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Current Leukemia News and Events

Current Leukemia News and Events, Leukemia News Articles.
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Research paves way for new source for leukemia drug
Chemistry researchers have patented a method for making anti-leukemia compounds that until now have only been available via an Asian tree that produces them. (2019-03-20)
Epigenetic protein could be new therapeutic target in acute myeloid leukemia
British researchers have discovered that an epigenetic protein called EZH2 delays the development of acute myeloid leukemia (AML) but then switches sides once the disease is established to help maintain tumor growth. (2019-03-19)
Genetically encoded sensor isolates hidden leukemic stem cells
Tel Aviv University researchers have devised a novel biosensor that can isolate and target leukemic stem cells. (2019-03-12)
Starving leukemia cells by targeting amino acids
Eliminating ASCT2 selectively stops the growth of leukemia cells, while having limited effects on healthy blood cells and hematopoetic (blood-forming) stem cells. (2019-03-12)
Atlas of acute myeloid leukemia cell types may lead to improved, targeted therapies
A research team led by Massachusetts General Hospital investigators has assembled a detailed atlas of bone marrow cells from patients with acute myeloid leukemia, an aggressive blood cancer that usually leads to death within five years of diagnosis. (2019-02-28)
Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children
Progress reported on understanding why Hispanic children are more likely to develop acute lymphoblastic leukemia and to die of the disease. (2019-02-14)
New therapy for aggressive blood cancer discovered
Researchers at Vetmeduni Vienna and Ludwig Boltzmann Institute for Cancer Research have identified a new therapeutic strategy for Acute Myeloid Leukemia. (2019-02-13)
Financial relationships and prescribing practices between physicians and drug companies
In a study published in The Oncologist, physicians treating certain cancers who consistently received payments from a cancer drug's manufacturer were more likely to prescribe that drug over alternative treatments. (2019-02-06)
Cancer causes premature ageing
New research shows that cancer causes premature ageing. Researchers studied Leukaemia, and found that it promotes premature ageing in healthy bone marrow cells. (2019-01-30)
Finding second hits to knock out leukemia
Targeted drugs are a cornerstone of personalized medicine, yet come with important drawbacks. (2019-01-28)
Drug compound could be next-generation treatment for aggressive form of leukemia
Purdue University researchers are developing a series of drug compounds that have shown promise in treating acute myeloid leukemia, an aggressive blood cancer that is one of the most lethal cancers. (2019-01-28)
Understanding the emergence of leukemia
Acute T-cell lymphoblastic leukemia is a rare type of blood cancer that affects mostly children. (2019-01-25)
New treatment approach for leukemia
An international research team led by researchers from Vetmeduni Vienna have made an important discovery that could lead to a better understanding of lymphocytic leukemia. (2019-01-24)
Cancer has a biological clock and this drug may keep it from ticking
Scientists at USC Michelson Center and Japan's Nagoya University find and test a promising drug that stops cancer by interfering with the cancer cells' metabolism and other circadian-related functions. (2019-01-23)
No substantial benefit from transplantation reported for a high-risk leukemia subtype
Study led by St. Jude Children's Research Hospital found treatment guided by measuring minimal residual disease was associated with better outcomes for hypodiploid acute lymphoblastic leukemia patients. (2019-01-18)
Killer blows? Knockout study of pair of mouse MicroRNA provides cancer insight
Tokyo Medical and Dental University (TMDU) researchers used knockout mouse models created by gene editing to reveal that the miRNA miR-146b, like miR-146a, is involved in the development of cancers, with them having similar but not identical effects. (2019-01-17)
More accurate leukemia diagnosis expected as researchers refine leukemia classification
Research led by St. Jude Children's Research Hospital means more than 90 percent of the most common cases of childhood cancer can now be classified by subtype, an advance likely to fuel precision medicine. (2019-01-14)
New leukemia drug is more effective and easier to use
A landmark study co-authored by a Loyola Medicine oncologist has found that a newer targeted drug is significantly more effective than standard therapy for treating elderly patients with chronic lymphocytic leukemia (CLL). (2019-01-11)
An errant editing enzyme promotes tumor suppressor loss and leukemia propagation
UC San Diego researchers have found a stem cell enzyme copy edits more than 20 tumor types, providing new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation. (2019-01-03)
Pediatric leukemia 'super drug' could be developed in the coming years
Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, according to three studies published over the last two years in the journal Cell, and the final paper published Dec. (2018-12-21)
Study finds elevated risk of rare blood cancers after chemotherapy for most solid tumors
Findings from a new study by researchers at the National Cancer Institute (NCI) show that patients treated with chemotherapy for most solid tumors during 2000-2014 experienced an increased risk of therapy-related myelodysplastic syndrome/acute myeloid leukemia (tMDS/AML). (2018-12-20)
NSU researchers uncover genetic marker, predictor of early relapse in pediatric ALL
Researchers recently discovered that by testing the level of NER (nucleotide excision repair) gene expression, pediatric oncologists can determine the likelihood of early relapse (less than three years) in their acute lymphoblastic leukemia (ALL) patients. (2018-12-13)
Syracuse physicist creates tiny sensors to assist in cancer detection
A Syracuse University physicist hopes to improve cancer detection with a new and novel class of nanomaterials. (2018-12-10)
Potential seen for tailoring treatment for acute myeloid leukemia
Rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia. (2018-12-07)
Ibrutinib plus rituximab superior to standard treatment for patients with chronic leukemia
The results of the E1912 phase 3 clinical trial show that the novel treatment of ibrutinib and rituximab is superior to the historical best treatment, which is chemotherapy. (2018-12-04)
Immunotherapy pioneers reveal updated efficacy data of tisagenlecleucel CAR T-cell therapy
Physician-scientists from Children's Hospital of Philadelphia presented updated efficacy and safety data on Kymriah (tisagenlecleucel, formerly CTL019) -- the first-ever FDA-approved personalized CAR T-cell gene immunotherapy for aggressive blood cancers, at the 60th American Society of Hematology annual meeting, as well as first-of-its-kind research on overcoming CAR T-cell resistance. (2018-12-04)
Dana-Farber to present new research on stem cell transplantation for myeloid cancers
Improving outcomes for patients with myeloid cancers who undergo stem cell transplantation is a focus of several studies to be presented by Dana-Farber Cancer Institute scientists at the ASH Annual Meeting. (2018-12-03)
Mayo Clinic researchers identify new strategies that may improve CAR-T cell therapy
Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy (CAR-T cell therapy) in treating cancer. (2018-12-03)
Cleveland Clinic's Aziz Nazha, M.D., develops personalized prediction model for patients with MDS
At the American Society of Hematology (ASH) Annual Meeting, Cleveland Clinic medical hematologist and oncologist Aziz Nazha, M.D., will present results of a personalized prediction model that surpassed current prediction models for Myelodysplastic Syndromes (MDS). (2018-12-02)
Dana-Farber researchers report clinical trial results in treatment of leukemia & lymphoma
New results from clinical trials of immunotherapy and experimental targeted agents for patients with leukemia and lymphoma are being presented by Dana-Farber Cancer Institute researchers at the ASH Annual Meeting. (2018-12-02)
Experts present new recommendations on 'overlapping' type of leukemia
Chronic myelomonocytic leukemia (CMML) is a rare disease with overlapping features of two categories of bone marrow and blood cell disorders that poses challenges in clinical management. (2018-11-30)
Inconspicuous protein key to deadly blood cancer
Mixed lineage leukemia (MLL) is a very aggressive blood cancer, capable of causing the growth of cancerous cells in numerous ways. (2018-11-29)
Venetoclax combination approved for elderly AML
Older patients with acute myeloid leukemia (AML) often aren't healthy enough to receive intensive chemotherapy, and gentler treatments aren't very effective in treating this aggressive blood cancer. (2018-11-29)
Healthy blood stem cells have as many DNA mutations as leukemic cells
Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. (2018-11-28)
New stem-cell therapy to improve fight against leukemia
Stem-cell transplantation is an effective form of therapy to fight leukemia. (2018-11-28)
91 percent response rate for venetoclax against newly diagnosed AML in older adults
Clinical trial results published in the journal Nature Medicine and being presented this weekend at the American Society for Hematology Annual Meeting show 91 percent response rate to the combination of venetoclax with azacitidine in older adults newly diagnosed with acute myeloid leukemia (AML). (2018-11-28)
Leukemia epigenetics in focus
Some severe forms of leukemia develop because proteins on the epigenetic level lose their regulative function. (2018-11-22)
Investigational drug shows promising results in Phase II study of aggressive, often fatal blood disorder with no approved therapies
A Phase I/II study, led by investigators at The University of Texas MD Anderson Cancer Center, reports an investigational drug called tagraxofusp has demonstrated high response rates in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare but highly aggressive -- and often fatal bone marrow and blood disorder -- for which there are no existing approved therapies. (2018-11-14)
Immunotherapy combination and chemotherapy show encouraging results in Phase II acute myeloid leukemia study
A triple therapy combining two immune checkpoint inhibitors (ICPIs) with the standard-of-care chemotherapy, a hypomethylating agent called azacitidine, has shown promising results for treatment of relapsed or refractory acute myeloid leukemia (AML), according to findings from a Phase II study at The University of Texas MD Anderson Cancer Center. (2018-11-13)
Solving the mystery of NPM1 in acute myeloid leukemia
Acute myeloid leukemia (AML) cells expressing the NPM1 mutant gene are highly dependent on continued export of protein NPM1c to proliferate. (2018-11-13)
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