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Current Macrophages News and Events

Current Macrophages News and Events, Macrophages News Articles.
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New discovery points toward possible treatment for diabetic non-healing wounds
A new mouse and human tissues study identifies an enzyme critical for normal wound healing that may open up avenues for treatment. (2019-07-23)
MicroRNAs from human fat cells can impair macrophage ability to eliminate cholesterol
A multi-institutional team led by research faculty at Children's National in Washington, DC, finds that extracellular vesicles (EVs) derived from kids' fat can play a pivotal role in ratcheting up risk for atherosclerotic cardiovascular disease well before any worrisome symptoms become visible. (2019-07-23)
How DNA outside cells can be targeted to prevent the spread of cancer
Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes. (2019-07-11)
Endometriosis: Immune cell discovery could provide relief for women with 'hidden' pain disorder
A key cause for the pelvic pain experienced by women with endometriosis has been uncovered, potentially opening new opportunities for pain relief for the condition. (2019-07-11)
How plague pathogens trick the immune system
Yersinia have spread fear and terror, especially in the past, but today they have still not been completely eradicated. (2019-07-11)
In cases when patients under anesthesia experience anaphylaxis, hyperactive immune...
A study of 86 patients reveals how drugs used for anesthesia can induce life-threatening anaphylaxis (a dangerous type of allergic reaction) through an alternative immune pathway. (2019-07-10)
Caspase-1 initiates apoptosis, but not pyroptosis, in the absence of gasdermin D
Caspase-1 triggers programmed necrosis called pyroptosis by gasdermin-D (GSDMD) cleavage. (2019-07-05)
Reprogramming pancreatic cancer
A type of white blood cell that has been especially susceptible to being deceived by pancreatic cancer cells into not attacking them can be 're-programmed' via a specially designed molecule that activates a protein found on their surfaces. (2019-07-03)
Researchers at IDIBELL-ICO describe a new resistance mechanism
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) and the ProCure Program of the Catalan Institute of Oncology (ICO) published today at Cancer Research a study describing a new mechanism in cancer that turns cells into malignant cells and contradicts what had been published so far about drug resistance that prevent the formation of blood vessels (anti-angiogenics). (2019-07-02)
High doses of 60 plus-year-old chemo drug found to spur immune system attack on lymphoma
Cyclophosphamide, a mainstay of chemotherapy for many cancers, acts as both chemotherapy and immunotherapy at high doses, study finds. (2019-07-01)
A Trojan horse? Immune cells ferry deadly fungus from mouse lung into the blood
A report today (June 27) in PLOS Pathogens shows how inhaled fungal spores exit the lung and trigger a fatal infection in mice. (2019-06-27)
New method reveals how well TB antibiotics reach their targets
Scientists have developed a new technique that enables them to visualise how well antibiotics against tuberculosis (TB) reach their pathogenic targets inside human hosts. (2019-06-27)
Scientists track brain tumor turncoats with advanced imaging
To better understand the cells that brain tumors recruit, scientists developed advanced imaging techniques to visualize macrophages. (2019-06-25)
How bacteria kill host cells from the inside
A bacterial pathogen that typically multiplies outside of host cells can enter and induce the destruction of cells called macrophages, according to a study published June 20, 2019 in the open-access journal PLOS Pathogens by Anne-Béatrice Blanc-Potard of the Université de Montpellier in France, and colleagues. (2019-06-20)
Study: Phenols in cocoa bean shells may reverse obesity-related problems in mouse cells
A new study by researchers at the University of Illinois suggests that three of the phenolic compounds in cocoa bean shells have powerful effects on the fat and immune cells in mice, potentially reversing the chronic inflammation and insulin resistance associated with obesity. (2019-06-20)
Research highlights possible targets to help tackle Crohn's disease
There is no precise cure for digestive condition Crohn's disease, and causes are believed to vary. (2019-06-17)
Researchers identify enzyme that suppresses immune system in breast cancer
Duke Cancer Institute researchers outlined a potential way to uncloak breast cancer tumors to the body's immune system. (2019-06-17)
Cardiovascular diseases -- Promoting self-healing after heart attack
Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Oliver Söhnlein have shown that a protein which stimulates the resolution of inflammatory reactions enhances cardiac repair following heart attack in both mice and pigs. (2019-06-11)
Study finds macrophages' pathway to nurture PTEN-deficient glioblastoma
A common genetic deficiency empowers glioblastoma to broadcast a molecular message to the wrong type of immune cell, summoning macrophages that protect and nurture the brain tumor instead of attacking it, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Cell. (2019-06-10)
Molecular chatter makes for a 'hot tumor'
A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells. (2019-06-10)
Immune cells play unexpected role in early tuberculosis infection
A class of immune cells called innate lymphoid cells (ILCs) mediates the body's initial defense against TB, according to a report published online today in Nature. (2019-06-05)
'Cannibalism' is a double-whammy for cell health
University of Sydney mathematician Hugh Ford has developed a model tested by experiment that shows cell cannibalism is an important driver in the build-up of cholesterol and other harmful materials. (2019-06-04)
When macrophages are deprived of oxygen
Infected tissue has a low concentration of oxygen. The body's standard immune mechanisms, which rely on oxygen, can then only function to a limited extent. (2019-05-24)
New understanding of how cells form tunnels may help in treating wounds, tumors
'A major aspect of our research is that it just really illustrates how complex all these different components are going on inside a person's body,' said Andrew Ford. (2019-05-23)
Canadian researchers on promising path towards developing flu treatment using lipid target
A team of scientists of the Research Institute of the McGill University Health Centre (RI-MUHC) in Montreal, Canada , has tackled this fundamental question and recently identified a target to 'tone down' the hyper-active immunity to influenza infection. (2019-05-22)
Dead cells disrupt how immune cells respond to wounds and patrol for infection
Immune cells prioritise the clearance of dead cells overriding their normal migration to sites of injury. (2019-05-21)
Preventing cell death as novel therapeutic strategy for rheumatoid arthritis
A collaborative study by research groups from the University of Cologne, VIB, Ghent University, the Βiomedical Sciences Research Center 'Alexander Fleming' in Athens and the University of Tokyo identified a new molecular mechanism causing rheumatoid arthritis. (2019-05-13)
A link between mitochondrial damage and osteoporosis
In healthy people, a tightly controlled process balances out the activity of osteoblasts, which build bone, and osteoclasts, which break it down. (2019-05-09)
HSS researchers advance understandings of the cellular mechanisms driving rheumatoid arthritis
Newly identified subsets of cell types present in the joint tissue of rheumatoid arthritis (RA) patients, and how they interact may help develop future precision medicine strategies. (2019-05-09)
Detailed brain map uncovers hidden immune cells that may be involved in neurodegenerative disorders
Our brains do not only contain neurons, but also a variety of immune cells that play an important role for its functioning. (2019-05-06)
Obesity reprograms immune cells in breasts to promote tumor formation
Macrophages in adipose tissue (fat) link obesity to triple-negative breast cancer. (2019-05-06)
Study in mice uncovers an unknown pathway for breast cancer tumors to recur
Experimenting in mice, the researchers tracked a series of events that enable a small reservoir of treatment-resistant cancer cells to awake from dormancy, grow and spread. (2019-04-25)
Researchers learn how 'bad cholesterol' enters artery walls
UT Southwestern researchers have determined how circulating ''bad cholesterol'' enters artery walls to cause the plaque that narrows the blood vessels and leads to heart attacks and strokes. (2019-04-24)
Scientists report new approach to reduce or prevent renal fibrosis
Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure. (2019-04-16)
Precise decoding of breast cancer cells creates new option for treatment
Researchers at the University of Zurich and from IBM Research have investigated the vary-ing composition of cancer and immune cells in over one hundred breast tumors. (2019-04-15)
Bacteria flip an electric switch to worsen food poisoning
Salmonella bacteria flip an electric switch as they hitch a ride inside immune cells, causing the cells to migrate out of the gut toward other parts of the body, according to a new study publishing on April 9 in the open-access journal PLOS Biology by Yaohui Sun and Alex Mogilner of New York University and colleagues. (2019-04-09)
Immune cells key to predicting cancer outcomes, research suggests
Scientists have identified key changes in immune cells within cancerous tumors that could help improve the development of treatments. (2019-04-05)
Microglia, cells thought restricted to central nervous system, are redefined in new study
Scientists at the University of Notre Dame discovered microglia actually squeeze through the spinal boundary, crossing into the peripheral nervous system in response to injury. (2019-04-04)
Sugar could be sweet solution to respiratory disease
Restriction or inhalation of common sugar could one day treat a range of respiratory diseases, according to new research led by University of Manchester biologists. (2019-04-01)
New gene potentially involved in metastasis identified
Cancers that display a specific combination of sugars, called T-antigen, are more likely to spread through the body and kill a patient. (2019-03-26)
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