits may be a potential treatment for CKD. (2020-11-09)

HCQ has no significant impact on heart rhythm in lupus patients, even those with CKD
New research shows that adults with lupus who take the antimalarial drug, hydroxychloroquine, do not have any differences in their corrected QT (QTc) intervals, an electrocardiogram (EKG) measurement of the heart's electrical signals, even if they have chronic kidney disease (CKD), a complication of lupus that can be associated with increased levels of the medication. (2020-11-06)

Antiangiogenic therapy can cause malignancy in kidney cancers
In some cases, this type of therapy increases the invasiveness and metastasis of kidney tumors. The study led by IDIBELL and the ICO identifies a biomarker that could predict the malignant response of patients to therapy. (2020-11-05)

UL research reveals extreme levels of uric acid can significantly reduce patient survival
Extreme values of serum uric acid levels in the blood can markedly reduce a patient's chance of surviving and reduce their lifespans by up to 11 years, according to a new study by researchers at University of Limerick's School of Medicine in Ireland. (2020-11-04)

Biomarker combination predicts kidney injury in critically ill children
Researchers at the University of Liverpool have identified a unique method of identifying the early signs of a potentially serious condition known as Acute Kidney Injury (AKI). (2020-11-02)

Immunotherapy side effect could be a positive sign for kidney cancer patients
An autoimmune side effect of immune checkpoint inhibitor (ICI) drugs could signal improved control of kidney cancer, according to a new study by researchers in UT Southwestern's Kidney Cancer Program (KCP). (2020-11-02)

Intensive urate lowering reduces urine albumin excretion
Phase 2 trial of verinurad with febuxostat vs. placebo shows 49% reduction in albuminuria (2020-10-29)

Cell-Free DNA provides a dynamic window into health
A new study presented at the ASHG 2020 Virtual Meeting shows how cfDNA testing can be used to provide insight into a patient's health. (2020-10-26)

Study reveals details behind transplant disparities experienced by black patients
In an analysis of information on patients with kidney failure, Black patients are less likely than white patients to be placed on transplant waiting lists. For patients on such lists, Blacks are less likely to receive transplants than whites. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-25)

The effects of social determinants of health on kidney transplant candidates
Social determinants of health are associated with patient-reported outcomes in adults who are eligible to undergo kidney transplantation evaluations. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-25)

Model predicts acute kidney injury requiring dialysis in patients with COVID-19
In a recent study, a new algorithm achieved good performance for predicting which hospitalized patients will develop acute kidney injury requiring dialysis. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-24)

New model predicts which patients with kidney disease may develop heartbeat irregularities
* A new model that incorporates a type of artificial intelligence can accurately predict which individuals with chronic kidney disease face a high risk of developing atrial fibrillation. * Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-24)

Clinical trial shows experimental drug safely slows progression of diabetic kidney disease
Patients with diabetic kidney disease can potentially be treated with a new investigational medication that may slow the progress of their illness without harmful side effects to their hearts, according to the results of a global clinical trial announced Friday. (2020-10-23)

Research team discovers molecular processes in kidney cells that attract and feed COVID-19
What about the kidneys make them a hotspot for COVID-19's cytokine storm? A research team says it's the presence of a protein found on specialized renal transport cells. (2020-10-23)

Molecular processes in kidney cells may 'prime' diabetics for COVID-19 infection
People with diabetes -- especially those with diabetic kidney disease -- are among the most at risk for COVID-19. A new study peered inside the kidney cells of COVID-19 patients and diabetic kidney disease patients and made a surprising discovery: Similar molecular processes were activated in both sets of patients. The results suggest that diabetes may predispose patients to SARS-CoV-2 infection or more severe COVID-19 by spurring biological processes used by the virus to infect and replicate. (2020-10-23)

New algorithm predicts likelihood of acute kidney injury
In a recent study, a new algorithm outperformed the standard method for predicting which hospitalized patients will develop acute kidney injury. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-23)

'Patient activation' may improve quality of life in individuals with kidney disease
In individuals with chronic kidney disease who received online peer mentoring, improved patient activation correlated with improvements in various aspects of quality of life. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-23)

Acute kidney injury among African Americans with sickle cell trait and disease
New research examines the risk of acute kidney injury in people with sickle cell trait or disease, as well as the effect of acute kidney injury on kidney function decline in these individuals. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-23)

Why do minorities have higher rates of kidney failure?
A new study indicates that Blacks and Hispanics have experienced higher rates of kidney failure compared with whites due to more rapid kidney function decline. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-23)

Glomerular diseases linked to higher risk of cardiovascular conditions
Adults with glomerular diseases have a 2.5-times higher risk of developing cardiovascular disease than individuals in the general population. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-22)

Questionnaire-based tool measures fatigue in patients receiving dialysis
A new patient-reported outcome measure assesses fatigue in patients receiving dialysis. The tool gauges tiredness, energy, and the impact of fatigue on life participation. (2020-10-22)

Serum creatinine-to- cystatin C ratio predicts mortality
In patients initiating continuous renal replacement therapy for acute kidney injury, higher serum creatinine-to-cystatin C ratios were associated with lower mortality. (2020-10-21)

Aging alone does not explain kidney pathology
Histopathology in non-neoplastic kidney tissue from 1,347 nephrectomy specimens showed very limited histopathologic changes in subset of older individuals. (2020-10-21)

Children with chronic kidney disease have outsized health burden
Chronically ill children with kidney disease may spend more time in the hospital, incur larger health care costs and have a higher risk of death compared to pediatric patients hospitalized for other chronic conditions, a new study suggests. (2020-10-20)

Vitamin D: Consumption of high-dose food supplements is unnecessary
The German Federal Institute for Risk Assessment (BfR) has prepared a health risk assessment for products sold on the market as food supplements containing a daily dose of chole-calciferol -- the precursor to active vitamin D -- of 50 or 100 micrograms. These products are representative of certain high-dose preparations used by some consumers to increase their intake of vitamin D. (2020-10-20)

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