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Current Leukemia News and Events

Current Leukemia News and Events, Leukemia News Articles.
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A heart failure drug to treat leukemia: A promising new therapeutic approach
Researchers followed their intuition that a drug initially intended for heart failure could be effective in treating cancer. (2019-06-12)
SIRT1 plays key role in chronic myeloid leukemia to aid persistence of leukemic stem cells
Patients with chronic myeloid leukemia are treated with tyrosine kinase inhibitors. (2019-06-10)
New research paves the way for safer leukemia treatments
Researchers have discovered a new, safer way to treat a type of childhood leukaemia: T-cell acute lymphoblastic leukemia (T-ALL). (2019-05-30)
Recovery twice as hard for survivors of childhood acute lymphoblastic leukemia
The cardiorespiratory fitness of survivors of childhood acute lymphoblastic leukemia is 22% worse than that general Canadian population,and genetics might play a role, an UdeM researcher finds. (2019-05-29)
Towards a safer treatment for leukemia
An international team of researchers at VIB-KU Leuven, Belgium, the UK Dementia Institute and the Children's Cancer Institute, Australia, have found a safer treatment for a specific type of leukemia. (2019-05-29)
Study reports ibrutinib and venetoclax combo effective as front-line therapy for select chronic lymphocytic leukemia patients
Ibrutinib and venetoclax, two FDA-approved drugs for treating chronic lymphocytic leukemia (CLL), have been shown to be effective when given together for high-risk and older patients with the disease, according to a study at The University of Texas MD Anderson Cancer Center. (2019-05-29)
Tip sheet: Recent research on how DNA is read and copied
Two scientists at the Johns Hopkins University School of Medicine have unraveled aspects of how DNA organizes and preserves genetic information. (2019-05-22)
Researchers pinpoint why lymphoma patients may become resistant to specific therapy
Researchers from Moffitt Cancer Center and Dana-Farber Cancer Institute have discovered a mechanism of drug resistance to Venetoclax®, also known as ABT-199, a BCL-2 targeting drug commonly used to treat chronic lymphocytic leukemia and acute myeloid leukemia. (2019-05-15)
Diabetes linked to numerous cancers in large Chinese study
A new Journal of Diabetes study from China, which has the highest number of people with diabetes among all countries, found that type 2 diabetes was linked with an elevated risk of 11 types of cancer in men and 13 types of cancer in women. (2019-05-09)
New cancer therapy target found in mitochondria for potential treatment of blood cancers
A study at The University of Texas MD Anderson Cancer Center identified a new therapeutic target in cancer cells and explains how new anti-cancer drugs called imipridones work by inducing cancer cell death in blood cancers, such as acute myeloid leukemia (AML) and mantle cell lymphoma. (2019-05-02)
Two birds, one stone: Drug combo may prove effective against second type of leukemia
Researchers tested to see if arsenic trioxide (ATO) was effective in combination with all-trans retinoic acid (ATRA) in in both the mouse model of acute myeloid leukemia (AML) and in human AML cells in the lab, and determined that the combination proved 'powerfully and exquisitely effective' against a subset of AML. (2019-04-25)
Targeted therapy proves effective against aggressive rare blood cancer
Clinical study treating BPDCN with tagraxofusp led to first FDA approval for the disease. (2019-04-24)
Study of tagraxofusp reports 90% response rate for deadly blood cancer with no prior available therapies
An open-label, multi-cohort Phase II trial, led by investigators at the University of Texas MD Anderson Cancer Center, reports that treatment with the drug tagraxofusp resulted in high response rates in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare but highly aggressive -- and often fatal bone marrow and blood disorder -- for which there are no existing approved therapies. (2019-04-24)
Overlooked molecular machine in cell nucleus may hold key to treating aggressive leukemia
Many people fighting a very aggressive form of acute myeloid leukemia (AML) don't survive more than five years. (2019-04-22)
The Leukemia Atlas: researchers unveil proteins that signal disease
Only about one in four people diagnosed with acute myelogenous leukemia (AML) survive five years after the initial diagnosis. (2019-04-17)
Probing the mystery of drug resistance: New hope for leukemia's toughest cases
Alejandro Gutierrez, MD, a researcher at the Dana-Farber/Boston Children's Cancer and Blood Disorders Center has made it his mission to figure out why leukemia treatments cure some patients but not others. (2019-04-16)
New hope for treating childhood brain cancer
Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. (2019-04-04)
A step toward recovering reproduction in girls who survive childhood cancer
Leukemia treatments often leave girls infertile, but a procedure developed by researchers at the University of Michigan working with mice is a step toward restoring their ability to be biological mothers. (2019-04-03)
Targeted drug for leukemia tested at Penn Medicine helps patients live longer
An inhibitor drug that targets a specific mutation in relapsed or refractory acute myeloid leukemia (AML) helps patients live almost twice as long as those who receive chemotherapy. (2019-04-01)
Genomic analysis offers roadmap for diagnosis and treatment of a high-risk leukemia
Acute erythroid leukemia (AEL) is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. (2019-03-29)
How 'sleeper cell' cancer stem cells are maintained in chronic myelogenous leukemia
Even when chronic myelogenous leukemia is in remission, 'sleeper cell,' quiescent leukemic stem cells are maintained in microenvironments in the bone marrow. (2019-03-21)
Research paves way for new source for leukemia drug
Chemistry researchers have patented a method for making anti-leukemia compounds that until now have only been available via an Asian tree that produces them. (2019-03-20)
Epigenetic protein could be new therapeutic target in acute myeloid leukemia
British researchers have discovered that an epigenetic protein called EZH2 delays the development of acute myeloid leukemia (AML) but then switches sides once the disease is established to help maintain tumor growth. (2019-03-19)
Genetically encoded sensor isolates hidden leukemic stem cells
Tel Aviv University researchers have devised a novel biosensor that can isolate and target leukemic stem cells. (2019-03-12)
Starving leukemia cells by targeting amino acids
Eliminating ASCT2 selectively stops the growth of leukemia cells, while having limited effects on healthy blood cells and hematopoetic (blood-forming) stem cells. (2019-03-12)
Atlas of acute myeloid leukemia cell types may lead to improved, targeted therapies
A research team led by Massachusetts General Hospital investigators has assembled a detailed atlas of bone marrow cells from patients with acute myeloid leukemia, an aggressive blood cancer that usually leads to death within five years of diagnosis. (2019-02-28)
Genetic variations in a fourth gene linked to elevated leukemia risk in Hispanic children
Progress reported on understanding why Hispanic children are more likely to develop acute lymphoblastic leukemia and to die of the disease. (2019-02-14)
New therapy for aggressive blood cancer discovered
Researchers at Vetmeduni Vienna and Ludwig Boltzmann Institute for Cancer Research have identified a new therapeutic strategy for Acute Myeloid Leukemia. (2019-02-13)
Financial relationships and prescribing practices between physicians and drug companies
In a study published in The Oncologist, physicians treating certain cancers who consistently received payments from a cancer drug's manufacturer were more likely to prescribe that drug over alternative treatments. (2019-02-06)
Cancer causes premature ageing
New research shows that cancer causes premature ageing. Researchers studied Leukaemia, and found that it promotes premature ageing in healthy bone marrow cells. (2019-01-30)
Finding second hits to knock out leukemia
Targeted drugs are a cornerstone of personalized medicine, yet come with important drawbacks. (2019-01-28)
Drug compound could be next-generation treatment for aggressive form of leukemia
Purdue University researchers are developing a series of drug compounds that have shown promise in treating acute myeloid leukemia, an aggressive blood cancer that is one of the most lethal cancers. (2019-01-28)
Understanding the emergence of leukemia
Acute T-cell lymphoblastic leukemia is a rare type of blood cancer that affects mostly children. (2019-01-25)
New treatment approach for leukemia
An international research team led by researchers from Vetmeduni Vienna have made an important discovery that could lead to a better understanding of lymphocytic leukemia. (2019-01-24)
Cancer has a biological clock and this drug may keep it from ticking
Scientists at USC Michelson Center and Japan's Nagoya University find and test a promising drug that stops cancer by interfering with the cancer cells' metabolism and other circadian-related functions. (2019-01-23)
No substantial benefit from transplantation reported for a high-risk leukemia subtype
Study led by St. Jude Children's Research Hospital found treatment guided by measuring minimal residual disease was associated with better outcomes for hypodiploid acute lymphoblastic leukemia patients. (2019-01-18)
Killer blows? Knockout study of pair of mouse MicroRNA provides cancer insight
Tokyo Medical and Dental University (TMDU) researchers used knockout mouse models created by gene editing to reveal that the miRNA miR-146b, like miR-146a, is involved in the development of cancers, with them having similar but not identical effects. (2019-01-17)
More accurate leukemia diagnosis expected as researchers refine leukemia classification
Research led by St. Jude Children's Research Hospital means more than 90 percent of the most common cases of childhood cancer can now be classified by subtype, an advance likely to fuel precision medicine. (2019-01-14)
New leukemia drug is more effective and easier to use
A landmark study co-authored by a Loyola Medicine oncologist has found that a newer targeted drug is significantly more effective than standard therapy for treating elderly patients with chronic lymphocytic leukemia (CLL). (2019-01-11)
An errant editing enzyme promotes tumor suppressor loss and leukemia propagation
UC San Diego researchers have found a stem cell enzyme copy edits more than 20 tumor types, providing new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation. (2019-01-03)
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