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Current Macrophages News and Events

Current Macrophages News and Events, Macrophages News Articles.
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Age research: A low level of the stress hormone cortisol contributes to the ageing process
Why do we age? What exactly is happening in our bodies? (2020-07-01)
Implants: Can special coatings reduce complications after implant surgery?
New coatings on implants could help make them more compatible. (2020-06-30)
Immune cells infiltrating tumors may play bigger cancer role than previously thought
UC San Diego researchers uncovered in mice how IRE1α, a molecule involved in cells' response to stress, determines whether macrophages promote inflammation in the tumor microenvironment. (2020-06-22)
Re-trafficking proteins to fight Salmonella infections
New study demonstrates how monitoring all cellular proteins over time and space can improve our understanding of host-pathogen interactions. (2020-06-09)
Photodynamic therapy used to treat ovarian cancer
Photodynamic therapy (PDT) is one of the most promising methods of treating localized tumors. (2020-06-08)
Approved drug may help calm cytokine storm in COVID-19
The drug acalabrutinib, FDA-approved for the treatment of several types of B cell cancers, improved the oxygenation levels and decreased molecular markers of inflammation in a majority of 19 patients hospitalized for the treatment of severe COVID-19, according to a new study by Mark Roschewski and colleagues. (2020-06-05)
Ludwig Lausanne study charts the immune landscape of multiple brain cancers
A Ludwig Cancer Research study has profiled, in a sweeping comparative analysis, the distinct immune landscapes of tumors that arise in the brain, or gliomas, and those that metastasize to the organ from the lungs, breast and skin. (2020-05-28)
Stimulating immune cleanup crew offers a possibility for treating rare disorder
Compounds that mimicked the process known as efferocytosis alleviated signs of leukocyte adhesion deficiency type-1 in an animal model, according to work led by the University of Pennsylvania's George Hajishengallis. (2020-05-26)
Preventing 'cytokine storm' may ease severe COVID-19 symptoms
A clinical trial in people with the new coronavirus is testing a drug that may halt an overactive immune response before it ramps up. (2020-05-21)
PD-1/PD-L1 inhibitors treatment in lung cancer: Brightness and challenge
Immune-checkpoint inhibitors (ICIs) have made a significant impact on the outcomes of lung cancer patients. (2020-05-18)
Not all multiple sclerosis-like diseases are alike
Scientists say some myelin-damaging disorders have a distinctive pathology that groups them into a unique disease entity. (2020-05-18)
'Cells-soldiers' turned to be more resistant than 'cells-combat medics'
Researchers from Sechenov University (Russia) and University of Pittsburgh (USA) discovered that the resistance of innate immune cells, macrophages, to ferroptosis -- a type of programmed cell death -- depends on the type of their activation. (2020-05-16)
Platelets exacerbate immune response
Platelets not only play a key role in blood clotting, but can also significantly intensify inflammatory processes. (2020-05-12)
The challenges of developing a safe and effective COVID-19 vaccine
Researchers at Baylor College of Medicine and colleagues identify critical points to pay close attention to when designing and developing COVID-19 vaccines. (2020-05-12)
Blood cells could serve as a 'thermometer' to detect breast cancer
This study shows that patients develop alterations in a type of leukocyte at the initial stage of the disease. (2020-05-12)
Researchers ID target for colorectal cancer immunotherapy
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a target for colorectal cancer immunotherapy. (2020-05-11)
Newly discovered cell type plays crucial role in immune response to respiratory infections
With a discovery that could rewrite the immunology textbooks, an international group of scientists, including the teams of Bart Lambrecht, Martin Guilliams, Hamida Hammad, and Charlotte Scott (all from the VIB-UGent Center for Inflammation Research) identified a new type of antigen-presenting immune cell. (2020-05-08)
UB investigators uncover cellular mechanism involved in Krabbe disease
Researchers determined which cells are involved in Krabbe disease and by which mechanism. (2020-05-05)
Biomaterial immune control discoveries could reduce implant rejection
Scientists have discovered how the materials used in medical implants like artificial joints can be adapted to control the immune response to them and reduce the risk of rejection. (2020-05-04)
'Backpacks' boost immune cells' ability to kill cancer
Macrophages are the body's search-and-destroy defense force, but cancerous tumors hijack arriving macrophages by switching them into a pro-cancer state. (2020-04-29)
New type of immune cell discovered in breast ducts
Melbourne breast cancer researchers have discovered a new type of immune cell that helps to keep breast tissue healthy by regulating a vital process within mammary ducts - the sites where milk is produced and transported, but also where most breast cancers arise. (2020-04-27)
New active ingredient against allergic asthma
Our immune system protects us against pathogens. However, an excessive immune reaction can trigger allergies or chronic asthma. (2020-04-24)
High ferritin levels may indicate severe COVID-19
Professor Yehuda Shoenfeld is Head of the Laboratory of the Mosaic of Autoimmunity at St Petersburg University and founder and Head of the Zabludowicz Center for Autoimmune Diseases (Israel). (2020-04-22)
UofL researchers describe possible mechanism for link between obesity and breast cancer
It is widely accepted that higher levels of body fat increase the risk of developing breast cancer, as well as other cancers. (2020-04-13)
Vulnerable cells armor themselves against infection by depleting surface cholesterol
Cells in some of the body's most vulnerable entry routes to bacterial infection buffer themselves when the immune system detects danger by reorganizing the cholesterol on their surfaces, a new study led by UTSW scientists suggests. (2020-04-13)
New molecular mechanism that regulates the sentinel cells of the immune system
CNIC scientists have uncovered a new molecular mechanism that determines the identity and expansion of one of the cell types that work as immune sentinels in the body -- the macrophages of the serous cavities. (2020-04-03)
New type of immunotherapy hinders the spread of ovarian cancer
Malignant ovarian cancer is insidious: Known and feared for vague and uncharacteristic symptoms that often mean the disease is discovered so late that on average only four out of six patients are still alive after five years. (2020-03-26)
A study investigating genetic mechanisms underlying resistance to leishmaniasis
The study was conducted in Brazil and mapped the genes that are activated when mice resistant to Leishmania are infected. (2020-03-24)
CAR macrophages go beyond T cells to fight solid tumors
Penn Medicine research shows genetically engineering macrophages -- an immune cell that eats invaders in the body -- could be the key to unlocking cellular therapies that effectively target solid tumors (2020-03-23)
A new strategy for the management of inflammatory pain
A group of researchers from Charité - Universitätsmedizin Berlin has discovered a new mechanism of long-lasting pain relief. (2020-03-16)
Intralipid improves efficacy of chemotherapy treatment
Pairing chemotherapy nanodrugs with a nutritional supplement can lessen devastating side-effects while reducing the amount of the expensive drugs needed to treat cancer according to a study from Carnegie Mellon University and Taiwan's National Health Research Institutes. (2020-03-10)
Engineered bone marrow cells slow growth of prostate and pancreatic cancer cells
In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response. (2020-03-05)
Hydrogen sulfide heightens disease in tuberculosis, suggesting a new therapeutic target
A new culprit -- hydrogen sulfide -- has been found for the deadly infectious disease tuberculosis. (2020-03-03)
Researchers identify protein critical for wound healing after spinal cord injury
Plexin-B2, an axon guidance protein in the central nervous system (CNS), plays an important role in wound healing and neural repair following spinal cord injury (SCI), according to research conducted at the Icahn School of Medicine at Mount Sinai and published today in Nature Neuroscience (2020-03-02)
Imaging can guide whether liquid biopsy will benefit individual glioblastoma patients
New research shows brain imaging may be able to predict when a blood test known as a liquid biopsy would or would not produce clinically actionable information, allowing doctors to more efficiently guide patients to the proper next steps in their care. (2020-02-27)
Study unravels how our immune system deals with fungal and viral infections
The body's immune response to fungal infections changes when a patient is also infected by a virus, according to new research which investigated the two types of infection together for the first time. (2020-02-27)
Possible new treatment strategy for fatty liver disease
Researchers at Karolinska Institutet in Sweden have identified a molecular pathway that when silenced could restore the normal function of immune cells in people with fatty liver disease. (2020-02-26)
Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization
The insulin-producing beta cells in the pancreas unwittingly produce a signal that may aid their own demise in Type 1 diabetes, according to a study of the lipid signals that drive macrophage cells in the body to two different phenotypes of activated immune cells. (2020-02-21)
Immune cells consult with neighbors to make decisions
Researchers have uncovered new evidence that immune cells count their neighbors before deciding whether or not the immune system should kick into high gear. (2020-02-13)
Stroke: Macrophages migrate from the blood
Macrophages are part of the innate immune system and essential for brain development and function. (2020-02-11)
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