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Current Kidney transplant News and Events

Current Kidney transplant News and Events, Kidney transplant News Articles.
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Human lungs rejected for transplant recovered using novel technique
A multidisciplinary team from Vanderbilt University Medical Center (VUMC) and Columbia University has demonstrated that injured human donor lungs declined for transplant can be recovered by cross-circulation between the human lung and a xenogeneic host. (2020-07-13)
COVID-19 in patients who have received kidney transplants or are undergoing dialysis
A recent study found that most kidney transplant recipients with COVID-19 do not need to be hospitalized. (2020-07-07)
Diabetic nephropathy: Study results on proteomic analysis do not show benefit
First study on a treatment strategy using a proteomic analysis does not clarify which therapeutic consequence of the test could offer a benefit for people with diabetes and high blood pressure. (2020-07-06)
Children's National Hospital quality initiative changes culture of antibiotic prescribing in NICU
A quality improvement initiative in the Neonatal Intensive Care Unit (NICU) at Children's National Hospital led to a significant reduction in treatment with intravenous vancomycin, an antibiotic used for resistant gram positive infections, which is often associated with acute kidney injury. (2020-07-01)
First successful delivery of mitochondria to liver cells in animals
This experiment marks the first time researchers have ever successfully introduced mitochondria into specific cells in living animals. (2020-06-25)
University of Minnesota Medical School finds promising treatment to slow kidney disease doesn't prove out in clinical trial
A new study from the University of Minnesota Medical School found that allopurinol, an inexpensive generic drug that reduces uric acid levels, did not show benefits in protecting from loss of filtering function in the kidney. (2020-06-25)
Promising treatment to slow kidney disease doesn't prove out in clinical trial
Progression of kidney disease in type 1 diabetes is correlated with increased amounts of uric acid. (2020-06-25)
Drug used to slow kidney disease found to be ineffective
In a major clinical trial, clinicians have found the drug allopurinol does not prevent worsening of kidney disease, despite up to 20 per cent of kidney disease patients being prescribed the medication. (2020-06-24)
Females use anti-inflammatory T cells to keep their blood pressure down
In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say. (2020-06-23)
Biomarker test highly accurate in detecting early kidney cancer
A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists, say scientists from Dana-Farber Cancer Institute. (2020-06-22)
Study finds HCV-positive livers safe for transplantation; Patients cured afterward
UC researchers find similar results for positive outcomes when comparing patients receiving livers infected with hepatitis C to patients who receive livers without infection. (2020-06-22)
Mortality rates higher following kidney injury, University of Cincinnati research finds
New research from the University of Cincinnati shows kidney failure resulting from acute kidney injury leads to a higher risk of death in the first six months compared to kidney failure from diabetes or other causes. (2020-06-19)
Antioxidant agent may prevent chronic kidney disease and Parkinson's disease
Researchers from Osaka University developed a novel dietary silicon-based antioxidant agent with renoprotective and neuroprotective effects. (2020-06-18)
Researchers identify key steps in development of kidneys
The discovery of how certain key structures in the kidneys are formed could have important implications for treating renal fibrosis (or scarring), a feature of chronic kidney disease (CKD). (2020-06-18)
Liver perfusion could save 7 in 10 rejected donor livers
A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment. (2020-06-17)
Call for caution for using a CAR-T immunotherapy against acute myeloid leukemia
Researchers from the Josep Carreras Leukaemia Research Institute prove that the preclinical implementation of Acute Myeloid Leukaemia immunotherapy, based on CD123-redirected CAR T-cells, affects hematopoiesis, blood cells production, and reconstitution. (2020-06-17)
Diabetic mice improve with retrievable millimeter-thick cell-laden hydrogel fiber
Researchers from The University of Tokyo developed a novel fiber-shaped hydrogel transplant for the treatment of type 1 diabetes mellitus. (2020-06-15)
More and safer heart transplants could become possible with new heart box
A donated heart can now be transported and preserved for longer than what has previously been possible. (2020-06-15)
Fewer complications after organ transplantation
A large international study coordinated by University Hospital Regensburg and Charité - Universitätsmedizin Berlin has demonstrated the safety of new cell therapy approaches for use in kidney transplant recipients. (2020-06-10)
Kidneys deteriorate with age, regardless of health
Why we age remains an unanswered question. But recently, researchers at UiT, along with colleagues in Berlin and Reykjavik, have discovered that kidneys age, regardless if people are sick or not. (2020-06-09)
Racial, gender disparities observed in heart transplant recipients with COVID-19 infection
Researchers suggest focusing on disparities to help identify which patients with a heart transplant may be at higher risk for a worse course of COVID-19 infection. (2020-06-09)
Cryoablation comparable to surgery for treating early-stage kidney cancer
A minimally invasive procedure that destroys cancer cells by freezing them is as effective as surgery for treating early-stage kidney cancer, offering similar 10-year survival rates with a lower rate of complications, according to a new study. (2020-06-09)
Predictors of 5-year mortality in young dialysis patients
The analysis published in NDT [1] evaluated for the first time the association of a large number of demographic, HD treatment and laboratory variables with mortality in patients on chronic hemodialysis treatment since childhood. (2020-06-09)
Use of cystatin C for precise assessment of kidney function and cardiovascular risk
In many situations, it is essential that the physician knows a patient's kidney function as precisely as possible. (2020-06-09)
Fecal transplants show promise as treatment for non-alcoholic fatty liver disease
A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease (NAFLD). (2020-06-09)
Acute kidney disease in critically ill COVID-19 patients
A current study [1] is the first to evaluate and characterize the occurrence of COVID-19-associated acute kidney injury (AKI) in a larger number of critically ill patients. (2020-06-08)
Specific kidney proximal tubular injury caused by SARS-CoV-2
A French study [1] investigated acute Fanconi syndrome as a kidney injury associated with COVID-19. (2020-06-08)
Indirect effects of SARS-CoV-2 on the kidneys: beware of the genetic background
A current study [1] reports on two COVID-19 patients with acute kidney injury. (2020-06-08)
Hope for patients with primary hyperoxaluria type 1
Lumasiran is a subcutaneously administered RNAi therapeutic targeting hydroxyacid oxidase 1 (HAO1) - the gene encoding glycolate oxidase (GO) - in development for the treatment of primary hyperoxaluria type 1 (PH1). (2020-06-07)
Empagliflozin -- kidney protection regardless of an initial 'eGFR dip'
Data presented today at the ERA-EDTA Congress show that empagliflozin is more likely to induce an initial 'dip' in eGFR in patients belonging to a higher KDIGO risk category and/or on diuretic therapy. (2020-06-07)
Protecting the kidneys from failing
Researchers from the University of Tsukuba identified the protein MafB as a key molecular actor in the development of FSGS. (2020-06-05)
Are kidney transplant patients at higher risk? The European experience
The risk of death is relatively high in kidney transplant patients admitted to hospital with COVID-19. (2020-06-05)
COVID-19 mortality alarmingly high in dialysis patients
Analysis of a Spanish experience shows that COVID-19 is frequent in hemodialysis patients, who appear to be at risk for worse outcome. (2020-06-05)
Acute kidney injury and end stage kidney disease in severe COVID-19
Many COVID-19 patients experience hematuria, proteinuria and elevated serum creatinine concentration early in the course of the disease. (2020-06-05)
Cord blood for stem cell transplant may outperform matched sibling donor
Study based on a decade of research and treatment shows no difference in overall survival between cord blood and matched related donor as source for stem cell transplant, with reduced graft-versus-host disease in patients using cord blood. (2020-06-05)
UT Health San Antonio study shows Nox4 protein may predict untreatable kidney cancer
University of Texas Health Science Center at San Antonio researchers confirmed the role of a certain protein, Nox4, in the development of high-grade kidney cancer. (2020-06-03)
Lab-grown miniature human livers successfully transplanted in rats
Using skin cells from human volunteers, researchers at the University of Pittsburgh School of Medicine have created fully functional mini livers, which they then transplanted into rats. (2020-06-02)
Study reveals factors influencing outcomes in kidney cancer treated with immunotherapy
By analyzing tumors from patients treated with immunotherapy for advanced kidney cancer in three clinical trials, Dana-Farber Cancer Institute scientists have identified several features of the tumors that influence their response to immune checkpoint inhibitor drugs. (2020-05-29)
Unique 'home built' device provides fast disease analysis in kidneys affected by diabetes
The amount of scarring in damaged kidneys as a result of diabetes or acute injury, is a key factor in determining treatment. (2020-05-28)
Device simulates filtering and ion transport functions of human kidney
University of Arkansas researchers have developed a device that simulates the blood filtering and ion transport functions of the human kidney. (2020-05-27)
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