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Current Lung function News and Events

Current Lung function News and Events, Lung function News Articles.
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Children's noses hold clues to serious lung infections, study shows
Tiny organisms in a child's nose could offer clues to improving the diagnosis and treatment of severe lung infections, research shows. (2019-03-15)
Non-invasive imaging technique valid for identifying small airway disease in lung
Landmark study confirms ability of non-invasive imaging technique to identify early signs of chronic obstructive pulmonary disease (COPD). (2019-03-14)
Study examines use of video-assisted surgery for known, suspected lung cancer in VA
A video-assisted thoracoscopic lung resection is a minimally invasive surgical procedure to remove part of a lung in patients with known or suspected lung cancer. This study used Veterans Affairs data for about 11,000 veterans who had lung resections from 2002 to 2015 to examine adoption of the procedure. (2019-03-13)
Potential cystic fibrosis treatment uses 'molecular prosthetic' for missing lung protein
An approved drug normally used to treat fungal infections could also do the job of a protein channel that is missing or dysfunctional in the lungs of people with cystic fibrosis, operating as a prosthesis on the molecular scale, says new research from the University of Illinois and the University of Iowa. (2019-03-13)
Scientists find new approach that shows promise for treating cystic fibrosis
Researchers say a widely-used antifungal drug may hold promise for treating people with cystic fibrosis, a life-threatening genetic disorder that causes serious damage to the lungs. (2019-03-13)
ZEB1 throttles therapeutic target, protecting KRAS-mutant lung cancer
A cellular identity switch protects a cancer-promoting genetic pathway from targeted therapy, researchers at The University of Texas MD Anderson Cancer Center today reported in Science Translational Medicine. (2019-03-13)
Breath of fresh air in vasculitis research
A University of Tsukuba-led research team revealed that a single-nucleotide polymorphism in the promoter of the MUC5B gene encoding a mucin 5B confers susceptibility to interstitial lung disease (ILD) in Japanese patients suffering from antineutrophil cytoplasmic antibody-associated vasculitis (AAV). (2019-03-12)
Academic performance of urban children with asthma worse than peers without asthma
A new study published in Annals of Allergy, Asthma and Immunology shows urban children with poorly controlled asthma, particularly those who are ethnic minorities, also suffer academically. (2019-03-11)
Imaging technique finds differences between radiation-sensitive and resistant tumors
Researchers have begun pilot clinical trials using an imaging technique called Raman spectroscopy, which offers promise for guided cancer treatment and could spare some patients of the toxic side effects of ineffective radiation therapy. (2019-03-11)
Using precision medicine, researchers discover cause and treatment for specific lung disease
Researchers have identified that dysfunction of a specific immune cell, called B cells, underlies lung disease that affects patients with the rare immunological disorder known as common variable immunodeficiency (CVID). (2019-03-07)
Two for the price of one: Mechanistic insights lead to drug repositioning
A University of Tsukuba-led team confirmed that the binding of the cancer-promoting protein stratifin to phosphorylated SKP1 prevents the formation of a ubiquitinating enzyme complex. (2019-03-07)
Does cognitive function affect oral health during aging?
In a Community Dentistry & Oral Epidemiology study, poor cognitive function in older adults was associated with poorer oral health and higher risk of tooth loss in later life. (2019-03-06)
Smokers often misunderstand health risks of smokeless tobacco product, Rutgers study finds
American smokers mistakenly think that using snus, a type of moist snuff smokeless tobacco product, is as dangerous as smoking tobacco, according to a Rutgers study. (2019-03-04)
A new machine learning model can classify lung cancer slides at the pathologist level
Dartmouth researchers have developed a deep neural network to classify lung cancer subtypes on histopathology slides and found that it performed on par with three practicing pathologists. (2019-03-04)
Breast cancer cells rely on pyruvate to expand in new tissues
Most patients who die of breast cancer die of metastasis, the process by which cancer cells spread to other organs of the body. (2019-03-04)
Pumping iron could save your life
Researchers from Osaka University have found that sarcopenia, a condition characterized by decreased skeletal muscle mass, is strongly associated with poor treatment outcomes in lung cancer patients in response to programed death-1 (PD-1)-inhibitor therapy. (2019-03-04)
Cell atlas of the aging lung
Aging promotes lung function decline and increases susceptibility to diseases of the respiratory tract. (2019-02-28)
New study links electronic cigarettes and wheezing in adults
People who vaped were nearly twice as likely to experience wheezing compared to people who didn't use tobacco products, according to a study published in Tobacco Control. (2019-02-28)
Elucidation of molecular-targeted drug resistance mechanism by lung cancer cells
We revealed that ALK-positive lung cancer cells, treated with crizonitib, a molecular target drug, acquired resistance to the drug not only by genetic mutation but also by concomitant epithelial-to-mesenchymal transition (EMT). (2019-02-25)
Origin of resistance to lung-cancer drug discovered
Researchers at Kanazawa University report in Nature Communications what causes some lung-cancer patients to have an intrinsic resistance to the drug osimertinib: AXL, a protein belonging to the class of receptor tyrosine kinases. (2019-02-25)
New clues about why non-smokers, as well as smokers, develop chronic lung disease revealed
A group of researchers led by the universities of Leicester and Nottingham has discovered genetic differences that put some people at higher risk than others of developing chronic lung disease. (2019-02-25)
Artificial lung cancer tissue could help find new drug treatments
A 3D hydrogel created by researchers at U of T Engineering is helping University of Ottawa researchers to quickly screen hundreds of potential drugs for their ability to fight highly invasive cancers. (2019-02-25)
Treatment to a T? Taking a 'BiTE' out of lung cancer
An Osaka University-led research team assayed T cell cytotoxicity in tumor tissue in lung cancer, along with normal lung tissue and peripheral blood. (2019-02-22)
Correct antibiotic dosing could preserve lung microbial diversity in cystic fibrosis
Children and young adults with cystic fibrosis whose lung infections were treated with suboptimal doses of antibiotics had fewer changes in lung microbial diversity during the IV treatment, and their microbial diversity levels were higher 30 days later, a multi-institutional study that includes Children's researchers shows. (2019-02-22)
Complex medication regimens are common & sometimes dangerous in patients with lung disease
Patients with interstitial lung disease -- a group of disorders causing progressive scarring of lung tissue -- are often prescribed various medications that specifically target their disease and others that treat their symptoms. (2019-02-21)
UBC researchers discover how blood vessels protect the brain during inflammation
Researchers from the University of British Columbia have discovered how blood vessels protect the brain during inflammation -- a finding that could lead to the development of new treatments for neurodegenerative diseases such as stroke, epilepsy and multiple sclerosis. (2019-02-20)
Long periods of sedentary behavior may increase cardiovascular risk in older women
A new study has found that the longer older women sit or lay down during the course of a day -- and the longer the individual periods of uninterrupted sitting--the greater their risk of cardiovascular diseases such as heart disease and stroke. (2019-02-19)
Small cell lung cancer may respond to combination of immunotherapy and DNA damage repair inhibitors
MD Anderson researchers discovered that a combination of immunotherapy and targeted therapies that block normal DNA damage repair, such as PARP inhibitors, achieved dramatic tumor reduction in mouse models of small cell lung cancer. (2019-02-18)
Fetal signaling pathways may offer future targets for treating lung injury
Investigating the fetal signaling pathways active in developing mice may offer future opportunities to treat lung damage caused by prematurity and other lung injuries. (2019-02-18)
Specialized lung cells appear very early in development
Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. (2019-02-18)
More needs to be done to raise awareness of lung cancer risk in people with COPD
People with chronic obstructive pulmonary disease (COPD) need more support when understanding and acting on new chest symptoms, a study in the journal Psycho-Oncology reports. (2019-02-18)
Immune stimulant molecule shown to prevent cancer
An immune checkpoint molecule developed for cancer immunotherapy also protects against future development of multiple types of cancer when administered by itself. (2019-02-15)
Black-white cancer mortality gap nearly eliminated in some age groups
Although African Americans still bear a disproportionate share of the cancer burden, a new report finds the black-white gap has closed considerably over the past several decades. (2019-02-14)
Suspicious spots on the lungs do not behave like metastases of rhabdomyosarcoma
Small spots on CT scans of the lungs of children with muscle cancer do not have an adverse effect on survival according to an international research team in the Journal for Clinical Oncology. (2019-02-14)
New assay selects patients with lung cancer for treatment with immune checkpoint inhibitors
A report in The Journal of Molecular Diagnostics describes a novel and rapid approach for quantifying PD-L1 expression levels in tumors that requires only small amounts of tissue that can be collected using minimally invasive bronchoscopy techniques. (2019-02-13)
New research suggests a simple blood test could improve the early detection of lung cancer
New research led by scientists at the MRC Toxicology Unit suggests that by analysing levels of DNA in the blood, the early detection of lung cancer could be improved. (2019-02-12)
Changes in lung cells seen almost immediately after contact with low-molecular weight PAHs
University of Colorado Cancer Center study shows cancer-promoting changes in lung cells as soon as 30 minutes after exposure to low-molecular weight PAHs, adding further evidence that regulators may be underestimating the risk of these compounds. (2019-02-11)
New heated tobacco device causes same damage to lung cells as e-cigs and smoking
A new study that directly compares new heated tobacco devices with vaping and traditional cigarettes shows that all three are toxic to human lung cells. (2019-02-10)
Researchers develop human cell-based model to study small cell lung cancer
Researchers from Weill Cornell Medicine have used human embryonic stem cells to create a new model system that allows them to study the initiation and progression of small cell lung cancer (SCLC). (2019-02-08)
Financial relationships and prescribing practices between physicians and drug companies
In a study published in The Oncologist, physicians treating certain cancers who consistently received payments from a cancer drug's manufacturer were more likely to prescribe that drug over alternative treatments. (2019-02-06)
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