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Current Leukemia News and Events

Current Leukemia News and Events, Leukemia News Articles.
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Leukemia drug shows promise for treating a childhood brain cancer
Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer. (2019-09-20)
Infant with deadly leukemia saved by drug for adult liver cancer
Doctors at UCSF Benioff Children's Hospitals have successfully treated an infant with a rare childhood leukemia using a targeted therapy approved for adults with inoperable liver cancer and advanced kidney cancer. (2019-09-11)
NIH, Cincinnati Children's scientists develop possible strategy for cancer drug resistance
NCATS and Cincinnati Children's Hospital Medical Center scientists have devised a potential treatment against leukemia that could have implications for other cancers. (2019-09-04)
Explaining why TP53 is commonly mutated in human cancer, and the effects of its mutation
A comprehensive functional analysis of TP53 mutations in human leukemia may refute a working hypothesis -- primarily based on mouse studies -- that missense mutations confer new cancer-causing functions to the p53 tumor suppressor protein; the new study instead suggests that these mutations exert a 'dominant-negative' effect that reduces the cancer-suppressing activity of wild-type p53, the authors say. (2019-08-08)
Having a parent, sibling, or child with blood cancer increases one's own risk
New data suggest that people who have a parent, sibling, or child with blood cancer have a higher likelihood of being diagnosed with the disease. (2019-08-08)
Combination targeted therapy may offer hope to infants with a deadly type of leukemia
City of Hope researchers have identified a potential combination targeted therapy for a deadly type of leukemia found in some infants, a population too young to receive full-blown chemotherapy. (2019-08-07)
Old cells, new tricks -- important clue to AML diagnosis and cure discovered
Around 22,000 people will be diagnosed this year in the US with acute myeloid leukemia (AML), the second most common type of leukemia diagnosed in adults and children. (2019-08-01)
The drug combination effective against bovine leukemia
Scientists have succeeded in reducing levels of the bovine leukemia virus (BLV) in cows with severe infections by combining an immune checkpoint inhibitor and an enzyme inhibitor. (2019-08-01)
Drug combo heralds major shift in chronic lymphocytic leukemia treatment
A combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and alive longer than the current standard of care, according to a phase-3 clinical trial of more than 500 participants conducted at Stanford Medicine and multiple other institutions. (2019-07-31)
Researchers discover therapy to treat drug-resistant acute lymphoblastic leukemia
Researchers from Case Western Reserve University School of Medicine have developed a new combination treatment regimen that enhances the immune system's ability to kill leukemias that do not respond to standard treatments. (2019-07-29)
Researchers unveil experimental compound to block therapeutic target in blood cancer
UNC Lineberger Comprehensive Cancer Center researchers have discovered a hyperactive cell signal that contributes to tumor growth in primary effusion lymphoma, an aggressive type of non-Hodgkin lymphoma caused by infection with the Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). (2019-07-22)
Many of the deadliest cancers receive the least amount of research funding
Many of the deadliest or most common cancers get the least amount of nonprofit research funding, reports a new Northwestern Medicine study. (2019-07-18)
Making cancer stem cells visible to the immune system
Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. (2019-07-17)
Reversing t cells' misunderstood rep in responding to a pediatric leukemia
A study of pediatric patients with leukemia demonstrates that they were able to generate T cells against tumor-associated mutations, contradicting previous assumptions that T cells cannot be effectively unleashed on pediatric tumors. (2019-06-26)
Tool dearches EHR data to find child leukemia patients for clinical studies
Researchers who analyzed data in the electronic health records of children seen by hematology/oncology specialists at three large medical centers have developed an algorithm to accurately identify appropriate pediatric oncology patients for future clinical studies. (2019-06-26)
A heart failure drug to treat leukemia: A promising new therapeutic approach
Researchers followed their intuition that a drug initially intended for heart failure could be effective in treating cancer. (2019-06-12)
SIRT1 plays key role in chronic myeloid leukemia to aid persistence of leukemic stem cells
Patients with chronic myeloid leukemia are treated with tyrosine kinase inhibitors. (2019-06-10)
New research paves the way for safer leukemia treatments
Researchers have discovered a new, safer way to treat a type of childhood leukaemia: T-cell acute lymphoblastic leukemia (T-ALL). (2019-05-30)
Recovery twice as hard for survivors of childhood acute lymphoblastic leukemia
The cardiorespiratory fitness of survivors of childhood acute lymphoblastic leukemia is 22% worse than that general Canadian population,and genetics might play a role, an UdeM researcher finds. (2019-05-29)
Towards a safer treatment for leukemia
An international team of researchers at VIB-KU Leuven, Belgium, the UK Dementia Institute and the Children's Cancer Institute, Australia, have found a safer treatment for a specific type of leukemia. (2019-05-29)
Study reports ibrutinib and venetoclax combo effective as front-line therapy for select chronic lymphocytic leukemia patients
Ibrutinib and venetoclax, two FDA-approved drugs for treating chronic lymphocytic leukemia (CLL), have been shown to be effective when given together for high-risk and older patients with the disease, according to a study at The University of Texas MD Anderson Cancer Center. (2019-05-29)
Tip sheet: Recent research on how DNA is read and copied
Two scientists at the Johns Hopkins University School of Medicine have unraveled aspects of how DNA organizes and preserves genetic information. (2019-05-22)
Researchers pinpoint why lymphoma patients may become resistant to specific therapy
Researchers from Moffitt Cancer Center and Dana-Farber Cancer Institute have discovered a mechanism of drug resistance to Venetoclax®, also known as ABT-199, a BCL-2 targeting drug commonly used to treat chronic lymphocytic leukemia and acute myeloid leukemia. (2019-05-15)
Diabetes linked to numerous cancers in large Chinese study
A new Journal of Diabetes study from China, which has the highest number of people with diabetes among all countries, found that type 2 diabetes was linked with an elevated risk of 11 types of cancer in men and 13 types of cancer in women. (2019-05-09)
New cancer therapy target found in mitochondria for potential treatment of blood cancers
A study at The University of Texas MD Anderson Cancer Center identified a new therapeutic target in cancer cells and explains how new anti-cancer drugs called imipridones work by inducing cancer cell death in blood cancers, such as acute myeloid leukemia (AML) and mantle cell lymphoma. (2019-05-02)
Two birds, one stone: Drug combo may prove effective against second type of leukemia
Researchers tested to see if arsenic trioxide (ATO) was effective in combination with all-trans retinoic acid (ATRA) in in both the mouse model of acute myeloid leukemia (AML) and in human AML cells in the lab, and determined that the combination proved 'powerfully and exquisitely effective' against a subset of AML. (2019-04-25)
Targeted therapy proves effective against aggressive rare blood cancer
Clinical study treating BPDCN with tagraxofusp led to first FDA approval for the disease. (2019-04-24)
Study of tagraxofusp reports 90% response rate for deadly blood cancer with no prior available therapies
An open-label, multi-cohort Phase II trial, led by investigators at the University of Texas MD Anderson Cancer Center, reports that treatment with the drug tagraxofusp resulted in high response rates in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare but highly aggressive -- and often fatal bone marrow and blood disorder -- for which there are no existing approved therapies. (2019-04-24)
Overlooked molecular machine in cell nucleus may hold key to treating aggressive leukemia
Many people fighting a very aggressive form of acute myeloid leukemia (AML) don't survive more than five years. (2019-04-22)
The Leukemia Atlas: researchers unveil proteins that signal disease
Only about one in four people diagnosed with acute myelogenous leukemia (AML) survive five years after the initial diagnosis. (2019-04-17)
Probing the mystery of drug resistance: New hope for leukemia's toughest cases
Alejandro Gutierrez, MD, a researcher at the Dana-Farber/Boston Children's Cancer and Blood Disorders Center has made it his mission to figure out why leukemia treatments cure some patients but not others. (2019-04-16)
New hope for treating childhood brain cancer
Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. (2019-04-04)
A step toward recovering reproduction in girls who survive childhood cancer
Leukemia treatments often leave girls infertile, but a procedure developed by researchers at the University of Michigan working with mice is a step toward restoring their ability to be biological mothers. (2019-04-03)
Targeted drug for leukemia tested at Penn Medicine helps patients live longer
An inhibitor drug that targets a specific mutation in relapsed or refractory acute myeloid leukemia (AML) helps patients live almost twice as long as those who receive chemotherapy. (2019-04-01)
Genomic analysis offers roadmap for diagnosis and treatment of a high-risk leukemia
Acute erythroid leukemia (AEL) is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. (2019-03-29)
How 'sleeper cell' cancer stem cells are maintained in chronic myelogenous leukemia
Even when chronic myelogenous leukemia is in remission, 'sleeper cell,' quiescent leukemic stem cells are maintained in microenvironments in the bone marrow. (2019-03-21)
Research paves way for new source for leukemia drug
Chemistry researchers have patented a method for making anti-leukemia compounds that until now have only been available via an Asian tree that produces them. (2019-03-20)
Epigenetic protein could be new therapeutic target in acute myeloid leukemia
British researchers have discovered that an epigenetic protein called EZH2 delays the development of acute myeloid leukemia (AML) but then switches sides once the disease is established to help maintain tumor growth. (2019-03-19)
Genetically encoded sensor isolates hidden leukemic stem cells
Tel Aviv University researchers have devised a novel biosensor that can isolate and target leukemic stem cells. (2019-03-12)
Starving leukemia cells by targeting amino acids
Eliminating ASCT2 selectively stops the growth of leukemia cells, while having limited effects on healthy blood cells and hematopoetic (blood-forming) stem cells. (2019-03-12)
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