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Current Lung function News and Events, Lung function News Articles.
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Researchers find clues to SARS-CoV-2 infection, why it impacts patients differently
Previously, scientists have determined that entry of SARS-CoV-2 into cells occurs through a receptor on the cell surface, known as ACE2. (2020-08-11)
The CNIO pave the way for a future gene therapy to reverse pulmonary fibrosis associated with ageing
''Our results indicate that a new therapy may be developed to prevent the development of pulmonary fibrosis associated with ageing,'' says CNIO's Maria Blasco, principal investigator of the study * Lung tissue of patients with pulmonary fibrosis does not regenerate because the cells involved in lung generation have damaged telomeres, the ends of the chromosomes. (2020-08-10)
Change isn't a good thing for Japanese rheumatoid arthritis patients
Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA) that dramatically increases the risk of death. (2020-08-09)
checkmate 743 shows that dual immunotherapy, nivolumab + ipilimumab
The combination of first-line nivolumab and ipilimumab demonstrated an improvement of overall survival for patients with unresectable malignant pleural mesothelioma compared to platinum-based chemotherapy, according to research presented today at the International Association for the Study of Lung Cancer Virtual Presidential Symposium. (2020-08-08)
Phase 3 eXalt3 study shows significantly longer progression-free survival
Patients with non-small cell lung cancer (NSCLC) carrying anaplastic lymphoma kinase (ALK) gene alterations who received ensartinib experienced substantially longer progression-free survival than a matched group of patients who received crizotinib. (2020-08-08)
Addition of sintilimab to pemetrexed and platinum improved progression-free survival
The interim analysis of ORIENT-11, a phase III double-blind randomized trial has shown a nearly two-fold increase in progression-free survival with addition of sintilimab to chemotherapy in patients with advanced or metastatic non-squamous non-small cell lung cancer without EGFR or ALK genomic aberrations, according to research data presented today at the International Association for the Study of Lung Cancer Virtual Presidential Symposium. (2020-08-08)
COVID-19 - The virus and the vasculature
In severe cases of COVID-19, the infection can lead to obstruction of the blood vessels in the lung, heart and kidneys. (2020-08-07)
Pulmonary fibrosis treatment shows proof of principle
A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with idiopathic pulmonary fibrosis (IPF). (2020-08-06)
Lung-specific risk factors may increase hip fracture risk in individuals who smoke
Smoking has been linked to a higher risk of bone fractures. (2020-08-05)
A targeted treatment for emphysema?
Emphysema is a progressive, debilitating lung disease in which the lung's breathing sacs, or alveoli, enlarge, get thinner, and eventually are destroyed as the cells die off. (2020-08-04)
Blood-thinner with no bleeding side-effects is here
In a study led by EPFL, scientists have developed a synthetic blood-thinner that, unlike all others, doesn't cause bleeding side-effects. (2020-08-04)
Assembly within the tumor center
Number of macrophages in tumor tissue enables prognosis of lung tumor progression. (2020-08-04)
Study: Enzyme could prove effective in treating tumors and inflammatory diseases in lung
Findings from a research study led by scientists at Henry Ford suggest an enzyme could play an important role in the treatment of cancer and autoimmune diseases in the airway. (2020-08-04)
Cholesterol-lowering drug improved function of heart's arteries
In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart. (2020-07-29)
Remote, real-time monitoring of post-operative lung transplant patients significantly decreases hospital stays
Remote, real-time monitoring of post-operative lung transplant patients significantly decreases hospital readmissions and resulted in shorter hospital stays when patients were readmitted (2020-07-27)
Drug-induced interstitial lung disease in breast cancer patients
Drug-induced Interstitial Lung Disease in Breast Cancer Patients: A Lesson We Should Learn from Multi-Disciplinary Integration Announcing a new article publication for BIO Integration journal. (2020-07-27)
How airway cells work together in regeneration and aging
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified the process by which stem cells in the airways of the lungs switch between two distinct phases -- creating more of themselves and producing mature airway cells -- to regenerate lung tissue after an injury. (2020-07-27)
Lung ultrasound shows duration, severity of coronavirus disease (COVID-19)
According to an open-access article published in ARRS' American Journal of Roentgenology (AJR), lung ultrasound was highly sensitive for detecting abnormalities in patients with coronavirus disease (COVID-19), with B-lines, a thickened pleural line, and pulmonary consolidation the most commonly observed features. (2020-07-23)
A mouse model was used to determine the personalized treatment for a cancer patient
A team from IDIBELL and ICO, using a mouse orthotopic model, conducted a real-time personalized oncology study to test the best therapeutic option to treat a type of relapse sarcoma. (2020-07-23)
Gene-controlling mechanisms play key role in cancer progression
MIT researchers have analyzed how epigenomic modifications change as tumors evolve. (2020-07-23)
Malaria drug chloroquine does not inhibit SARS-CoV-2
Study shows that chloroquine does not block SARS-CoV-2 infection of lung cells. (2020-07-22)
Using lung X-rays to diagnose COVID-19
This system uses deep learning to train a neural network model that can distinguish between healthy patients, pneumonia patients and COVID-19 patients. (2020-07-21)
An ISGlobal team develops an approach to facilitate the diagnosis of tuberculosis as cause of death
The approach, which combines a simple-to-use molecular test with the minimally invasive autopsy, could be a valuable tool in regions with high burden of the disease (2020-07-16)
Improving lung cancer CT screening performance in real-world settings
An Online First Accepted Manuscript published in ARRS' American Journal of Roentgenology (AJR) finds that focusing on lung cancer screening (LCS) subjects less likely to remain in the program -- those with negative low-dose CT exams and those who still smoke -- can improve that program's cost-effectiveness and maximize its societal benefits. (2020-07-16)
Difference between cystatin C- and creatinine-based eGFRs contains clinical information
It is common to see clinic patients whose eGFR by creatinine and cystatin are different by >15 mL/min. (2020-07-16)
Precision trial highlights need for new approach to treating genomically complex cancers
A pioneering lung cancer study, led by the University of Birmingham's Cancer Research UK Clinical Trials Unit, has highlighted important factors that will need to be considered in the next wave of precision medicine studies particularly in treating genomically complicated cancers. (2020-07-15)
New promising treatment uses smart nanoparticles to target lung cancer
A new and promising approach for treatment of lung cancer has been developed by researchers at Lund University. (2020-07-15)
Severely damaged human lungs can now be successfully recovered
A multidisciplinary team from Columbia Engineering and Vanderbilt University has now demonstrated that severely injured donor lungs that have been declined for transplant can be recovered outside the body by a system that uses cross-circulation of whole blood between the donor lung and an animal host. (2020-07-13)
Human lungs rejected for transplant recovered using novel technique
A multidisciplinary team from Vanderbilt University Medical Center (VUMC) and Columbia University has demonstrated that injured human donor lungs declined for transplant can be recovered by cross-circulation between the human lung and a xenogeneic host. (2020-07-13)
Cystic fibrosis: why so many respiratory complications?
Cystic fibrosis, one of the most common genetic diseases in Switzerland, causes severe respiratory and digestive disorders. (2020-07-13)
International recommendations for nontuberculous mycobacteria
After 13 years, international Infectious Diseases and Respiratory Medicine societies have jointly issued new recommendations for the treatment of patients with nontuberculous mycobacteria (NTM). (2020-07-13)
Yale, Baylor study reveals new cell types in lethal lung disease
A research team from Yale and Baylor College of Medicine has completed the largest single-cell analysis to date of lungs affected by Idiopathic Pulmonary Fibrosis (IPF), revealing how cells change in response to the disease and identifying previously unknown cell types. (2020-07-12)
World-first technology breathes new life into cystic fibrosis detection and treatment
World-first research, led by Monash University, has developed radical non-invasive X-ray technology aimed at helping diagnose, treat and manage people with cystic fibrosis. (2020-07-12)
Lung cancer in non-smokers likely to respond differently to treatment
Lung cancer in non-smokers is a biologically distinct disease from that in smokers, according to a new study. (2020-07-09)
New study supports remdesivir as COVID-19 treatment
The news about remdesivir, the investigational anti-viral drug that has shown early promise in the fight against COVID-19, keeps getting better. (2020-07-09)
New clues to lung-scarring disease may aid treatment
Scientists at Vanderbilt University Medical Center (VUMC) and the Translational Genomics Research Institute (TGen) in Phoenix, Arizona, have discovered previously unreported genetic and cellular changes that occur in the lungs of people with pulmonary fibrosis (PF). (2020-07-08)
Lung, immune function in kids could protect from severe COVID-19
Differences in lung physiology and immune function in children could be why they are more often spared from severe illness associated with COVID-19 than adults. (2020-07-08)
TGen-led study identifies unique cells that may drive lung fibrosis
This is one of the first comprehensive looks at lung cells using a technology called single-cell RNA sequencing. (2020-07-08)
Rheumatoid arthritis patients under treatment with methotrexate
Patients with rheumatoid arthritis (RA) often suffer from what is referred to as interstitial lung disease (ILD). (2020-07-07)
Oncotarget: Australian experience of peptide receptor radionuclide therapy
Oncotarget Volume 11, Issue 27 published ''Australian experience of peptide receptor radionuclide therapy in lung neuroendocrine tumours'' by Lim et al. which reported peptide receptor radionuclide therapy (PRRT) is an approved treatment modality for gastroenteropancreatic neuroendocrine tumours, although Phase III randomised clinical trial data is not available for NETs of other site of origin, in practice, PRRT is used more widely in clinical practice, based on its mechanism of targeting the somatostatin receptor. (2020-07-07)
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