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Current Leukemia News and Events

Current Leukemia News and Events, Leukemia News Articles.
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Radiation from CT scans associated with increased risk for cancer
A new study in JNCI Cancer Spectrum finds that exposure to radiation from CT scans is associated with higher risks of developing thyroid cancer and leukemia. (2019-11-19)
Milestone reached in new leukemia drug
Using a chemical compound called YKL-05-099, a team of cancer researchers from CSHL and the Dana Farber Institute was able to target the Salt-Inducible Kinase 3 (SIK3) pathway and extend survival in mice with MLL leukemia. (2019-11-19)
AI-driven single blood cell classification
For the first time, researchers from Helmholtz Zentrum München and the University Hospital of LMU Munich show that deep learning algorithms perform similar to human experts when classifying blood samples from patients suffering from acute myeloid leukemia (AML). (2019-11-12)
Identifying the efficacy of treating encephalitis in leukemia therapy
Revealing the mechanism of glial cell activity...expected to be used for treatment of dementia (2019-11-11)
Lasting tumor regression of leukemia and lymphoma in mouse models achieved by U-M compound
For decades, a transcription factor known as STAT3 has been a major therapeutic target in the treatment of cancer, but it has largely been considered 'undruggable' due to the difficulty of developing compounds to effectively inhibit its activity. (2019-11-11)
Learning to stop cancer at its roots
Leukemia stem cells initiate and sustain leukemia, but researchers have found a way to steer them toward a path of self-destruction. (2019-11-07)
Discovered a new process of antitumor response of NK cells in myeloma
The stem cell transplant and cell immunotherapy group of the Josep Carreras Leukemia Research Institute reveals how NK cells activate a set of actions that promote their antitumor capacity in the presence of myeloma cells. (2019-11-05)
Cocktail proves toxic to leukemia cells
Rice bioscientists find a way to predict the sensitivity of acute myeloid leukemia to mitochondria-damaging molecules and develop cocktails to fight the cancer. (2019-10-31)
Pediatric cancers: Why some forms of leukemia only affect children
Acute myeloid leukemia (AML) mainly affects children, with the prognosis often being poor despite several decades of research into more effective treatments. (2019-10-29)
Treating the TOTAL patient: clinical trial reduces relapse
A St. Jude Children's Research Hospital study lowered the rate of relapse for patients with acute lymphoblastic leukemia. (2019-10-28)
Novel approach identifies factors linked to poor treatment outcomes in ALL
Profiling the metabolites produced in the bone marrow at the time of diagnosis enabled researchers to identify high-risk acute lymphoblastic leukemia (ALL) patients. (2019-10-24)
Cancer treatment: A researcher makes breakthrough immunotherapy discovery
Dr Christopher E. Rudd has discovered a new cell therapy approach that boosts the immune response of T lymphocytes to malignant tumors. (2019-10-24)
'Dietary' vulnerability found in cancer cells with mutated spliceosomes
A research team from the Johns Hopkins Kimmel Cancer Center reports it has discovered a metabolic vulnerability in multiple types of cancer cells that bear a common genetic mutation affecting cellular machines called spliceosomes. (2019-10-03)
How newly found tension sensor plays integral role in aligned chromosome partitioning
A Waseda University-led research found that oncogene SET/TAF1, which was found to be a proto-oncogene of acute myeloid leukemia (AML), contributes to proper chromosome partitioning as a tension sensor. (2019-09-30)
The FASEB Journal: PML as potential treatment for pancreatic cancer
A recent study in The FASEB Journal identifies a new mechanism of pancreatic tumors' resistance to chemotherapeutic treatment. (2019-09-26)
First CAR T cell therapy targeting B cell-activating factor receptor eradicates blood cancers
The first CAR T cell therapy targeting the B cell-activating factor receptor on cancerous cells eradicated CD19-targeted therapy-resistant human leukemia and lymphoma cells in animal models, according to City of Hope research published today in Science Translational Medicine. (2019-09-25)
New CAR T cells could help avoid patient relapse in blood cancers
A research team has created CAR T cells that target an alternative B cell-specific surface marker, allowing them to effectively kill blood cancer cells that lack the prototypical target for CAR T therapy, CD19. (2019-09-25)
Exploring the risk of ALL in children with Down syndrome
Researchers discovered new clues that provide a better understanding of why children with Down syndrome have an increased risk of leukemia. (2019-09-24)
Leukemia drug shows promise for treating a childhood brain cancer
Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer. (2019-09-20)
Infant with deadly leukemia saved by drug for adult liver cancer
Doctors at UCSF Benioff Children's Hospitals have successfully treated an infant with a rare childhood leukemia using a targeted therapy approved for adults with inoperable liver cancer and advanced kidney cancer. (2019-09-11)
NIH, Cincinnati Children's scientists develop possible strategy for cancer drug resistance
NCATS and Cincinnati Children's Hospital Medical Center scientists have devised a potential treatment against leukemia that could have implications for other cancers. (2019-09-04)
Explaining why TP53 is commonly mutated in human cancer, and the effects of its mutation
A comprehensive functional analysis of TP53 mutations in human leukemia may refute a working hypothesis -- primarily based on mouse studies -- that missense mutations confer new cancer-causing functions to the p53 tumor suppressor protein; the new study instead suggests that these mutations exert a 'dominant-negative' effect that reduces the cancer-suppressing activity of wild-type p53, the authors say. (2019-08-08)
Having a parent, sibling, or child with blood cancer increases one's own risk
New data suggest that people who have a parent, sibling, or child with blood cancer have a higher likelihood of being diagnosed with the disease. (2019-08-08)
Combination targeted therapy may offer hope to infants with a deadly type of leukemia
City of Hope researchers have identified a potential combination targeted therapy for a deadly type of leukemia found in some infants, a population too young to receive full-blown chemotherapy. (2019-08-07)
Old cells, new tricks -- important clue to AML diagnosis and cure discovered
Around 22,000 people will be diagnosed this year in the US with acute myeloid leukemia (AML), the second most common type of leukemia diagnosed in adults and children. (2019-08-01)
The drug combination effective against bovine leukemia
Scientists have succeeded in reducing levels of the bovine leukemia virus (BLV) in cows with severe infections by combining an immune checkpoint inhibitor and an enzyme inhibitor. (2019-08-01)
Drug combo heralds major shift in chronic lymphocytic leukemia treatment
A combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and alive longer than the current standard of care, according to a phase-3 clinical trial of more than 500 participants conducted at Stanford Medicine and multiple other institutions. (2019-07-31)
Researchers discover therapy to treat drug-resistant acute lymphoblastic leukemia
Researchers from Case Western Reserve University School of Medicine have developed a new combination treatment regimen that enhances the immune system's ability to kill leukemias that do not respond to standard treatments. (2019-07-29)
Researchers unveil experimental compound to block therapeutic target in blood cancer
UNC Lineberger Comprehensive Cancer Center researchers have discovered a hyperactive cell signal that contributes to tumor growth in primary effusion lymphoma, an aggressive type of non-Hodgkin lymphoma caused by infection with the Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). (2019-07-22)
Many of the deadliest cancers receive the least amount of research funding
Many of the deadliest or most common cancers get the least amount of nonprofit research funding, reports a new Northwestern Medicine study. (2019-07-18)
Making cancer stem cells visible to the immune system
Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. (2019-07-17)
Reversing t cells' misunderstood rep in responding to a pediatric leukemia
A study of pediatric patients with leukemia demonstrates that they were able to generate T cells against tumor-associated mutations, contradicting previous assumptions that T cells cannot be effectively unleashed on pediatric tumors. (2019-06-26)
Tool dearches EHR data to find child leukemia patients for clinical studies
Researchers who analyzed data in the electronic health records of children seen by hematology/oncology specialists at three large medical centers have developed an algorithm to accurately identify appropriate pediatric oncology patients for future clinical studies. (2019-06-26)
A heart failure drug to treat leukemia: A promising new therapeutic approach
Researchers followed their intuition that a drug initially intended for heart failure could be effective in treating cancer. (2019-06-12)
SIRT1 plays key role in chronic myeloid leukemia to aid persistence of leukemic stem cells
Patients with chronic myeloid leukemia are treated with tyrosine kinase inhibitors. (2019-06-10)
New research paves the way for safer leukemia treatments
Researchers have discovered a new, safer way to treat a type of childhood leukaemia: T-cell acute lymphoblastic leukemia (T-ALL). (2019-05-30)
Recovery twice as hard for survivors of childhood acute lymphoblastic leukemia
The cardiorespiratory fitness of survivors of childhood acute lymphoblastic leukemia is 22% worse than that general Canadian population,and genetics might play a role, an UdeM researcher finds. (2019-05-29)
Towards a safer treatment for leukemia
An international team of researchers at VIB-KU Leuven, Belgium, the UK Dementia Institute and the Children's Cancer Institute, Australia, have found a safer treatment for a specific type of leukemia. (2019-05-29)
Study reports ibrutinib and venetoclax combo effective as front-line therapy for select chronic lymphocytic leukemia patients
Ibrutinib and venetoclax, two FDA-approved drugs for treating chronic lymphocytic leukemia (CLL), have been shown to be effective when given together for high-risk and older patients with the disease, according to a study at The University of Texas MD Anderson Cancer Center. (2019-05-29)
Tip sheet: Recent research on how DNA is read and copied
Two scientists at the Johns Hopkins University School of Medicine have unraveled aspects of how DNA organizes and preserves genetic information. (2019-05-22)
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