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Current Lymphoma News and Events

Current Lymphoma News and Events, Lymphoma News Articles.
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Radiation from CT scans associated with increased risk for cancer
A new study in JNCI Cancer Spectrum finds that exposure to radiation from CT scans is associated with higher risks of developing thyroid cancer and leukemia. (2019-11-19)
Lasting tumor regression of leukemia and lymphoma in mouse models achieved by U-M compound
For decades, a transcription factor known as STAT3 has been a major therapeutic target in the treatment of cancer, but it has largely been considered 'undruggable' due to the difficulty of developing compounds to effectively inhibit its activity. (2019-11-11)
Penn uncovers dose of medication more likely to put patients with pemphigus into remission
Researchers from Penn compare a lymphoma-dose regimen of rituximab to a rheumatoid arthritis regimen for the treatment of pemphigus. (2019-11-11)
Pattern of hospital visits offers clue to spotting people at risk of myeloma
A condition that can progress to myeloma could be identified in patients by their unusually frequent hospital visits, according to research presented at the 2019 NCRI Cancer Conference. (2019-11-03)
Advanced cancer drug shrinks and intercalates DNA
A new study published in EPJ E has found that the drug first forces itself between the strands of the DNA molecule's double helix, prising them apart. (2019-10-28)
Lymphoma stage at diagnosis may predict when and where new cancer forms
Colorado study shows the stage at which lymphoma is originally diagnosed impacts the types of second cancers that may form after treatment. (2019-10-08)
Cancer data provide insights into occurrence, overdiagnosis, and treatment advances
Investigators analyzed 40 years of cancer burden data and examined patterns of incidence and mortality for various cancers, finding examples for which incidence and mortality moved in concert and examples where discordance in incidence and mortality indicate that overdiagnosis may be at play. (2019-10-02)
First CAR T cell therapy targeting B cell-activating factor receptor eradicates blood cancers
The first CAR T cell therapy targeting the B cell-activating factor receptor on cancerous cells eradicated CD19-targeted therapy-resistant human leukemia and lymphoma cells in animal models, according to City of Hope research published today in Science Translational Medicine. (2019-09-25)
New CAR T cells could help avoid patient relapse in blood cancers
A research team has created CAR T cells that target an alternative B cell-specific surface marker, allowing them to effectively kill blood cancer cells that lack the prototypical target for CAR T therapy, CD19. (2019-09-25)
Biological mechanism explained: How lymphoma cells metastasize to the brain
Scientists at the German Cancer Research Center have now discovered which molecular mechanism leads to lymphomas forming metastases in the central nervous system. (2019-09-16)
CNIO discovers a connection between nutrients and follicular lymphoma
CNIO researchers have identified the role played by mTOR pathway as the origin of follicular lymphoma and propose the exploration in future studies of a possible therapeutic strategy using a drug that is already being used in clinical practice to treat other tumors. (2019-08-21)
A new path to cancer therapy: developing simultaneous multiplexed gene editing technology
Dr. Mihue Jang's group at the Korea Institute of Science and Technology(KIST) announced that they have developed a new gene editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on the surface of lymphoma cells and activation of cytotoxic T lymphocyte, based on the results of joint research conducted with Prof. (2019-08-20)
Nanocapsule reaches cancer that has spread to central nervous system in mice
Researchers developed a drug delivery system that can break through the blood-brain barrier in mice. (2019-08-14)
Having a parent, sibling, or child with blood cancer increases one's own risk
New data suggest that people who have a parent, sibling, or child with blood cancer have a higher likelihood of being diagnosed with the disease. (2019-08-08)
Mount Sinai researchers make immunotherapy work for treatment-resistant lymphoma
Mount Sinai researchers have developed a way to use immunotherapy drugs against treatment-resistant non-Hodgkin's lymphomas for the first time by combining them with stem cell transplantation, an approach that also dramatically increased the success of the drugs in melanoma and lung cancer, according to a study published in Cancer Discovery in July. (2019-08-02)
Simultaneous infection by 2 viruses the key to studying rare lymphoma
New research has found that a rare blood cancer can be simulated in the lab only by simultaneously infecting white blood cells with 2 viruses typically found in the tumors. (2019-07-29)
Antibiotics can inhibit skin lymphoma
New research from the LEO Foundation Skin Immunology Research Center at the University of Copenhagen shows, surprisingly, that antibiotics inhibit cancer in the skin in patients with rare type of lymphoma. (2019-07-25)
Association of BRCA2 mutations with risk of childhood lymphoma
This research letter reports on the association of BRCA2 gene mutations and potential risk for pediatric or adolescent lymphoma. (2019-07-25)
Inherited BRCA2 mutations linked to increased risk of childhood lymphoma
A report from St. Jude Children's Research Hospital links inherited mutations in the BRCA2 gene with an increased risk of developing non-Hodgkin lymphoma in children and adolescents. (2019-07-25)
Researchers unveil experimental compound to block therapeutic target in blood cancer
UNC Lineberger Comprehensive Cancer Center researchers have discovered a hyperactive cell signal that contributes to tumor growth in primary effusion lymphoma, an aggressive type of non-Hodgkin lymphoma caused by infection with the Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). (2019-07-22)
Many of the deadliest cancers receive the least amount of research funding
Many of the deadliest or most common cancers get the least amount of nonprofit research funding, reports a new Northwestern Medicine study. (2019-07-18)
Depression is common and linked with early death in patients with blood cancers
In a Psycho-Oncology study of patients newly diagnosed with lymphoma or multiple myeloma, one-third of participants reported depressive symptoms around the time of diagnosis, and depressive symptoms were linked with shorter survival. (2019-07-03)
High doses of 60 plus-year-old chemo drug found to spur immune system attack on lymphoma
Cyclophosphamide, a mainstay of chemotherapy for many cancers, acts as both chemotherapy and immunotherapy at high doses, study finds. (2019-07-01)
Researchers unlock mysteries of complex microRNA oncogenes
A new collaborative study, led by researchers at McGill University's Goodman Cancer Research Centre (GCRC), and published in the journal Molecular Cell, uncovers novel functions for polycistronic microRNAs and showing how cancers such as lymphoma twist these functions to reorganize the information networks that control gene expression. (2019-06-27)
Tool dearches EHR data to find child leukemia patients for clinical studies
Researchers who analyzed data in the electronic health records of children seen by hematology/oncology specialists at three large medical centers have developed an algorithm to accurately identify appropriate pediatric oncology patients for future clinical studies. (2019-06-26)
Immunotherapy and HDAC inhibition are anti-cancer besties
Colorado study shows that adding HDAC inhibitor sensitized cancers to anti-PD1 therapy. (2019-06-24)
Cancer survival rates in the young show inconsistent progress
A new study in JNCI Cancer Spectrum finds that dramatic increases in cancer survival in adolescents and young adults are undermined by continuing disparities by race, ethnicity, and socioeconomic status. (2019-06-12)
Lymphoma trial finds combination targeted therapy effective prior to chemotherapy
Results of a Phase II clinical trial conducted at The University of Texas MD Anderson Cancer Center revealed that combination targeted therapy, consisting of rituximab, lenalidomide and ibrutinib (RLI), had an 84.6 percent overall response rate (ORR) and 38.5% complete response rate (CRR) when given prior to any chemotherapy for newly diagnosed patients with a specific type of diffuse large b-cell lymphoma (DLBCL). (2019-06-04)
Researchers identify new roles for common oncogene MYC
Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US every year. (2019-05-29)
New evidence supports surgery for rare type of brain lymphoma
Through a systematic review of published studies going back 50 years, Johns Hopkins Medicine researchers say they have identified a distinct subtype of primary central nervous system (PCNS) lymphoma that should be considered for surgical removal, suggesting a major shift in how this type of tumor is evaluated and managed. (2019-05-28)
CNIO participates in a study identifying a novel oncogene for most common types of blood cancer
The study shows that tumour suppressor hnRNP K can lead to cancer. (2019-05-24)
Allogeneic stem cell transplantation in non-Hodgkin lymphoma: benefit remains unclear
Meaningful studies are lacking for certain patient groups. Disease-specific registries could help close the data gap. (2019-05-23)
Researchers pinpoint why lymphoma patients may become resistant to specific therapy
Researchers from Moffitt Cancer Center and Dana-Farber Cancer Institute have discovered a mechanism of drug resistance to Venetoclax®, also known as ABT-199, a BCL-2 targeting drug commonly used to treat chronic lymphocytic leukemia and acute myeloid leukemia. (2019-05-15)
What are the neurological side effects of CAR T-cell therapy?
A team at Brigham and Women's Hospital recently cataloged the neurological symptoms of patients who had received CAR T-cell therapy to better understand its neurotoxic side effects. (2019-05-15)
Why Hodgkin's lymphoma cells grow uncontrollably
Although classical Hodgkin's lymphoma is generally easily treatable today, many aspects of the disease still remain a mystery. (2019-05-13)
Diabetes linked to numerous cancers in large Chinese study
A new Journal of Diabetes study from China, which has the highest number of people with diabetes among all countries, found that type 2 diabetes was linked with an elevated risk of 11 types of cancer in men and 13 types of cancer in women. (2019-05-09)
Study shows MD Anderson-developed drug effective in overcoming ibrutinib resistance in mantle cell lymphona
A study at The University of Texas MD Anderson Cancer Center demonstrated how a small molecule drug discovered at the institution may help overcome resistance to treatment with ibrutinib in patients with mantle cell lymphoma. (2019-05-08)
New cancer therapy target found in mitochondria for potential treatment of blood cancers
A study at The University of Texas MD Anderson Cancer Center identified a new therapeutic target in cancer cells and explains how new anti-cancer drugs called imipridones work by inducing cancer cell death in blood cancers, such as acute myeloid leukemia (AML) and mantle cell lymphoma. (2019-05-02)
Radiotherapy after chemo may improve survival in patients with advanced Hodgkin's lymphoma
Patients with advanced Hodgkin's lymphoma who have large tumors at the time of diagnosis may benefit from radiotherapy after chemotherapy even when all traces of the cancer appear to have gone, according to late-breaking results presented at the ESTRO 38 conference. (2019-04-28)
Researchers devise a progression risk-based classification for patients with AWM
Researchers at Dana-Farber Cancer Institute have devised a risk model for determining whether patients with AWM have a low, intermediate, or high risk of developing symptomatic Waldenström macroglobulinemia. (2019-04-23)
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